Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IL10 MUTATION
IL10 MUTATION
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 )
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 ) - Associated Disease
- hepatitis B
- Source Database
- DisGeNET
- Description
- A recent genome-wide association study discovered that two polymorphisms, interferon (IFN) alpha receptor 2 (IFNAR-2) F8S and interleukin 10 receptor (IL10RB) K47E, were associated with susceptibility to hepatitis B virus (HBV) infection in Africa.
- Pubmed
- 19714778
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.04980214133244
- Year of publication
- 2009
Drugs