retinal vein occlusion

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Information
Disease name
retinal vein occlusion
Disease ID
DOID:1727
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05003258 Active, not recruiting N/A Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection October 7, 2021 October 30, 2024
NCT05532735 Active, not recruiting Phase 2 Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion August 24, 2022 July 30, 2024
NCT00088283 Completed Phase 2 Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) May 2004
NCT00101764 Completed Phase 1 Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders January 5, 2005 May 20, 2008
NCT00105027 Completed Phase 3 The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study October 2004 February 2009
NCT00106132 Completed Phase 3 Steroid Injections vs. Standard Treatment for Macular Edema Due to Retinal Blood Vessel Blockage March 2005 November 2005
NCT00168298 Completed Phase 3 A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion November 1, 2004 September 5, 2008
NCT00168324 Completed Phase 3 A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion October 1, 2004 October 1, 2008
NCT00403039 Completed Phase 1 Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edema November 2006 December 2011
NCT00407355 Completed Phase 1/Phase 2 Ranibizumab (Lucentis) for Macular Edema Secondary to Vein Occlusions January 2006 February 2013
NCT00485836 Completed Phase 3 A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion (CRUISE) July 2007 December 2009
NCT00486018 Completed Phase 3 A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch Retinal Vein Occlusion (BRAVO) July 2007 November 2009
NCT00493064 Completed Phase 2/Phase 3 To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions October 2006 October 2016
NCT01318941 Completed Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting March 2011 April 2016
NCT00071227 Completed Phase 1 Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorders October 15, 2003 August 15, 2007
NCT01377597 Completed Phase 3 Efficacy and Safety of Ranibizumab in Japanese Patients With Retinal Vein Occlusion June 2011 April 2012
NCT01411696 Completed Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO) July 2011 March 2012
NCT01427751 Completed Phase 4 Safety and Efficacy Study of Ozurdex® Compared to Lucentis® in Patients With Branch Retinal Vein Occlusion October 11, 2011 November 4, 2014
NCT01428388 Completed N/A Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion September 2011 December 2015
NCT01442064 Completed N/A An Extension Study to Evaluate Safety and Tolerability of Ranibizumab in Macular Edema Secondary to Retinal Vein Occlusion (Cohort 2) July 2008 July 2010
NCT01449682 Completed Phase 3 Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections. October 2011 February 2013
NCT01468831 Completed Phase 1/Phase 2 Minocycline to Treat Branch Retinal Vein Occlusion March 28, 2012 March 18, 2021
NCT01468844 Completed Phase 1/Phase 2 Minocycline to Treat Central Retinal Vein Occlusion December 21, 2011 May 13, 2015
NCT01539577 Completed A Long-Term Safety Study of OZURDEX® in Clinical Practice March 2012 March 2016
NCT01566526 Completed Retrospective Data Collection Study in Patients Receiving Two or More OZURDEX® Injections for Macular Oedema Secondary to Retinal Vein Occlusion March 2012 June 2012
NCT01568021 Completed Post Market Surveillance of OZURDEX® for Branch Retinal Vein Occlusion (BRVO) and Central Retinal Vein Occlusion (CRVO) October 2011 November 2013
NCT01571557 Completed A Safety and Efficacy Study to Assess OZURDEX® in Patients With Macular Oedema Secondary to Retinal Vein Occlusion (RVO) April 30, 2012 June 30, 2014
NCT01573572 Completed Phase 4 Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium April 22, 2010 November 14, 2019
NCT01580020 Completed Phase 4 Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO May 2012 October 2014
NCT01618266 Completed Study of Ozurdex® Treatment Practice in Patients With Macular Oedema Due to Retinal Vein Occlusion November 2011 October 2014
NCT01662518 Completed Phase 1/Phase 2 DDS-25 Gauge in Patients With Macular Edema Secondary to Retinal Vein Occlusion (RVO) July 2011 June 2016
NCT01692938 Completed Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO October 2012 November 2012
NCT01790685 Completed Phase 2/Phase 3 Ozurdex for Retinal Vein Occlusion Study (ORVO Study) February 2013 December 2014
NCT01903720 Completed Phase 4 A Safety and Efficacy Study of OZURDEX® in Macular Edema Associated With Branch Retinal Vein Occlusion July 16, 2013 March 30, 2015
NCT01918371 Completed A Retrospective Study of Anti-Vascular Endothelial Growth Factor (VEGF) Injections for Retinal Vein Occlusion or Diabetic Macular Edema August 2, 2013 September 4, 2014
NCT01976650 Completed Safety and Efficacy of Dexamethasone (OZURDEX®) Intravitreal Implant in Korea March 2011 March 2015
NCT02040220 Completed Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Eylea for Central Retinal Vein Occlusion (CRVO) January 24, 2014 November 9, 2018
NCT02118831 Completed Phase 1/Phase 2 Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF March 2012 April 2014
NCT02126423 Completed Resistance to Antibiotics in Patients Receiving Eye Injections May 2014 September 2014
NCT02140411 Completed Phase 4 Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema. April 25, 2015 December 21, 2016
NCT02181530 Completed Retrospective Data Collection Study in Patients With Macular Oedema Receiving OZURDEX® July 2014 October 2014
NCT02245516 Completed N/A Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic Macular Edema July 2014 December 2014
NCT02303184 Completed Phase 2 Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO January 2015 March 2016
NCT02387788 Completed Phase 2 Open Label Study to Assess the Efficacy and Safety of AKB-9778 in Subjects With Macular Edema Due to RVO January 2015 April 2017
NCT02503540 Completed Phase 4 Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO August 18, 2015 February 6, 2018
NCT02521116 Completed N/A Comparison of Retinal Oxygenation and Retinal Vessel Diameters in Healthy Subjects and Patients With Diabetic Retinopathy or Retinal Vein Occlusion Between DVA and Oxymap February 2016 February 28, 2018
NCT02523339 Completed Study of Retinal Oxygenation in Central Retinal Vein Occlusion October 2014 November 3, 2020
NCT02571972 Completed Phase 2 Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME. February 1, 2015 December 20, 2015
NCT02614937 Completed Phase 1/Phase 2 Study of Squalamine Lactate for the Treatment of Macular Edema Related to Retinal Vein Occlusion April 2013 December 2014
NCT02645747 Completed Retrospective Data Analysis of Patients Treated for Macular Edema Due to Central Retinal Vein Occlusion January 21, 2016 December 23, 2017
NCT02880644 Completed Ultra-wide Fluorescein Angiography in Patients With Central Retinal Vein Occlusion Treated by Afilbercept January 26, 2017 November 30, 2022
NCT02898480 Completed N/A Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning September 2016 May 2017
NCT02956330 Completed Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201 November 2016 April 12, 2017
NCT03038048 Completed N/A 30g vs 33g Needle for Intravitreal Injections January 27, 2017 April 27, 2017
NCT03093701 Completed Phase 2 TLC399 (ProDex) in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO) April 1, 2017 February 4, 2019
NCT03753893 Completed Ocular Manifestations in Rheumatic Diseases May 1, 2013 November 1, 2021
NCT03908307 Completed Phase 4 Evaluation of OZURDEX® in Patients With Macular Edema Secondary to Retinal Vein Occlusion in China July 25, 2019 September 26, 2021
NCT04395859 Completed Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents May 27, 2020 February 15, 2022
NCT04592419 Completed Phase 3 A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO) September 25, 2020 January 19, 2023
NCT04635800 Completed Phase 1 A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients December 10, 2020 May 24, 2022
NCT04723160 Completed Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph August 10, 2020 May 30, 2021
NCT05038072 Completed N/A The Use of Suprachoroidal Triamcinolone Acetonide to Treat Macular Edema in Retinal Vein Occlusion July 25, 2019 February 28, 2021
NCT05345808 Completed N/A Efficacy of Formulated Posterior Sub Tenon Triamcinolone in Macular Edema Secondary to Non-Ischemic Retinal Vein Occlusions March 1, 2021 March 30, 2022
NCT06176963 Completed Phase 2 A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVO November 21, 2023 December 12, 2023
NCT06213896 Completed Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus Images March 1, 2023 April 18, 2024
NCT06416241 Completed Phase 4 Intravitreal Aflibercept for Macular Edema Due to Central Retinal Vein Occlusion January 1, 2017 March 31, 2024
NCT00636493 Completed Early Phase 1 Fluocinolone Acetonide Implant for Retinal Vein Occlusion (RVO) October 2002 May 2009
NCT00804102 Completed N/A Transcorneal Electrical Stimulation Therapy for Retinal Disease January 2008 April 2011
NCT00805064 Completed Phase 3 Combined Triple Procedure in Retinal Vein Occlusion (RVO) January 2006 November 2008
NCT00831350 Completed Phase 2 Posterior Vitreous Detachment (PVD) Assessment During Dual Retinal Vein Occlusion (RVO) Lucentis Evaluations April 2009 December 2012
NCT00942864 Completed Phase 3 Effect of Intravitreal Ranibizumab Injection With Retinal Vein Occlusion (RVO) December 2008 December 2009
NCT00970957 Completed Phase 3 Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion September 2009 February 2013
NCT01003106 Completed Phase 1/Phase 2 Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusions November 2009 April 2015
NCT01012973 Completed Phase 3 Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO) October 2009 February 2012
NCT01027481 Completed Phase 4 Ranibizumab in Patients With Branch Retinal Vein Occlusion December 2007 December 2009
NCT01027650 Completed Phase 1/Phase 2 Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO) March 2010 February 2013
NCT01198327 Completed Phase 3 Extended Follow-up of Patients With Macular Edema Due to Retinal Vein Occlusion August 2010 December 2012
NCT00000131 Completed Phase 3 Central Vein Occlusion Study (CVOS) August 1988 February 1994
NCT05675540 Not yet recruiting Artificial Intelligence Diagnostic Aid June 1, 2023 March 30, 2024
NCT04008121 Not yet recruiting Early Phase 1 Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium April 2024 July 2024
NCT06343961 Not yet recruiting N/A Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy April 18, 2024 December 2025
NCT05099094 Recruiting Early Phase 1 VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases November 25, 2021 September 2023
NCT05130385 Recruiting High Resolution Optical Coherence Tomography November 30, 2021 November 30, 2023
NCT05133791 Recruiting Phase 1 NIR Fluorescence Molecular Imaging of ANXV-800CW in RVO Patients September 23, 2021 May 1, 2024
NCT01496625 Recruiting National Eye Institute Biorepository for Retinal Diseases June 18, 2012
NCT05532475 Recruiting Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion March 12, 2022 October 2022
NCT04505618 Recruiting N/A Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease October 1, 2019 September 1, 2025
NCT05496530 Recruiting N/A Custom Needle Preparation for Suprachoroidal Steroid Injection (One Year Results) July 10, 2022 August 15, 2023
NCT06439576 Recruiting Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study) May 9, 2024 November 30, 2027
NCT03680794 Recruiting N/A Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies June 27, 2018 February 1, 2025
NCT04075695 Recruiting Ultra-wide-field Fluorescein Angiography in Patients With Retinal Vein Occlusion September 18, 2019 August 12, 2025
NCT06332690 Recruiting OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO October 17, 2023 December 2025
NCT04140448 Recruiting Ultra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein Occlusion October 9, 2023 December 15, 2025
NCT06262737 Recruiting Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction Protocol September 30, 2023 October 1, 2025
NCT04707625 Terminated Phase 4 Vascular Endothelial Growth Factor (VEGF) Levels in Retinal Vein Occlusion (RVO) During Anti-VEGF Treatment October 6, 2021 December 18, 2023
NCT00732927 Terminated Phase 3 Parnaparin vs Aspirin in the Treatment of Retinal Vein Occlusion July 2002 September 2007
NCT00770770 Terminated Phase 2 Fluocinolone Acetonide Intravitreal Inserts for Vein Occlusion in Retina May 2009
NCT04563299 Terminated Phase 4 Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections December 9, 2020 February 14, 2023
NCT02510885 Terminated N/A SD-OCT Angiography July 2015 March 11, 2019
NCT01225146 Terminated Phase 1 Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2) October 2010 August 2012
NCT00379223 Terminated N/A Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized Trial October 2006 September 2008
NCT02980874 Terminated Phase 3 Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO January 31, 2017 December 10, 2018
NCT03203447 Terminated Phase 3 Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO March 5, 2018 December 18, 2018
NCT03790852 Terminated Phase 1 Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO December 26, 2018 June 9, 2022
NCT01717937 Terminated Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging February 2013 June 2013
NCT01875770 Terminated Continuing Assessment of Patients Treated With ranibizUmab for REtinal Vein Occlusion (CAPTURE) January 2013 March 3, 2021
NCT02088151 Terminated N/A Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the Retina June 2010 February 1, 2022
NCT04062370 Unknown status Phase 4 Ranibizumab Treatment for Macular Edema Secondary to Retinal Vein Occlusion October 1, 2019 August 31, 2022
NCT03489915 Unknown status Correlation Between the Visual Acuity & the OCT Pattern of Macular Edema Secondary to RVO May 1, 2018 May 2020
NCT03525132 Unknown status N/A Study of the Retinal Vascularization by Laser Doppler Velocimetry Coupled With an Adaptive Optics Camera ( AO-LDV) September 18, 2015 September 18, 2020
NCT01123564 Unknown status Phase 2 Efficacy and Safety of Lucentis for Clinically Significant Macular Edema Secondary to Central Retinal Vein Occlusion August 2009 September 2011
NCT01581151 Unknown status N/A Ozurdex With Rescue Lucentis for Treating Macular Edema Secondary to Retinal Vein Occlusion September 2011 June 2015
NCT00517257 Unknown status Phase 3 Atorvastatin for the Treatment of Retinal Vein Occlusion August 2007 September 2009
NCT01635803 Unknown status Phase 2/Phase 3 Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Retinal Vein Occlusions (BRVO) June 2012
NCT03762226 Unknown status Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study September 1, 2018 December 31, 2021
NCT04142164 Unknown status N/A Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug Injections October 24, 2019 January 1, 2024
NCT02257333 Unknown status Retinal Thrombosis and Atherosclerosis September 1, 2015 September 2020
NCT01011374 Unknown status Phase 1 Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusion November 2009 November 2013
NCT01809236 Unknown status Phase 2 Efficacy and Safety of Conbercept in Macular Edema Secondary to Retinal Vein Occlusion May 2012 March 2014
NCT01857544 Unknown status Phase 4 Study of Intravitreal Aflibercept Injection for Persistent CRVO-associated Macular Edema Despite Prior Anti-VEGF Therapy June 2013 March 2016
NCT04847869 Unknown status N/A Near-Infrared Light Photobiomodulation Treatment for Retinal Vein Occlusion Macular Oedema January 1, 2021 July 31, 2022
NCT03391219 Unknown status Phase 2/Phase 3 Combined Intravitreal Injection of Bevacizumab and Fasudil Versus Bevacizumab Alone for Macular Edema Secondary to Retinal Vein Occlusion in Previously Treated Patients January 2018 October 2018
NCT03918590 Unknown status Phase 4 Post Intravitreal Injection Topical NSAID vs. Patching December 3, 2018 June 3, 2019
NCT02486484 Unknown status Phase 2 Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection March 2015 December 2019
NCT03056079 Unknown status Phase 4 Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept February 28, 2017 February 28, 2024
NCT03056092 Unknown status Phase 4 Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab February 28, 2017 February 28, 2024
NCT05222633 Unknown status Anti-VEGF in Real-world January 1, 2022 May 1, 2023
NCT00211354 Withdrawn Phase 2 Treatment of Retinal Vein Occlusion (RVO) With Open-Label Anecortave Acetate (15mg.) March 2002 April 2007
NCT04011358 Withdrawn N/A Retinal Vein Occlusion and Obstructive Sleep Apnea: A Case Control Study September 2021 September 2022
Disase is a (Disease Ontology)
DOID:1729
Cross Reference ID (Disease Ontology)
MESH:D012170
Cross Reference ID (Disease Ontology)
NCI:C34981
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:46085004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0035328
Exact Synonym (Disease Ontology)
Occlusion, of retinal vein
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0012636
MedGen concept unique identifier (MedGen Concept name)
C0035328
MedGen unique identifier (MedGen Concept name)
19763
MeSH unique ID (MeSH (Medical Subject Headings))
D012170