Nasal Polyps
Information
- Disease name
- Nasal Polyps
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02533206 | Active, not recruiting | N/A | Pilot Study of The EPIC Trial | August 2015 | December 2024 |
| NCT05865496 | Active, not recruiting | Phase 2 | A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps | June 30, 2023 | July 31, 2024 |
| NCT05274750 | Active, not recruiting | Phase 3 | Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps | April 22, 2022 | September 2, 2024 |
| NCT05281523 | Active, not recruiting | Phase 3 | Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2) | April 18, 2022 | August 6, 2024 |
| NCT03704415 | Active, not recruiting | N/A | Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative) | October 23, 2018 | December 31, 2024 |
| NCT00739921 | Completed | N/A | The Polymerase Chain Reaction (PCR) Analysis of Nasal Polyps for Fungal DNA | June 2006 | May 2015 |
| NCT00788463 | Completed | Phase 2 | A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polyps | November 23, 2006 | November 30, 2011 |
| NCT00788749 | Completed | Phase 4 | Medical Polypectomy and Predictors of Response | May 2004 | November 2008 |
| NCT00835445 | Completed | Biopsies and Polyps | July 2007 | September 2009 | |
| NCT00215787 | Completed | N/A | Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease | September 2005 | September 2008 |
| NCT01066104 | Completed | Phase 2 | Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis | December 2009 | July 2015 |
| NCT01198912 | Completed | Phase 2 | Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial | November 22, 2011 | February 6, 2017 |
| NCT01295866 | Completed | Evaluation Effects of Nasal Nitric Oxide Measurements Are Associated With Atopy Status in Chronic Nasal Inflammation | January 2010 | November 2010 | |
| NCT01362244 | Completed | Phase 2 | Mepolizumab in Nasal Polyposis | May 12, 2009 | December 5, 2014 |
| NCT01386125 | Completed | Phase 3 | A Study of the Effectiveness and Safety of Mometasone Furoate Nasal Spray (MFNS, SCH 032088) for the Treatment of Nasal Polyps (P05604) | June 2011 | February 2013 |
| NCT01623310 | Completed | Phase 3 | 12-Month OL Intranasal Fluticasone Propionate BID Using OptiNose Device | September 2013 | October 2015 |
| NCT01732536 | Completed | Phase 2/Phase 3 | Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps | January 2013 | May 2014 |
| NCT01819454 | Completed | N/A | The Diagnostics of Extraesophageal Reflux With the Restech System | August 2012 | December 2015 |
| NCT01827423 | Completed | N/A | Squamous Cell Carcinoma Antigen Analysis at the University Hospital Ostrava | January 2000 | January 2012 |
| NCT01920893 | Completed | Phase 2 | An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis | August 2013 | November 2014 |
| NCT02024659 | Completed | Phase 2/Phase 3 | Effects and Safety of Budesonide Inhalation Suspension Via Transnasal Nebulization in Nasal Polyps | September 2010 | January 2014 |
| NCT02110654 | Completed | Phase 4 | Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery | June 2014 | November 1, 2020 |
| NCT02194062 | Completed | N/A | Comparison of Nasal Steroids After FESS in CRSwNP | January 2015 | August 2015 |
| NCT02427503 | Completed | ATP Project (Asthma afTer Polypectomy) | July 2016 | December 16, 2019 | |
| NCT02476929 | Completed | N/A | Detection and Use of Nasal Nitrous Oxide and the Electronic Nose | January 2013 | December 2016 |
| NCT02484859 | Completed | Phase 4 | Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery | July 2015 | February 2016 |
| NCT03221192 | Completed | Qualitative Analysis of Subject Experience of Nasal Polyps | July 31, 2017 | February 28, 2018 | |
| NCT03694847 | Completed | Asthma With Nasal Polyposis | July 19, 2018 | September 15, 2018 | |
| NCT00440219 | Completed | Phase 3 | The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy. | November 2010 | June 2013 |
| NCT00465543 | Completed | Phase 2 | Mint Tea for the Treatment of Nasal Polyps | May 2007 | June 2008 |
| NCT00731185 | Completed | Phase 3 | Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218) | September 1, 2003 | September 1, 2005 |
| NCT03427502 | Completed | N/A | Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation | June 1, 2018 | February 28, 2020 |
| NCT03450083 | Completed | Phase 2 | Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis | July 1, 2017 | February 1, 2020 |
| NCT03478930 | Completed | Phase 3 | An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps | May 9, 2018 | March 16, 2020 |
| NCT02855931 | Completed | N/A | Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps | April 2016 | December 31, 2017 |
| NCT02874144 | Completed | Phase 2 | Anti-Inflammatory Agent in Sinusitis | June 20, 2016 | August 10, 2020 |
| NCT02879929 | Completed | Development and Validity of the DyNaChron Questionnaire for Chronic Nasal Dysfunction | October 2005 | December 2006 | |
| NCT00378378 | Completed | Phase 3 | Study of Nasonex® for the Treatment of Nasal Polyps in Pediatric Subjects Between Ages of 6 and Less Than 18 Years Old (P04292) | July 2006 | June 2008 |
| NCT03085797 | Completed | Phase 3 | Effect of Mepolizumab in Severe Bilateral Nasal Polyps | May 25, 2017 | December 11, 2019 |
| NCT05180357 | Completed | RANS. Study in Patients With Severe Eosinophilic Asthma and Nasal Polyps. | November 23, 2021 | October 28, 2022 | |
| NCT04996576 | Completed | N/A | Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESS | September 15, 2021 | May 1, 2022 |
| NCT03681093 | Completed | Phase 3 | Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma | March 26, 2019 | June 10, 2020 |
| NCT03228914 | Completed | Phase 4 | Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery | June 14, 2018 | August 29, 2018 |
| NCT03280537 | Completed | Phase 3 | A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polyps | November 21, 2017 | March 7, 2019 |
| NCT03280550 | Completed | Phase 3 | A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps | November 15, 2017 | March 11, 2019 |
| NCT03326063 | Completed | Phase 2 | Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban | April 26, 2018 | April 15, 2023 |
| NCT04805398 | Completed | Phase 2 | Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1) | April 6, 2021 | March 18, 2022 |
| NCT04804488 | Completed | Retrospective Study for Recurrent Nasal Polyposis | April 1, 2021 | April 30, 2022 | |
| NCT04607005 | Completed | Phase 3 | Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) | February 8, 2021 | April 12, 2023 |
| NCT06070311 | Not yet recruiting | N/A | Wound Healing After Endoscopic Sinus Surgery | October 2023 | October 2025 |
| NCT03607175 | Not yet recruiting | Phase 2/Phase 3 | Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposis | July 24, 2023 | December 30, 2025 |
| NCT06182982 | Not yet recruiting | N/A | Auriculotherapy for Intraoperative Blood Pressure Control | June 15, 2024 | July 30, 2024 |
| NCT06461949 | Recruiting | Phase 3 | Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray | June 23, 2024 | March 1, 2026 |
| NCT02975310 | Recruiting | N/A | In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps | April 11, 2017 | December 2025 |
| NCT04583501 | Recruiting | Early Phase 1 | Preclinical Studies of Omalizumab in Chronic Rhinosinusitis With Nasal Polyposis | December 15, 2020 | May 30, 2024 |
| NCT04852562 | Recruiting | N/A | The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps | December 6, 2020 | December 6, 2024 |
| NCT05009758 | Recruiting | N/A | Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps | September 1, 2021 | December 2024 |
| NCT05063981 | Recruiting | Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP. | November 25, 2021 | December 2024 | |
| NCT05094570 | Recruiting | Phase 4 | Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP | September 1, 2022 | December 31, 2024 |
| NCT05287841 | Recruiting | N/A | Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction? | April 30, 2021 | June 15, 2025 |
| NCT05575037 | Recruiting | Phase 2 | Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease | August 1, 2023 | April 30, 2026 |
| NCT05672030 | Recruiting | Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP | October 1, 2022 | December 1, 2023 | |
| NCT05828199 | Recruiting | Phase 1 | The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose Ketamine | December 1, 2022 | December 20, 2023 |
| NCT05869071 | Recruiting | Assessment of Oral and Nasal Breathing With Sensors Analyzing Algorithm | May 23, 2023 | June 30, 2024 | |
| NCT06036927 | Recruiting | Phase 2 | A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps | December 8, 2023 | September 2025 |
| NCT06362122 | Recruiting | N/A | Anatomo-clinico-biological Profiles in Severe Nasal Polyps | June 3, 2024 | October 3, 2026 |
| NCT04261582 | Suspended | Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD) | November 6, 2018 | April 2022 | |
| NCT03102190 | Terminated | Phase 1 | Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polyps | June 5, 2017 | March 26, 2018 |
| NCT02454608 | Terminated | N/A | Trial of Verapamil in Chronic Rhinosinusitis | May 2015 | May 2017 |
| NCT03362515 | Terminated | Phase 2 | Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide | December 1, 2017 | April 14, 2022 |
| NCT01616160 | Terminated | Phase 4 | An Open-label Study to Identify Molecular Markers of Steroid Resistance | July 2013 | January 9, 2018 |
| NCT01222871 | Terminated | Phase 1/Phase 2 | Treatment of Early Nasal Polyposis With Topical Triamcinolone | July 2010 | August 2012 |
| NCT04104594 | Terminated | N/A | Olfaction and Inflammation in Chronic Rhinosinusitis With Nasal Polyps | February 5, 2020 | July 29, 2021 |
| NCT03963648 | Unknown status | N/A | NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP | September 13, 2019 | June 1, 2022 |
| NCT03965767 | Unknown status | Phase 3 | Does The Combined Use Of Local And Intravenous Tranexamic Acid Offer Better Surgical Field Quality During Functional Endoscopic Sinus Surgery? A Placebo-Controlled Clinical Trial | April 25, 2019 | September 1, 2019 |
| NCT04105361 | Unknown status | N/A | Impact of Posterior Nasal Neurectomy With Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis:A Comparative Study | January 2020 | October 2021 |
| NCT04185012 | Unknown status | Phase 3 | NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to Benralizumab | February 24, 2020 | July 30, 2022 |
| NCT03943121 | Unknown status | N/A | The Effects of Steroid-eluting Stent Implant for the Treatment of Eosinophilic Chronic Rhinosinusitis With Nasal Polyps | October 8, 2018 | October 1, 2021 |
| NCT04888910 | Unknown status | Novel Inflammatory Markers in Different Phenotypes of Severe Asthma | March 1, 2021 | February 28, 2023 | |
| NCT03151954 | Unknown status | N/A | The Activation of Hippo Pathway in Nasal Polyps | April 20, 2017 | July 31, 2020 |
| NCT01564849 | Unknown status | The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic Rhinosinusitis | April 2012 | February 2017 | |
| NCT05157412 | Unknown status | Phase 3 | Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps | March 1, 2022 | March 1, 2024 |
| NCT03472144 | Unknown status | Phase 3 | Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis | July 7, 2017 | December 7, 2019 |
| NCT05405478 | Unknown status | Phase 4 | Omalizumab Efficacy in Patients With Refractory Nasal Polyps | June 1, 2022 | January 23, 2023 |
| NCT03374124 | Unknown status | The Surgical Prognosis Based Diagnostic Strategy for Eosinophilic Chronic Rhinosinusitis | January 2016 | June 2018 | |
| NCT00841802 | Withdrawn | Phase 4 | Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study | July 2008 | June 30, 2019 |
| NCT03369574 | Withdrawn | Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With Reslizumab | November 14, 2017 | October 19, 2018 | |
| NCT02071667 | Withdrawn | Association of Periostin Levels and Chronic Sinusitis | September 2014 | October 2016 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D009298