diarrhea
Information
- Disease name
- diarrhea
- Disease ID
- DOID:13250
- Description
- "A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea." [url:http\://en.wikipedia.org/wiki/Diarrhea#Types_of_diarrhea]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| MECP2 | X | 154,021,573 | 154,097,717 | 4 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05812820 | Active, not recruiting | N/A | Effects of Probiotic in Treatment of Persistent Diarrhea in Children | July 1, 2022 | June 15, 2024 |
| NCT03499808 | Active, not recruiting | Phase 2 | S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis | June 6, 2018 | July 31, 2025 |
| NCT04658914 | Active, not recruiting | Phase 2 | Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa | April 15, 2021 | October 2023 |
| NCT02414399 | Active, not recruiting | Phase 4 | Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children | June 28, 2016 | December 28, 2025 |
| NCT05569330 | Active, not recruiting | N/A | Effect of Aerosol Filtering on Infectious Diseases in Day Care | November 1, 2022 | April 30, 2024 |
| NCT05933525 | Active, not recruiting | Phase 2 | Clinical Study to Assess the Efficacy of IMM-124E (Travelan®) in a Controlled Human Infection Model | May 29, 2023 | July 2024 |
| NCT03767257 | Active, not recruiting | Phase 2 | A Study of Colesevelam for Lenalidomide-Associated Diarrhea | December 3, 2018 | June 2024 |
| NCT04182633 | Active, not recruiting | Phase 2 | MTT for Children With ASD Who Have Gastrointestinal Disorders | November 15, 2019 | December 30, 2024 |
| NCT00033605 | Completed | Phase 3 | Octreotide in Preventing Diarrhea in Patients Who Are Undergoing Radiation Therapy to the Pelvis | April 2002 | July 2006 |
| NCT00048971 | Completed | Genetic Trial to Study Diarrhea in Patients With Stage III Colon Cancer Who Are Receiving Chemotherapy | April 2002 | November 2006 | |
| NCT00050635 | Completed | Phase 4 | STOP Trial - Sandostatin LAR Depot Trial for the Optimum Prevention of Chemotherapy Induced Diarrhea | December 2002 | July 2003 |
| NCT00058942 | Completed | N/A | A Trial of Tap Water Treatment in the Elderly | January 2000 | November 2006 |
| NCT00082069 | Completed | Phase 1 | Invaplex 50 Vaccine Dose-Ranging | April 2004 | November 2006 |
| NCT00084721 | Completed | Phase 1 | Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer | March 2005 | |
| NCT00093353 | Completed | Phase 1 | N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma | May 2004 | |
| NCT00097422 | Completed | Phase 2 | OPT-80 in Clostridium Difficile-Associated Diarrhea (CDAD) | November 1, 2004 | April 1, 2005 |
| NCT00098384 | Completed | Phase 2 | Rifaximin Versus Placebo in the Prevention of Travelers' Diarrhea | June 2003 | September 2003 |
| NCT00101725 | Completed | Phase 2 | A Study of Crofelemer to Treat Diarrhea Irritable Bowel Syndrome | December 2004 | November 2005 |
| NCT00118872 | Completed | N/A | Beneficial Bacteria to Prevent Malnutrition and Diarrhea in Pakistani Infants | March 2006 | March 2008 |
| NCT00120744 | Completed | N/A | Oral Disintegrating Ondansetron Tablet to Reduce Vomiting From Gastroenteritis in a Pediatric Emergency Department | January 2004 | April 2005 |
| NCT00137657 | Completed | Phase 4 | Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance | February 2002 | November 2003 |
| NCT00143533 | Completed | Phase 1 | Prevention of Diarrhea in Patients Taking IV Irinotecan for Relapsed or Difficult to Treat Pediatric Solid Tumors | September 2003 | June 2011 |
| NCT00196794 | Completed | Phase 3 | A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea | April 2005 | August 2007 |
| NCT00198796 | Completed | Phase 1 | Dose-finding Study of WS6788A, DS37-4 and H10407 Enterotoxigenic Escherichia Coli (ETEC) Challenge Strains | September 2005 | May 30, 2007 |
| NCT00228254 | Completed | Phase 4 | Vitamin A and Zinc: Prevention of Pneumonia (VAZPOP) Study | January 2000 | June 2004 |
| NCT00252928 | Completed | N/A | Health Impact Study of Aquatabs in Tamale, Ghana | July 2006 | November 2006 |
| NCT00255385 | Completed | Phase 3 | Efficacy of Bifidus DR10 and Oligo Saccharides / Micronutrient Fortification of Milk | April 2002 | April 2004 |
| NCT00258180 | Completed | Phase 2 | Cyclophosphamide in Treating Young Patients With Severe Autoimmune Enteropathy | August 15, 2005 | February 24, 2009 |
| NCT00258401 | Completed | N/A | Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy. | May 2005 | June 2006 |
| NCT00265369 | Completed | Phase 3 | TEDDY: Spores of Bacillus Clausii in Acute Diarrhoea in Children | May 2004 | |
| NCT00269399 | Completed | Phase 3 | A Trial to Compare Xifaxan to Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) | December 2005 | December 2008 |
| NCT00269542 | Completed | N/A | Impact of Zinc Supplementation on Mortality and Hospitalizations in Children Aged 1 Months to 23 Months | February 2002 | August 2003 |
| NCT00272116 | Completed | N/A | Effect of Zinc and Vitamin A Supplementation on Diarrhea, Physical Growth and Immune Response in Malnourished Children | February 1998 | September 2000 |
| NCT00272142 | Completed | N/A | Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial | January 2005 | August 2007 |
| NCT00276328 | Completed | Phase 4 | Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults | January 2005 | July 2006 |
| NCT00278681 | Completed | Phase 1 | Effectiveness of Adding Zinc to the Current Case Management Package of Diarrhea in a Primary Health Care Setting | August 2003 | August 2004 |
| NCT00278746 | Completed | N/A | Addition of Zinc to the Current Case Management Package of Diarrhea in a Primary Health Care Setting | January 2005 | September 2006 |
| NCT00289224 | Completed | Phase 3 | Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata | July 2006 | May 2013 |
| NCT00314951 | Completed | Phase 3 | Fidaxomicin Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) (MK-5119-018) | May 2, 2006 | August 21, 2008 |
| NCT00328263 | Completed | Phase 3 | Efficacy and Safety of BIO-K + CL1285 in Prevention of Antibiotic-associated Diarrhea in Hospitalized Adult Patients | March 2006 | October 2007 |
| NCT00328380 | Completed | Phase 3 | Prevention of Travelers' Diarrhea in Subjects Traveling Outside the U.S. | December 2005 | September 2008 |
| NCT00359970 | Completed | Phase 4 | Azithromycin, With or Without Loperamide, to Treat Travelers' Diarrhea | June 2002 | August 2003 |
| NCT00362648 | Completed | Phase 3 | Developing World Study for RotaTeq™ (V260-015)(COMPLETED) | March 2007 | March 2009 |
| NCT00370968 | Completed | Phase 2/Phase 3 | Zinc-ORS in Severe and Complicated Acute Diarrhea | September 2003 | December 2006 |
| NCT00374023 | Completed | N/A | A Study on Immunological Effect of Vitamin A and Zinc in a Placebo Controlled 4 Cell Trial | July 1, 1993 | November 30, 1995 |
| NCT00388921 | Completed | N/A | High/Low Dose Vit A in Diarrhea/ALRI in Severe PEM | October 2005 | December 31, 2007 |
| NCT00397150 | Completed | N/A | PROMISE EBF: Safety and Efficacy of Exclusive Breastfeeding Promotion in the Era of HIV in Sub-Saharan Africa | November 2006 | April 2011 |
| NCT00419133 | Completed | Phase 2 | Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccine | June 2007 | August 2007 |
| NCT00435526 | Completed | Phase 1 | Efficacy of Anti-CFA/I and CfaE Bovine Milk Immunoglobulin Against Challenge With H10407 ETEC Expressing CFA/I | March 2006 | October 2006 |
| NCT00439660 | Completed | Phase 1/Phase 2 | Dose Escalation Study to Evaluate Oral Rotavirus Vaccine 116E Live Attenuated in Healthy Infants 8 to 20 Weeks Old | December 2006 | November 2008 |
| NCT00463190 | Completed | Phase 4 | Effect of Probiotics (Bio-Three) in Children's Enterocolitis | February 2006 | November 2007 |
| NCT00468728 | Completed | Phase 3 | PAR-101/OPT-80 Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) | October 4, 2006 | December 11, 2009 |
| NCT00470158 | Completed | Phase 4 | Delivery of Iron and Zinc Supplements: Evaluation of Interaction Effect on Biochemical and Clinical Outcomes | May 2007 | February 2008 |
| NCT00490932 | Completed | Phase 4 | New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Diarrhea Management- Surveillance Study for Adverse Effects | March 2005 | April 2007 |
| NCT00495690 | Completed | Phase 3 | Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease | November 2004 | May 2008 |
| NCT06403358 | Completed | Study for Evaluation of Probiotics in the Re-equilibration of the Intestinal Microbiota, in Paediatric Age | November 28, 2022 | January 30, 2024 | |
| NCT00002121 | Completed | Phase 1 | Diethylhomospermine (DEHSPM) for Refractory AIDS-Related Diarrhea | ||
| NCT00002252 | Completed | N/A | A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea | ||
| NCT00002253 | Completed | N/A | A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study. | ||
| NCT00002408 | Completed | Phase 3 | A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Orally Administered SP-303 for the Treatment of Diarrhea in Acquired Immunodeficiency Syndrome (AIDS) Patients | ||
| NCT00003057 | Completed | Phase 3 | Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer | March 26, 1997 | |
| NCT00003825 | Completed | Phase 3 | Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy | June 1999 | |
| NCT00017810 | Completed | Phase 2 | The Healthy Life Choices Project in HIV-Positive Patients | September 1996 | March 2003 |
| NCT02324075 | Completed | N/A | Using Behaviour Change Messaging to Improve Communal Toilets in Dhaka, Bangladesh | December 2014 | November 2015 |
| NCT02340481 | Completed | Phase 3 | Efficacy and Safety Study of Loperamide Hydrochloride/Simethicone Chewable Tablet in Treatment of Acute Diarrhea With Abdominal Discomfort and Flatulence | July 2005 | May 2006 |
| NCT02362932 | Completed | N/A | The Effect of an Urban Sanitation Intervention on Child Health | February 2015 | September 5, 2018 |
| NCT02374580 | Completed | Partnership and Dignity: a Mixed-methods Survey on Supporting and Retaining Uganda's Village Health Teams | February 2015 | May 2015 | |
| NCT02385773 | Completed | N/A | Impact of the Nutritional Product PTM202 on Acute and Long-Term Recovery From Childhood Diarrheal Disease | March 2015 | July 2016 |
| NCT02396407 | Completed | N/A | Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health | January 2015 | May 2016 |
| NCT02424812 | Completed | N/A | Evaluation Of The Unilever Lifebuoy School-Based Handwashing Campaign (School Of 5) In Rural Bihar, India | February 2016 | February 27, 2017 |
| NCT02428647 | Completed | N/A | Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation | September 2015 | July 2017 |
| NCT02436057 | Completed | N/A | Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform | July 2014 | December 2015 |
| NCT02462590 | Completed | Phase 4 | Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial | June 2015 | November 17, 2020 |
| NCT02464098 | Completed | Epidemiology of Diarrheal Diseases in Pediatric Oncology Patients | November 19, 2015 | December 31, 2021 | |
| NCT02473796 | Completed | N/A | Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT | January 2004 | April 2010 |
| NCT02498418 | Completed | Phase 3 | Study Comparing Rifaximin With Xifaxan 200 mg in Traveler's Diarrhea | January 6, 2016 | February 28, 2017 |
| NCT02530216 | Completed | N/A | Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes | April 10, 2017 | February 7, 2018 |
| NCT02541695 | Completed | N/A | Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli | September 2015 | January 2017 |
| NCT02556996 | Completed | Phase 3 | Efficacy of an Oral, Killed Enterotoxigenic Escherichia Coli Vaccine in Prevention of Diarrhea in Egyptian Infants and Young Children | October 1998 | April 2002 |
| NCT02606981 | Completed | N/A | Automatic Chlorination and Child Health in Urban Bangladesh | July 2015 | December 20, 2016 |
| NCT02607176 | Completed | Phase 4 | Heweizhixie capsuleTherapy on Patients With Diarrhea | October 2015 | April 2018 |
| NCT02645513 | Completed | N/A | Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi | January 2015 | February 2016 |
| NCT02694679 | Completed | N/A | Randomized Controlled Trial of Social Network Targeting in Honduras | June 2015 | January 2020 |
| NCT02748616 | Completed | Phase 4 | C. Difficile and Ursodiol | March 1, 2017 | January 31, 2020 |
| NCT02779010 | Completed | N/A | Impact of Hand Washing and WASH Educational Intervention on Under-five Diarrheal Diseases | February 2015 | July 2015 |
| NCT02819960 | Completed | Phase 3 | Prevention of Irinotecan Induced Diarrhea by Probiotics | March 2016 | November 2022 |
| NCT02864433 | Completed | Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control Efforts | October 2012 | March 2017 | |
| NCT02870491 | Completed | N/A | Working With Community Health Workers to Increase ORS Use in Uganda | August 2016 | January 2019 |
| NCT02871908 | Completed | Phase 4 | Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial | December 2016 | March 2018 |
| NCT02875249 | Completed | Intestinal Microbiome and Chemotherapy | November 2010 | January 2014 | |
| NCT02928341 | Completed | N/A | Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo | October 2016 | December 31, 2021 |
| NCT02934178 | Completed | Phase 1 | Shigella WRSS1 Vaccine Trial in Bangladesh | February 23, 2017 | January 10, 2018 |
| NCT02944617 | Completed | N/A | Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor | November 11, 2016 | December 19, 2021 |
| NCT02949089 | Completed | Phase 1 | ACH04 to Assess the Safety and Tolerability in Healthy Adults Subjects | January 2013 | September 2014 |
| NCT02950142 | Completed | N/A | Evidence-based Laboratory Test Order Sets in Primary Care | December 1, 2017 | August 1, 2019 |
| NCT03005821 | Completed | N/A | Chinese Pediatric Massage on Children With Acute Diarrhea: a Randomized Sham Massage Controlled Trial | January 2017 | October 25, 2019 |
| NCT03021434 | Completed | N/A | Trial of Low-cost Microbiological Water Test Kits | January 2017 | May 25, 2017 |
| NCT03078842 | Completed | N/A | Zinc Dosing Trial - Does Dose Reduction Reduce Side Effects But Retain Efficacy in Diarrhoea Management | January 23, 2017 | February 1, 2020 |
| NCT03130114 | Completed | Phase 3 | Antibiotics for Children With Severe Diarrhoea | May 13, 2017 | January 15, 2020 |
| NCT03154229 | Completed | N/A | Evaluation of a mHealth Platform for Diarrheal Disease Decision-support | March 11, 2018 | September 23, 2018 |
| NCT03174015 | Completed | N/A | Sanitation Demand Creation in Peri-Urban Slums of Lusaka, Zambia | August 7, 2017 | March 5, 2018 |
| NCT03176914 | Completed | N/A | Testing the Effectiveness of a Modified Community Model in Improving Child Health Outcomes in Mashonaland East, Zimbabwe | January 19, 2017 | December 31, 2018 |
| NCT03234452 | Completed | N/A | Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects. | March 23, 2016 | April 18, 2017 |
| NCT03280771 | Completed | N/A | The Hope Soap Study: a Hand-washing Intervention Among Children in South Africa | September 1, 2014 | December 15, 2015 |
| NCT03321578 | Completed | Hospital Onset Diarrhoea Investigation | January 2016 | August 2016 | |
| NCT03376698 | Completed | Phase 2 | Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease | June 15, 2017 | April 1, 2022 |
| NCT03388268 | Completed | Phase 4 | TOX NEG Trial: Clostridium Difficile Diagnosis and Treatment | December 29, 2017 | January 31, 2021 |
| NCT03404674 | Completed | Phase 1 | Dose Escalating Study of a Prototype CS6 Subunit Vaccine With a Modified Heat-labile Enterotoxin From Enterotoxigenic Escherichia Coli (ETEC) | January 16, 2018 | March 26, 2019 |
| NCT03406793 | Completed | N/A | Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth | February 20, 2018 | January 12, 2020 |
| NCT03407534 | Completed | Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating | November 2015 | February 15, 2022 | |
| NCT03423615 | Completed | N/A | Lay Fieldworker Led School Health Program for Rural Primary Schools | February 1, 2012 | December 31, 2016 |
| NCT03463512 | Completed | Phase 3 | Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea | March 29, 2018 | September 10, 2018 |
| NCT03468114 | Completed | N/A | The Safe Start Trial - Kisumu, Kenya | March 26, 2018 | June 22, 2019 |
| NCT03536286 | Completed | N/A | Asili Evaluation in the Democratic Republic of Congo | August 4, 2016 | July 31, 2018 |
| NCT03565393 | Completed | Phase 1/Phase 2 | Tolerability and Acceptability of Fibersol-2 in Children | March 19, 2018 | March 31, 2019 |
| NCT03576183 | Completed | Phase 2 | Study Confirming A Human Challenge Model and Investigating The Safety Of VLA1701 | June 4, 2018 | November 30, 2018 |
| NCT03587389 | Completed | Phase 4 | Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam | March 19, 2019 | August 8, 2022 |
| NCT03596827 | Completed | N/A | The Protective Immune Response to Attenuated Enterotoxigenic Escherichia Coli Infection | September 26, 2018 | February 28, 2019 |
| NCT03602053 | Completed | Phase 2/Phase 3 | Study of BBIL's ROTAVAC® and ROTAVAC 5CM Vaccines in Zambia | January 22, 2019 | October 4, 2019 |
| NCT03656198 | Completed | Phase 4 | Non-specific Effects of Rabies Vaccine | August 29, 2018 | July 27, 2020 |
| NCT03703336 | Completed | Phase 3 | Phase III Study of Liquid Formulation of ROTAVIN | March 16, 2019 | January 8, 2020 |
| NCT03709368 | Completed | N/A | Software Interventions for Improving Hand Washing and Sanitation in Rural Tanzania: an Impact Evaluation | April 23, 2018 | May 31, 2021 |
| NCT03722511 | Completed | Phase 2 | Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs | December 6, 2018 | May 18, 2021 |
| NCT03729219 | Completed | Phase 2 | Prevention of Diarrheal Disease Due to Infection With Enterotoxigenic E. Coli (ETEC) | June 12, 2017 | April 15, 2019 |
| NCT03854929 | Completed | Phase 4 | Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery | December 11, 2019 | July 12, 2022 |
| NCT03869333 | Completed | Phase 1 | Dose Escalating Study of Intramuscular Invaplex[AR-DETOX] | March 18, 2019 | June 12, 2020 |
| NCT03874143 | Completed | N/A | Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care | March 1, 2016 | October 1, 2016 |
| NCT03972618 | Completed | N/A | Evaluation of the Efficacy of Sawyer Point One Filters in Schools and Homes in the Dominican Republic | September 22, 2018 | April 15, 2019 |
| NCT04003181 | Completed | N/A | The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon | September 28, 2017 | May 26, 2021 |
| NCT04008134 | Completed | N/A | Cholera-Hospital-Based-Intervention-for-7-days | December 4, 2016 | April 26, 2019 |
| NCT04014816 | Completed | Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients | January 1, 2015 | July 1, 2015 | |
| NCT04020965 | Completed | N/A | Drinking Water Chlorination and Child Survival in Rural Kenya | July 26, 2019 | May 26, 2021 |
| NCT04042454 | Completed | N/A | To Assess the Safety and Tolerance of Infant Formula With Locust Bean Gum in Infants With Regurgitation | December 10, 2019 | May 23, 2023 |
| NCT04065529 | Completed | Phase 3 | Clinical Trial in Children Between 3 Months and 14 Years Old to Evaluate the Efficacy and Safety of Gelatin Tannate in the Treatment of Acute Diarrhea (INDIGO) | September 11, 2019 | June 11, 2020 |
| NCT04144491 | Completed | N/A | Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda | September 16, 2019 | May 30, 2020 |
| NCT04312906 | Completed | A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa | September 14, 2020 | November 30, 2021 | |
| NCT04393909 | Completed | N/A | Improving Safety of Diagnosis and Therapy in the Inpatient Setting | July 1, 2019 | December 30, 2021 |
| NCT04491799 | Completed | Fecal Calprotectin Level in Patients With Nosocomial Diarrhea | February 1, 2019 | October 30, 2020 | |
| NCT04554979 | Completed | COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience | June 1, 2020 | July 15, 2020 | |
| NCT04560595 | Completed | N/A | Remote Guided Caffeine Reduction | September 10, 2020 | October 1, 2023 |
| NCT04580212 | Completed | N/A | Poultry Management and Child Diarrhea in Uganda | September 1, 2019 | August 25, 2021 |
| NCT04811339 | Completed | Phase 4 | Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol) | October 27, 2020 | August 15, 2021 |
| NCT05024890 | Completed | N/A | The Impact of a School-based WASH Intervention on Child Health and School Attendance in Addis Ababa, Ethiopia | November 2, 2021 | August 10, 2022 |
| NCT05091775 | Completed | Phase 1/Phase 2 | The Efficacy of Asacol (Mesalazine) Suppository on the Treatment of Diarrhea-Induced Acute Fissure | June 1, 2020 | January 10, 2021 |
| NCT05207618 | Completed | N/A | Utility of the Administration of Chesnut and Quebracho Extract for Irritable Bowel Syndrome Diarrhea Predominant | September 21, 2021 | April 20, 2022 |
| NCT05247333 | Completed | N/A | Implementation of a Minor Ailment Service in Community Pharmacy Practice | October 1, 2020 | September 30, 2023 |
| NCT05328037 | Completed | Study on the Association Between Vitamin C Deficiency and Diarrhea in Children | April 25, 2022 | March 31, 2024 | |
| NCT05439772 | Completed | Phase 4 | Examining the Effect of Ondansetron on Bowel Prep Success | January 1, 2021 | July 1, 2023 |
| NCT05473546 | Completed | Diarrhea and Stipsis in Critically Ill Patients (NUTRITI) | October 11, 2019 | July 22, 2022 | |
| NCT05816681 | Completed | Phase 1 | Assessment of Elemental Impurities Level After Multiple Administration of DWJ1230 or DWB2001 in Subjects With Functional Diarrhea or Irritable Bowel Syndrome With Predominant Diarrhea. | August 22, 2022 | April 10, 2023 |
| NCT05900752 | Completed | N/A | A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients | June 19, 2023 | July 16, 2023 |
| NCT05974657 | Completed | N/A | Effectiveness and Safety of Lactobacillus Acidophilus LA85 in Preventing Antibiotic-Associated Diarrhea | August 31, 2021 | September 13, 2022 |
| NCT06125626 | Completed | Phase 2 | Prevention of Traveler's Diarrhea | July 10, 2023 | October 10, 2023 |
| NCT06283784 | Completed | N/A | Study To Evaluate The Efficacy of a Proprietary Mix of Live Probiotics In The Prophylaxis Of Diarrhea In Adult Patients | September 5, 2021 | May 18, 2022 |
| NCT06285851 | Completed | N/A | A Novel Iron Supplement for Athletes: Phase I | November 23, 2023 | December 12, 2023 |
| NCT06378424 | Completed | N/A | The Effectiveness of Local Dry Cold, Hot and Vibration Applications in Peripheral Intravenous Catheterization | March 22, 2023 | August 23, 2023 |
| NCT00002088 | Completed | Phase 2 | Treatment of Patients With Human Immunodeficiency Virus (HIV)-Related Chronic Diarrhea With Saccharomyces Boulardii or Placebo: A Double Blind Trial | ||
| NCT00510679 | Completed | N/A | Study of Post-Training Supports for Health Workers in Benin | July 1999 | October 2004 |
| NCT00512824 | Completed | N/A | Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children | August 2007 | September 2008 |
| NCT00516659 | Completed | Phase 2 | ETEC Logistics Trial (TREK) | May 2006 | December 2007 |
| NCT00530829 | Completed | Phase 3 | Impact of Home Zinc Treatment for Acute Diarrhea in Children | October 2007 | April 2009 |
| NCT00560222 | Completed | Phase 3 | Randomized, Controlled Trial - Lactoferrin Prevention of Diarrhea in Children | February 2008 | October 2011 |
| NCT00683982 | Completed | N/A | Use of Nitazoxanide and Probiotics in Acute Diarrhea Secondary to Rotavirus | August 2007 | May 2008 |
| NCT00685607 | Completed | Phase 4 | Study to Determine the Best Way to Measure How Quickly the Drug Can Give Relief From Sudden Diarrhea | October 2008 | October 2008 |
| NCT00705445 | Completed | Phase 2/Phase 3 | Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intestinal Mucosal Integrity and Growth Among Children of Pakistan | November 2008 | July 2012 |
| NCT00709410 | Completed | N/A | Mass Oral Cholera Vaccination in Zanzibar | January 2009 | December 2011 |
| NCT00713102 | Completed | Surgical and Medical Emergencies on Board of European Aircraft Carriers | January 2008 | August 2008 | |
| NCT00717730 | Completed | Phase 2 | Folic Acid and Vitamin B12 in Young Indian Children | January 2010 | September 2011 |
| NCT00731497 | Completed | Phase 3 | Solar Water Disinfection Intervention Trial in Bolivia | September 2004 | June 2006 |
| NCT00736567 | Completed | Evaluation of a Diagnostic Enteric Card for Management of Diarrhea | May 2008 | May 2009 | |
| NCT00737412 | Completed | Phase 3 | Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults | April 2008 | January 2010 |
| NCT00741637 | Completed | Phase 2 | Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults | July 2010 | June 2011 |
| NCT00742469 | Completed | Phase 3 | Rifaximin for Prevention of Travellers' Diarrhea | June 2005 | April 2007 |
| NCT00748215 | Completed | Phase 2 | Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan | February 4, 2009 | August 12, 2014 |
| NCT00760851 | Completed | Phase 3 | Yogurt Study in Children 2-4 Years Old Attending Daycare | September 2008 | July 2010 |
| NCT00763399 | Completed | Phase 4 | Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation | October 2008 | May 2010 |
| NCT00772343 | Completed | Phase 2 | Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection | February 2009 | June 2012 |
| NCT00794924 | Completed | N/A | Probiotics and Hospital Outcome in the Elderly | February 2004 | January 2005 |
| NCT00807326 | Completed | Phase 4 | A Comparison of Three Medications to Treat Diarrhea in Adults. | November 2008 | November 2009 |
| NCT00844493 | Completed | Phase 1 | Low-dose Challenge Model With Enterotoxigenic E Coli | February 2009 | June 2013 |
| NCT00846794 | Completed | AcuGraph and Digestive Symptoms | February 2009 | March 2010 | |
| NCT00849628 | Completed | Use of Drugs and Constipation in Nursing Homes | June 2008 | February 2010 | |
| NCT00891371 | Completed | Phase 2/Phase 3 | Lanreotide Autogel in the Symptomatic Treatment of Refractory Diarrhea | July 2009 | August 2013 |
| NCT00911612 | Completed | Phase 2 | Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)? | January 2009 | May 2009 |
| NCT00914225 | Completed | Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya | September 2009 | December 2011 | |
| NCT00942812 | Completed | Phase 4 | Community Based Intervention and Evaluation of the Impact of Social Marketing of a Diarrhea Management Pack | July 2009 | September 2010 |
| NCT00944359 | Completed | N/A | Impact of Preventive and Therapeutic Zinc Supplementation Programs Among Young Children | December 2010 | February 2012 |
| NCT00952952 | Completed | Phase 2/Phase 3 | Trial of Mesalamine for the Treatment of Active Microscopic Colitis | February 2007 | November 2007 |
| NCT00967551 | Completed | Phase 3 | Micronutrient Sprinkles in a Daycare Center | July 2009 | July 2012 |
| NCT00981877 | Completed | N/A | Probiotics in the Management of Acute Rotavirus Diarrhea in Bolivian Children | July 2007 | March 2008 |
| NCT01025583 | Completed | Phase 2/Phase 3 | Oral Rehydration Solution With Zinc and Prebiotics in Acute Diarrhea | November 2007 | March 2008 |
| NCT01046656 | Completed | Phase 3 | L Reuteri for the Prevention of Nosocomial Diarrhea | December 2009 | July 2011 |
| NCT01050465 | Completed | N/A | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use | May 2009 | December 2010 |
| NCT01060748 | Completed | Phase 2 | Safety and Efficacy Study of a Vaccine Against Enterotoxigenic Escherichia Coli (ETEC) to Prevent Moderate to Severe Diarrhea | March 2010 | October 2010 |
| NCT01067781 | Completed | Phase 2 | Safety and Immunogenicity Study of Traveler's Diarrhea Vaccine Patch | February 2010 | March 2012 |
| NCT01072110 | Completed | Confocal Laser Endomicroscopy (CLE) in Patients With Diarrhea | February 2010 | February 2014 | |
| NCT01073033 | Completed | N/A | Oral Supplement for Pregnant and Lactating Mothers | April 2010 | August 2012 |
| NCT01080716 | Completed | Phase 1/Phase 2 | Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate | May 2010 | December 2011 |
| NCT01082107 | Completed | N/A | Solar Disinfection of Drinking Water | October 2006 | August 2009 |
| NCT01085591 | Completed | Phase 2 | Study of CB-183,315 in Participants With Clostridium Difficile Infection | April 1, 2010 | May 13, 2011 |
| NCT01090843 | Completed | N/A | Video Capsule Endoscopy (VCE) Comparison Study | April 2010 | October 2011 |
| NCT01094041 | Completed | N/A | Gluten Intolerance in Patients With Diarrhea Predominant Irritable Bowel Syndrome | February 2010 | January 2013 |
| NCT01116908 | Completed | N/A | Safe Drinking Water For Households With Infants Born to HIV-Positive Mothers Pilot Study | April 2010 | August 2011 |
| NCT01133808 | Completed | Effectiveness of Rotavirus Immunization in Nicaragua | January 2010 | January 2011 | |
| NCT01153854 | Completed | Phase 3 | Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico | January 2007 | December 2009 |
| NCT01164215 | Completed | Phase 1 | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy | February 2010 | September 2013 |
| NCT01166815 | Completed | Phase 2/Phase 3 | Zinc Supplementation to Reduce Diarrhea Rates in Adults in Western Kenya. | July 2007 | January 2008 |
| NCT01198145 | Completed | Phase 3 | Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy | April 2011 | July 15, 2017 |
| NCT01198587 | Completed | N/A | Oral Zinc for the Treatment of Acute Diarrhea in US Children | November 2010 | June 2015 |
| NCT01225042 | Completed | N/A | The Effect of Probiotics on E. Coli Gastroenteritis | October 2010 | April 2011 |
| NCT01230957 | Completed | Phase 2 | Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults | October 2010 | March 2013 |
| NCT01269554 | Completed | Etiology of Diarrhea in Guinea-Bissau and in Finland | November 2010 | July 2015 | |
| NCT01306097 | Completed | N/A | Zinc Supplementation and Severe and Recurrent Diarrhea | January 2009 | May 2010 |
| NCT01326338 | Completed | Phase 3 | Nitazoxanide for the Treatment of Prolonged Diarrhea in Children | March 2005 | May 2006 |
| NCT01371656 | Completed | Phase 3 | Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation | September 2011 | June 2017 |
| NCT01375907 | Completed | Phase 1 | Safety Study of a Rotavirus Vaccine (Rotavin-M1) Among Healthy Adults | August 2009 | October 2009 |
| NCT01377571 | Completed | Phase 2 | A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy Infants | October 2009 | April 2010 |
| NCT01401023 | Completed | N/A | Pharmacokinetics and Safety of Tigecycline in the Treatment of Clostridium Difficile Associated Diarrhea (CDAD) | July 2011 | July 2013 |
| NCT01425073 | Completed | N/A | Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya | February 2012 | October 2013 |
| NCT01438645 | Completed | N/A | ScopeGuide-assisted Colonoscopy Versus Conventional Colonoscopy | September 2011 | December 2012 |
| NCT01467037 | Completed | Vaccine Effectiveness of RV1 in a Naïve Population | February 2012 | December 2014 | |
| NCT01467570 | Completed | Phase 4 | Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis | June 2009 | December 2011 |
| NCT01476683 | Completed | Phase 1 | Study to Compare the Pharmacokinetics Profiles of Four Racecadotril Products | December 2011 | December 2011 |
| NCT01480947 | Completed | Phase 4 | The Treatment Effect of Bio-Three on Children With Enteritis | February 2009 | December 2010 |
| NCT01482208 | Completed | Clinical Evaluation of Ultrasonic Hydration Monitor for Infants | November 2011 | October 2012 | |
| NCT01502969 | Completed | Phase 2/Phase 3 | Safety and Immunogenicity Assessment of Rotavin-M1 in Vietnamese Children | May 2010 | October 2011 |
| NCT01531218 | Completed | Phase 3 | Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea | March 2012 | December 2013 |
| NCT01538953 | Completed | N/A | Pakistan Flocculent Health Outcome Study | March 2003 | January 2004 |
| NCT01543451 | Completed | Phase 2 | Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea | February 2012 | October 2013 |
| NCT01559636 | Completed | N/A | Diarrhea and Bivalent Oral Polio Vaccine Immunity | August 2012 | October 2013 |
| NCT01637389 | Completed | N/A | Evaluation of Safe-Water Programs in Baja California Sur, Mexico | July 2009 | December 2010 |
| NCT01657032 | Completed | Phase 4 | Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis | August 2010 | October 2012 |
| NCT01704105 | Completed | N/A | WASH Benefits Kenya | November 2012 | July 2016 |
| NCT01709266 | Completed | N/A | The Effect of Probiotics on E. Coli-induced Gastroenteritis | August 2012 | November 2012 |
| NCT01717534 | Completed | N/A | Children Immune Functions | October 2012 | July 2013 |
| NCT01726751 | Completed | Phase 1/Phase 2 | Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome | August 2005 | April 2014 |
| NCT01731392 | Completed | N/A | Children Immune Functions(2) | November 2012 | June 2013 |
| NCT01739231 | Completed | Phase 1/Phase 2 | Live Attenuated ETEC Vaccine ACE527 With and Without dmLT Adjuvant in Adults | September 2012 | January 2014 |
| NCT01787058 | Completed | Evaluation of the Dubai Cares WASH in School Initiative | January 2013 | June 2014 | |
| NCT01791608 | Completed | Phase 4 | Zinc Sulphate vs. Zinc Amino Acid Chelate | March 2012 | November 2012 |
| NCT01800396 | Completed | N/A | Milk Ingredients and Resistance Against E-coli-induced GastroEnteritis (MIRAGE) | February 2013 | May 2013 |
| NCT01813071 | Completed | N/A | Safety Study of Live Attenuated Oral Shigella (WRSS1) Vaccine in Bangladeshi Adults and Children | August 2013 | April 2016 |
| NCT01822028 | Completed | Phase 1 | Two Period / Two Treatment Cross-over to Assess the Effect of Florastor® on Gastrointestinal Tolerability, Safety, and PK in Healthy Subjects Receiving Zavesca® | March 2013 | August 2013 |
| NCT01823939 | Completed | Phase 1 | PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera | May 2013 | December 2014 |
| NCT01832636 | Completed | Phase 3 | Intervention and Mechanisms of Alanyl-Glutamine for Inflammation, Nutrition, and Enteropathy | October 2013 | December 2015 |
| NCT01836731 | Completed | N/A | Impact Evaluation of Community-Based Health Programs in Rwanda | April 2013 | June 30, 2017 |
| NCT01837940 | Completed | Phase 3 | Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population | April 2013 | September 2013 |
| NCT01839721 | Completed | Phase 3 | Impact of Probiotics BIFILACT® on Diarrhea in Patients Treated With Pelvic Radiation | December 2006 | December 2010 |
| NCT01849107 | Completed | N/A | Plasma Citrulline: A Marker for Monitoring & Quantifying Radiation-Induced Small Bowel Toxicity | April 2013 | December 2014 |
| NCT01870635 | Completed | Phase 4 | Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in EDs in Pakistan | May 2014 | February 3, 2017 |
| NCT01870648 | Completed | Phase 4 | Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in EDs in Pakistan | May 2014 | December 2017 |
| NCT01900912 | Completed | N/A | Evaluating the Impact of Community Led Total Sanitation Programs in Mali | January 2011 | December 2013 |
| NCT01960725 | Completed | Phase 4 | An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq) | February 2014 | May 2016 |
| NCT01968408 | Completed | Phase 3 | Lactobacillus Reuteri DSM 17938 in Preventing Nosocomial Diarrhea in Children | September 2012 | February 2015 |
| NCT01992497 | Completed | N/A | Cesarean Section Study | December 2013 | December 2019 |
| NCT02047162 | Completed | N/A | Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan | May 2014 | September 2014 |
| NCT02057198 | Completed | Phase 4 | Impact of Oral Antibiotic Treatment on C. Difficile | June 10, 2014 | June 27, 2017 |
| NCT02118402 | Completed | N/A | Iron and Prebiotics Fortification in Kenyan Infants | July 2014 | December 2015 |
| NCT02143908 | Completed | N/A | Lysine Trial in Adults With Diarrhoea | December 2005 | December 2006 |
| NCT02146053 | Completed | Early Phase 1 | Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron. | March 2004 | December 2004 |
| NCT02197780 | Completed | Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD | September 2014 | April 2017 | |
| NCT02216708 | Completed | Phase 2 | Slow Versus Rapid Rehydration of Severely Malnourished Children | May 2011 | December 2013 |
| NCT02245139 | Completed | Surveillance Study of Acute Gastroenteritis in Hospitalized Children | July 1, 2014 | December 15, 2014 | |
| NCT02280044 | Completed | Phase 2/Phase 3 | Efficacy of Rifaximin in Preventing Campylobacteriosis | October 2014 | August 9, 2016 |
| NCT06149715 | Enrolling by invitation | N/A | Water Filter Study in Ciudad Victoria | January 20, 2024 | February 2025 |
| NCT04672577 | Not yet recruiting | Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria | January 30, 2021 | December 31, 2025 | |
| NCT06333795 | Not yet recruiting | N/A | Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic Sclerosis | April 1, 2024 | December 31, 2025 |
| NCT05663775 | Not yet recruiting | Phase 2 | Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) | December 2024 | October 2025 |
| NCT04605783 | Recruiting | N/A | Trial to Evaluate Dietary Supplements to Maintain Gut Health During Travel | May 27, 2022 | December 31, 2024 |
| NCT04684849 | Recruiting | Assessment and Validation of Electronic Gas and Bloating Diary | September 10, 2020 | August 31, 2024 | |
| NCT06047821 | Recruiting | Enterics for Global Health (EFGH) | August 25, 2022 | May 31, 2025 | |
| NCT06003816 | Recruiting | N/A | Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI) | October 18, 2023 | November 2025 |
| NCT04826991 | Recruiting | N/A | Wells and Enteric Disease Transmission | July 1, 2021 | May 31, 2025 |
| NCT04038619 | Recruiting | Phase 1 | Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients | February 1, 2021 | December 31, 2025 |
| NCT05750186 | Recruiting | N/A | The Effect of Abdominal Massage Applied After Surgery | October 1, 2022 | August 1, 2023 |
| NCT04926545 | Recruiting | N/A | XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study) | July 16, 2021 | October 31, 2024 |
| NCT05766826 | Recruiting | N/A | Coupons for Safe Water Project | February 21, 2023 | October 1, 2026 |
| NCT05776914 | Recruiting | Phase 2 | Fecal Microbiota Transplantation for IBS | April 15, 2024 | September 2025 |
| NCT06019312 | Recruiting | N/A | L. Plantarum 299v and Gut Microbiome, Diarrhoea, and Clostridioides Difficile Infection in Colorectal Cancer Patients | August 1, 2023 | June 1, 2024 |
| NCT06080906 | Recruiting | Phase 2 | Phase II Clinical Trial of the Inactivated Rotavirus Vaccine | October 20, 2023 | June 17, 2025 |
| NCT03851835 | Recruiting | Phase 3 | Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis | September 4, 2019 | June 2024 |
| NCT06031025 | Recruiting | Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants. | May 20, 2022 | December 31, 2024 | |
| NCT05372068 | Recruiting | N/A | Cement flooRs AnD chiLd hEalth (CRADLE) | September 24, 2023 | September 2027 |
| NCT06152471 | Recruiting | Phase 3 | Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer | June 7, 2023 | March 31, 2025 |
| NCT05814042 | Recruiting | Phase 2/Phase 3 | Next Generation ORS: Controlled Trial Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea | August 21, 2023 | December 2024 |
| NCT05519254 | Recruiting | Phase 3 | Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae | March 10, 2023 | December 2026 |
| NCT06206707 | Recruiting | N/A | FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis | January 23, 2024 | March 31, 2025 |
| NCT06268717 | Recruiting | N/A | GI Alpha-Gal Study | October 17, 2023 | October 17, 2025 |
| NCT06318078 | Recruiting | N/A | Buikwe Electronic Community Health Information System Impact Study | December 1, 2023 | July 2024 |
| NCT03978949 | Recruiting | Phase 3 | Prevention of Radiotherapy Induced Enteropathy by Probiotics (PREP) | June 1, 2019 | August 31, 2024 |
| NCT00036517 | Terminated | Phase 1/Phase 2 | Safety Study of the Chemotherapy Modulator PHY906 in Patients With Advanced Colorectal Cancer | February 2002 | March 2003 |
| NCT00040391 | Terminated | Phase 2 | A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer | June 2002 | |
| NCT00217022 | Terminated | Phase 2/Phase 3 | Budesonide Versus Placebo for the Treatment of Lymphocytic Colitis | June 2003 | February 2008 |
| NCT01469338 | Terminated | Phase 2 | Cabazitaxel Plus Prednisone With Octreotide For Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel | July 2012 | November 2014 |
| NCT03394040 | Terminated | Point-of-Use Pathogen Identification Tool for Diarrhea | February 14, 2019 | December 23, 2019 | |
| NCT01143272 | Terminated | Phase 3 | Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea | June 2010 | October 2012 |
| NCT02381405 | Terminated | N/A | A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®)- for Maintaining Bowel Regularity in Patients With GI Toxicity From Any Combination of Therapy Including Tyrosine Kinase Inhibitors (TKI) | February 2015 | December 2015 |
| NCT01472211 | Terminated | Early Phase 1 | Water-based Zinc Intervention Trial in Zinc Deficient Children | September 2011 | September 2012 |
| NCT00444093 | Terminated | Phase 3 | Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium - | March 5, 2007 | February 29, 2008 |
| NCT00466635 | Terminated | Phase 3 | A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Difficile-associated Diarrhea | April 2007 | August 2007 |
| NCT01048567 | Terminated | Phase 2 | Efficacy and Safety of Lactobacillus Acidophilus/Rhamnosus Combination for the Prevention of Antibiotic-associated Diarrhea in the Elderly | September 2011 | October 2011 |
| NCT00006269 | Terminated | Phase 3 | Octreotide in the Prevention of Diarrhea in Patients Receiving Irinotecan for Metastatic Colon Cancer | December 1999 | |
| NCT03486587 | Terminated | Phase 2 | A Study Evaluating Bacillus Cereus in the Prevention of Afatinib-associated Diarrhea | April 15, 2018 | December 31, 2020 |
| NCT00624975 | Terminated | Phase 2 | Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants | November 2008 | July 2012 |
| NCT01823952 | Terminated | High Amylose Maize Starch for Treatment of Cholera | April 2013 | February 2014 | |
| NCT02991768 | Terminated | Phase 2 | Budesonide for Mycophenolic Acid-induced Diarrhea in Renal Transplant Recipients | January 27, 2017 | April 26, 2019 |
| NCT00937274 | Terminated | N/A | Antibacterial Treatment Against Diarrhea in Oral Rehydration Solution | August 2009 | January 2013 |
| NCT02707198 | Terminated | Phase 2 | Prevention of Clostridium Difficile-associated Diarrhea by Daily Intake of Kefir | November 2015 | May 10, 2019 |
| NCT02018653 | Terminated | N/A | CASAD for Severe Diarrhea in the Emergency Department | December 2013 | August 2014 |
| NCT04486326 | Terminated | Phase 4 | Crofelemer for Functional Diarrhea | August 20, 2020 | September 23, 2022 |
| NCT02182466 | Terminated | German Colon Capsule Registry | June 2014 | March 30, 2017 | |
| NCT02076438 | Terminated | N/A | Probiotics for Prevention of Antibiotic Associated Diarrhea and Clostridium Difficile Associated Disease | November 2015 | September 2016 |
| NCT00650637 | Terminated | Phase 3 | A Study to Determine Effective Prophylaxis and Treatment of Nelfinavir-Associated Diarrhea | January 2003 | August 2003 |
| NCT02534272 | Terminated | Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota | February 16, 2016 | March 29, 2019 | |
| NCT03990220 | Unknown status | A Nutritional Trial on Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda | July 1, 2019 | June 1, 2020 | |
| NCT02866097 | Unknown status | N/A | Integrated Community Case Management Study in Eastern Province, Zambia | March 2016 | September 2016 |
| NCT00534170 | Unknown status | Phase 3 | Randomized Controlled Field Trial of a Probiotics to Assess Its Role in Preventig Diarrhoea | June 2007 | January 2008 |
| NCT00536848 | Unknown status | Phase 2/Phase 3 | The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients | October 2007 | August 2008 |
| NCT00548054 | Unknown status | Phase 2 | Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants | December 2015 | December 2016 |
| NCT00506181 | Unknown status | Phase 3 | Probiotics: is it Really That Good? Cost-Effectiveness of Treating the in-Patient | July 2007 | July 2008 |
| NCT01739634 | Unknown status | Phase 1/Phase 2 | The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer | November 2012 | December 2013 |
| NCT01792739 | Unknown status | Phase 4 | Lactobacillus Preparation on the Incidence of Diarrhea | November 2010 | October 2013 |
| NCT02949882 | Unknown status | Phase 4 | Improving Bowel Habits of Elderly With Probiotics and Non-probiotics | April 2017 | August 2017 |
| NCT02977897 | Unknown status | Fecal Calprotectin Levels in Mycophenolate Mofetil Induced Diarrhea and Treatment With Octreotide | January 2017 | ||
| NCT01863303 | Unknown status | Epidemiological Study of Colorectal Cancer in WuHan | June 2012 | June 2018 | |
| NCT04368351 | Unknown status | Bacteriotherapy in the Treatment of COVID-19 | March 1, 2020 | July 31, 2020 | |
| NCT03208725 | Unknown status | Childhood Acute Illness and Nutrition Network | November 30, 2016 | October 31, 2020 | |
| NCT03265730 | Unknown status | Pediatric Antibiotic Associated Diarrhea | August 2016 | August 2018 | |
| NCT02016807 | Unknown status | ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial | January 2013 | January 2015 | |
| NCT01011322 | Unknown status | Phase 2 | A Study to Investigate the Efficacy of LT-02 in Patients With Mesalazine Refractory Ulcerative Colitis | December 2009 | February 2012 |
| NCT03357237 | Unknown status | N/A | EFFICACY AND SAFETY OF XILOGLUCAN IN ACUTE GASTROENTERITIS IN CHILDREN | December 1, 2017 | July 30, 2018 |
| NCT02177799 | Unknown status | Surveillance Study of Acute Gastroenteritis in Hospitalized Children in Rural Area in Lebanon | July 2014 | ||
| NCT02231047 | Unknown status | N/A | 64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings | January 2015 | August 2019 |
| NCT04874883 | Unknown status | Phase 4 | Effect of the Use of Symbiotics in Patients With Colon Cancer | December 1, 2019 | December 1, 2022 |
| NCT02441426 | Unknown status | Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development | November 2008 | April 2017 | |
| NCT01278017 | Unknown status | Phase 4 | The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis | August 2010 | July 2012 |
| NCT02441699 | Unknown status | Assessing the Health Impact of a Combined Water and Sanitation Intervention in Rural Odisha, India | April 2015 | December 2019 | |
| NCT04885049 | Unknown status | N/A | Comparing the Efficacy of Anti-secretory Versus Oral Immunoglobulins for Reducing the Episodes of Diarrhea in Children | September 1, 2021 | February 1, 2022 |
| NCT03598010 | Unknown status | N/A | Safety, Tolerability and Preliminary Efficacy of Lenodiar Pediatric in Diarrhea | October 2019 | March 2021 |
| NCT01376336 | Unknown status | N/A | Trial of Safe Water Storage Among People Living With HIV | August 2011 | August 2013 |
| NCT01382199 | Unknown status | Phase 3 | Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adult Patients | September 2011 | March 2014 |
| NCT05050825 | Unknown status | N/A | Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal | May 3, 2021 | December 15, 2021 |
| NCT02536144 | Unknown status | N/A | The Clinical Application of MCCES in Examination of Human Colon | August 2015 | September 2015 |
| NCT05052489 | Unknown status | Registry and Clinical Observation of Children With Diarrhoeal Disease | September 2021 | May 2022 | |
| NCT02601742 | Unknown status | Phase 3 | Effectiveness of Oral Rehydration Therapy Supplemented With Zinc in the Management of Diarrhea Acute | November 2015 | November 2016 |
| NCT05123378 | Unknown status | N/A | Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality | May 1, 2018 | August 1, 2022 |
| NCT01501305 | Unknown status | Phase 1/Phase 2 | Influence of Carob and Probiotics on Acute Diarrhea in Children | January 2012 | February 2013 |
| NCT03778125 | Unknown status | Multidrug Resistant Shigella Infection in Bangladesh | December 13, 2018 | January 31, 2020 | |
| NCT01590095 | Unknown status | N/A | WASH Benefits Bangladesh | May 2012 | December 2022 |
| NCT01644097 | Withdrawn | Phase 2 | Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy | November 2012 | |
| NCT04713202 | Withdrawn | Phase 2 | Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl | March 3, 2021 | February 2024 |
| NCT01114113 | Withdrawn | N/A | Assessment of Gastric Emptying Speed in Patients Who Experience Diarrhea Following a Trigger Meal | April 2010 | January 2011 |
| NCT00124865 | Withdrawn | Phase 1 | Intranasal Recombinant Flagellin Subunit Campylobacter Vaccine (rFla-MBP) Dose-Ranging Study | July 2005 | November 2006 |
| NCT03489265 | Withdrawn | Phase 2 | Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence | April 2019 | March 2020 |
| NCT01473290 | Withdrawn | Phase 3 | Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy | ||
| NCT02597556 | Withdrawn | Phase 4 | The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children | February 2016 | May 2016 |
| NCT00090688 | Withdrawn | Phase 1 | Phase 1 meCS6 + LT(R192G) Vaccine Study | August 2004 | |
| NCT04313088 | Withdrawn | Phase 2/Phase 3 | Investigation of Eluxadoline for Diabetic Diarrhea | July 1, 2022 | December 2024 |
- Disase is a (Disease Ontology)
- DOID:77
- Cross Reference ID (Disease Ontology)
- ICD9CM:009.2
- Cross Reference ID (Disease Ontology)
- MESH:D004403
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154268000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0013369
- Disase Synonym (Disease Ontology)
- diarrhea of presumed infectious origin
- Disase Synonym (Disease Ontology)
- diarrhoea
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002014
- MeSH unique ID (MeSH (Medical Subject Headings))
- D003967