Recurrent pregnancy loss

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Information
Disease name
Recurrent pregnancy loss
Disease ID
Description
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
NOP14 4 2,937,936 2,963,406 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04744025 Active, not recruiting N/A Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates January 13, 2021 December 31, 2022
NCT04621773 Active, not recruiting Live Birth Rate in Patients With Unexplained Recurrent Pregnancy Loss September 1, 2020 September 1, 2025
NCT01542411 Completed Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment April 2008
NCT00721591 Completed Pharmacokinetics of Low Molecular Weight and Unfractionated Heparin in Pregnancy March 2005 July 2014
NCT04455256 Completed Evaluation of Endoplasmic Reticulum Stress in Patients With Recurrent Pregnancy Loss March 20, 2020 July 7, 2020
NCT05802784 Completed N/A Hysteroscopic Septoplasty by Different Modalities June 16, 2020 March 21, 2023
NCT04017754 Completed Low Plasma Mannose Binding Lectin (p-MBL) Level is a Risk Factor for Recurrent Pregnancy Loss (RPL) January 1, 2016 March 29, 2021
NCT05073978 Completed B-vitamin Levels and Adverse Pregnancy Outcomes December 1, 2020 December 31, 2022
NCT02386384 Completed TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure March 2015 July 2017
NCT02572154 Completed N/A Sperm DNA Fragmentation in Recurrent Pregnancy Loss September 2012 July 2015
NCT04718233 Completed Phase 2 Effect of Sildenafil Citrate on Mid Luteal Phase Uterine Artery Blood Flow in Patients With Recurrent Pregnancy Loss September 5, 2018 July 1, 2019
NCT03401918 Completed Phase 2 Assessing the Endometrial Environment in Recurrent Pregnancy Loss and Unexplained Infertility August 1, 2017 July 1, 2021
NCT05205044 Completed Evaluation of Apelin-13 and Apelin-36 in Women With Recurrent Pregnancy Loss January 23, 2022 January 30, 2023
NCT03178682 Completed Ultrasound Predictors of Early Pregnancy Failure in Patients With Recurrent Pregnancy Loss January 1, 2017 October 1, 2017
NCT03174951 Completed Phase 2 Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Pregnancy Loss September 20, 2016 June 20, 2017
NCT05342948 Completed Association of HY-restricting HLA Class II Alleles, Sex of Firstborn Child, and Pregnancy Outcome in RPL Patients January 1, 2016 October 1, 2022
NCT05520112 Not yet recruiting Phase 1/Phase 2 Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells November 1, 2022 December 31, 2023
NCT05612620 Not yet recruiting Elucidating the Microbiome in Patients With Recurrent Pregnancy Loss November 14, 2022 September 2023
NCT05167812 Not yet recruiting On Pregnancy After Losses - OPAL Study February 1, 2022 February 1, 2028
NCT04701034 Recruiting Phase 2 Intravenous Immunoglobulin and Prednisolone for RPL After ART. February 6, 2021 August 1, 2023
NCT05186207 Recruiting Establishment of Special Disease Cohort for RPLand Study of Impact Mechanism of Early Embryo Development January 12, 2022 December 31, 2024
NCT06182878 Recruiting N/A Tender Loving Care for Recurrent Pregnancy Loss January 1, 2024 December 1, 2025
NCT05656846 Recruiting N/A Biweekly Follow-Up and At-Home Ultrasound Reduce Anxiety in Women With Recurrent Pregnancy Loss July 15, 2022 April 1, 2025
NCT05725512 Recruiting Phase 4 Prednisolone Administration in Patients With Unexplained REcurrent MIscarriages January 29, 2024 July 29, 2027
NCT05989178 Recruiting Prospective Recurrent Pregnancy Loss Registry July 12, 2022 December 31, 2032
NCT06007560 Recruiting N/A Aerobe Cycling Training in Women With Unexplained Recurrent Pregnancy Loss March 21, 2022 August 2024
NCT05444283 Recruiting Genomic Predictors of Recurrent Pregnancy Loss September 1, 2021 September 2026
NCT04397042 Suspended SCUBE-1 and Carotid Intima Media Thickness in Recurrent Pregnancy Loss May 22, 2020 June 23, 2022
NCT01546350 Suspended Phase 2 Preimplantation Genetic Diagnosis Using Blastocyst Biopsy and Array CGH March 2012 June 2014
NCT00564174 Terminated N/A Low Molecular Weight Heparin and Aspirin in the Treatment of Recurrent Pregnancy Loss: A RCT March 2000 September 2005
NCT05186779 Terminated Maternal and Newborn Safety Profile of Progestogens in EARLY Pregnancy December 15, 2021 July 14, 2023
NCT01325805 Terminated N/A Efficacy of a Structured Weight Loss Program in Overweight Women With a History of Recurrent Pregnancy Loss December 2010 December 2013
NCT03690830 Unknown status N/A Use of Metabolomics for the Identification of Endometrial Biomarkers for IRPL and RIF After in Vitro Fertilization January 1, 2019 January 1, 2021
NCT03671174 Unknown status N/A Immunosuppressant Regimens for Living Fetuses Study August 2, 2019 February 2023
NCT01635426 Unknown status Phase 2/Phase 3 Aspirin Versus Clopidogrel Effect on Uterine Blood Flow in Women With Unexplained Recurrent Miscarriages March 2012 March 2018
NCT03305263 Unknown status Phase 3 Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss January 25, 2018 January 2023
NCT05237843 Unknown status Phase 1 Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss March 1, 2022 January 2023
NCT05341856 Unknown status Early Phase 1 Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL May 1, 2022 September 2022
NCT03214185 Unknown status N/A Effects of PGS2.0 in Patients With Unexplained RPL February 6, 2018 September 30, 2021
NCT03106935 Unknown status Early Phase 1 Recurrent Pregnancy Loss and Thyroid Disease July 2015 June 2018
NCT02990403 Unknown status Phase 4 The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss October 2014 December 22, 2018
NCT02990390 Unknown status The Epidemiology of Recurrent Spontaneous Abortion Associated With Thrombophilla November 2016 October 2019
NCT05169541 Unknown status Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction February 2, 2022 November 30, 2022
NCT02156063 Unknown status Phase 2 A Multi-center, Placebo-controlled Study to Evaluate NT100 in Pregnant Women With a History of Unexplained Recurrent Pregnancy Loss (RPL) June 2014 June 2016
NCT02144064 Unknown status Phase 3 Pregnancy Outcomes in Women With Unexplained Recurrent Pregnancy Loss Treated With Low Dose Aspirin and Unfractionated Heparin June 23, 2019 December 2022
NCT01946945 Unknown status Phase 2 Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis September 2013
NCT03905395 Unknown status N/A Meditation and Mindfulness for Recurrent Pregnancy Loss February 2, 2019 June 30, 2020
NCT02379650 Withdrawn Phase 2 Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss July 2016 July 2021