Cervical Intraepithelial Neoplasia
Information
- Disease name
- Cervical Intraepithelial Neoplasia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes | Mutation | Description | Source | Links |
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NCT ID | Status | Phase | Summary | Start date | Completion date |
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NCT03084081 | Active, not recruiting | N/A | An Innovative Treatment for Cervical Precancer (UH3) | August 1, 2017 | July 31, 2024 |
NCT02328872 | Active, not recruiting | N/A | Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia | January 2015 | March 2027 |
NCT02140021 | Active, not recruiting | N/A | Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer | October 27, 2014 | April 30, 2026 |
NCT04704908 | Active, not recruiting | Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m) | February 6, 2021 | December 2023 | |
NCT04537156 | Active, not recruiting | Phase 3 | Efficacy, Immunogenicity and Safty Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli) | September 5, 2020 | December 31, 2027 |
NCT03429582 | Active, not recruiting | N/A | Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device | October 30, 2020 | July 31, 2024 |
NCT05496231 | Active, not recruiting | Phase 2 | A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age | August 22, 2022 | June 14, 2024 |
NCT00337818 | Completed | Phase 3 | Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women | June 2006 | January 2009 |
NCT00443313 | Completed | Human Papillomavirus (HPV) Testing to Improve Cervical Cancer Screening in the Mississippi Delta | January 24, 2007 | June 25, 2015 | |
NCT00479375 | Completed | N/A | Randomized Controlled Trial of Human Papillomavirus Testing in Primary Cervical Cancer Screening | May 1997 | May 2007 |
NCT00596258 | Completed | Phase 2 | A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL) | November 2007 | August 2008 |
NCT00733109 | Completed | Phase 4 | Management of Cervical Intraepithelial Neoplasia Grade 2 | March 2003 | July 2007 |
NCT00741533 | Completed | Quality of Life in Thai Women Diagnosed Cervical Cancer at King Chulalongkorn Memorial Hospital | February 2008 | July 2009 | |
NCT00804466 | Completed | N/A | Human Papillomavirus Epidemiology in Nigeria | July 6, 2009 | November 10, 2020 |
NCT00931190 | Completed | Use of Human Papillomavirus Persistence for Determination of Treatment Efficacy Among Women With Cervical Dysplasia | February 2001 | November 2005 | |
NCT00941252 | Completed | Phase 2/Phase 3 | ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial | July 2009 | January 2011 |
NCT00995020 | Completed | Phase 3 | Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion | November 1999 | December 2010 |
NCT01022346 | Completed | Phase 2 | A Study of RO5217790 in Participants With High Grade Cervical Intraepithelial Neoplasia (CIN) Associated With High Risk Human Papillomavirus (HR-HPV) Infection | August 2009 | September 2013 |
NCT01029990 | Completed | Early Phase 1 | Randomized Controlled Trial to Study Interventions to Increase Participation in Cervical Cancer Screening Program | September 2009 | January 2011 |
NCT01058148 | Completed | A Comparison Study of Two Community Outreach-Based Approaches to Increase Participation of Women Living in the Mississippi Delta in Cervical Cancer Screening | December 22, 2009 | April 13, 2011 | |
NCT01131312 | Completed | Phase 3 | Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) | February 20, 2008 | February 5, 2009 |
NCT01145781 | Completed | N/A | Trial to Evaluate Single- and Double- Freeze Cryotherapy in the Prevention of Cervical Neoplasia | January 2010 | January 2015 |
NCT01160185 | Completed | Meta-analysis of Efficacy of Topotecan | June 2009 | July 2009 | |
NCT01256424 | Completed | Phase 2 | Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia | April 2011 | December 2012 |
NCT01298596 | Completed | N/A | Cryotherapy vs. LEEP to Treat Cervical Intraepithelial Neoplasia (CIN) 2/3 Among HIV-positive Women | June 2011 | January 2017 |
NCT00156026 | Completed | Phase 3 | Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1 | November 2000 | September 2007 |
NCT00190983 | Completed | Phase 2 | A Trial for Patients With Advanced/Recurrent Cervical Cancer | February 2005 | October 2007 |
NCT00237562 | Completed | Phase 3 | Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit | July 1999 | |
NCT00247169 | Completed | Phase 2 | Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II | August 2004 | April 2010 |
NCT00285207 | Completed | Phase 2 | Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix | January 2006 | June 2008 |
NCT00316706 | Completed | Phase 3 | Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine | October 2005 | January 2009 |
NCT00154089 | Completed | Phase 1/Phase 2 | A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia | November 2004 | December 2006 |
NCT01304524 | Completed | Phase 2 | A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3 | April 2011 | April 2015 |
NCT01338051 | Completed | Phase 1 | The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru | May 2011 | April 2012 |
NCT01345279 | Completed | Indirect Comparison Topotecan Cervical Carcinoma | June 2009 | July 2009 | |
NCT01349621 | Completed | Clinical Evaluation of Polarized Light Assisted Colposcopy | April 2011 | February 2014 | |
NCT01356823 | Completed | Phase 2 | Dose-Ranging Study of Recombinant Human Papillomavirus Virus 16/18 Bivalent Vaccine | March 2011 | October 2013 |
NCT01524003 | Completed | N/A | Chinese Cancer Prevention Study(CHICAPS) | November 2011 | January 2014 |
NCT01544478 | Completed | Phase 4 | V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) | November 25, 2011 | August 27, 2016 |
NCT01723956 | Completed | N/A | Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women | March 2010 | August 2014 |
NCT01735006 | Completed | Phase 3 | Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )Vaccine | November 22, 2012 | October 18, 2019 |
NCT01766284 | Completed | N/A | Study of the Diagnostic Efficacy of "Real Time" Niris 1300e Optical Coherence Tomography (OCT) Imaging System in the Management of Pre-invasive and Invasive Neoplasia of the Uterine Cervix | November 2012 | November 2012 |
NCT01826045 | Completed | Phase 2 | Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia | June 2013 | January 2016 |
NCT01929993 | Completed | Phase 3 | A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins | January 2008 | February 2012 |
NCT02095561 | Completed | N/A | Evaluation of Human Papilloma Virus (HPV) Self-testing to Increase Screening Uptake | July 2012 | December 2013 |
NCT02130323 | Completed | Phase 2/Phase 3 | Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix | February 2015 | May 9, 2017 |
NCT02139267 | Completed | Phase 2 | Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia | July 2014 | March 2016 |
NCT02184975 | Completed | Phase 2 | Cold Knife Conization With and Without Lateral Hemostatic Sutures | March 2009 | October 2013 |
NCT02195089 | Completed | Phase 1/Phase 2 | Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3) | March 2014 | April 2016 |
NCT02198365 | Completed | Comparison of Human Papillomavirus Integrated DNA and Messenger RNA in Cervical Neoplasia | January 2007 | March 2009 | |
NCT02237326 | Completed | N/A | Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women | October 2011 | October 2012 |
NCT02247999 | Completed | Improving Cervical Cancer Screening Among HIV-Infected Women in India | November 28, 2012 | October 8, 2020 | |
NCT02304770 | Completed | Phase 2 | Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia | January 2015 | January 2017 |
NCT02368054 | Completed | Phase 4 | Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization | May 2015 | February 2016 |
NCT02398916 | Completed | N/A | Music Listening to Reduce Pain and Anxiety During LEEP | February 2015 | August 2016 |
NCT02481414 | Completed | Phase 2 | A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions | November 30, 2015 | September 14, 2022 |
NCT02494310 | Completed | N/A | HRME: Screening for Cervical Cancer and Its Precursors in Low-Resource Settings | September 1, 2015 | December 31, 2016 |
NCT02540421 | Completed | Recurrence in High-grade Lesions After Conization | January 2001 | December 2007 | |
NCT02562508 | Completed | Phase 3 | A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | December 5, 2015 | August 12, 2016 |
NCT02631863 | Completed | Phase 2 | Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1) | March 22, 2016 | November 24, 2018 |
NCT02733068 | Completed | Phase 3 | A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine. | November 2, 2014 | January 16, 2020 |
NCT02740777 | Completed | Phase 2 | Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females | February 2016 | July 2019 |
NCT02749110 | Completed | N/A | Participation in Screening for Cervical Cancer: Interest of a Self-sampling Device Provided by the General Practitioner | August 28, 2016 | February 23, 2021 |
NCT02814448 | Completed | N/A | An Innovative Treatment for Cervical Pre Cancer | February 2016 | December 2016 |
NCT02864147 | Completed | Phase 2 | Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) | July 2016 | November 22, 2022 |
NCT02907333 | Completed | N/A | Testing Use of Condoms on Regression of Cervical Intraepithelial Neoplasia | September 2016 | September 2019 |
NCT02934724 | Completed | Impact of HPV Vaccine On The Prevalence Of HPV In Norway | November 2016 | February 2017 | |
NCT03105856 | Completed | Phase 4 | FASTER-Tlalpan Study in Mexico: HPV Vaccination Impact on Cervical Cancer Screening Program | January 3, 2017 | December 15, 2018 |
NCT03206255 | Completed | Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls | July 1, 2017 | August 15, 2018 | |
NCT03239223 | Completed | Phase 1 | Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection | January 1, 2018 | October 30, 2018 |
NCT03293628 | Completed | Phase 2 | Comparing Two Techniques of Haemostasis After Cervical Conization | October 1, 2014 | January 30, 2016 |
NCT03355820 | Completed | Phase 3 | A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study | February 28, 2018 | June 29, 2018 |
NCT03436251 | Completed | N/A | Local Hyperthermia for the Treatment of Cervical Intraepithelial Neoplasias | January 28, 2018 | August 1, 2020 |
NCT03438006 | Completed | A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects | May 31, 2018 | December 3, 2020 | |
NCT03629886 | Completed | Phase 4 | Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study | August 22, 2018 | February 28, 2020 |
NCT03788850 | Completed | Factors Associated With Residual Disease In The Central Cone | January 1, 2006 | August 15, 2016 | |
NCT04333212 | Completed | N/A | HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix | December 12, 2012 | July 8, 2014 |
NCT04480866 | Completed | N/A | CASUS: Improved and Quality Assured Collection of First-void Urine | July 30, 2019 | November 27, 2019 |
NCT04530201 | Completed | N/A | CASUS: Validation for Detection of Precursor Lesions | August 20, 2020 | February 28, 2022 |
NCT05426148 | Completed | Phase 4 | Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female | May 1, 2020 | April 30, 2021 |
NCT05996796 | Completed | N/A | Dry Run of the ScreenUrSelf Trial | April 10, 2023 | June 15, 2023 |
NCT04266093 | Enrolling by invitation | Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies | May 8, 2020 | October 1, 2050 | |
NCT05595252 | Enrolling by invitation | Retrospective Study on the Evolution of CIN 1 to 3 in Per and Postpartum in Nancy From 2014 to 2022 | January 1, 2014 | December 31, 2022 | |
NCT06243666 | Not yet recruiting | Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls | February 20, 2024 | December 31, 2026 | |
NCT06191133 | Not yet recruiting | Phase 1 | Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma | August 1, 2024 | May 31, 2025 |
NCT05510830 | Not yet recruiting | N/A | Diagnostic Cervical Conization for Persistent Infection or Integration of HPV | October 2022 | January 2030 |
NCT03848039 | Not yet recruiting | Phase 3 | Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9 | December 2020 | May 2028 |
NCT06015854 | Recruiting | Phase 2 | Vvax001 Cancer Vaccine in Premalignant Cervical Lesions - Phase II | March 23, 2021 | April 1, 2024 |
NCT05502367 | Recruiting | Phase 1/Phase 2 | A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia | September 10, 2022 | May 31, 2024 |
NCT04712851 | Recruiting | Phase 2 | Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia | June 30, 2021 | January 31, 2026 |
NCT04783805 | Recruiting | Conservative Management of HSIL in Patients With Future Pregnancy Aspiration | March 3, 2021 | December 31, 2027 | |
NCT05284877 | Recruiting | The Organ Transplant Recipient HPV and Skin Cancer Study | March 10, 2022 | April 2027 | |
NCT05931354 | Recruiting | Longitudinal HPV Pap in CIN and VAIN | July 1, 2017 | June 30, 2024 | |
NCT02858310 | Recruiting | Phase 1/Phase 2 | E7 TCR T Cells for Human Papillomavirus-Associated Cancers | January 27, 2017 | January 1, 2026 |
NCT05266898 | Recruiting | Phase 4 | Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV | November 30, 2022 | March 2025 |
NCT05996783 | Recruiting | N/A | Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial | May 25, 2023 | September 30, 2026 |
NCT05282095 | Recruiting | Effect of HPV Integration on Prognosis of Young Women With CIN2 in China | June 1, 2022 | May 31, 2025 | |
NCT05405270 | Recruiting | Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment | June 1, 2022 | December 2026 | |
NCT05309122 | Recruiting | Cervical Cancer Screening Strategies | March 19, 2022 | March 19, 2025 | |
NCT04969445 | Recruiting | The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female | March 30, 2021 | January 2024 | |
NCT05045755 | Recruiting | The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female | April 13, 2021 | January 2024 | |
NCT05078528 | Recruiting | N/A | Low-cost Imaging Technology for Global Prevention of Cervical Cancer | September 20, 2021 | December 3, 2025 |
NCT05142397 | Recruiting | The Dynamic Process of VMB and Mucosal Immunity After FUS Treatment of CIN Patients With Fertility Requirement | August 15, 2021 | June 30, 2023 | |
NCT05229679 | Recruiting | N/A | HPV-based Screening Among Women 23-29 Years of Age | November 16, 2020 | December 31, 2038 |
NCT00682552 | Terminated | N/A | Evaluation of Initial High Risk Human Papillomavirus (HR-HPV) Viral Load as Predictive Marker for Cervical Intraepithelial Neoplasia Grade 1 (CIN1) Persistence | May 2008 | February 2013 |
NCT00708942 | Terminated | Phase 2 | Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) of Cervical Intraepithelial Neoplasia (CIN) Grade 1 | January 2009 | January 2012 |
NCT02329171 | Terminated | Phase 3 | Imiquimod Treatment of CIN Lesions | December 2014 | June 2016 |
NCT01116245 | Terminated | Phase 2 | An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+ | April 2010 | April 2016 |
NCT01283763 | Terminated | Phase 3 | Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia | May 2013 | January 2018 |
NCT02917746 | Unknown status | N/A | Imiquimod Treatment of High-grade CIN | November 2016 | December 2020 |
NCT01058460 | Unknown status | N/A | HPV-cytology Testing Versus Cytology Testing for the Detection of High Grade CIN | June 2010 | June 2017 |
NCT05290428 | Unknown status | DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening | March 12, 2022 | December 12, 2022 | |
NCT03218436 | Unknown status | N/A | Physical Cold Atmospheric Plasma for the Treatment of Cervical Intraepithelial Neoplasia | August 31, 2017 | July 1, 2021 |
NCT01487681 | Unknown status | Prevaccination Study of Cervical Human Papillomavirus Types in Yangtze River Delta Area, China | November 2011 | October 2013 | |
NCT03321461 | Unknown status | Phase 1 | TMTP1-ICG Mapping in Colposcopy-directed Biopsy | November 1, 2017 | December 2021 |
NCT00493545 | Unknown status | Phase 1 | Safety Study to Test the Safety of HspE7 and Poly-ICLC Given in Patients With Cervical Intraepithelial Neoplasia | May 2007 | June 2008 |
NCT00728871 | Unknown status | N/A | The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and Cervical Intraepithelial Neoplasia (CIN) Patients and Their Prognosis | December 2005 | December 2011 |
NCT01880411 | Unknown status | Phase 1 | Phase I, Open-Label Study of the Safety, Tolerability, and Immunogenicity PEK Fusion Protein Vaccine | June 2013 | June 2014 |
NCT03745846 | Unknown status | Phase 2 | A Efficacy and Safety Study of Composite Gel Containing Black Raspberry Extract in Removing HPV From Patients With Cervical Intraepithelial Neoplasia(CIN) After Cervical Conization | December 2018 | December 2019 |
NCT03870113 | Unknown status | Phase 1 | DC Vaccines Targeting HPV16/18 E6/E7 Protein to Regress CINI/CIN2 | April 1, 2019 | December 30, 2022 |
NCT04073082 | Unknown status | Safety and Efficacy of Laser Therapy in Gynaecology | July 24, 2019 | January 24, 2020 | |
NCT01095198 | Unknown status | Phase 2/Phase 3 | Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) | April 2010 | January 2013 |
NCT04646954 | Unknown status | Phase 3 | DNA Methylation Testing for the Screening of Uterine Cervical Lesion | November 26, 2020 | November 26, 2022 |
NCT04650711 | Unknown status | Phase 2 | Immunohistochemical Staining of p16 for the Screening of Cervical Cancer | November 26, 2020 | November 26, 2020 |
NCT02554344 | Unknown status | Early Phase 1 | Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs) | March 2016 | January 2017 |
NCT02576158 | Unknown status | HPV Integration Testing for Cervical Cancer Screening | April 2015 | April 2020 | |
NCT02576262 | Unknown status | HPV Integration Testing for Human Papillomavirus-Positive Women | September 2015 | September 2020 | |
NCT02596243 | Unknown status | Phase 2 | Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E) | August 2015 | August 2018 |
NCT02605941 | Unknown status | DNA Methylation Biomarkers for Cervical Cancer Screening | February 2014 | August 2016 | |
NCT02629510 | Unknown status | Phase 4 | The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) | January 2015 | August 2017 |
NCT02669459 | Unknown status | Phase 3 | Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol | May 2016 | March 2020 |
NCT04411134 | Withdrawn | Phase 1 | E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial Neoplasia | May 28, 2020 | July 14, 2020 |
NCT03143491 | Withdrawn | Phase 2 | Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN) | October 1, 2017 | March 1, 2019 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D018290