aspergillosis
Information
- Disease name
- aspergillosis
- Disease ID
- DOID:13564
- Description
- "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system." [url:http\://mycology.adelaide.edu.au/Mycoses/Opportunistic/Aspergillosis/, url:http\://www.mayoclinic.com/print/aspergillosis/DS00950/METHOD=print&DSECTION=all]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05045391 | Active, not recruiting | Pulmonary Aspergillosis in Tuberculosis Patients | January 1, 2020 | December 31, 2030 | |
| NCT00001810 | Completed | Phase 3 | An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections | April 1999 | October 2000 |
| NCT00001937 | Completed | Phase 3 | Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients | November 1999 | December 2000 |
| NCT00005668 | Completed | Phase 2 | A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma | November 2005 | |
| NCT00005912 | Completed | Phase 1 | Voriconazole to Prevent Systemic Fungal Infections in Children | June 2000 | January 2001 |
| NCT00036166 | Completed | Phase 2 | Study of FK463 for the Treatment of Invasive Aspergillosis | January 29, 1999 | January 31, 2002 |
| NCT00037206 | Completed | Phase 2/Phase 3 | A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome® for Treatment of Invasive Aspergillosis (IA). | May 2002 | February 2003 |
| NCT00001646 | Completed | Phase 3 | Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis | August 1997 | August 2000 |
| NCT00076869 | Completed | Phase 2 | MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) | January 2003 | August 2005 |
| NCT00082524 | Completed | Phase 2 | Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043) | April 2004 | July 2007 |
| NCT00159822 | Completed | Phase 2/Phase 3 | Voriconazole For Chronic Bronchopulmonary Aspergillosis | July 2005 | December 2008 |
| NCT00263315 | Completed | Phase 2/Phase 3 | Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis | January 2000 | May 2006 |
| NCT00361517 | Completed | Phase 3 | To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early | June 1, 2006 | June 30, 2009 |
| NCT00388167 | Completed | Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection | March 2004 | February 2008 | |
| NCT00412893 | Completed | Phase 3 | Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis | March 7, 2007 | March 28, 2013 |
| NCT05707156 | Completed | Prospective Observational Study on the Incidence of Opportunistic Fungal Infections | July 5, 2023 | January 5, 2024 | |
| NCT00473252 | Completed | Surveillance of Fungal Infections During Construction Activity | May 2006 | July 2009 | |
| NCT00531479 | Completed | Phase 3 | Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis | July 2008 | May 2011 |
| NCT00634049 | Completed | Phase 3 | Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi | April 22, 2008 | May 5, 2016 |
| NCT00647907 | Completed | Phase 4 | A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections | April 2003 | May 2004 |
| NCT00784368 | Completed | Phase 3 | A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection | January 2008 | May 2009 |
| NCT00854607 | Completed | An Observational Study of Fungal Biomarkers (MK-0000-089) | March 2009 | August 2011 | |
| NCT00940017 | Completed | Phase 4 | A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects | September 2008 | October 2008 |
| NCT01165320 | Completed | Phase 2 | A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074) | July 6, 2010 | September 17, 2013 |
| NCT05065658 | Completed | Posaconazole Prophylaxis for CAPA Prevention in Critically-Ill Patients | March 1, 2020 | August 23, 2023 | |
| NCT02715570 | Completed | Phase 1 | A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945 | October 23, 2017 | April 27, 2018 |
| NCT02180165 | Completed | Phase 3 | Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101) | July 29, 2014 | January 24, 2018 |
| NCT04935463 | Completed | Mucormycosis in COVID-19 | May 24, 2021 | March 1, 2022 | |
| NCT04818853 | Completed | COVID-19 Associated Pulmonary Aspergillosis (CAPA) and Other Invasive Fungal Infections (IFI) | March 9, 2021 | January 13, 2023 | |
| NCT04431804 | Completed | THYME AND CARVACROLL Nanoparticle Effect on Fungi | June 11, 2020 | September 30, 2020 | |
| NCT04232956 | Completed | Invasive Pulmonary Aspergillosis and Severe Influenza | July 27, 2018 | November 5, 2018 | |
| NCT05653193 | Not yet recruiting | Phase 2 | Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study | January 2024 | December 2025 |
| NCT06135597 | Recruiting | Immune Regulation in Chronic Aspergillus Infection After COVID-19 Infection | March 23, 2023 | December 31, 2025 | |
| NCT03828773 | Recruiting | N/A | PTX3-targeted Antifungal Prophylaxis | February 11, 2019 | November 30, 2025 |
| NCT04744454 | Recruiting | Post Marketing Surveillance (PMS) Study of Cresemba in Korea. | October 28, 2021 | January 30, 2026 | |
| NCT04868188 | Recruiting | Pharmacokinetics of Voriconazole in Adult ECMO Patients | August 24, 2021 | June 30, 2024 | |
| NCT01887457 | Suspended | Phase 2 | Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy | September 2014 | December 2016 |
| NCT03905447 | Terminated | Phase 2 | The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients. | September 17, 2019 | June 1, 2020 |
| NCT03870841 | Terminated | Phase 2 | The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis | April 3, 2019 | June 1, 2020 |
| NCT00047827 | Terminated | Phase 2 | Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis | December 2002 | February 2003 |
| NCT02646800 | Terminated | Phase 4 | Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp | March 21, 2014 | December 21, 2014 |
| NCT00620074 | Terminated | Phase 4 | Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene) | August 2008 | February 2009 |
| NCT01902030 | Unknown status | Evaluation of Performance of An Aspergillus PCR in Tissue and Pleural Effusion Samples of Immunocompromised Patients | January 2014 | December 2020 | |
| NCT01315925 | Unknown status | Pre-hospital Risk Factors for Invasive Fungal Infection | January 2010 | ||
| NCT04966234 | Unknown status | Phase 2/Phase 3 | A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection | April 22, 2021 | November 2023 |
| NCT00460330 | Unknown status | Evaluate Three Methods for Diagnosis of Invasive Fungal Infection in Chinese Patients After HSCT | April 2007 | December 2008 | |
| NCT01617759 | Unknown status | Aspergillus-specific PCR Assay in Cerebrospinal Fluid Samples for Detection of Central Nervous System Aspergillosis | September 2007 | December 2020 | |
| NCT01622595 | Withdrawn | UARK 2009-99 A Non-interventional Observational Study of Infectious Complications in Cancer Patients | November 2009 | December 2015 | |
| NCT01207128 | Withdrawn | Phase 2 | Trial of Combination Antifungal Therapy (Vori+Mica vs. Vori+Placebo) in Invasive Aspergillosis | February 2011 | January 2012 |
| NCT01188759 | Withdrawn | Phase 3 | Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects | May 2012 | August 2014 |
- Disase is a (Disease Ontology)
- DOID:2473
- Cross Reference ID (Disease Ontology)
- GARD:5856
- Cross Reference ID (Disease Ontology)
- ICD10CM:B44
- Cross Reference ID (Disease Ontology)
- ICD9CM:117.3
- Cross Reference ID (Disease Ontology)
- MESH:D001228
- Cross Reference ID (Disease Ontology)
- NCI:C2886
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:266218008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0004030
- Exact Synonym (Disease Ontology)
- Infection due to Aspergillus
- OrphaNumber from OrphaNet (Orphanet)
- 1163
- ICD10 preferred id (Insert disease from ICD10)
- D0000686
- ICD10 class code (Insert disease from ICD10)
- B44
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001228