Fibrosis
Information
- Disease name
- Fibrosis
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04998500 | Active, not recruiting | N/A | Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis | August 1, 2021 | December 31, 2023 |
| NCT05685823 | Active, not recruiting | The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle | October 1, 2019 | October 31, 2023 | |
| NCT03612531 | Active, not recruiting | N/A | Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors | August 6, 2018 | December 31, 2025 |
| NCT05075785 | Active, not recruiting | Covid-19 Respiratory Sequelae French Cohort | October 7, 2021 | May 2024 | |
| NCT05920226 | Active, not recruiting | Myocardial Fibrosis in Patients With Permanent Pacemakers | July 1, 2023 | July 1, 2028 | |
| NCT02384733 | Active, not recruiting | N/A | Hypofractionated Loco-regional Adjuvant Radiation Therapy of Breast Cancer Combined With a Simultaneous Integrated Boost | March 2015 | July 1, 2032 |
| NCT05716919 | Active, not recruiting | Phase 1 | Multiple Ascending Dose Study of CG200745 'Ivaltinostat' Oral Capsule | March 9, 2023 | December 2023 |
| NCT00455767 | Completed | Phase 2 | Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients | July 2006 | September 2007 |
| NCT00583700 | Completed | Phase 2 | Trental & Vitamin E for Radiation-Induced Fibrosis | February 2003 | June 2012 |
| NCT00629603 | Completed | N/A | Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease | January 2007 | September 2009 |
| NCT00655018 | Completed | Phase 2/Phase 3 | Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) | January 2003 | October 2006 |
| NCT00707421 | Completed | Phase 3 | Usefulness of Topical Non-Steroidal Anti-Inflammatory Drugs or Steroids Before Trabeculectomy and Clinical Outcomes | July 2005 | May 2009 |
| NCT00744939 | Completed | Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist | November 2008 | November 2013 | |
| NCT00828737 | Completed | Phase 4 | Safety of Gadovist in Renally Impaired Patients | December 2008 | January 2015 |
| NCT01040104 | Completed | Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals | July 2009 | ||
| NCT01166594 | Completed | Phase 4 | Use of Bevacizumab in Trabeculectomy Surgery | June 2010 | December 2013 |
| NCT01187173 | Completed | The Fibrosis-Lymphedema Continuum in Head and Neck Cancer | July 2010 | November 2014 | |
| NCT01268202 | Completed | Phase 2 | Curative Efficacy of Pravastatine in Patients Presented Delayed Cutaneous and Subcutaneous Radio-induced Fibrosis | December 17, 2010 | April 18, 2019 |
| NCT01296529 | Completed | Study on Immunopathogenesis in HIV and Hepatitis C Coinfection | July 2011 | July 2012 | |
| NCT01524562 | Completed | HIV Accelerated Liver Disease in Uganda | December 20, 2011 | December 17, 2019 | |
| NCT01655017 | Completed | N/A | Fibrosis a New Pathological Actor in Adipose Tissue | February 8, 2012 | April 6, 2018 |
| NCT01813045 | Completed | Angiogenesis and Fibrosis in Myocardial Infarction | April 2013 | March 2016 | |
| NCT01837160 | Completed | Angiogenesis and Fibrosis in Aortic Stenosis | April 2013 | August 2015 | |
| NCT06383819 | Completed | Phase 3 | Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19 | April 8, 2022 | December 31, 2023 |
| NCT00001729 | Completed | Phase 3 | Combination Drug Therapy for Patients With Hepatitis C | October 1997 | September 2002 |
| NCT00001959 | Completed | Phase 2 | Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) | December 1999 | October 2008 |
| NCT00039871 | Completed | Phase 3 | PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus Ribavirin (Study P02370) | May 2002 | September 2007 |
| NCT00234364 | Completed | Pergolide Treatment and Valvular Heart Disease | March 2005 | September 2007 | |
| NCT00252642 | Completed | N/A | Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C | November 2005 | September 2007 |
| NCT00347009 | Completed | Phase 4 | Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis | May 2005 | September 2009 |
| NCT02049307 | Completed | Phase 2 | Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial | October 16, 2014 | December 14, 2018 |
| NCT02132351 | Completed | Hepatic Fibrosis Non-invasive Methods Questionnaire | August 2013 | April 2016 | |
| NCT02161952 | Completed | Phase 2 | Pirfenidone, an Antifibrotic and Antiinflammatory Drug | May 2005 | August 2007 |
| NCT02407197 | Completed | International T1 Multicentre CMR Outcome Study | January 2011 | December 1, 2022 | |
| NCT02408744 | Completed | Phase 1/Phase 2 | Utility of Prolonged-release Pirfenidone in the Progression of Chronic Kidney Disease | September 2009 | September 2013 |
| NCT02412241 | Completed | N/A | Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients | June 2015 | August 2020 |
| NCT02480972 | Completed | N/A | Hepatic Fibrosis Assessment Using Multiparametric Magnetic Resonance Imaging | June 23, 2015 | August 28, 2020 |
| NCT02529319 | Completed | N/A | Efficacy of Delayed Enhancement MRI-Guided Ablation vs Conventional Catheter Ablation of Atrial Fibrillation | July 2016 | April 21, 2021 |
| NCT02604862 | Completed | Early Phase 1 | Imaging FIB ONE in the Human Lung Using Endomicroscopy | May 2016 | September 2018 |
| NCT02630303 | Completed | Phase 1 | High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin | January 2016 | March 2017 |
| NCT02648022 | Completed | N/A | Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting Antiviral Treatment | January 2012 | February 2014 |
| NCT02686762 | Completed | Phase 2 | Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis | January 26, 2016 | February 28, 2019 |
| NCT02774161 | Completed | N/A | B-mode Ultrasound Imaging in Detecting Early Liver Cancer | May 2016 | June 19, 2017 |
| NCT02790008 | Completed | Magnetic Resonance Imaging and Fibrosis | June 2015 | January 2021 | |
| NCT02904252 | Completed | The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital | January 1, 2016 | October 31, 2016 | |
| NCT02958345 | Completed | Phase 4 | Placebo Controlled Evaluation of the Cell Mediated Immune Response of Cirrhotic Subjects to Zostavax™ | June 2013 | July 2015 |
| NCT03000764 | Completed | N/A | RNA and Heat Shock Protein Biomarkers in Radiation-induced Fibrosis in Breast Cancer | May 10, 2017 | April 25, 2018 |
| NCT03030859 | Completed | N/A | Self-Care for Head and Neck Cancer Survivors With Lymphedema and Fibrosis | June 1, 2018 | March 31, 2022 |
| NCT03142165 | Completed | Phase 1 | A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986263 in Healthy Participants | May 11, 2017 | November 29, 2017 |
| NCT03241264 | Completed | Phase 1 | A Study of Safety, Tolerability, and the Effects Two ND-L02-s0201 Have on the Body | August 28, 2016 | October 21, 2016 |
| NCT03559166 | Completed | Phase 1 | First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis | July 11, 2018 | October 4, 2019 |
| NCT03738332 | Completed | N/A | Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study | February 25, 2019 | December 31, 2020 |
| NCT03795116 | Completed | Phase 2 | Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention | March 18, 2019 | October 26, 2020 |
| NCT03907540 | Completed | Phase 1 | Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 | April 5, 2019 | May 20, 2019 |
| NCT03979417 | Completed | Identification of Biomarkers Related to Liver Fibrosis as New Therapeutic Targets | September 30, 2019 | October 26, 2022 | |
| NCT04302428 | Completed | Zinc Status and Growth in Cystic Fibrosis | August 29, 2019 | March 30, 2021 | |
| NCT04423458 | Completed | Evaluation of Advanced US Tools in Assessing Allograft Complications | January 4, 2022 | September 30, 2022 | |
| NCT04468100 | Completed | Phase 3 | Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis | August 30, 2017 | May 16, 2018 |
| NCT04482855 | Completed | N/A | Low-Level Laser in Head and Neck Chronic Lymphedema | August 19, 2021 | June 30, 2023 |
| NCT04695041 | Completed | Phase 1 | A Healthy Volunteer Study of PBI-4050 | December 9, 2020 | October 5, 2021 |
| NCT04931147 | Completed | Phase 1 | A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers | May 13, 2021 | March 8, 2023 |
| NCT00001437 | Completed | Phase 2 | Trial of Pentoxifylline in Patients With Functional Disability Caused by Radiation-Induced Advanced Regional Fibrosis | June 1995 | March 2000 |
| NCT04925362 | Not yet recruiting | N/A | THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) | June 2021 | June 2036 |
| NCT05011305 | Recruiting | Phase 2 | Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis With Fibrosis | August 18, 2021 | July 2025 |
| NCT03025074 | Recruiting | Blood Collection Biorepository for Liver Disease Research | July 2013 | December 2099 | |
| NCT05253287 | Recruiting | Phase 2/Phase 3 | Growth Hormone in Decompensated Liver Cirrhosis | February 1, 2022 | January 2025 |
| NCT03308916 | Recruiting | N/A | Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers | October 6, 2017 | October 30, 2035 |
| NCT05330923 | Recruiting | Effect of NNRTI or INSTI on Nonalcoholic Steatosis in HIV/AIDS Patients | May 1, 2022 | January 1, 2027 | |
| NCT05402969 | Recruiting | Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools | January 12, 2023 | January 12, 2025 | |
| NCT05459259 | Recruiting | Physiotherapy for Arthrofibrosis Following Knee Replacement. | October 3, 2022 | August 30, 2023 | |
| NCT03853447 | Recruiting | Fibro-inflammatory Progression From Acute to Chronic Pancreatitis | February 14, 2019 | January 1, 2041 | |
| NCT05570058 | Recruiting | Phase 2 | Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis | September 8, 2022 | June 2024 |
| NCT05661123 | Recruiting | N/A | Effect of Modified Complete Decongestive Therapy on Lower Limbs Fibrosis Post Cellulitis | September 20, 2023 | June 2024 |
| NCT02322073 | Recruiting | Inflammation and Obesity-associated Disease | December 1, 2014 | December 2025 | |
| NCT05874492 | Recruiting | N/A | Evaluation of the Medical Benefit of Spa Therapy on Fibrosis After Postoperative Radiotherapy for Breast Cancer | January 29, 2024 | April 2026 |
| NCT05903001 | Recruiting | Diaphragmatic Function as a Biomarker | July 1, 2023 | June 30, 2025 | |
| NCT04831034 | Recruiting | Early Phase 1 | 68Ga-FAPI PET/CT in Patients With Various Fibrotic Disease | April 1, 2021 | April 1, 2024 |
| NCT02717650 | Recruiting | N/A | The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. | August 25, 2016 | October 2024 |
| NCT06149260 | Recruiting | Phase 1 | Subcutaneous Semaglutide in Systemic Scleroderma | February 29, 2024 | December 2024 |
| NCT04948840 | Recruiting | N/A | Pilot Study of the Predictive Value of TREM1 Expression and Activation in Inflammation and Radio-induced Mammary Fibrosis | April 1, 2022 | December 31, 2024 |
| NCT03780101 | Terminated | Pathology and Imaging in Kidney Allografts | February 15, 2019 | May 24, 2022 | |
| NCT03142191 | Terminated | Phase 2 | A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis | July 26, 2017 | December 24, 2021 |
| NCT03800069 | Terminated | Validation of Point of Care Liver Function Tests | December 3, 2018 | May 30, 2019 | |
| NCT01203943 | Terminated | Phase 2 | A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF) | January 1, 2011 | August 24, 2012 |
| NCT01978301 | Terminated | Phase 1 | Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars | April 15, 2014 | February 5, 2015 |
| NCT04212650 | Terminated | Phase 1/Phase 2 | Losartan to Improve Hip Microfracture | August 7, 2020 | December 4, 2020 |
| NCT02542020 | Unknown status | Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatosis | June 2015 | May 2022 | |
| NCT00148837 | Unknown status | Phase 2 | Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis | September 2004 | |
| NCT04795570 | Unknown status | Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors | September 1, 2020 | September 1, 2022 | |
| NCT03433222 | Unknown status | Phase 1 | Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III | January 31, 2018 | January 8, 2019 |
| NCT02948998 | Unknown status | Phase 4 | Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy | May 14, 2018 | July 2020 |
| NCT02826005 | Unknown status | N/A | Examination the Ability to Early Diagnose HCC by Combining Three Biomarkers Technology Developed by WAKO, And Their Relevance to Cirrhotic of Patients With Various Backgrounds and the Israeli Population. | July 2016 | August 2017 |
| NCT02294890 | Unknown status | Knee Stiffness in Fibrosis Diathesis | January 2015 | April 2015 | |
| NCT02898376 | Unknown status | Phase 3 | Clinical Benefit of Spa Care on Severe Radiation-induced Fibrosis After Postoperative Radiotherapy for Breast Cancer | December 2018 | December 2021 |
| NCT02327689 | Unknown status | Phase 4 | Emtricitabine Plus Adefovir Dipivoxil for Naive Chinese HBV Related Cirrhosis Patients | January 2015 | July 2017 |
| NCT01822405 | Unknown status | Phase 2 | Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen | July 2010 | July 2013 |
| NCT04934202 | Unknown status | Cohort Follow-up of Survivors of Hospitalization for COVID-19 During the 2nd Wave of the Epidemic in France | May 5, 2021 | May 5, 2022 | |
| NCT01898325 | Unknown status | N/A | Assessment Of Liver and Spleen Fibrosis in Patients With Gaucher Disease Using Fibroscan | August 2013 | December 2016 |
| NCT01483248 | Unknown status | Phase 1/Phase 2 | Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis | October 2010 | October 2015 |
| NCT02057965 | Unknown status | Phase 2 | Mesenchymal Stromal Cell Therapy in Renal Recipients | March 2014 | January 2022 |
| NCT02877953 | Unknown status | N/A | Transitional Care Interventions for Patients With Cirrhosis Post-TIPS | January 2013 | |
| NCT03013582 | Unknown status | N/A | Amniotic Membrane Wrapping and Tenolysis Versus Tenolysis Alone for Treatment of Tendon Adhesions of the Hand/Wrist | January 2017 | |
| NCT01246388 | Unknown status | Non-Invasive Evaluation of Fibrosis and Steatosis in Chronic Hepatopathy | May 2010 | December 2014 | |
| NCT01587222 | Withdrawn | Phase 2 | Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure | July 2016 | August 2017 |
| NCT01233674 | Withdrawn | Examination of Left Atrial Fibrosis Using MRI | March 2011 | March 2011 | |
| NCT02947516 | Withdrawn | N/A | Comparison of EUS-Guided Liver Biopsy With Percutaneous Liver Biopsy | January 2017 | December 2018 |
| NCT04001998 | Withdrawn | Phase 1 | Healthy Volunteer Study Comparing Tablet and Capsule Formulations | February 2021 | July 2021 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D005355