Idiopathic Pulmonary Fibrosis

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Disease name
Idiopathic Pulmonary Fibrosis
Disease ID
Description
Disease area statistics
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NCT ID Status Phase Summary Start date Completion date
NCT05313672 Active, not recruiting Inspiratory Effort and Respiratory Mechanics in Spontaneously Breathing Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Matched Control Study August 1, 2016 August 1, 2026
NCT02951416 Active, not recruiting Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank September 2009 January 2040
NCT02755441 Active, not recruiting Pulmonary Fibrosis Biomarker Cohort - a Prospective Cohort of Incident Patients With IPF April 2016 December 2028
NCT05185089 Active, not recruiting Phase 2 Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis August 1, 2022 June 2024
NCT04643769 Active, not recruiting Phase 1 Evaluation of Oral ORIN1001 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) February 9, 2021 December 30, 2024
NCT05032066 Active, not recruiting Phase 2 A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis August 25, 2021 July 2025
NCT02772549 Active, not recruiting Early Diagnosis of Pulmonary Fibrosis - Diagnostic Delay March 2016 December 2028
NCT04300920 Active, not recruiting Phase 3 Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial December 17, 2020 December 31, 2025
NCT03457935 Active, not recruiting Detection of Early Idiopathic Pulmonary Fibrosis April 10, 2018 December 31, 2024
NCT04572958 Active, not recruiting Changes in iOS in IPF November 6, 2020 May 2027
NCT02407431 Active, not recruiting PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort March 2015 July 2025
NCT05513950 Active, not recruiting Phase 1 A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF January 25, 2023 June 25, 2024
NCT05497284 Active, not recruiting Phase 2 To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF November 10, 2022 November 22, 2024
NCT04312594 Active, not recruiting Phase 2 Study of Jaktinib Hydrochloride Tablets in Participants With Idiopathic Pulmonary Fibrosis September 8, 2020 December 31, 2024
NCT05028894 Active, not recruiting 23andMe IPF Research Study June 5, 2020 December 1, 2023
NCT03747627 Active, not recruiting BPF Genetics of ILD Study January 19, 2019 January 1, 2028
NCT04071769 Active, not recruiting Phase 2 Genentech Xenon MRI Idiopathic Pulmonary Fibrosis August 3, 2020 August 30, 2024
NCT05321420 Active, not recruiting Phase 2 LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF) July 29, 2022 August 2025
NCT04614441 Active, not recruiting NICEFIT-ON: A Study Under Routine Clinical Practice in Taiwan to Observe the Long-term Outcome of People With Certain Types of Lung Disease (PF-ILD, SSc-ILD, IPF) Who Start Treatment With Nintedanib December 25, 2020 July 13, 2025
NCT05321069 Active, not recruiting Phase 3 A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) September 19, 2022 November 15, 2024
NCT05984992 Active, not recruiting Phase 1 The First-in-human Study of SRN-001 in Healthy Participants September 8, 2023 August 15, 2024
NCT02141087 Approved for marketing Expanded Access Program (EAP): Allow Patients in the US With Idiopathic Pulmonary Fibrosis Access to Pirfenidone
NCT02171156 Approved for marketing Expanded Access Program of Nintedanib in Patients With Idiopathic Pulmonary Fibrosis (EAP)
NCT00692796 Completed N/A Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis April 2008 March 2010
NCT00705133 Completed Phase 2 Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension July 2008 April 2011
NCT06135363 Completed Phase 1 Safety, Tolerability and Pharmacokinetic Study of SC1011 in Healthy Subjects August 11, 2022 January 14, 2023
NCT00815711 Completed Idiopathic Pulmonary Fibrosis Registry for Future Studies December 1, 2008 June 10, 2015
NCT00903331 Completed Phase 2 Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study May 2009 August 2011
NCT01071707 Completed Correlating Outcomes With Biochemical Markers to Estimate Time-progression in Idiopathic Pulmonary Fibrosis (IPF) December 2009 August 2012
NCT00074698 Completed Phase 1 Safety and Tolerability Study of FG-3019 in Participants With Idiopathic Pulmonary Fibrosis December 8, 2003 May 2004
NCT01107028 Completed Beneficial Effects of Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis February 2010 October 2014
NCT01110694 Completed Prospective Observation of Fibrosis in the Lung Clinical Endpoints Study September 2010 September 2018
NCT01118221 Completed N/A Rehabilitation of Idiopathic Pulmonary Fibrosis (IPF) Patients October 2010 September 2013
NCT01134822 Completed Prospective Study of Fibrosis In the Lung Endpoints (PROFILE - Central England) July 2010 September 5, 2017
NCT01136174 Completed Phase 2 Safety and PK Study of BIBF 1120 in Japanese Patients With IPF May 2010
NCT01150591 Completed Microaspiration in Pulmonary Fibrosis December 2009 June 2015
NCT01199887 Completed Phase 1 Trial Of IW001 in Patients With Idiopathic Pulmonary Fibrosis September 2010 October 2012
NCT01214187 Completed Phase 2 Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis July 2011 April 2015
NCT01254409 Completed Phase 1 A Phase 1b Study of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF) March 29, 2011 July 2, 2012
NCT01262001 Completed Phase 2 Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary Fibrosis March 2011 June 21, 2017
NCT01265888 Completed Phase 2 Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. March 2011 September 2016
NCT05976217 Completed Early Phase 1 Safety and Efficacy of Venetoclax in Idiopathic Pulmonary Fibrosis October 1, 2023 March 20, 2024
NCT05870956 Completed Burden of Nintedanib Non-adherence Among Idiopathic Pulmonary Fibrosis (IPF) Patients May 16, 2023 June 30, 2023
NCT01362231 Completed Phase 1 A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis December 2010 December 2012
NCT01366209 Completed Phase 3 Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) June 2011 February 2014
NCT05817240 Completed Phase 1 A Drug-Drug Interaction Study of ENV-101 (Taladegib) on Nintedanib Pharmacokinetics in Healthy Subjects May 3, 2023 June 21, 2023
NCT01385644 Completed Phase 1 A Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis October 2010 May 2013
NCT01457261 Completed Phase 1 IPF Drug Deposition Study April 2012 November 2014
NCT01462006 Completed N/A Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF) October 2011 March 2016
NCT05784207 Completed An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors June 1, 2017 December 30, 2021
NCT05779007 Completed Dose Reduction and Discontinuation With Anti-Fibrotic Medications April 18, 2023 July 14, 2023
NCT01529853 Completed Phase 1/Phase 2 To Evaluate the Effect of Different Doses of SAR156597 Given to Patients With Idiopathic Pulmonary Fibrosis (IPF) January 2012 October 2013
NCT01619085 Completed Phase 3 Extension Trial of the Long Term Safety of BIBF 1120 in Patients With Idiopathic Pulmonary Fibrosis June 6, 2012 February 1, 2021
NCT05657184 Completed Phase 1/Phase 2 Treatment of Idiopathic Pulmonary Fibrosis(IPF) by REGEND001 July 19, 2021 June 9, 2023
NCT01637831 Completed N/A CPAP Therapy in Patients With Idiopathic Pulmonary Fibrosis and Sleep Apnea March 2010 September 2011
NCT01695408 Completed Investigating Significant Health Trends in Idiopathic Pulmonary Fibrosis October 2012 December 31, 2021
NCT05621252 Completed Phase 2 Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809) July 13, 2022 January 8, 2024
NCT01725139 Completed Phase 1 A Proof of Mechanism Study With GSK2126458 in Patients With Idiopathic Pulmonary Fibrosis (IPF) March 8, 2013 July 12, 2016
NCT01766817 Completed Phase 2 Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis January 31, 2013 February 29, 2016
NCT05428150 Completed Phase 1 Randomized, Crossover, Multi-Dose Pharmacokinetics of EXCL-100 Pirfenidone-Sustained Release Tablet and Esbriet in Healthy Volunteers August 8, 2022 September 25, 2022
NCT01772667 Completed N/A Long Term Effects of an Inpatient Pulmonary Rehabilitation Program in Patients With Pulmonary Fibrosis October 2013 October 2016
NCT01777373 Completed Conducting Airways in Lung Fibrosis (VACFI) August 2012 February 2015
NCT05427253 Completed Phase 1 First-in-human Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of C106 in Healthy Subjects June 15, 2022 June 22, 2023
NCT01817686 Completed N/A Study of Default Options in Advance Directives March 2013 June 2015
NCT05383131 Completed Phase 1 To Evaluate Drug-drug Interactions Between HEC585 and Pirfenidone or Nintedanib in Healthy Volunteers June 23, 2021 November 30, 2021
NCT01872689 Completed Phase 2 A Study of Lebrikizumab in Participants With Idiopathic Pulmonary Fibrosis (IPF) October 13, 2013 November 6, 2017
NCT01874223 Completed Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With IPF June 2013 November 4, 2018
NCT01890265 Completed Phase 2 Evaluate the Safety and Efficacy of FG-3019 (Pamrevlumab) in Participants With Idiopathic Pulmonary Fibrosis (IPF) July 30, 2013 November 16, 2017
NCT01919827 Completed Phase 1 Study of Autologous Mesenchymal Stem Cells to Treat Idiopathic Pulmonary Fibrosis March 2013 May 1, 2018
NCT01979952 Completed Phase 3 Nintedanib Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF) November 26, 2013 October 27, 2016
NCT01982968 Completed N/A Treatment of IPF With Laparoscopic Anti-Reflux Surgery December 2013 November 2017
NCT02009293 Completed The Effect of Pirfenidone on Cough in Patients With Idiopathic Pulmonary Fibrosis December 2013 December 2016
NCT02019641 Completed N/A The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease May 23, 2015 May 24, 2023
NCT02036580 Completed Phase 2 D2212C00002 J-Phase II Study January 2014 November 2015
NCT02036970 Completed Phase 2 Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT May 31, 2014 May 16, 2018
NCT02048644 Completed Phase 2 Effect of Fostair® on Biomarkers of Platelet Adhesion in Idiopathic Pulmonary Fibrosis March 2014 May 2015
NCT05353556 Completed N/A Effects of Home-based Inspiratory Muscle Training in Patients With IPF February 21, 2022 May 30, 2022
NCT02055456 Completed Phase 1/Phase 2 Nandrolone Decanoate in the Treatment of Telomeropathies February 1, 2014 February 1, 2017
NCT02058602 Completed Phase 1 Inhalation Profiling of Idiopathic Pulmonary Fibrosis (IPF) Patients December 3, 2013 July 11, 2016
NCT02085018 Completed Phase 2 Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF) March 28, 2014 September 27, 2016
NCT02136992 Completed Phase 2 Clinical Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis December 2011 December 2013
NCT02173145 Completed N/A Azithromycin in Idiopathic Pulmonary Fibrosis August 19, 2014 August 16, 2019
NCT04016168 Completed Idiopathic Pulmonary Fibrosis and Serum Bank October 22, 2014 December 28, 2022
NCT04396756 Completed Phase 2 Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis March 3, 2020 February 15, 2023
NCT04030026 Completed Phase 2 A Study of Nalbuphine (Extended Release) ER in Idiopathic Pulmonary Fibrosis (IPF) for Treatment of Cough August 8, 2019 May 27, 2022
NCT04031690 Completed Health and Quality of Life Assessment Project for Caregivers of Idiopathic Pulmonary Fibrosis Patients October 14, 2019 December 15, 2021
NCT04072315 Completed Phase 2 Phase 2a Evaluation of PLN-74809 on αvβ6 Receptor Occupancy Using PET Imaging in Participants With IPF/ February 13, 2020 July 5, 2022
NCT00287716 Completed Phase 3 Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis July 14, 2006 November 10, 2008
NCT04177251 Completed Cardiovascular Fibrosis in Idiopathic Pulmonary Fibrosis October 21, 2019 October 15, 2022
NCT04187079 Completed Immunopathologic Profiles and Blood Biomarkers in Patients With IPF September 18, 2017 July 27, 2021
NCT00287729 Completed Phase 3 Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis April 2006 November 2008
NCT04318704 Completed Phase 2 Efficacy, Safety and Tolerability of NP-120 on Idiopathic Pulmonary Fibrosis and Its Associated Cough July 29, 2020 May 10, 2022
NCT04233814 Completed Phase 1 Safety, Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects January 20, 2020 December 23, 2021
NCT04316780 Completed Impact of Pre-transplant Anti-fibrotic Therapy for IPF Upon Lung Transplant Outcomes April 15, 2019 March 1, 2020
NCT00047658 Completed Phase 2 A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) November 2001 May 2003
NCT00391443 Completed Phase 3 BUILD 3: Bosentan Use in Interstitial Lung Disease February 2007 July 2010
NCT00453713 Completed Race, Ethnicity, and Diffuse Parenchymal Lung Disease July 2006 August 2013
NCT00463983 Completed Phase 1/Phase 2 Treatment of Idiopathic Pulmonary Fibrosis With Long Acting Octreotide October 2006 January 2012
NCT00071461 Completed Phase 2/Phase 3 Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis August 2003 May 2010
NCT00512967 Completed The Occurence of Inflammation and Oxidative Stress in Lung Diseases September 2005 June 2006
NCT00532233 Completed Phase 2 SD, IL-13 Production Rate in IPF September 2007 June 2009
NCT00540475 Completed Pennsylvania Idiopathic Pulmonary Fibrosis Research Registry September 2007 July 2018
NCT00600028 Completed Phase 3 Treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis With Thalidomide December 2007 September 2011
NCT00631475 Completed Phase 3 Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 April 2008 May 2010
NCT00662038 Completed Phase 3 Open-Label Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) August 2008 February 2016
NCT04525547 Completed Safety and Effectiveness of Nintedanib in Korean Patients January 13, 2021 August 18, 2022
NCT03725852 Completed Phase 2 A Clinical Study to Test How Effective and Safe GLPG1205 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) September 27, 2018 August 14, 2020
NCT03727802 Completed Phase 1 Safety, Tolerability, and Pharmacokinetic Study of TRK-250 for Patients With Idiopathic Pulmonary Fibrosis November 28, 2018 April 1, 2022
NCT03732859 Completed PROOF-Registry New and Extended Belgium -Luxembourg January 9, 2018 January 9, 2022
NCT04512170 Completed Phase 1 Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC585 in Healthy Male and Female Subjects July 13, 2020 August 23, 2021
NCT04481074 Completed N/A Inspiratory Muscle Training in Patients With Interstitial Lung Disease July 30, 2020 April 30, 2021
NCT03761082 Completed Post Marketing Surveillance of PIRESPA® TAB 200mg (Pirfenidone) for Evaluating the Safety and Efficacy July 2014 April 2017
NCT03770845 Completed Nutritional Assessment in Idiopathic Pulmonary Fibrosis December 10, 2018 September 1, 2021
NCT04430491 Completed To Evaluate the Use of Radiomics to Classify Between Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease January 1, 2005 July 1, 2017
NCT03830125 Completed Phase 1 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BBT-877 in Healthy Subjects February 13, 2019 November 24, 2019
NCT03890250 Completed N/A Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis March 20, 2019 January 1, 2024
NCT03898284 Completed Impulse Oscillometry for Prognostication in Idiopathic Pulmonary Fibrosis April 23, 2019 September 27, 2021
NCT00262405 Completed Phase 2 Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis January 2001 May 2007
NCT03928847 Completed Early Phase 1 Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis. December 1, 2017 May 31, 2019
NCT03944928 Completed ThOracic Ultrasound in Idiopathic Pulmonary Fibrosis Evolution June 11, 2019 September 9, 2021
NCT04429516 Completed Phase 3 Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough December 17, 2020 March 21, 2023
NCT04419506 Completed Phase 2 A Study to Test How Taking BI 1015550 for 12 Weeks Affects Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) July 28, 2020 October 15, 2021
NCT03958071 Completed A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking February 1, 2019 May 31, 2019
NCT03979430 Completed N/A Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study September 7, 2018 December 31, 2020
NCT03979703 Completed N/A Yoga in Patients With Fibrosing Interstitial Lung Diseases December 1, 2018 May 31, 2020
NCT03981406 Completed N/A Palliative Care and Quality of Life in Idiopathic Pulmonary Fibrosis September 15, 2017 March 1, 2019
NCT02248064 Completed N/A Auto-titrating Oxygen in Chronic Respiratory Failure July 2014 November 2015
NCT02257177 Completed Phase 1/Phase 2 RCT (Randomized Control Trial) of TD139 vs Placebo in HV's (Human Volunteers) and IPF Patients September 2014 December 2016
NCT02267655 Completed Phase 1 3 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPF May 2015 June 28, 2017
NCT02268981 Completed N/A Effects of an Oxymizer® During Daytime in Patients With Pulmonary Fibrosis (IPF) September 2014 September 2015
NCT02315586 Completed Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis January 28, 2015 February 23, 2022
NCT02345070 Completed Phase 2 Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis May 1, 2015 August 14, 2017
NCT05173571 Completed N/A Homecare Integral Support Program for IPF Patients July 1, 2018 December 12, 2021
NCT02436278 Completed The Predictive Ability of 4MGS in IPF March 2015 October 20, 2017
NCT02437448 Completed Breath Analysis in Lung Fibrosis June 2015 December 2018
NCT02445157 Completed Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis February 2015 August 2015
NCT02460588 Completed Phase 3 Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis December 2015 July 2019
NCT02477709 Completed Phase 2 A Study to Assess the Tolerability of a Single Dose of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic Pulmonary Fibrosis (IPF) July 20, 2015 August 21, 2015
NCT02478268 Completed Phase 1 Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis May 2015 September 26, 2020
NCT05154240 Completed Phase 1 A Phase 1, Evaluate the Safety, Tolerability, and Pharmacokinetics of INS018_055 in Healthy Subjects February 21, 2022 December 2, 2022
NCT02502097 Completed Phase 2 A Study of Gefapixant (AF-219/MK-7264) in Participants With Idiopathic Pulmonary Fibrosis (IPF) With Persistent Cough (MK-7264-016) August 26, 2015 July 14, 2016
NCT02503657 Completed Phase 2 Safety and Tolerability Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF) March 9, 2016 March 15, 2022
NCT02530736 Completed Responsiveness and MID of 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis February 2015 October 18, 2017
NCT02550873 Completed Phase 2 A Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) September 1, 2015 May 2, 2017
NCT00047645 Completed Phase 3 A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) April 2000 December 2002
NCT02552849 Completed Observational Study to Evaluate Disease Course and Outcomes in Patients Treated With Esbriet (Pirfenidone) for Idiopathic Pulmonary Fibrosis (IPF) in Canada April 25, 2013 August 15, 2017
NCT02579603 Completed Phase 4 Safety, Tolerability and PK of Nintedanib in Combination With Pirfenidone in IPF October 16, 2015 January 31, 2017
NCT02594839 Completed Phase 1/Phase 2 Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Patients With Rapidly Progressive Interstitial Lung Disease February 2013 January 2018
NCT02598193 Completed Phase 4 Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF) January 14, 2016 May 16, 2017
NCT02600689 Completed N/A Home-Based Pulmonary Rehab for Patients With Pulmonary Fibrosis August 2015 March 16, 2018
NCT02606877 Completed Phase 4 A Study to Compare the Amount of Nintedanib and Pirfenidone in the Blood When Nintedanib and Pirfenidone Are Given Separately or in Combination April 19, 2016 March 22, 2017
NCT02607722 Completed All-Case Surveillance of Ofev in Patients With IPF in Japan August 31, 2015 May 2, 2023
NCT02612051 Completed Phase 1 First Time in Human (FTIH) Study of GSK3008348 in Healthy Volunteers and Idiopathic Pulmonary Fibrosis Patients December 4, 2015 June 2, 2016
NCT02622477 Completed Clinical Progression of Mild to Moderate Idiopathic Pulmonary Fibrosis (IPF) Under a Therapy With Esbriet® (Pirfenidone) June 2014 December 2016
NCT02630940 Completed Exhaled Breath Condensate Biomarkers and Cough in IPF January 2016 June 2016
NCT02648048 Completed Phase 1 A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis January 15, 2016 November 30, 2016
NCT02688647 Completed Phase 2 A 2-Part, Phase 2 Open-label and Crossover Study of Belumosudil for Treatment of Idiopathic Pulmonary Fibrosis May 26, 2016 April 13, 2021
NCT02699879 Completed Evaluation of Long-Term Safety of Pirfenidone (Esbriet) in Participants With Idiopathic Pulmonary Fibrosis (IPF) February 16, 2012 September 15, 2016
NCT02707640 Completed Phase 2 A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF) August 2013 February 2015
NCT02738801 Completed Phase 2 Study to Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of GLPG1690 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) March 2016 May 2, 2017
NCT02739165 Completed Phase 3 Clinical Study of ART-123 for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis May 2016 December 2018
NCT02745184 Completed Phase 1/Phase 2 Clinical Efficacy and Safety of Autologous Lung Stem Cell Transplantation in Patients With Idiopathic Pulmonary Fibrosis March 30, 2017 August 31, 2020
NCT05134727 Completed Phase 1 Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 Following Single and Multiple Ascending Doses in Healthy Participants November 18, 2021 March 31, 2023
NCT02788474 Completed Phase 4 Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment June 9, 2016 June 8, 2018
NCT02802345 Completed Phase 3 Efficacy and Safety of Nintedanib Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function Impairment June 30, 2016 April 13, 2018
NCT02803580 Completed IPF Italian Observational Study (FIBRONET) in Idiopathic Pulmonary Fibrosis November 17, 2015 May 15, 2018
NCT02818712 Completed Health-related Quality of Life and Comorbidities in Danish Patients With Idiopathic Pulmonary Fibrosis - a Nationwide Follow-up August 2016 June 2021
NCT05130970 Completed Phase 2 CSL312 Safety, Pharmacokinetics, and Pharmacodynamics in Idiopathic Pulmonary Fibrosis January 27, 2022 January 2, 2024
NCT05113654 Completed Sleep Disorders in Idiopathic Pulmonary Fibrosis April 26, 2016 June 7, 2019
NCT02846324 Completed Phase 2 Study to Evaluate the Safety and Tolerability of GBT440 Administered to Subjects With IPF June 2016 November 2017
NCT05095363 Completed N/A Palliative Care Planner (PCplanner) March 16, 2022 March 31, 2023
NCT02871401 Completed Phase 1 A Pilot Trial of Herpesvirus Treatment in Idiopathic Pulmonary Fibrosis (IPF) January 3, 2018 January 31, 2020
NCT02929017 Completed N/A Integrating Palliative Care for Patients With Idiopathic Pulmonary Fibrosis and Their Caregivers March 23, 2017 June 24, 2020
NCT02951429 Completed Phase 2 Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary Hypertension December 31, 2016 August 22, 2020
NCT03047031 Completed Post Marketing Surveillance of Nintedanib in Indian Patients With Idiopathic Pulmonary Fibrosis April 5, 2017 July 21, 2022
NCT05022784 Completed Adherence to Nintedanib Among Idiopathic Pulmonary Fibrosis Patients August 23, 2021 December 30, 2021
NCT03074149 Completed Investigating Idiopathic Pulmonary Fibrosis in Greece April 4, 2017 March 30, 2021
NCT03078426 Completed N/A Lung MRI in the Management of Idiopathic Pulmonary Fibrosis February 16, 2017 February 14, 2020
NCT03092102 Completed Phase 1 The Safety, Tolerability and Pharmacokinetic Study of HEC585 in Healthy Male and Female Subjects May 20, 2017 February 25, 2019
NCT03104322 Completed N/A Patient-reported Monitoring of Symptoms and Spirometry Via the patientMpower Platform in Idiopathic Pulmonary Fibrosis June 15, 2017 March 9, 2018
NCT03115619 Completed Quality of Life Study in Participants With IPF Under Pirfenidone Treatment April 18, 2017 January 10, 2020
NCT00080223 Completed Phase 2 Safety Study of Oral Pirfenidone in Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis August 31, 2003 April 30, 2015
NCT05022771 Completed Phase 1 A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015 October 14, 2021 August 18, 2022
NCT04986540 Completed Phase 1 A Trial of SHR - 1906 in Healthy Subjects August 10, 2021 September 7, 2022
NCT00105183 Completed Phase 3 EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection January 2005 January 2011
NCT03208933 Completed Phase 3 Open-label Study to Assess the Effectiveness of Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis (IPF). October 23, 2017 November 13, 2019
NCT03211507 Completed Idiopathic Pulmonary Fibrosis Job Exposures Study May 1, 2017 October 5, 2019
NCT04968574 Completed Phase 2 A Study Evaluating the Safety and Efficacy of ENV-101 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) August 26, 2021 November 30, 2023
NCT03222648 Completed N/A Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis September 22, 2017 August 8, 2023
NCT04931147 Completed Phase 1 A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers May 13, 2021 March 8, 2023
NCT03261037 Completed N/A A Study to Characterize the Disease Behavior of Idiopathic Pulmonary Fibrosis (IPF) and Interstitial Lung Disease (ILD) During the Peri-Diagnostic Period December 25, 2017 November 27, 2019
NCT03268915 Completed N/A Idiopathic Pulmonary Fibrosis (IPF) and the 3 Minutes Sit-to-stand Test February 9, 2017 December 9, 2018
NCT03281200 Completed Chart Review Study to Describe the Clinical Profile of Idiopathic Pulmonary Fibrosis (IPF) Patients Treated With Nintedanib (OFEV®) in Real-world Practice in Spain October 24, 2017 June 7, 2018
NCT04888728 Completed Phase 1 To Evaluate Drug-drug Interactions Between DWN12088 and Nebivolol or Paroxetine in Healthy Volunteers June 30, 2021 July 27, 2021
NCT03300583 Completed Toward Self-management in ILD June 1, 2018 December 30, 2020
NCT03326089 Completed N/A Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis June 1, 2017 August 28, 2023
NCT04888715 Completed Phase 1 To Evaluate Drug-drug Interactions Between DWN12088 and Pirfenidone or Nintedanib in Healthy Volunteers July 23, 2021 August 18, 2021
NCT03386994 Completed OASIS-IPF (Idiopathic Pulmonary Fibrosis) Study November 29, 2017 September 16, 2019
NCT03411876 Completed N/A Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis January 18, 2018 January 15, 2019
NCT03420235 Completed N/A Home Monitoring in Idiopathic Pulmonary Fibrosis; Improving Use of Anti-fibrotic Medication and Quality of Life January 9, 2018 August 26, 2019
NCT03422068 Completed Phase 1 This Study Tests Different Doses of BI 1015550 in Patients With Idiopathic Pulmonary Fibrosis (IPF). The Study Tests How BI 1015550 is Taken up by the Body and How Well it is Tolerated. March 16, 2018 July 10, 2019
NCT00125385 Completed Phase 1 Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) July 2005 September 2008
NCT04803617 Completed Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease January 23, 2017 June 23, 2017
NCT03499275 Completed N/A Muscle Stimulation in Advanced Idiopathic Pulmonary Fibrosis October 15, 2018 August 15, 2020
NCT00131274 Completed Phase 2/Phase 3 Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study April 2003 August 2007
NCT03502902 Completed Phase 1 The Safety, Tolerability and Pharmacokinetic Study of HEC68498 in Healthy Male and Female Subjects April 26, 2018 March 15, 2019
NCT03503188 Completed Phase 4 Digital Auscultation Test - IPF Data Collection March 28, 2018 January 3, 2019
NCT03538301 Completed Phase 2 JUNIPER: A Phase 2 Study to Evaluate the Safety, Biological Activity, and PK of ND-L02-s0201 in Subjects With IPF June 18, 2018 August 24, 2022
NCT04775277 Completed Outcome of Idiopathic Pulmonary Fibrosis With Pregnancy December 1, 2018 February 20, 2021
NCT04767815 Completed Phase 1 To Evaluate Food Effect on the PK and Safety After Oral DWN12088 Administration in Healthy Adult Volunteers March 22, 2021 June 4, 2021
NCT04720443 Completed Phase 1 A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects November 22, 2019 July 14, 2022
NCT03567785 Completed Supporting Adherence to Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis July 17, 2018 February 11, 2021
NCT03588260 Completed Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis July 20, 2018 December 30, 2023
NCT04586946 Completed FIBRotic Interstitial Lung Disease and Nocturnal OXygen December 17, 2018 May 30, 2021
NCT03641742 Completed Families-At-risk for Interstitial Lung Disease Study January 15, 2018 July 1, 2023
NCT04572971 Completed Reliability and Validity of iOS in IPF November 6, 2020 March 30, 2022
NCT04564664 Completed N/A High-flow Oxygen Therapy During Exercise in Idiopathic Pulmonary Fibrosis March 1, 2019 March 30, 2021
NCT00189176 Completed Phase 1/Phase 2 Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis March 2003 May 2006
NCT03710824 Completed Investigating Trends in Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (IPF) Under Treatment With Nintedanib February 28, 2019 February 22, 2023
NCT04533022 Completed Phase 2 Safety, Efficacy and Pharmacokinetics of C21 in Subjects With IPF November 13, 2020 March 30, 2024
NCT03711435 Completed Traditional Chinese Medicine(TCM) Syndrome Classification of Idiopathic Pulmonary Fibrosis(IPF) and Metabolomics October 20, 2018 February 5, 2020
NCT04016181 Enrolling by invitation The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study June 14, 2007 December 1, 2036
NCT04326036 Enrolling by invitation Early Phase 1 Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection March 25, 2020 January 31, 2024
NCT04896138 Enrolling by invitation University of Virginia Natural History Study August 28, 2018 August 31, 2035
NCT04905693 Enrolling by invitation Phase 3 Extension Study of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis September 6, 2022 June 2026
NCT02230982 No longer available Expanded Access Program of Nintedanib in Patients With Idiopathic Pulmonary Fibrosis
NCT05983471 Not yet recruiting Phase 2 Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF) November 2023 March 2025
NCT06238622 Not yet recruiting Phase 3 A Follow-up Study to Test Long-term Treatment With BI 1015550 in People With Pulmonary Fibrosis Who Took Part in a Previous Study With BI 1015550 July 1, 2024 May 5, 2027
NCT05988463 Not yet recruiting Phase 1 Open-Label Dose-Escalation Treatment Study of Patients With IPF February 1, 2024 November 1, 2024
NCT06325696 Not yet recruiting Phase 2 H01 in Adults With Interstitial Lung Disease (The SOLIS Study) June 23, 2024 December 31, 2025
NCT05842681 Not yet recruiting N/A Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis June 1, 2023 June 1, 2024
NCT06317285 Not yet recruiting Phase 2 A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF) April 1, 2024 March 19, 2026
NCT06335303 Not yet recruiting Phase 2 A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) July 24, 2024 July 21, 2026
NCT06323876 Not yet recruiting The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis May 2024 May 2029
NCT06422884 Not yet recruiting Phase 2 A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial) September 2024 June 2026
NCT06360094 Not yet recruiting Phase 2 A Study to Test Whether BI 1839100 Improves Cough in People With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis July 27, 2024 August 6, 2025
NCT05424887 Not yet recruiting Phase 2 A Study to Evaluate the Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary Fibrosis July 2022 October 2024
NCT06049004 Not yet recruiting Londrina Activities of Daily Living Protocol in Idiopathic Pulmonary Fibrosis Patients November 1, 2023 November 1, 2024
NCT05755308 Not yet recruiting N/A Faecal Microbiota Transplantation to Ameliorate Nintedanib-induced Diarrhea in Patients With Idiopathic Pulmonary Fibrosis October 2023 April 2026
NCT03800017 Not yet recruiting N/A Skeletal Muscle Function in Interstitial Lung Disease June 1, 2024 December 31, 2026
NCT06102083 Not yet recruiting Phase 2 A Clinical Trial on the Treatment of Idiopathic Pulmonary Fibrosis November 2, 2023 March 1, 2026
NCT06241560 Not yet recruiting Phase 2 A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood September 30, 2024 August 15, 2025
NCT06445686 Recruiting Ongoing Monitoring of Vital Signs in Patients With Idiopathic Pulmonary Fibrosis Before and After Acute Exacerbation. June 2024 February 2026
NCT00373841 Recruiting Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF) October 2005 July 2030
NCT00470327 Recruiting A Study of the Natural Progression of Interstitial Lung Disease (ILD) September 2005 December 2025
NCT01088217 Recruiting Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) July 2008 June 2025
NCT02551068 Recruiting N/A High Oxygen Delivery to Preserve Exercise Capacity in Idiopathic Pulmonary Fibrosis Patients Treated With Nintedanib December 2015 April 2025
NCT02632123 Recruiting Validation of the Risk Stratification Score in Idiopathic Pulmonary Fibrosis December 2015 December 2025
NCT03120481 Recruiting Controls for Respiratory Diseases April 10, 2017 February 28, 2037
NCT03183570 Recruiting Early Phase 1 Detection of Integrin avb6 in IPF, PSC, and COVID19 Using PET/CT November 8, 2017 April 14, 2025
NCT03437486 Recruiting Mechanisms of Familial Pulmonary Fibrosis January 1, 2009 April 30, 2025
NCT03500731 Recruiting Phase 1/Phase 2 Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure April 19, 2018 December 2026
NCT03692481 Recruiting N/A Evolution of Lung 18FDG Uptake in Patients With Idiopathic Pulmonary Fibrosis and Receiving Pirfenidone February 4, 2020 April 2024
NCT03836417 Recruiting Molecular Diagnosis of Idiopathic Interstitial Pneumonias: a Prospective Study June 28, 2019 June 30, 2025
NCT03865927 Recruiting Phase 2 GKT137831 in IPF Patients With Idiopathic Pulmonary Fibrosis September 7, 2020 January 1, 2025
NCT03901196 Recruiting Multi-elemental Imaging of Lung Tissues With LIBS (Laser-induced Breakdown Spectroscopy) January 22, 2020 January 22, 2025
NCT04160715 Recruiting Korean Idiopathic Pulmonary Fibrosis Registry January 2016 December 2026
NCT04187690 Recruiting N/A Jin-shui Huan-xian Granule in the Treatment of IPF September 1, 2020 July 30, 2023
NCT04263727 Recruiting A Study of Patients With Chronic Disease February 27, 2020 February 2035
NCT04268485 Recruiting Longitudinal Changes in Serum KL-6 in IPF February 1, 2021 December 30, 2024
NCT04362644 Recruiting Phase 1 Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis December 8, 2020 June 1, 2025
NCT04442711 Recruiting Cohort of IPF Patients Experiencing an Exacerbation June 13, 2020 December 31, 2028
NCT04540770 Recruiting Phase 1 A Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Immunogenicity of HuL001 August 31, 2021 December 31, 2023
NCT04619199 Recruiting N/A Influence of Socioeconomic and Environmental Factors on the Natural History of Idiopathic Pulmonary Fibrosis April 1, 2021 April 1, 2025
NCT04708782 Recruiting Phase 3 Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis June 1, 2021 June 2025
NCT04838275 Recruiting N/A IPF mHealth Exercise April 1, 2021 December 31, 2023
NCT04965298 Recruiting Phase 3 Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole June 16, 2021 February 28, 2025
NCT05016817 Recruiting Phase 1 Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IPF July 3, 2022 September 2025
NCT05042219 Recruiting Effects of Pulmonary Diseases and Their Treatment on Cardiac Function June 1, 2022 September 14, 2024
NCT05052229 Recruiting Early Phase 1 Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF). April 21, 2022 February 28, 2025
NCT05060822 Recruiting Phase 2 Phase ll Study of HEC585 in Patients With IPF June 30, 2021 May 11, 2025
NCT05098717 Recruiting End-expiratory Trans-pulmonary Pressure Guided PEEP Titration in Patients With Pulmonary Fibrosis and UIP Pattern Undergoing Mechanical Ventilation February 8, 2023 January 1, 2027
NCT05195918 Recruiting Phase 1 Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients August 24, 2023 March 31, 2025
NCT05241275 Recruiting Phase 2 Xenon MRI and Progressive ILD July 19, 2022 June 1, 2026
NCT05255991 Recruiting Phase 3 Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis October 4, 2022 June 2025
NCT05331729 Recruiting Phase 1 Evaluation of the Value of 18F-Fluoromisonidazole (18F-FMISO) Positron Emission Tomography Hypoxia Imaging in Idiopathic Pulmonary Fibrosis March 20, 2023 May 2026
NCT05359965 Recruiting N/A Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF October 1, 2019 March 1, 2025
NCT05366387 Recruiting N/A Effect of Intrapulmonary Percussion Ventilation on Deposition of Inhaled Aerosols in Idiopathic Pulmonary Fibrosis November 23, 2022 May 2024
NCT05382572 Recruiting Pulmonary Fibrosis Foundation Community Registry July 11, 2022 July 1, 2025
NCT05389215 Recruiting Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF July 29, 2022 December 19, 2025
NCT05392881 Recruiting Interstitial Lung Disease Research Unit Biobank August 9, 2021 March 1, 2032
NCT05449431 Recruiting N/A Comparison of the 1-min Sit-to-Stand Test to the 6-minute Walk Test in the Respiratory Functional Assessment of Pulmonary Fibrosis August 8, 2022 December 5, 2024
NCT05468502 Recruiting Phase 1 Phase I/IIa Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Idiopathic Pulmonary Fibrosis (IPF) October 10, 2022 August 2025
NCT05483907 Recruiting Phase 2 To Evaluate the Efficacy, Safety, and Tolerability of BBT-877 in Patients With IPF April 12, 2023 December 31, 2024
NCT05515627 Recruiting Phase 1 Atezolizumab for Idiopathic Pulmonary Fibrosis February 15, 2023 April 30, 2026
NCT05537025 Recruiting Phase 1/Phase 2 Study of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients With Idiopathic Pulmonary Fibrosis January 30, 2023 March 2025
NCT05571059 Recruiting Phase 2 Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF) January 31, 2024 January 2026
NCT05671835 Recruiting Phase 2 Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis May 15, 2023 March 2025
NCT05722964 Recruiting Phase 2 Study on Intravenous Injection of SHR-1906 in the Treatment of Idiopathic Pulmonary Fibrosis March 29, 2023 May 31, 2024
NCT05785624 Recruiting Phase 2 A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease May 26, 2023 August 10, 2027
NCT05863091 Recruiting N/A Respiratory Rate Validation Study - HiCardi+ Wearable Patch Device, Mezoo Co., Ltd. March 9, 2023 June 2023
NCT05883293 Recruiting Early Phase 1 Clinical Study of Allogeneic Adipovarian Active Protein in the Treatment of Severe Idiopathic Pulmonary Fibrosis June 1, 2023 December 31, 2024
NCT05912049 Recruiting Phase 1 A Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties and Immunogenicity of 9MW3811 in Healthy Subjects July 26, 2023 December 2023
NCT05951296 Recruiting Phase 2 A Study to Investigate Leramistat in Patients With IPF August 30, 2023 September 2024
NCT05954988 Recruiting Phase 1 A Study to Evaluate LTI-03 in Newly Diagnosed Idiopathic Pulmonary Fibrosis (IPF) Patients July 6, 2023 January 2024
NCT05964335 Recruiting Phase 2 Cough Reduction in IPF With Nalbuphine ER February 6, 2024 October 14, 2024
NCT05989698 Recruiting N/A C-mo System 1.0's Validation - Cough Monitoring December 11, 2023 June 11, 2025
NCT06003426 Recruiting Phase 3 A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis September 14, 2023 October 26, 2026
NCT06027372 Recruiting Heart Rate Variability and Nocturnal Blood Oxygen Saturation in Patients With Idiopathic Pulmonary Fibrosis May 21, 2020 June 30, 2024
NCT06037408 Recruiting Phase 3 The Effect of N115 on Coughing in IPF Patients August 15, 2023 August 31, 2024
NCT06081621 Recruiting Phase 2 A Clinical Study to Evaluate the Efficacy and Safety of REGEND001 Cell Therapy on Idiopathic Pulmonary Fibrosis (IPF) June 30, 2023 July 2025
NCT06097260 Recruiting Phase 2 Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis November 16, 2023 September 30, 2025
NCT06125327 Recruiting Phase 2/Phase 3 SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF) June 6, 2023 December 31, 2025
NCT06132256 Recruiting Phase 2 Study to Evaluate Axatilimab in Participants With Idiopathic Pulmonary Fibrosis (IPF) December 11, 2023 June 2025
NCT06189820 Recruiting Phase 2 Role of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung Diseases March 9, 2023 March 9, 2027
NCT06200714 Recruiting A Study Based on Medical Records in Spain That Looks at Diarrhoea Control in People With Pulmonary Fibrosis Who Are Taking Nintedanib April 30, 2024 April 30, 2025
NCT06230822 Recruiting Phase 1 Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF) February 2024 December 2026
NCT06265532 Recruiting Phase 1 Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect February 7, 2024 May 31, 2025
NCT06267183 Recruiting Early Phase 1 A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers. January 12, 2024 March 30, 2025
NCT06331624 Recruiting Phase 2 Biomarker Modulation and the Inhibition of NKT1 Cells by Oral GRI-0621 in Patients With IPF March 2024 January 2025
NCT00075998 Terminated Phase 3 The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) December 2003 May 2007
NCT02052297 Terminated Phase 1 A Validation and Dosimetry Study of GSK2634673F PET Ligand January 24, 2014 April 21, 2016
NCT03955146 Terminated Phase 3 Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF) June 18, 2019 August 28, 2023
NCT04419558 Terminated Phase 3 Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF) September 30, 2020 September 4, 2023
NCT03949530 Terminated Phase 1 A Study of Safety & Blood Levels of IDL-2965 in Healthy Subjects and Patients With a Special Type of Pulmonary Fibrosis April 16, 2019 March 29, 2020
NCT00957242 Terminated Phase 3 AntiCoagulant Effectiveness in Idiopathic Pulmonary Fibrosis October 2009 July 2011
NCT03480451 Terminated N/A Targeted Intervention for Patient Centered Outcome in Patients With Idiopathic Pulmonary Fibrosis September 12, 2017 February 1, 2019
NCT03744598 Terminated Self-monitoring of Spirometry & Symptoms Via patientMpower App in Idiopathic Pulmonary Fibrosis November 28, 2018 April 30, 2020
NCT03562247 Terminated N/A Telenursing and Remote Monitoring in Idiopathic Pulmonary Fibrosis (IPF) August 1, 2018 May 26, 2020
NCT03733444 Terminated Phase 3 A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care November 5, 2018 March 30, 2021
NCT03717012 Terminated Phase 4 Study of Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis (IPF) November 15, 2018 June 10, 2020
NCT03711162 Terminated Phase 3 A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care November 28, 2018 March 30, 2021
NCT00703339 Terminated Phase 2 Effects of Inhaled Treprostinil Sodium for the Treatment of Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis June 2008 December 2009
NCT01629667 Terminated Phase 2 A Phase 2, Randomized Dose-ranging Study to Evaluate the Efficacy of Tralokinumab in Adults With Idiopathic Pulmonary Fibrosis October 2012 January 2016
NCT04552899 Terminated Phase 3 A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis March 19, 2021 February 10, 2023
NCT03274544 Terminated N/A Clinical Trial of Chinese Herbal Medicine for Idiopathic Pulmonary Fibrosis (IPF) August 14, 2018 June 1, 2020
NCT02989168 Terminated Phase 2 Study to Evaluate the Effect of GBT440 Administered to Subjects With IPF on Supplemental Oxygen at Rest November 2016 October 23, 2017
NCT00768300 Terminated Phase 3 (ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF December 2008 February 2011
NCT03562416 Terminated Phase 2 Continuation of Nintedanib After Single Lung Transplantation in IPF Subjects July 5, 2019 December 21, 2021
NCT04594707 Terminated Phase 3 A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis August 30, 2021 February 10, 2023
NCT03573505 Terminated Phase 2 An Efficacy and Safety Study of BG00011 in Participants With Idiopathic Pulmonary Fibrosis September 24, 2018 November 14, 2019
NCT01841307 Terminated Phase 1 Cromolyn Detection of Silent Aspiration July 2015 September 2017
NCT03069989 Terminated Phase 1 Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging June 13, 2017 July 18, 2018
NCT01266135 Terminated Phase 2 Safety and Efficacy of QAX576 in Patients With Idiopathic Pulmonary Fibrosis (IPF) December 2010 April 2013
NCT00076635 Terminated Phase 3 An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF November 2003 April 2007
NCT01777737 Terminated Phase 3 Study to Test the Validity of the Treatment of Idiopathic Pulmonary Fibrosis With Cotrimoxazole November 25, 2013 November 5, 2015
NCT01769196 Terminated Phase 2 Study to Assess the Efficacy and Safety of Simtuzumab (GS-6624) in Adults With Idiopathic Pulmonary Fibrosis (IPF) January 31, 2013 February 23, 2016
NCT01203943 Terminated Phase 2 A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF) January 1, 2011 August 24, 2012
NCT01321996 Terminated Phase 4 68Ga-DOTA-NOC PET/CT in Patients With Idiopathic Pulmonary Fibrosis February 2009 December 2013
NCT00981747 Terminated Phase 2/Phase 3 Targeting Vascular Reactivity in Idiopathic Pulmonary Fibrosis September 2009 December 2016
NCT01759511 Terminated Phase 2 Long-Term Safety Study of GS-6624 in Adults With Idiopathic Pulmonary Fibrosis (IPF) October 18, 2012 February 19, 2016
NCT02821039 Terminated Turkish Thoracic Society Usual Interstitial Pneumonia Registry Study June 2016 July 8, 2019
NCT03142191 Terminated Phase 2 A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis July 26, 2017 December 24, 2021
NCT03287414 Terminated Phase 2 Study of Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of VAY736 in Patients With Idiopathic Pulmonary Fibrosis December 20, 2017 February 14, 2022
NCT02759120 Terminated Phase 3 CleanUP IPF for the Pulmonary Trials Cooperative March 22, 2017 March 16, 2020
NCT00879229 Terminated Phase 3 ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis July 2009 February 2011
NCT01499745 Unknown status N/A Exercise Training at Ambulatory Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis Patients January 2012 December 2013
NCT02848625 Unknown status N/A Yoga Effect on Quality of Life Study Among Patients With Idiopathic Pulmonary Fibrosis August 2016 April 2018
NCT01382368 Unknown status Phase 4 Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients September 2011 September 2013
NCT02827734 Unknown status Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD) October 2015 December 2020
NCT02485886 Unknown status Early Phase 1 68Ga-BMV101 PET/CT in Patients With Idiopathic Pulmonary Fibrosis January 2015 December 2017
NCT02397005 Unknown status Phase 1 Study of the Tolerability and Pharmacokinetic of ZL-2102 With an Investigation of Food Effect in Healthy Male Subjects March 2015 August 2019
NCT02176707 Unknown status Modelling of Quality Life, Clinical and Physiological Measures in Idiopathic Pulmonary Fibrosis June 2014 February 2017
NCT02135380 Unknown status Phase 1/Phase 2 Evaluate Safety and Efficacy of Intravenous Autologous ADMSc for Treatment of Idiopathic Pulmonary Fibrosis August 2014
NCT05373914 Unknown status Phase 2 RESPIRARE - Efficacy and Safety of Cudetaxestat in Patients With Idiopathic Pulmonary Fibrosis (IPF) May 31, 2022 March 31, 2024
NCT00518310 Unknown status N/A Azathioprine and Prednisone in the Treatment of Idiopathic Pulmonary Fibrosis May 2005 December 2008
NCT01809574 Unknown status The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease May 2013 March 2016
NCT01154998 Unknown status Case-Control Study of Fibrotic Interstitial Lung Disease (ILD) and Cardiac Disease / Interventions. July 2010 April 2011
NCT01738711 Unknown status N/A Does CBT Improve the Perception/Impact of Cough and Breathlessness in IPF Patients December 2012 February 2014
NCT04257630 Unknown status Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD February 6, 2020 March 31, 2022
NCT04197791 Unknown status N/A Effect of Core Stabilization Exercises and Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis December 10, 2019 December 2020
NCT04148157 Unknown status Quality of Life in IPF - Patient and Physician Perceptions September 23, 2019 July 1, 2020
NCT04019080 Unknown status Real-Life Use of Anti-fibrotic Drugs in Patients With Idiopathic Pulmonary Fibrosis in Sweden January 1, 2019 December 2021
NCT03813810 Unknown status Impact of Air Pollution on Chronic Respiratory Diseases January 25, 2019 December 2021
NCT03688334 Unknown status N/A Acute Effects of Oxygen Supplementation Among IPF Patients June 1, 2018 June 1, 2019
NCT03670576 Unknown status It's Not JUST Idiopathic Pulmonary Fibrosis Study November 11, 2018 November 11, 2022
NCT03666234 Unknown status Idiopathic Pulmonary Fibrosis Registry China Study July 1, 2018 June 30, 2023
NCT01714934 Unknown status The Role of Gastric Content Microaspirations in the Pathogenesis of Idiopathic Pulmonary Fibrosis January 2013 December 2014
NCT04693975 Unknown status Social Distancing During the COVID-19 Pandemic and People Living With Chronic Respiratory Diseases October 16, 2020 October 2022
NCT03560154 Unknown status N/A Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease January 2017 September 2020
NCT03548181 Unknown status Phase 2 Feasibility & Effect of a Tele-rehabilitation Program in Idiopathic Pulmonary Fibrosis (IPF) September 1, 2017 January 31, 2020
NCT00637065 Unknown status Phase 4 Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study April 2008 August 2010
NCT03360032 Unknown status Comparing Measurements Made in an Incremental Shuttle Walk Test and a Cardiopulmonary Exercise Test in Patients With IPF January 10, 2018 April 2020
NCT03229343 Unknown status N/A Impact of a Systematic Palliative Care on Quality of Life, in Advanced Idiopathic Pulmonary Fibrosis. December 4, 2017 February 2021
NCT03215147 Unknown status Prevalence and Impact on Quality of Life of Airway Disease in Patients With Idiopathic Pulmonary Fibrosis June 7, 2017 February 28, 2020
NCT03171870 Unknown status N/A Characteristics and Health Related Quality of Life in Idiopathic Pulmonary Fibrosis June 2017 June 2018
NCT02885961 Unknown status N/A The Coagulation Cascade in Idiopathic Pulmonary Fibrosis August 2016
NCT01504334 Unknown status Phase 2 Safety and Efficacy Study of Pirfenidone to Treat Idiopathic Pulmonary Fibrosis(IPF) January 2012 March 2013
NCT00203697 Unknown status Phase 3 Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study
NCT00625079 Withdrawn Phase 4 Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil February 2007 December 2009
NCT03258801 Withdrawn Pirfenidone as Bridging Therapy for Lung Transplant in Patients Suffering From Idiopathic Pulmonary Fibrosis October 29, 2018 December 2, 2019
NCT03591926 Withdrawn Phase 2 A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of SM04646 Inhalation Solution in Subjects With Idiopathic Pulmonary Fibrosis (IPF) January 1900 January 1900
NCT04677426 Withdrawn Phase 2 129Xe Gas Exchange Imaging in IPF and cHP: A Reliability Study May 1, 2022 August 1, 2022
NCT02168530 Withdrawn Phase 2 A Study of Oral Vismodegib for the Treatment of Idiopathic Pulmonary Fibrosis (IPF) October 2014 January 2017
NCT04541875 Withdrawn Medication Adherence and Non-adherence in Adults With Rare Disease January 2021 September 2022
NCT04494334 Withdrawn Development of Airway Absorption Sampling Methods January 1, 2022 January 1, 2022
NCT00625469 Withdrawn Phase 4 Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan October 2007 December 2009
NCT01346930 Withdrawn Phase 2 Safety and Tolerability Study of Macitentan in Patients With Idiopathic Pulmonary Fibrosis July 2011 August 2016
NCT00212511 Withdrawn Evaluation of Patients With Idiopathic Pulmonary Fibrosis (IPF) Through an IPF Registry November 2004 January 2018
NCT02187393 Withdrawn Determining in Vitro Properties of Epithelial Cells From Individuals With Genetic Variants Associated With Idiopathic Pulmonary Fibrosis July 2015 November 2015
NCT01524068 Withdrawn Phase 2 A MultiCenter Study of Combined PEX, Rituximab, and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations September 2012 June 2016
NCT04244825 Withdrawn Phase 2 Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF December 15, 2019 November 5, 2020
OrphaNumber from OrphaNet (Orphanet)
2032
MedGen concept unique identifier (MedGen Concept name)
C0085786
MedGen unique identifier (MedGen Concept name)
39340
MeSH unique ID (MeSH (Medical Subject Headings))
D054990