Cervical Intraepithelial Neoplasia

Search with Google Search with Bing
Information
Disease name
Cervical Intraepithelial Neoplasia
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03084081 Active, not recruiting N/A An Innovative Treatment for Cervical Precancer (UH3) August 1, 2017 July 31, 2024
NCT02328872 Active, not recruiting N/A Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia January 2015 March 2027
NCT02140021 Active, not recruiting N/A Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer October 27, 2014 April 30, 2026
NCT04704908 Active, not recruiting Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m) February 6, 2021 December 2023
NCT04537156 Active, not recruiting Phase 3 Efficacy, Immunogenicity and Safty Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli) September 5, 2020 December 31, 2027
NCT03429582 Active, not recruiting N/A Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device October 30, 2020 July 31, 2024
NCT05496231 Active, not recruiting Phase 2 A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age August 22, 2022 June 14, 2024
NCT00337818 Completed Phase 3 Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women June 2006 January 2009
NCT00443313 Completed Human Papillomavirus (HPV) Testing to Improve Cervical Cancer Screening in the Mississippi Delta January 24, 2007 June 25, 2015
NCT00479375 Completed N/A Randomized Controlled Trial of Human Papillomavirus Testing in Primary Cervical Cancer Screening May 1997 May 2007
NCT00596258 Completed Phase 2 A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL) November 2007 August 2008
NCT00733109 Completed Phase 4 Management of Cervical Intraepithelial Neoplasia Grade 2 March 2003 July 2007
NCT00741533 Completed Quality of Life in Thai Women Diagnosed Cervical Cancer at King Chulalongkorn Memorial Hospital February 2008 July 2009
NCT00804466 Completed N/A Human Papillomavirus Epidemiology in Nigeria July 6, 2009 November 10, 2020
NCT00931190 Completed Use of Human Papillomavirus Persistence for Determination of Treatment Efficacy Among Women With Cervical Dysplasia February 2001 November 2005
NCT00941252 Completed Phase 2/Phase 3 ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-Trial July 2009 January 2011
NCT00995020 Completed Phase 3 Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion November 1999 December 2010
NCT01022346 Completed Phase 2 A Study of RO5217790 in Participants With High Grade Cervical Intraepithelial Neoplasia (CIN) Associated With High Risk Human Papillomavirus (HR-HPV) Infection August 2009 September 2013
NCT01029990 Completed Early Phase 1 Randomized Controlled Trial to Study Interventions to Increase Participation in Cervical Cancer Screening Program September 2009 January 2011
NCT01058148 Completed A Comparison Study of Two Community Outreach-Based Approaches to Increase Participation of Women Living in the Mississippi Delta in Cervical Cancer Screening December 22, 2009 April 13, 2011
NCT01131312 Completed Phase 3 Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS) February 20, 2008 February 5, 2009
NCT01145781 Completed N/A Trial to Evaluate Single- and Double- Freeze Cryotherapy in the Prevention of Cervical Neoplasia January 2010 January 2015
NCT01160185 Completed Meta-analysis of Efficacy of Topotecan June 2009 July 2009
NCT01256424 Completed Phase 2 Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia April 2011 December 2012
NCT01298596 Completed N/A Cryotherapy vs. LEEP to Treat Cervical Intraepithelial Neoplasia (CIN) 2/3 Among HIV-positive Women June 2011 January 2017
NCT00156026 Completed Phase 3 Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1 November 2000 September 2007
NCT00190983 Completed Phase 2 A Trial for Patients With Advanced/Recurrent Cervical Cancer February 2005 October 2007
NCT00237562 Completed Phase 3 Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit July 1999
NCT00247169 Completed Phase 2 Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II August 2004 April 2010
NCT00285207 Completed Phase 2 Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix January 2006 June 2008
NCT00316706 Completed Phase 3 Human Papilloma Virus (HPV) Vaccine Trial in Young Adolescent Women With GlaxoSmithKline Biologicals' (GSK Bio) HPV-16/18 Vaccine October 2005 January 2009
NCT00154089 Completed Phase 1/Phase 2 A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia November 2004 December 2006
NCT01304524 Completed Phase 2 A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3 April 2011 April 2015
NCT01338051 Completed Phase 1 The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru May 2011 April 2012
NCT01345279 Completed Indirect Comparison Topotecan Cervical Carcinoma June 2009 July 2009
NCT01349621 Completed Clinical Evaluation of Polarized Light Assisted Colposcopy April 2011 February 2014
NCT01356823 Completed Phase 2 Dose-Ranging Study of Recombinant Human Papillomavirus Virus 16/18 Bivalent Vaccine March 2011 October 2013
NCT01524003 Completed N/A Chinese Cancer Prevention Study(CHICAPS) November 2011 January 2014
NCT01544478 Completed Phase 4 V501 Safety and Efficacy Study in Japanese Women Aged 16 to 26 Years (V501-110) November 25, 2011 August 27, 2016
NCT01723956 Completed N/A Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women March 2010 August 2014
NCT01735006 Completed Phase 3 Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )Vaccine November 22, 2012 October 18, 2019
NCT01766284 Completed N/A Study of the Diagnostic Efficacy of "Real Time" Niris 1300e Optical Coherence Tomography (OCT) Imaging System in the Management of Pre-invasive and Invasive Neoplasia of the Uterine Cervix November 2012 November 2012
NCT01826045 Completed Phase 2 Efficacy and Safety Study of PGA (Poly-gamma Glutamic Acid) for Cervical Intraepithelial Neoplasia June 2013 January 2016
NCT01929993 Completed Phase 3 A Trial of Two Electrosurgical Conizations: Histopathological Analysis of Excision Margins January 2008 February 2012
NCT02095561 Completed N/A Evaluation of Human Papilloma Virus (HPV) Self-testing to Increase Screening Uptake July 2012 December 2013
NCT02130323 Completed Phase 2/Phase 3 Topical Imiquimod vs. LEEP for Women With Carcinoma In-situ of the Cervix February 2015 May 9, 2017
NCT02139267 Completed Phase 2 Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia July 2014 March 2016
NCT02184975 Completed Phase 2 Cold Knife Conization With and Without Lateral Hemostatic Sutures March 2009 October 2013
NCT02195089 Completed Phase 1/Phase 2 Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3) March 2014 April 2016
NCT02198365 Completed Comparison of Human Papillomavirus Integrated DNA and Messenger RNA in Cervical Neoplasia January 2007 March 2009
NCT02237326 Completed N/A Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women October 2011 October 2012
NCT02247999 Completed Improving Cervical Cancer Screening Among HIV-Infected Women in India November 28, 2012 October 8, 2020
NCT02304770 Completed Phase 2 Aminolaevulinic Acid Photodynamic Therapy of Cervical Persistent HPV Infection and Cervical Neoplasia January 2015 January 2017
NCT02368054 Completed Phase 4 Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization May 2015 February 2016
NCT02398916 Completed N/A Music Listening to Reduce Pain and Anxiety During LEEP February 2015 August 2016
NCT02481414 Completed Phase 2 A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions November 30, 2015 September 14, 2022
NCT02494310 Completed N/A HRME: Screening for Cervical Cancer and Its Precursors in Low-Resource Settings September 1, 2015 December 31, 2016
NCT02540421 Completed Recurrence in High-grade Lesions After Conization January 2001 December 2007
NCT02562508 Completed Phase 3 A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls December 5, 2015 August 12, 2016
NCT02631863 Completed Phase 2 Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1) March 22, 2016 November 24, 2018
NCT02733068 Completed Phase 3 A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine. November 2, 2014 January 16, 2020
NCT02740777 Completed Phase 2 Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females February 2016 July 2019
NCT02749110 Completed N/A Participation in Screening for Cervical Cancer: Interest of a Self-sampling Device Provided by the General Practitioner August 28, 2016 February 23, 2021
NCT02814448 Completed N/A An Innovative Treatment for Cervical Pre Cancer February 2016 December 2016
NCT02864147 Completed Phase 2 Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) July 2016 November 22, 2022
NCT02907333 Completed N/A Testing Use of Condoms on Regression of Cervical Intraepithelial Neoplasia September 2016 September 2019
NCT02934724 Completed Impact of HPV Vaccine On The Prevalence Of HPV In Norway November 2016 February 2017
NCT03105856 Completed Phase 4 FASTER-Tlalpan Study in Mexico: HPV Vaccination Impact on Cervical Cancer Screening Program January 3, 2017 December 15, 2018
NCT03206255 Completed Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls July 1, 2017 August 15, 2018
NCT03239223 Completed Phase 1 Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection January 1, 2018 October 30, 2018
NCT03293628 Completed Phase 2 Comparing Two Techniques of Haemostasis After Cervical Conization October 1, 2014 January 30, 2016
NCT03355820 Completed Phase 3 A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study February 28, 2018 June 29, 2018
NCT03436251 Completed N/A Local Hyperthermia for the Treatment of Cervical Intraepithelial Neoplasias January 28, 2018 August 1, 2020
NCT03438006 Completed A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects May 31, 2018 December 3, 2020
NCT03629886 Completed Phase 4 Safety and Protective Effect Study of GSK Biologicals' Human Papillomavirus (Types 16, 18) Vaccine, Adsorbed (GSK580299) in Healthy Female Subjects From the HPV-039 Study August 22, 2018 February 28, 2020
NCT03788850 Completed Factors Associated With Residual Disease In The Central Cone January 1, 2006 August 15, 2016
NCT04333212 Completed N/A HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix December 12, 2012 July 8, 2014
NCT04480866 Completed N/A CASUS: Improved and Quality Assured Collection of First-void Urine July 30, 2019 November 27, 2019
NCT04530201 Completed N/A CASUS: Validation for Detection of Precursor Lesions August 20, 2020 February 28, 2022
NCT05426148 Completed Phase 4 Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female May 1, 2020 April 30, 2021
NCT05996796 Completed N/A Dry Run of the ScreenUrSelf Trial April 10, 2023 June 15, 2023
NCT04266093 Enrolling by invitation Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies May 8, 2020 October 1, 2050
NCT05595252 Enrolling by invitation Retrospective Study on the Evolution of CIN 1 to 3 in Per and Postpartum in Nancy From 2014 to 2022 January 1, 2014 December 31, 2022
NCT06243666 Not yet recruiting Long-term Effectiveness and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Preadolescent Girls February 20, 2024 December 31, 2026
NCT06191133 Not yet recruiting Phase 1 Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma August 1, 2024 May 31, 2025
NCT05510830 Not yet recruiting N/A Diagnostic Cervical Conization for Persistent Infection or Integration of HPV October 2022 January 2030
NCT03848039 Not yet recruiting Phase 3 Impact on Disease Relapse of HPV Vaccination in Women Treated With LEEP for Cervical Intraepithelial Neoplasia. HOPE9 December 2020 May 2028
NCT06015854 Recruiting Phase 2 Vvax001 Cancer Vaccine in Premalignant Cervical Lesions - Phase II March 23, 2021 April 1, 2024
NCT05502367 Recruiting Phase 1/Phase 2 A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia September 10, 2022 May 31, 2024
NCT04712851 Recruiting Phase 2 Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia June 30, 2021 January 31, 2026
NCT04783805 Recruiting Conservative Management of HSIL in Patients With Future Pregnancy Aspiration March 3, 2021 December 31, 2027
NCT05284877 Recruiting The Organ Transplant Recipient HPV and Skin Cancer Study March 10, 2022 April 2027
NCT05931354 Recruiting Longitudinal HPV Pap in CIN and VAIN July 1, 2017 June 30, 2024
NCT02858310 Recruiting Phase 1/Phase 2 E7 TCR T Cells for Human Papillomavirus-Associated Cancers January 27, 2017 January 1, 2026
NCT05266898 Recruiting Phase 4 Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV November 30, 2022 March 2025
NCT05996783 Recruiting N/A Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial May 25, 2023 September 30, 2026
NCT05282095 Recruiting Effect of HPV Integration on Prognosis of Young Women With CIN2 in China June 1, 2022 May 31, 2025
NCT05405270 Recruiting Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment June 1, 2022 December 2026
NCT05309122 Recruiting Cervical Cancer Screening Strategies March 19, 2022 March 19, 2025
NCT04969445 Recruiting The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female March 30, 2021 January 2024
NCT05045755 Recruiting The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female April 13, 2021 January 2024
NCT05078528 Recruiting N/A Low-cost Imaging Technology for Global Prevention of Cervical Cancer September 20, 2021 December 3, 2025
NCT05142397 Recruiting The Dynamic Process of VMB and Mucosal Immunity After FUS Treatment of CIN Patients With Fertility Requirement August 15, 2021 June 30, 2023
NCT05229679 Recruiting N/A HPV-based Screening Among Women 23-29 Years of Age November 16, 2020 December 31, 2038
NCT00682552 Terminated N/A Evaluation of Initial High Risk Human Papillomavirus (HR-HPV) Viral Load as Predictive Marker for Cervical Intraepithelial Neoplasia Grade 1 (CIN1) Persistence May 2008 February 2013
NCT00708942 Terminated Phase 2 Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) of Cervical Intraepithelial Neoplasia (CIN) Grade 1 January 2009 January 2012
NCT02329171 Terminated Phase 3 Imiquimod Treatment of CIN Lesions December 2014 June 2016
NCT01116245 Terminated Phase 2 An Assessment of an Attenuated Live Listeria Vaccine in CIN 2+ April 2010 April 2016
NCT01283763 Terminated Phase 3 Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia May 2013 January 2018
NCT02917746 Unknown status N/A Imiquimod Treatment of High-grade CIN November 2016 December 2020
NCT01058460 Unknown status N/A HPV-cytology Testing Versus Cytology Testing for the Detection of High Grade CIN June 2010 June 2017
NCT05290428 Unknown status DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening March 12, 2022 December 12, 2022
NCT03218436 Unknown status N/A Physical Cold Atmospheric Plasma for the Treatment of Cervical Intraepithelial Neoplasia August 31, 2017 July 1, 2021
NCT01487681 Unknown status Prevaccination Study of Cervical Human Papillomavirus Types in Yangtze River Delta Area, China November 2011 October 2013
NCT03321461 Unknown status Phase 1 TMTP1-ICG Mapping in Colposcopy-directed Biopsy November 1, 2017 December 2021
NCT00493545 Unknown status Phase 1 Safety Study to Test the Safety of HspE7 and Poly-ICLC Given in Patients With Cervical Intraepithelial Neoplasia May 2007 June 2008
NCT00728871 Unknown status N/A The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and Cervical Intraepithelial Neoplasia (CIN) Patients and Their Prognosis December 2005 December 2011
NCT01880411 Unknown status Phase 1 Phase I, Open-Label Study of the Safety, Tolerability, and Immunogenicity PEK Fusion Protein Vaccine June 2013 June 2014
NCT03745846 Unknown status Phase 2 A Efficacy and Safety Study of Composite Gel Containing Black Raspberry Extract in Removing HPV From Patients With Cervical Intraepithelial Neoplasia(CIN) After Cervical Conization December 2018 December 2019
NCT03870113 Unknown status Phase 1 DC Vaccines Targeting HPV16/18 E6/E7 Protein to Regress CINI/CIN2 April 1, 2019 December 30, 2022
NCT04073082 Unknown status Safety and Efficacy of Laser Therapy in Gynaecology July 24, 2019 January 24, 2020
NCT01095198 Unknown status Phase 2/Phase 3 Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV) April 2010 January 2013
NCT04646954 Unknown status Phase 3 DNA Methylation Testing for the Screening of Uterine Cervical Lesion November 26, 2020 November 26, 2022
NCT04650711 Unknown status Phase 2 Immunohistochemical Staining of p16 for the Screening of Cervical Cancer November 26, 2020 November 26, 2020
NCT02554344 Unknown status Early Phase 1 Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs) March 2016 January 2017
NCT02576158 Unknown status HPV Integration Testing for Cervical Cancer Screening April 2015 April 2020
NCT02576262 Unknown status HPV Integration Testing for Human Papillomavirus-Positive Women September 2015 September 2020
NCT02596243 Unknown status Phase 2 Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E) August 2015 August 2018
NCT02605941 Unknown status DNA Methylation Biomarkers for Cervical Cancer Screening February 2014 August 2016
NCT02629510 Unknown status Phase 4 The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) January 2015 August 2017
NCT02669459 Unknown status Phase 3 Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol May 2016 March 2020
NCT04411134 Withdrawn Phase 1 E7 TCR T Cell Immunotherapy for High-Grade Cervical Intraepithelial Neoplasia May 28, 2020 July 14, 2020
NCT03143491 Withdrawn Phase 2 Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN) October 1, 2017 March 1, 2019
MeSH unique ID (MeSH (Medical Subject Headings))
D018290