T-Cell Lymphoma

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Information
Disease name
T-Cell Lymphoma
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03792256 Active, not recruiting Phase 1 Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) April 11, 2019 June 30, 2025
NCT05442554 Active, not recruiting Phase 4 A Study of Brentuximab Vedotin Treatment in Chinese Adults With CD30-Positive Cutaneous T-Cell Lymphoma July 20, 2023 September 30, 2024
NCT04712864 Active, not recruiting Phase 1 Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma September 13, 2021 December 2025
NCT03952078 Active, not recruiting Phase 1 A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell Lymphoma May 3, 2019 April 30, 2026
NCT01181271 Completed Phase 2 Tandem Auto-Allo Transplant for Lymphoma August 2010 February 2016
NCT01553786 Completed Phase 2 Efficacy of a Treatment With CHOP and Lenalidomide in First Line in Angioimmunoblastic T-cell Lymphoma (AITL) November 2011 March 21, 2019
NCT01777152 Completed Phase 3 ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas January 31, 2013 October 2, 2020
NCT01871675 Completed Phase 1 Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies May 2013 June 2016
NCT00322985 Completed Phase 2 A Phase II Clinical Trial of Lenalidomide for T-cell Non-Hodgkin's Lymphoma June 2006 July 2014
NCT01902225 Completed Phase 1 Phase I Dose-finding and Preliminary Efficacy Study of the Istodax® in Combination With Doxil® for the Treatment of Adults With Relapsed or Refractory Cutaneous T-cell Lymphoma March 4, 2014 April 11, 2020
NCT01941680 Completed High Risk Adult T-cell Leukemia/Lymphoma (ATLL-HR) and Allogeneic Transplant October 31, 2013 March 2021
NCT02017613 Completed Phase 1 Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies November 2013 May 2016
NCT00001582 Completed Investigation of the Human Immune Response in Normal Subjects and Patients With Disorders of the Immune System and Cancer June 7, 1997 March 17, 2023
NCT02309580 Completed Phase 1 Study of Ibrutinib in Relapsed and Refractory T-cell Lymphoma January 2015 May 8, 2023
NCT00542919 Completed Phase 2 A Study for Patients With Non-Hodgkin's Lymphomas November 2007 February 27, 2018
NCT00161590 Completed Phase 1 Study of CHOP + Campath for T-Cell, Null Cell, or Natural Killer (NK)-Cell Lymphoma July 2004
NCT00959686 Completed Phase 2 Bendamustine in Patients With Refractory or Relapsed T-cell Lymphoma September 2009 February 2013
NCT02424045 Completed Phase 2 Bendamustine, Carboplatin and Dexamethasone (BCD) for Refractory or Relapsed Peripheral T-cell Lymphoma May 2015 September 2017
NCT02846935 Completed Early Phase 1 p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Refractory/Relapsed Lymphoid Malignancies April 25, 2017 January 22, 2018
NCT03734601 Completed Phase 2 Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation November 5, 2018 November 17, 2020
NCT06390319 Not yet recruiting Phase 2 Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) June 2024 December 2033
NCT05731375 Not yet recruiting Mitochondrial dysfUnction: a Key Player in Doxorubicin-induced Skeletal and Cardiac muscLE Damage April 2024 December 2025
NCT05983965 Not yet recruiting Phase 1 Study of Tazemetostat in Lymphoid Malignancies August 2024 December 2029
NCT05978141 Recruiting A Registry for People With T-cell Lymphoma July 27, 2023 July 27, 2030
NCT05886478 Recruiting A Study in Adults With Cutaneous T-cell Lymphoma (CTCL) Retreated With Brentuximab Vedotin February 8, 2024 June 30, 2024
NCT03829540 Recruiting Phase 1 CD4CAR for CD4+ Leukemia and Lymphoma July 9, 2020 December 2037
NCT04234048 Recruiting Phase 1 Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma December 18, 2023 November 2025
NCT04331119 Recruiting Phase 2 Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell Lymphomas July 23, 2020 July 31, 2027
NCT05665530 Recruiting Phase 1 A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib in Participants With R/R Hematologic Malignancies September 12, 2023 April 2025
NCT05075460 Recruiting Phase 3 Tucidinostat, Azacitidine Combined With CHOP Versus CHOP in Patients With Untreated Peripheral T-cell Lymphoma October 1, 2021 October 30, 2024
NCT05313243 Recruiting Phase 2 Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory T-cell Lymphoma July 10, 2023 July 30, 2028
NCT02588651 Recruiting Phase 2 A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL) June 17, 2016 June 15, 2027
NCT06224049 Recruiting Early Phase 1 Treatment of Relapsed or Refractory Epstein-Barr Virus Positive T-cell Lymphoma With hNeo-T December 1, 2023 June 30, 2026
NCT06131801 Recruiting Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution November 15, 2023 December 1, 2027
NCT02086591 Terminated Phase 2 A Phase II Study of Doxycycline in Relapsed NHL March 2014 November 2015
NCT00161239 Terminated N/A LAMPP Trial for Peripheral and Cutaneous T-Cell Lymphoma February 2005 October 2007
NCT00893516 Terminated Phase 2 CD4 in Combination With CHOP in Treating Non-cutaneous Peripheral TCell Lymphoma May 2007 December 2008
NCT01878708 Terminated Early Phase 1 A Pilot Study of Oncaspar® + Dexamethasone in Patients With Relapsed or Refractory T-Cell Lymphoma July 2013 February 2017
NCT05387226 Unknown status Phase 1 Intravenous Injection of Oncolytic Virus Injection (RT-01) in Patients With Relapsed or Refractory T-cell Lymphoma May 2022 December 2023
NCT04264078 Unknown status Early Phase 1 Anti-CD7 U-CAR-T Cell Therapy for T/NK Cell Hematologic Malignancies March 1, 2021 June 1, 2023
NCT03207789 Unknown status T-cell Brazil: Prospective Collection of Data in T-cell Lymphomas Patients January 1, 2015 December 31, 2020
NCT03021057 Unknown status Phase 2 Pembrolizumab for T/NK-cell lymphomasNK-cell Lymphomas December 1, 2016 December 2020
NCT01854112 Unknown status Helical Irradiation of Total Skin (HITS) for T Cell Lymphoma November 2012
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0012190