carotid stenosis

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Information
Disease name
carotid stenosis
Disease ID
DOID:13001
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06315153 Active, not recruiting Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model January 3, 2022 April 1, 2026
NCT04201132 Active, not recruiting N/A Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System June 12, 2020 December 2025
NCT00004732 Completed N/A Carotid Revascularization Endarterectomy Versus Stenting Trial December 2000 December 2016
NCT00005348 Completed Adipose Distribution and Atherosclerosis April 1991 March 1993
NCT00005399 Completed Cohort Study of Heart Rate Variability August 1996 June 2001
NCT00005412 Completed Dietary Antioxidants and Atherosclerosis July 1992 June 1995
NCT00011258 Completed Paraoxonase and LDL Oxidation in Carotid Artery Disease March 1997 September 2003
NCT00000469 Completed Phase 2 Asymptomatic Carotid Artery Plaque Study (ACAPS) May 1988 August 1998
NCT06401902 Completed Diabetes and Risk of Ischemic Stroke. January 1, 1990 June 30, 2019
NCT00178672 Completed Phase 4 A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease November 2002 August 2007
NCT00190398 Completed Phase 3 EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis November 2000 December 2009
NCT00287508 Completed Phase 4 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) November 2005 January 2008
NCT05739357 Completed N/A Neurocognitive Function After Carotid Thrombendarterectomy August 1, 2019 October 1, 2023
NCT05652426 Completed The Effect of Hypoxic and Normoxic Cerebral Oximetry Levels on Cognitive Functions After Carotid Endarterectomy January 1, 2021 January 1, 2022
NCT05437991 Completed N/A Ultrasonographic Morphology Assessment of Low-grade Carotid Stenosis September 29, 2022 January 12, 2023
NCT00417586 Completed Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke June 2007 November 2010
NCT05355259 Completed N/A ACtive Catheterization for EndovaScular TreatmentS June 27, 2022 August 5, 2022
NCT00536796 Completed Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets September 2007 December 2007
NCT00536965 Completed Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets July 2007 December 2007
NCT05134493 Completed Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation June 27, 2018 June 30, 2021
NCT04845334 Completed N/A Complementary and Alternative Medicine Interventions in Targeting Pain January 2015 June 2017
NCT04835571 Completed N/A CARotid Mri of Atherosclerosis January 6, 2017 December 31, 2021
NCT00772278 Completed Phase 4 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis January 2009 September 2015
NCT00830232 Completed N/A Effects of Carotid Stent Design on Cerebral Embolization December 2008 February 2012
NCT04662177 Completed Phase 4 Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA) November 21, 2018 December 4, 2020
NCT04553549 Completed Safety and Feasibility of the Infinity Catheter for Radial Access October 1, 2020 October 30, 2022
NCT00976014 Completed Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study December 26, 2006 May 9, 2012
NCT01064908 Completed A New Oxygen Mask for Carotid Endarterectomy Under Local Anaesthesia January 2010 March 2012
NCT04326842 Completed Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis April 2, 2020 July 2, 2020
NCT01133327 Completed N/A Adapt Monorail Carotid Stent System: A Postmarket Clinical Follow-up Study June 2010 June 2012
NCT01146301 Completed Phase 4 Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery March 2008 April 2010
NCT04255316 Completed N/A Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carotid Bifurcation October 1, 2017 March 1, 2020
NCT01224600 Completed EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs January 2008 March 2014
NCT03985774 Completed The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study February 26, 2015 March 25, 2021
NCT01274676 Completed N/A Carotid Stenting in Patients With High Risk Carotid Stenosis ("Soft Plaque") February 2009 February 2010
NCT01315288 Completed N/A A Randomized Trial of Clinical Decision Making in Asymptomatic Carotid Stenosis October 2008 August 2010
NCT01337128 Completed N/A Carotid Endarterectomy Versus Carotid Artery Stenting? A Prospective Comparison of Neuropsychological Outcome in Patients With Carotid Stenosis. April 2011 September 2015
NCT01343667 Completed N/A GORE Flow Reversal System and GORE Embolic Filter Extension Study April 2011 January 2014
NCT01344447 Completed Phase 3 Gadobutrol Enhanced MRA of the Supra-aortic Vessels May 12, 2011 May 28, 2014
NCT03982420 Completed The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Evaluation June 27, 2019 January 19, 2022
NCT01456403 Completed Histological Validation Of Carotid Plaque Composition In Preoperative Imaging January 2011 January 2016
NCT01480206 Completed Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR September 13, 2011 August 1, 2021
NCT03936881 Completed Carotid Region Calcifications and Orthopantomogram May 6, 2019 July 10, 2019
NCT01569594 Completed CorMatrix ECM for Carotid Repair Following Endarterectomy Registry April 2012 December 31, 2016
NCT03596229 Completed Major Adverse Cardiac Events After Carotid Endarterectomy October 1, 2018 January 15, 2020
NCT03410576 Completed Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy October 1, 2013 November 30, 2015
NCT03303534 Completed N/A Short-Term Endogenous Hydrogen Sulfide Upregulation September 14, 2017 June 1, 2018
NCT01645306 Completed Phase 2 Revacept in Symptomatic Carotid Stenosis March 8, 2013 September 23, 2019
NCT03234257 Completed N/A Evaluation of the Carotid Plaque Stability by Ultrafast-ultrasound Imaging (UF) May 18, 2017 September 30, 2020
NCT03215563 Completed PET-MRI Imaging in Patients With Acute Neurovascular Syndrome October 12, 2017 January 10, 2020
NCT01873716 Completed Phase 1 Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque May 2013 January 2016
NCT01889485 Completed Screening and Access to Health Care for Vascular Disease June 1, 2014 May 2021
NCT01897103 Completed Platelet Activity in Vascular Surgery for Thrombosis and Bleeding June 2013 December 2017
NCT01958294 Completed N/A The MICHI NEUROPROTECTION SYSTEM: Evaluation of Performance in Carotid Artery Stent Procedures (The LOTUS Study) August 2011 August 2014
NCT03215550 Completed PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis October 12, 2017 January 10, 2020
NCT03202823 Completed Arachidonic Acid Metabolism in Carotid Stenosis Plaque in Diabetic Patients April 13, 2017 December 11, 2020
NCT03115034 Completed Phase 4 Melatonin in Patients Under Carotid Endarterectomy June 1, 2016 November 1, 2017
NCT02118233 Completed Cognitive Outcome After Carotid Surgery April 2014 November 2019
NCT02808754 Completed N/A Remote Ischemic Preconditioning for Carotid Endarterectomy December 2016 January 2019
NCT02230358 Completed N/A Cardiac Output and Duplex Sonography in Carotid Endarterectomy July 2014 July 2017
NCT02260453 Completed Phase 3 Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease January 2005 June 2012
NCT02310191 Completed Correlation Between Laboratory Markers and Origin of New Brain Ischemic Lesions After Carotid Stenting July 2012 November 2014
NCT02336958 Completed N/A Ultrasound Guided Intermediate Cervical Plexus Block and Additional Perivascular Local Anesthetic Infiltration September 2013 December 2014
NCT02341664 Completed Patient and Provider Assessment of Lipid Management Registry May 2015 February 2016
NCT02436967 Completed Classification of Carotid Plaque With Computed Tomography With Fast kVp (Kilovolt Peak)-Switching Technique December 2014 March 2021
NCT02722720 Completed N/A Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral September 2015 December 2016
NCT02609087 Completed Phase 4 Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy August 2015 December 2016
NCT02630862 Completed N/A Oxidative Stress and Oxysterols Profiling in Patients With Carotid Revascularization September 2010 December 2014
NCT00000527 Completed Phase 2 Recurrent Carotid Stenosis August 1986 November 1998
NCT06452173 Enrolling by invitation Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis April 15, 2024 December 31, 2026
NCT05850247 Not yet recruiting Phase 2 Plaque and Brain Inflammation in Symptomatic Carotid Stenosis: Role of the Ficolin-2 August 1, 2023 January 30, 2025
NCT05980195 Not yet recruiting N/A Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial April 9, 2024 December 31, 2025
NCT04904250 Not yet recruiting N/A Spider Versus Emboshield Distal Protection on Cerebral Microembolization During Vulnerable Plaque in Carotid Artery Stenting August 27, 2022 October 1, 2024
NCT05905848 Not yet recruiting Phase 3 Pre-operative Antihypertension Strategies-Carotid Artery Stenting June 15, 2023 July 31, 2025
NCT04261478 Recruiting N/A Endovascular Acute Stroke Intervention - Tandem OCclusion Trial August 31, 2020 March 2027
NCT02476396 Recruiting Structural Stability of Carotid Plaque and Symptomatology November 9, 2015 December 2025
NCT05931003 Recruiting N/A Reconstruction of the Carotid Bifurcation in Patients With Arterial Hypertension of 2-3 Degrees July 1, 2022 September 1, 2025
NCT01732523 Recruiting Predictive Value of Neovascularization Within Asymptomatic Carotis Stenosis on CEUS October 2012 December 2027
NCT02748941 Recruiting N/A Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control January 12, 2017 February 12, 2025
NCT06294496 Recruiting Study of Carotid Artery Stenosis Through the Integration of Multimodal Imaging and Computational Fluid Dynamics June 1, 2023 December 31, 2024
NCT05845710 Recruiting N/A Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III) October 5, 2023 May 2025
NCT05835869 Recruiting N/A Chorioretinal Vascularization and Electrophysiological Changes After Carotid Revascularization April 20, 2023 April 30, 2024
NCT05797376 Recruiting Phase 4 Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation August 24, 2021 June 2025
NCT05623293 Recruiting Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis January 1, 2022 December 31, 2023
NCT06207643 Recruiting N/A Comparison Between Different Techniques for Carotid Artery Endarterectomy February 2024 February 2025
NCT05599009 Recruiting N/A Remote Ischemic Conditioning and Dynamic Cerebral Autoregulation in Patients With Intracranial and Extracranial Arteriosclerosis December 10, 2022 February 28, 2023
NCT05566301 Recruiting Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA) September 2, 2021 December 31, 2026
NCT05524207 Recruiting Carotid Artery Stent Implantation in the Treatment of Vulnerable Plaque January 1, 2022 December 30, 2024
NCT05416853 Recruiting N/A Radial Versus Femoral Access For Carotid Artery Stenting July 4, 2022 September 3, 2024
NCT05300737 Recruiting Symptomatic Carotid Outcomes Registry August 1, 2022 October 2025
NCT05250349 Recruiting TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure September 1, 2021 September 1, 2027
NCT05143671 Recruiting Prospective Evaluation for Hybrid Cardiac Procedures May 13, 2021 May 12, 2025
NCT04973579 Recruiting Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients May 1, 2021 May 1, 2027
NCT04063709 Recruiting N/A Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk July 17, 2019 July 16, 2024
NCT04947046 Recruiting Carotid Stenosis Management During COVID-19 Era - Pilot Study March 11, 2020 March 1, 2026
NCT02089217 Recruiting N/A Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial December 9, 2014 February 2026
NCT04758650 Recruiting Phase 2 Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis January 26, 2021 January 26, 2025
NCT00106938 Terminated N/A Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I) April 2005 March 2013
NCT01968226 Terminated Phase 2 TRACER RGD-K5 Carotid Plaque Imaging Study November 2013 June 2016
NCT01602471 Terminated Phase 2 [F-18] RGD-K5 Positron Emission Tomography (PET) in Participants With Carotid Artery Stenosis May 2012 March 2013
NCT01599195 Terminated Use of Amplified Sound Signal to Identify Presence of Carotid and Femoral Stenosis April 2010 January 2017
NCT03755362 Terminated N/A Dental Carotid Cognitive Study April 8, 2019 February 25, 2021
NCT04180826 Terminated STAND: iSchemic sTroke evAluated at Bed Side With ultrasouND January 15, 2019 March 3, 2021
NCT00742612 Terminated Phase 2 Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy February 2009 April 2010
NCT00670202 Terminated Phase 2 Rho Kinase (ROCK) Inhibition in Carotid Atherosclerosis March 13, 2008 January 20, 2011
NCT00478673 Terminated Phase 4 Post-Approval Study of the NexStent Carotid Stent System and the FilterWire EZ Embolic Protection System: SONOMA May 2007 July 2009
NCT00395785 Terminated Phase 2/Phase 3 Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting November 2006 June 2007
NCT00904254 Unknown status Phase 2 The Use of Anti-CD4 mAb-Fragment for Imaging of Local Inflammation in Patients With Carotid Artery Stenosis January 2015 January 2016
NCT01210937 Unknown status Phase 4 Early Warning and Optimization Strategy in Carotid Endarterectomy January 2010 December 2014
NCT04821700 Unknown status Atrial Fibrillation and Carotid Atherosclerosis in Ischemic Stroke Patients-(AFCAS) March 20, 2020 April 5, 2021
NCT02133989 Unknown status Phase 3 Clopidogrel Resistance and Embolism in Carotid Artery Stenting June 2014 December 2017
NCT01994187 Unknown status Revascularization of Extracranial Carotid Artery Stenosis July 2013 June 2015
NCT02915328 Unknown status N/A Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery Stenting. A Randomized Study Comparing Carotid Wallstent vs Roadsaver® Stent and Distal vs Proximal Protection. April 2016 April 2018
NCT01106573 Unknown status Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery? June 2010 May 2013
NCT04327492 Unknown status Hemathologic and Imagiologic Predictors of Stroke During Carotid Endarterectomy With Regional Anesthesia April 1, 2020 December 31, 2022
NCT04470687 Unknown status N/A Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization March 17, 2021 March 17, 2022
NCT00883402 Unknown status N/A Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients January 2008 December 2020
NCT01272843 Unknown status Physiological Magnetic Resonance Imaging (MRI) to Improve Carotid Endarterectomy Outcomes February 2011 January 2015
NCT04162587 Unknown status Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke May 1, 2019 August 1, 2020
NCT04091074 Unknown status Phase 1 Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting January 1, 2022 December 1, 2022
NCT04057183 Unknown status Noninvasive Evaluation for Carotid Artery Stenosis: The Carotid Stenotic Scan July 1, 2019 June 30, 2020
NCT01273350 Unknown status N/A A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Bivalirudin) October 2004 December 2017
NCT05296876 Unknown status SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy April 1, 2022 November 30, 2023
NCT01451294 Unknown status N/A Effect of Blood Pressure on rSO2 in Carotid Endarterectomy (CEA) November 2011 March 2012
NCT00131001 Unknown status N/A CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis April 2001
NCT03929354 Unknown status N/A Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis June 1, 2018 September 1, 2022
NCT03840265 Unknown status N/A Evaluation of Cerebrovascular Events in Patients With Occlusive Carotid Artery Disorders February 6, 2019 November 30, 2022
NCT03757507 Unknown status N/A Investigation of Plaque Instability Using Bevacizumab-800CW and MSOT April 10, 2019 March 1, 2020
NCT03737175 Unknown status N/A Endarterectomy vs Stenting in Chinese Asymptomatic Carotid Stenosis Patients March 30, 2018 April 1, 2021
NCT02448355 Unknown status N/A Ocular Effects of Carotid Endarterectomy March 2016 December 2017
NCT03631381 Unknown status Retrospective Study of Carotid Surgery in Dijon September 4, 2017 December 2019
NCT01572623 Unknown status Phase 4 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting July 2011 September 2012
NCT03419767 Unknown status Phase 4 Insulin Resistance in Patients After Carotid Revascularization August 1, 2017 June 1, 2018
NCT03303430 Unknown status Microembolisation After Carotid Revascularisation March 30, 2017 March 30, 2019
NCT03283306 Unknown status Prognostic Value of Carotid CEUS in Acute Ischemic Stroke Patients August 9, 2017 September 30, 2020
NCT01799070 Unknown status Accuracy of TCD Monitoring in Predicting Cerebral Hyperperfusion Syndrome After Carotid Endarterectomy March 2013 December 2014
NCT00178451 Withdrawn Phase 1/Phase 2 Stroke Prevention With Abciximab in Carotid Endarterectomy
NCT04872127 Withdrawn N/A Distal Versus Proximal Protection on Cerebral Microembolization During High-risk Carotid Artery Stenting May 1, 2021 February 1, 2024
NCT00401921 Withdrawn Phase 2 A Study of the Effects of Minocycline on Cognitive Function After Carotid Endarterectomy October 2006 June 2010
NCT00315562 Withdrawn Phase 1 Study of Early Versus Delayed Carotid Endarterectomy (CEA) for Small to Medium-sized Ischemic Stroke Caused by High-grade Carotid Stenosis April 2006 March 2007
NCT01531868 Withdrawn N/A Alternative Sensory Presentation Formats in Asymptomatic Carotid Stenosis February 2012 May 2012
NCT00580580 Withdrawn N/A Detection of Coronary Stenosis With Intravenous Microbubbles February 2012 March 2014
Disase is a (Disease Ontology)
DOID:3407
Cross Reference ID (Disease Ontology)
MESH:D016893
Cross Reference ID (Disease Ontology)
NCI:C95804
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:195181000
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0007282
Exact Synonym (Disease Ontology)
Carotid artery stenosis
Exact Synonym (Disease Ontology)
Stenosis, carotid artery
MeSH unique ID (MeSH (Medical Subject Headings))
D016893