Immune System Diseases

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Disease name
Immune System Diseases
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03562975 Active, not recruiting Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus July 23, 2018 December 2023
NCT06107348 Active, not recruiting COVID-19 Post-Vaccination Observation July 1, 2021 December 24, 2023
NCT04309084 Active, not recruiting Phase 1 Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma May 12, 2020 April 30, 2023
NCT05445284 Active, not recruiting N/A Group Education Trial to Improve Transition for Parents of Adolescents With T1D October 10, 2023 March 2026
NCT05516758 Active, not recruiting Phase 2 A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis August 31, 2022 January 23, 2025
NCT04663204 Active, not recruiting Phase 2 A Study of the Safety and Activity of Sparsentan for the Treatment of Incident Patients With Immunoglobulin A Nephropathy December 10, 2020 March 31, 2025
NCT02663297 Active, not recruiting Phase 1 Administration of T Lymphocytes for Prevention of Relapse of Lymphomas July 15, 2016 January 2037
NCT06353035 Active, not recruiting N/A Biodiversity Interventions for Well-Being March 30, 2022 September 30, 2027
NCT01222039 Completed Phase 1/Phase 2 Multicenter Clinical Trial for the Evaluation of Mesenchymal Stem Cells From Adipose Tissue in Patients With Chronic Graft Versus Host Disease. June 2010 June 2014
NCT01328548 Completed Zoster Vaccine Response in the Frail Elderly May 2011 March 2015
NCT01425073 Completed N/A Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in Kenya February 2012 October 2013
NCT01441076 Completed Phase 1/Phase 2 Anakinra for Behcet s Disease September 2011 November 2014
NCT01472263 Completed Phase 3 Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases September 2009 September 2012
NCT01490177 Completed Phase 1 Single Center Food Allergy Oral Immunotherapy Study November 2011 April 2014
NCT01510626 Completed Phase 1 Omalizumab With Oral Food Immunotherapy With Food Allergies Open Label Safety Study in a Single Center November 2011 December 2015
NCT01727973 Completed Phase 1/Phase 2 Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathy October 2012 November 2013
NCT01764594 Completed Phase 1 Safety Study of CDP7657 in Patients With Systemic Lupus Erythematosus January 2013 August 2014
NCT01917760 Completed Pharmacokinetics Study of Gamma-aminobutyric Acid July 2013 December 2014
NCT02119143 Completed N/A Micronutrient Supplementation and Incidence of Common Cold April 2014 February 2017
NCT02162576 Completed N/A Asthma Data Innovation Demonstration Project June 2012 January 2014
NCT02294552 Completed Phase 2 Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT October 2014 November 2017
NCT02331446 Completed N/A The Effect of Different Volumes of Physical Exercise on the Immune System March 2014 September 2014
NCT02527122 Completed N/A Biological Stardadization of D. Pteronyssinus and D. Farinae Allergen Extracts July 21, 2016 August 2018
NCT02527187 Completed Phase 2 Determination of the Sensitivity and Specificity of Prick Test Betula Verrucosa September 2015 November 2016
NCT05210530 Completed Phase 1 An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D January 24, 2022 January 19, 2023
NCT04977739 Completed Research on the Application and Mechanism of New Biological Probes in Biomedicine August 3, 2021 July 25, 2022
NCT02630082 Completed N/A Feasibility of Measuring Immune Resp, Activation in Foreskin/Mucosa in HIV-, Uncircumcised High-HIV-risk MSM, Lima Peru April 2011 March 2013
NCT04837651 Completed Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab March 2, 2021 July 1, 2021
NCT02644759 Completed Phase 1/Phase 2 Transplantation of Autologous Stem Cells for the Treatment of Type 1 Diabetes Mellitus February 2014 May 2018
NCT04790201 Completed N/A Friendship Bench Adaptation to Improve Mental Health & HIV Care Engagement Outcomes Among PLWH and PWID in Vietnam February 28, 2022 July 31, 2023
NCT02824393 Completed Early Phase 1 Experimental Autologous Mesenchymal Stem Cell Therapy in Treatment of Chronic Autoimmune Urticaria March 3, 2017 July 15, 2018
NCT02916888 Completed A Study Comparing the Quality of Life of Patients in the Treatment of Eczema by Pediatric Generalists and Specialists September 2016 December 2017
NCT02966301 Completed Phase 2 Treatment of Chronic Graft Versus Host Disease With Arsenic Trioxide December 2016 June 2020
NCT03161288 Completed Phase 1 A Study of KY1005 in Healthy Volunteers May 29, 2017 March 30, 2018
NCT03199638 Completed N/A Exercise Snacks and Glutamine to Improve Glucose Control in Adolescents With Type 1 Diabetes April 1, 2016 June 30, 2017
NCT04653376 Completed Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases November 1, 2018 June 10, 2019
NCT03337165 Completed Phase 1 Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid Arthritis December 2016 August 2019
NCT04502940 Completed Is Lymphocyte Subtype Important for Acute Pancreatitis Severity? June 1, 2020 April 29, 2021
NCT03345004 Completed Phase 2 Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes December 20, 2017 April 27, 2021
NCT04449939 Completed Phase 1 A Study of Subcutaneous KY1005 in Healthy Volunteers July 7, 2020 November 30, 2020
NCT03503747 Completed Investigating Genetic Risk for Type 1 Diabetes April 25, 2018 August 31, 2021
NCT03563066 Completed Phase 2 Effect of Benralizumab in Atopic Dermatitis September 4, 2018 September 28, 2021
NCT04103099 Completed N/A Impact of HLNatural Immune Supplement on Colds October 16, 2019 August 15, 2020
NCT03997175 Completed N/A Effect of Modified Playground Environment on Health, Particularly Immune System April 15, 2018 July 30, 2018
NCT03627767 Completed Phase 3 Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects June 11, 2018 October 7, 2020
NCT03922087 Completed No-worry Baby Project November 20, 2018 September 30, 2023
NCT03688074 Completed Phase 2 Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE) November 2, 2018 November 16, 2020
NCT03720470 Completed Phase 3 Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy October 29, 2018 March 6, 2020
NCT00113464 Completed Developing Newborn Screening for Infants With Primary Immunodeficiency June 2, 2005 April 13, 2007
NCT00119548 Completed N/A Improving HIV Screening With Nurse-Based Rapid Testing/Streamlined Counseling March 2005 January 2007
NCT06286839 Completed N/A Study of Cannabidiol (CBD) in Healthy Volunteers May 12, 2022 December 14, 2022
NCT01056471 Completed Phase 1/Phase 2 Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis January 2010 June 2015
NCT01090102 Completed Phase 4 Mesalamine to Reduce T Cell Activation in HIV Infection June 2010 December 2012
NCT01093911 Completed Phase 1 Safety Study of CDP7657 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus (SLE) March 2010 December 2012
NCT01161056 Completed Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways May 2009 April 2015
NCT03594162 No longer available Compassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch
NCT05969821 Not yet recruiting Clonal Hematopoiesis of Immunological Significance September 2023 September 2043
NCT05910840 Not yet recruiting N/A Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care November 1, 2023 June 1, 2027
NCT05616117 Not yet recruiting Next-generation Effects of Vitamin D Supplementation in Pregnancy November 2022 November 2024
NCT06173544 Not yet recruiting N/A HIV Engagement and Adolescent Depression Support (HEADS-UP) July 2024 April 2025
NCT06353087 Not yet recruiting Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry) April 1, 2024 November 15, 2025
NCT06069583 Not yet recruiting N/A Implementation of Support in the Care of Adults Living With Type 1 Diabetes January 5, 2024 January 5, 2028
NCT04339777 Recruiting Phase 2 Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity September 22, 2020 November 30, 2027
NCT04656873 Recruiting Immuno-Oncology Database and Bioregistry May 20, 2021 April 2031
NCT03016377 Recruiting Phase 1/Phase 2 Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL March 22, 2012 April 22, 2041
NCT02690545 Recruiting Phase 1/Phase 2 Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL August 26, 2016 August 26, 2040
NCT06271252 Recruiting Phase 1 A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study April 3, 2024 April 12, 2028
NCT03672318 Recruiting Phase 1 Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma January 14, 2019 June 2028
NCT03663933 Recruiting Phase 2 Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation September 4, 2018 January 1, 2031
NCT03922724 Recruiting Phase 2 Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma April 18, 2019 June 30, 2029
NCT03602157 Recruiting Phase 1 Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL December 12, 2018 September 30, 2041
NCT00001406 Recruiting Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia April 21, 1997
NCT05509075 Recruiting Nutraceuticals and Functional Foods November 12, 2019 November 29, 2023
NCT05565248 Recruiting Phase 1/Phase 2 An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D January 20, 2023 August 2025
NCT05621317 Recruiting Phase 2 A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy February 9, 2023 July 2025
NCT05726461 Recruiting N/A Efficacy and Safety of Android Artificial Pancreas System in Adult Patients With Type 1 Diabetes Mellitus in China February 11, 2023 September 30, 2024
NCT05787574 Recruiting Phase 2 A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition March 15, 2023 March 2027
NCT05792176 Recruiting N/A Ukulele Playing to Improve Cognition in People With Multiple Sclerosis: A Feasibility Study March 27, 2023 August 1, 2025
NCT05928585 Recruiting Phase 1 A Study of Safety and Drug Levels of HIB210 in Healthy Volunteers July 6, 2023 April 2024
NCT06065592 Recruiting Phase 1 Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms February 1, 2019 December 2024
NCT06104111 Recruiting Phase 1 Epigenetic Memory of Vitamin D Supplementation October 1, 2023 March 30, 2025
NCT03696784 Recruiting Phase 1 Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma March 12, 2019 March 22, 2043
NCT06272370 Recruiting Phase 4 Individualizing Treatment for Asthma in Primary Care February 1, 2024 September 30, 2024
NCT06291415 Recruiting Phase 1 The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) April 2, 2024 November 2026
NCT00006150 Recruiting Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES) August 10, 2000
NCT02579967 Recruiting Phase 2 Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies November 19, 2015 December 21, 2028
NCT05414890 Recruiting Sensitivity and Specificity of TSA-CBA for Autoantibodies Against Neural Antigen Determination June 30, 2022 June 30, 2024
NCT04642066 Suspended N/A Cold Water Immersion and Atherosclerosis, Inflammation, Fat Accumulation and Lipid Profile Parameters October 25, 2018 June 30, 2026
NCT00260299 Terminated Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency February 2005 January 31, 2016
NCT02535052 Unknown status Investigating the Immune System in chrONIC Kidney Disease. July 2015
NCT02203682 Unknown status Phase 2 Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy July 2014 July 2022
NCT04319705 Unknown status Phase 4 Anti-viral Effects of Azithromycin in Patients With Asthma and COPD March 2, 2020 December 31, 2022
NCT01579110 Unknown status Phase 2 Efficacy and Safety of Levamisole Combined With Standard Prednisolone in Warm Antibody Autoimmune Hemolytic Anemia. April 2012 April 2016
NCT03344094 Unknown status Mechanism of Action of Ocrelizumab in Multiple Sclerosis October 12, 2017 December 31, 2019
NCT03578341 Unknown status Phase 3 Oral Colostrum and Its Effect on Immune System June 1, 2018 December 31, 2019
NCT01319643 Unknown status Phase 4 Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU) December 2009 November 2011
NCT03373019 Unknown status Phase 2 Chidamide Combined With R-GDP in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) December 21, 2017 March 1, 2021
NCT02640014 Unknown status N/A Oral Immunotherapy in Food Allergy in Finland December 2015 December 2021
NCT03311074 Withdrawn Phase 4 Retroviral Insertion Site Methodology Study June 25, 2020 July 9, 2020
NCT05431179 Withdrawn Phase 3 A Study of Zilovertamab and Ibrutinib in Patients With Relapsed or Refractory Mantle Cell Lymphoma March 2023 December 2026
MeSH unique ID (MeSH (Medical Subject Headings))
D007154