Constipation

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Disease name
Constipation
Disease ID
Description
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NCT ID Status Phase Summary Start date Completion date
NCT04961840 Active, not recruiting A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy January 1, 2022 December 1, 2025
NCT03499808 Active, not recruiting Phase 2 S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis June 6, 2018 July 31, 2025
NCT05490654 Active, not recruiting N/A Abdominal Massage for People With Learning Disabilities and Constipation June 14, 2022 December 2023
NCT04182633 Active, not recruiting Phase 2 MTT for Children With ASD Who Have Gastrointestinal Disorders November 15, 2019 December 30, 2024
NCT04027972 Active, not recruiting Early Phase 1 Pharmacokinetics of Neostigmine and Glycopyrrolate March 9, 2020 September 28, 2024
NCT02571881 Active, not recruiting Phase 4 Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section October 2012 December 2023
NCT06274242 Active, not recruiting N/A Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults March 10, 2023 April 19, 2024
NCT02442115 Active, not recruiting Impact of Improving GI Symptoms on Autism Symptoms and Oxidative Stress September 2009 December 2023
NCT06351995 Active, not recruiting Phase 3 Neostigmine and Glycopyrrolate by Iontophoresis November 6, 2020 January 1, 2025
NCT06014008 Active, not recruiting N/A Effect of L. Paracasei Strain Shirota on Constipation in Healthy US Adults September 18, 2023 July 2024
NCT00164125 Completed Phase 4 An Open Label Study of Chronic Polyethyleneglycol3350 Use in Constipated Patients July 2003
NCT00171522 Completed Phase 4 Preference of Tegaserod vs. PEG 3350 in Patients With Constipation May 2005 September 2005
NCT00230360 Completed Diagnosis of Functional Defecation Disorders in Childhood June 2005 April 2006
NCT00241722 Completed Phase 3 Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain August 1, 2005 February 1, 2007
NCT00256932 Completed Phase 3 Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain August 2005 May 2006
NCT00259922 Completed Phase 3 Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain August 2005
NCT00276354 Completed Phase 4 Study of Long-term Use of Forlax® in Elderly Patients With Chronic Constipation December 1999 November 20, 2001
NCT00276406 Completed Phase 1/Phase 2 Use of Pyridostigmine for Constipation in Diabetics May 2006 October 2010
NCT00286520 Completed Phase 4 Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury December 2003 August 2005
NCT00299975 Completed Phase 2 A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation October 2006 October 2007
NCT00306748 Completed Phase 2 Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation March 2006 August 2006
NCT00311350 Completed Phase 1 Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects March 2006 August 2006
NCT00319670 Completed Phase 4 A Pilot Study of a New MiraLax® Dose Formulation For Use in Constipated Children March 2006
NCT00345397 Completed N/A A Colonic Tube to Improve Bowel Function in Spinal Cord Injury May 1, 2006 December 31, 2018
NCT00366431 Completed Phase 2 Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain August 2006 March 2007
NCT00368823 Completed Phase 3 A Trial of Point of Care Information in Ambulatory Pediatrics November 1999 December 2003
NCT00398021 Completed Predictors of Constipation in Healthy Children June 2006 March 2010
NCT00399542 Completed Phase 3 Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation May 2005 July 2006
NCT00444158 Completed Phase 1 Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects March 2007 July 2007
NCT00452335 Completed Phase 4 Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation January 2007 October 2008
NCT00483886 Completed Phase 3 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation April 1998 May 1999
NCT00485940 Completed Phase 3 Efficacy and Safety Study of Prucalopride for the Treatment of Patients With Chronic Constipation March 1998 May 1999
NCT00487422 Completed Phase 3 Efficacy and Safety Study of Prucalopride for the Treatment of Elderly Patients With Chronic Constipation October 1998 September 1999
NCT00488137 Completed Phase 3 Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation March 1998 July 1999
NCT00488215 Completed Phase 1 A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride January 2000 March 2000
NCT00502957 Completed N/A Biofeedback Treatment for Functional Constipation March 2005 November 2007
NCT00508482 Completed Phase 2 A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional Constipation April 2008 November 2011
NCT00513656 Completed Phase 2 A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain September 2007 June 2010
NCT00521872 Completed Phase 4 Stapled Trans Anal Rectal Resection (STARR) for Outlet Obstruction: Functional and Morphological Outcome April 2004 October 2007
NCT00526097 Completed Phase 3 Dulcolax vs Placebo in Functional Constipation September 2007
NCT00529087 Completed Phase 3 Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain August 2007 December 2008
NCT00547586 Completed Phase 2 Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain October 2007 February 2008
NCT00571896 Completed Phase 2/Phase 3 The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery January 2008 June 2009
NCT00575614 Completed Phase 2 Prucalopride in Patients With Chronic Idiopathic Constipation April 1997 March 1999
NCT00576810 Completed Phase 3 Sodium Picosulphate vs. Placebo in Functional Constipation October 2007
NCT00577018 Completed Phase 3 Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation August 1998 September 1999
NCT00583154 Completed Phase 2 A Pilot Efficacy Evaluation of BLI-801 as a Laxative in Constipated Adults October 2007 April 2008
NCT00583609 Completed Phase 4 A Pilot Study of a New PEG3350 Dose Formulation For Use in Constipated Children September 2007 July 2008
NCT00596596 Completed Phase 2 Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation September 1996 June 1997
NCT00598338 Completed Phase 3 Efficacy and Safety Study of Prucalopride for the Re-Treatment of Chronic Constipation April 1999 February 2000
NCT00603681 Completed Phase 4 Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation January 2008 July 2008
NCT00603707 Completed Assessment of Whole Gut Transit Time Using the SmartPill Capsule October 2006 June 2008
NCT00605644 Completed Phase 2 Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain January 2008 May 2008
NCT00611299 Completed Phase 1 Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults April 2003 November 2003
NCT00617513 Completed Phase 2 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation March 1995 March 1996
NCT00627692 Completed Phase 2 Evaluation of the Safety and Tolerability of Prucalopride in Constipated Elderly Subjects Living in a Nursing Facility February 1999 May 2000
NCT00631813 Completed Phase 2 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation November 1995 April 1997
NCT00662363 Completed N/A Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation April 2008 October 2011
NCT00677508 Completed Development of an Instrument to Measure Quality of Life in Children With Chronic Constipation and Soiling September 2005 August 2011
NCT00706004 Completed N/A Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic Fibrosis July 2008 December 2009
NCT00712543 Completed Phase 4 A Preference Study Comparing Kristalose® and Liquid Lactulose June 2009 September 2009
NCT00728975 Completed The Bowel Research Collaborative Data Tracking System Implementation Study June 2008 February 2010
NCT00735605 Completed N/A Comparative Study Between Surgical and Non Surgical Treatment of Anismus in Patients September 2006 January 2010
NCT00741936 Completed Phase 2 An Effectiveness and Safety Study of Chinese Herbal Medicine for Functional Constipation July 2008 December 2009
NCT00763399 Completed Phase 4 Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation October 2008 May 2010
NCT00765557 Completed Early Phase 1 Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome December 10, 2007 July 22, 2014
NCT00770432 Completed Phase 4 Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216) November 2007 January 2008
NCT00788658 Completed N/A Cognitive Behaviour Therapy for Patients With IBS December 2008 December 2010
NCT00794924 Completed N/A Probiotics and Hospital Outcome in the Elderly February 2004 January 2005
NCT00796354 Completed Phase 3 Constipation Associated With Irritable Bowel Syndrome (IBS-C) November 2008 February 2010
NCT04380090 Completed Phase 2 Post-Operative Constipation Following Total Knee Arthroplasty February 21, 2020 July 15, 2020
NCT00032682 Completed Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics March 2002 April 2006
NCT00101998 Completed Phase 2 Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication October 1, 2003 May 1, 2006
NCT00127257 Completed N/A Biofeedback for Dyssynergic Constipation September 1999 June 2006
NCT00139568 Completed Phase 3 An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation February 2005 October 2005
NCT00153114 Completed Phase 4 PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children January 2003
NCT00153127 Completed Phase 4 Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications November 2001
NCT00153140 Completed Phase 4 Polyethyleneglycol3350 vs Tegaserod in Treatment of Patients With Chronic Constipation July 2004
NCT00153153 Completed Phase 4 Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients August 2003
NCT00157638 Completed Phase 4 Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics February 2004 July 2006
NCT02116101 Completed N/A Intestinal Health and Blood Lipid Adjustment March 2013 April 2013
NCT02136693 Completed Phase 4 Psyllium Fiber Versus Placebo in Early Treatment After STARR for Obstructed Defecation: a Double-blind RCT May 2010 December 2011
NCT02137213 Completed Phase 2 Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation August 2014 March 2015
NCT02144376 Completed N/A MRI and Microbiota Analysis in Constipation March 2014 June 2016
NCT02146053 Completed Early Phase 1 Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron. March 2004 December 2004
NCT02147574 Completed Phase 4 Anti-peristaltic Ileo-sigmoid Anastomosis for the Treatment of Slow-transit Constipation:Therapeutic Evaluation December 2009 April 2014
NCT02183766 Completed Phase 1 GOS Prebiotic Effect in Children Constipation April 2010 July 2013
NCT02187640 Completed Phase 1/Phase 2 Effects of Self-administered Acupressure in Psychiatric Patients With Constipation June 2013 July 2015
NCT02189707 Completed Phase 2 Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation. August 2014 April 2015
NCT02194972 Completed Phase 3 Clinical Effects of Soluble Dietary Fiber Supplementation May 2009 October 2012
NCT02211976 Completed Phase 3 Efficacy and Tolerability of Bisacodyl Sugar Coated Tablets, Simeticone Chewing Tablets and Their Combination in Constipation and Bloatedness October 2003
NCT02215785 Completed N/A The Effect of Consumption of Kiwifruit on Constipation in Adults April 2013 October 2013
NCT02220348 Completed Phase 1 A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically July 31, 2014 May 31, 2019
NCT02228616 Completed Phase 4 Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation October 14, 2014 September 28, 2016
NCT02234518 Completed N/A Fibers and Gut Health October 2014 October 2015
NCT02236533 Completed N/A Healthy Effects of an Innovative Probiotic Pasta March 2014 March 2015
NCT02246647 Completed Biomarkers for Intestinal Permeability in Patients With Constipation September 2014 December 8, 2016
NCT02354820 Completed N/A Child Health Improvement Through Computer Automation of Constipation Management in Primary Care February 2015 December 2016
NCT02373488 Completed N/A The Effects of Connective Tissue Manipulation and Abdominal Massage in Patients With Chronic Constipation November 2014 September 2018
NCT02406859 Completed N/A Utility of an Animated Bowel Biofeedback Training Routine to Improve Bowel Function in Individuals With SCI July 1, 2013 December 29, 2017
NCT02411175 Completed Phase 2 The Efficacy of Individualised Homeopathic Treatment on Constipation October 2014 August 2015
NCT02428790 Completed Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury May 2015 November 2015
NCT02436057 Completed N/A Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform July 2014 December 2015
NCT02446080 Completed N/A Drink Milk Consumption Benefits With Culture Probiotic in the Treatment of Constipation December 2014 March 2015
NCT02459717 Completed N/A Pre-biotics and Probiotics for Constipation in Parkinson's Disease June 2015 October 2015
NCT02461485 Completed N/A Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms May 2015 October 12, 2016
NCT02467972 Completed N/A Functional Ingredients: Effect in Gastrointestinal System April 2012 December 2012
NCT02530216 Completed N/A Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes April 10, 2017 February 7, 2018
NCT02548247 Completed N/A Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation March 2011 May 2012
NCT02566746 Completed N/A Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Medical Treatment June 20, 2016 June 23, 2022
NCT02573922 Completed Phase 4 Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery May 2012 December 2014
NCT02575742 Completed Colonic Motility in Constipation and Ageing October 2015 March 2017
NCT02577471 Completed The Function of Gastrointestinal Tract During Pregnancy July 2012 October 2012
NCT02651155 Completed Phase 3 Lubiprostone for the Treatment of Chronic Idiopathic Constipation March 2, 2016 January 11, 2017
NCT02658201 Completed N/A Ultrafast MRI Imaging to Exclude Constipation September 2012 July 2017
NCT02665728 Completed Phase 2 A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects December 2015 April 2016
NCT02726295 Completed Phase 4 The Efficacy of Mutaflor(E. Coli Nissle 1917, Mutaflor®) for Chronic Constipation:Multicenter Study September 2016 October 2017
NCT02729909 Completed Phase 3 Lubiprostone for Chronic Idiopathic Constipation Treatment May 11, 2016 June 5, 2017
NCT02749682 Completed Relationship Between Constipation and Inguinal Hernia January 2015 September 2015
NCT02789111 Completed Phase 4 Trial of Alvimopan in Major Spine Surgery June 1, 2016 December 1, 2018
NCT02795390 Completed Phase 2 Clinical Trial on Palliative Cancer Patients With Constipation November 2016 August 2018
NCT02813616 Completed Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation February 2016 July 2018
NCT02819297 Completed Phase 3 BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults June 2016 June 2017
NCT02819310 Completed Phase 3 An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults June 2016 August 2017
NCT02820714 Completed Phase 2 A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation February 2016 January 2017
NCT02822508 Completed Phase 2/Phase 3 A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation June 2016 April 2017
NCT02836717 Completed Long Term Efficacy of Sacral Nerve Modulation (SNM) in Patients With Constipation or Stool Incontinence April 2016 September 2016
NCT02838797 Completed Phase 1 RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease June 2016 August 20, 2019
NCT02863848 Completed N/A Effect of Inulin-type Fructans on Constipated Children. September 2012 January 2014
NCT02867917 Completed N/A Comparison of Taste and Palatability in Fiber Supplements November 2016 December 2016
NCT02884167 Completed Multidimensional Risk Factor Assessment in Constipation June 2016 June 2017
NCT02941471 Completed Phase 1 Transabdominal Electrical Stimulation for Constipation January 2015 November 2015
NCT02956187 Completed N/A Treatment of Constipation in Functional Dyspepsia June 12, 2016 January 8, 2018
NCT02961465 Completed Effectiveness and Safety of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation February 2, 2018 December 31, 2021
NCT02961582 Completed N/A Effectiveness and Cost-effectiveness of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation February 21, 2017 December 31, 2021
NCT02977858 Completed ISE to Support Constipation Management August 30, 2016 February 5, 2020
NCT03030664 Completed N/A Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study) March 1, 2017 July 30, 2021
NCT03047629 Completed Phase 1/Phase 2 Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation May 11, 2017 June 14, 2018
NCT03051399 Completed N/A Clinical Evaluation of the Effects of EpiCor on Digestive Comfort July 6, 2015 November 30, 2016
NCT03054506 Completed N/A The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation March 7, 2017 February 1, 2019
NCT03100851 Completed Phase 3 Effect of Probiotic on Constipation August 2, 2015 March 17, 2017
NCT03103958 Completed N/A Effects of Probiotic on Modulation of the Intestinal Microbiota in Constipated Patients June 28, 2016 September 6, 2016
NCT03143517 Completed Fecal Calprotectin Collection Protocol April 19, 2017 August 23, 2018
NCT03186079 Completed Early Phase 1 Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation May 1, 2017 May 1, 2018
NCT03202576 Completed N/A Nasogastric Tube Securement Comparison Study October 1, 2016 August 20, 2020
NCT03202771 Completed N/A Randomized Controlled Trial of Home Versus Office Biofeedback for Constipation February 2007 July 2011
NCT03234452 Completed N/A Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects. March 23, 2016 April 18, 2017
NCT03263065 Completed N/A A Study of the Effect of Bran, Psyllium and Nopal on Intestinal Water Content Using Magnetic Resonance Imaging April 18, 2018 November 1, 2018
NCT03303417 Completed N/A Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers June 27, 2017 June 1, 2018
NCT03308461 Completed N/A Fecal Microbiota Transplantation for Constipation May 1, 2013 May 1, 2017
NCT03329027 Completed N/A A Pilot Study to Assess the Efficacy and Safety of Various Vibrating Capsule Modes November 14, 2017 March 30, 2018
NCT03381703 Completed Phase 1 Investigation of the Absorption, Metabolism, and Excretion and the Absolute Bioavailability of YH12852 March 16, 2017 March 29, 2017
NCT03461848 Completed N/A CYPHP Evelina London Evaluation April 9, 2018 March 31, 2022
NCT03564249 Completed N/A Magnetic Resonance Imaging in Paediatric Constipation April 15, 2018 June 30, 2019
NCT03751267 Completed N/A Effects of Paediatric Tuina (Massage) on Constipation and Related Symptoms Among the Pre-school Aged Children June 12, 2018 December 30, 2018
NCT03764995 Completed N/A The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation December 10, 2018 May 16, 2019
NCT03781791 Completed Phase 2 Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET) December 10, 2018 December 14, 2021
NCT03845673 Completed N/A Fiber Regimens for Constipation Symptoms July 2003 July 2005
NCT03937739 Completed Nutrition and Constipation at Inguinal Hernia Patients March 1, 2018 April 1, 2019
NCT04014816 Completed Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients January 1, 2015 July 1, 2015
NCT04032262 Completed N/A Parkinson's Disease and Digestive Health October 4, 2017 December 30, 2021
NCT04035616 Completed N/A Probiotics in Elderly Patients With Medical Conditions September 1, 2018 December 31, 2018
NCT04060121 Completed Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders June 1, 2018 November 29, 2022
NCT04068415 Completed Development of a Constipation Risk Assessment Scale for Hospitalized Patients. May 6, 2012 April 16, 2014
NCT04159350 Completed N/A Point-of-care Anorectal Testing to Predict Outcomes With Biofeedback Therapy: Clinical Trial June 15, 2020 September 13, 2021
NCT04197869 Completed Phase 4 Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy December 9, 2019 June 21, 2023
NCT04262648 Completed N/A Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in Newborns March 3, 2020 May 16, 2022
NCT04262752 Completed N/A MOWOOT Device to Treat Constipation in Adults January 11, 2018 June 7, 2019
NCT04283266 Completed N/A Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults June 12, 2016 January 31, 2019
NCT04304170 Completed N/A Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit February 21, 2017 March 15, 2018
NCT04307121 Completed Association of Constipation Inflammatory and Microbial Translocation Markers March 10, 2020 December 31, 2020
NCT04309019 Completed Constipation, Gut Microbiome, and Microbial-derived Uremic Toxins From the Gut Microbiota in HD Patients March 10, 2020 December 31, 2020
NCT04373772 Completed N/A Effect of Abdominal Massage on Bowel Evacuation After Cranial Surgery July 1, 2015 February 28, 2016
NCT00006157 Completed Phase 3 Treatment of Functional Bowel Disorders July 1996 March 2001
NCT04382456 Completed N/A Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation June 1, 2020 September 7, 2020
NCT04415710 Completed Pelvic Floor and Sexual Dysfunction in Women With Sjogren's Syndrome February 21, 2019 June 2, 2020
NCT04451096 Completed Phase 3 Probiotics-prebiotic Fiber Therapy in Parkinson's Disease Patients With Constipation October 6, 2018 February 28, 2019
NCT04457791 Completed N/A Improving Constipation by Stimulating Fiber Intake Using Personalized Dietary Advice August 31, 2020 November 2, 2020
NCT04462211 Completed N/A Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Patients August 1, 2019 March 1, 2020
NCT04501263 Completed Educational Intervention for Management of Constipation October 1, 2018 March 31, 2020
NCT04513093 Completed N/A Aromatherapy Massage Applied on Constipation January 14, 2018 May 21, 2020
NCT04534036 Completed N/A Tolerability and Functional Assessment of a Novel Children's Synbiotic August 13, 2020 February 10, 2022
NCT04534465 Completed Phase 4 Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements. February 13, 2013 March 19, 2013
NCT04590846 Completed N/A A Caregiver-mediated Health Educational Intervention to Improve Constipation Status of Primary School Children October 7, 2020 December 31, 2020
NCT04667884 Completed N/A Effects of Prebiotic or Probiotic Supplements on Symptoms of Functional Constipation August 15, 2020 September 30, 2021
NCT04671030 Completed Phase 1 Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI January 15, 2018 June 3, 2021
NCT04677634 Completed N/A Open Label Tolerability Study of ISOThrive Prebiotic Nectar (MIMO) in Subjects With Constipation October 14, 2020 April 2, 2021
NCT04798417 Completed N/A Nutrition to Relieve IBS Constipation March 8, 2021 July 15, 2021
NCT04873466 Completed N/A The Effects of Enzyme-rich Malt Extract on Chronic Constipation March 1, 2021 March 1, 2022
NCT04882995 Completed N/A Effect of Preoperative Fiber on Postoperative Bowel Function May 13, 2019 June 1, 2021
NCT04953728 Completed N/A Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C July 1, 2021 December 5, 2022
NCT04996186 Completed Symptoms and Treatment Assessment of Ano-Rectal Disorders in Multiple Sclerosis Patients : STAR-Q June 1, 2019 April 30, 2021
NCT05025553 Completed N/A Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children January 1, 2018 February 1, 2021
NCT05059756 Completed N/A PTNS and PFR in the Treatment of Childhood Constipation May 8, 2019 December 8, 2021
NCT05247333 Completed N/A Implementation of a Minor Ailment Service in Community Pharmacy Practice October 1, 2020 September 30, 2023
NCT05286476 Completed N/A Effect of 6 Weeks of Whole-body Vibration in Treatment of Postnatal Constipation October 10, 2019 March 25, 2021
NCT05287789 Completed N/A Effectiveness of Squatting Position on Constipation Severity and Defecation Problems January 1, 2018 May 31, 2018
NCT05309837 Completed N/A Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects November 2012 September 19, 2013
NCT05314335 Completed N/A Reflexology Socks and Opioid-induced Constipation October 30, 2020 July 7, 2022
NCT05336305 Completed N/A Polydextrose for Patients With Chronic Kidney Disease March 30, 2021 October 30, 2021
NCT05341180 Completed Phase 2/Phase 3 Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial May 27, 2022 July 22, 2023
NCT05343910 Completed N/A The Effect of Aroma Massage on Constipation December 1, 2012 March 1, 2013
NCT05447403 Completed N/A Effect of Chewing Gum and WeChat Enhanced Instructions on the Bowel Preparation Quality in Patients With Constipation February 24, 2022 August 30, 2023
NCT05473546 Completed Diarrhea and Stipsis in Critically Ill Patients (NUTRITI) October 11, 2019 July 22, 2022
NCT05508022 Completed N/A Determining the Effect of Breathing Exercise Applied to Children Aged 6-12 Before Enema on Anxiety, Fear and Pain May 9, 2023 June 15, 2023
NCT05517460 Completed N/A The Efficacy of Auricular Acupressure on Improving Constipation Among Residents in Community Rehabilitation Center September 6, 2022 March 15, 2023
NCT05580679 Completed N/A Effect of Abdominal Massage on Palliative Care Patients March 15, 2022 December 30, 2022
NCT05612646 Completed N/A The Effect of Acupressure in Improving Constipation Among Inpatients in Neurology Departments September 11, 2020 October 24, 2022
NCT05614726 Completed N/A A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study June 18, 2021 March 17, 2022
NCT05683743 Completed The Incidence, Risk Factors, and Effects of Constipation in Critical Patients December 1, 2018 July 22, 2019
NCT05982743 Completed N/A Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in Vietnam May 11, 2022 March 8, 2023
NCT05983926 Completed N/A To Explore the Changes of Nutritional Status, Immune Function, Intestinal Motility and Intestinal Flora in Patients With Constipation Before and After Surgical Treatment January 1, 2020 June 30, 2023
NCT05988502 Completed N/A Auricular Acupressure Relieves Constipation for Patients With Heart Failure in Hospital March 6, 2022 October 30, 2022
NCT06155929 Completed N/A Traveler's Constipation May 2, 2023 May 20, 2023
NCT06198244 Completed N/A Effect of Transcutaneous Electrical Stimulation on Constipation December 1, 2023 February 5, 2024
NCT06285851 Completed N/A A Novel Iron Supplement for Athletes: Phase I November 23, 2023 December 12, 2023
NCT06303011 Completed N/A Abdominal Massage With TENS on Parasacral Versus Sacral Area on Symptom,Severity & QOL in Chronic Constipation Females. March 15, 2023 March 15, 2024
NCT06385561 Completed Phase 2 The Influence of Tramadol on Opioid-induced Bowel Dysfunction August 11, 2022 May 15, 2023
NCT06399133 Completed N/A Care Package for Postoperative Constipation January 1, 2023 April 3, 2023
NCT06401460 Completed N/A Yannianjiuzhuan Method and Reverse Breathing Training to Improve Constipation in Elderly Patients With Coronary Heart Disease November 1, 2021 June 30, 2023
NCT06464484 Completed N/A The Effects Of Probiotics On Stress Among Healthy Adults From Umm Al-Qura University At Makkah January 26, 2023 April 30, 2024
NCT00804141 Completed Phase 3 Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation December 3, 2008 September 20, 2010
NCT00844831 Completed Phase 4 Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit May 2009 May 2011
NCT00846794 Completed AcuGraph and Digestive Symptoms February 2009 March 2010
NCT00849628 Completed Use of Drugs and Constipation in Nursing Homes June 2008 February 2010
NCT00869830 Completed N/A The Effectiveness of Biofeedback Treatment in Constipated Patients With Idiopathic Parkinson's Disease January 2007
NCT00888147 Completed Fiber Formula Study Among Radiation Oncology Patients April 2009 July 2011
NCT00902031 Completed N/A Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients April 2006 October 2010
NCT00903747 Completed Phase 1 Thorough Corrected QT Interval (QTc) Study To Evaluate Possible Effects of Prucalopride on ECG Parameters January 2009 May 2009
NCT00909116 Completed International Multicenter Prospective Transtar Registry January 31, 2009 April 30, 2012
NCT00931853 Completed Phase 3 Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC). September 2010 December 2011
NCT00936884 Completed Phase 3 Study Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-Constipation July 2009 November 2013
NCT00982839 Completed Phase 2 Rectal Sensory Training - A Study of Two Techniques March 2004 July 2014
NCT00988286 Completed N/A Mechanism of Action of Biofeedback Therapy August 2005 January 2016
NCT00992576 Completed Phase 2/Phase 3 Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain January 2010 January 2012
NCT00994851 Completed Phase 3 Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment. September 2009 August 2012
NCT01004393 Completed Phase 2 Methylnaltrexone for Opioid-induced Constipation in Cancer Patients October 2009 December 2013
NCT01007123 Completed Phase 2 Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation November 2009 October 2010
NCT01102036 Completed N/A Effects of Cultura Yoghurt in Relation to Transit Time and Digestive Discomfort in Healthy Women and Men February 2010 June 2010
NCT01116206 Completed Phase 3 An Efficacy and Safety Study of Prucalopride in Participants With Chronic Constipation May 2010 March 2011
NCT01161784 Completed Phase 3 The Effects of a Probiotic Fermented Milk on Functional Constipation in Adults January 2010 June 2010
NCT01162863 Completed N/A Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation November 2010 December 2012
NCT01170039 Completed Phase 4 The Effectiveness of Lubiprostone in Constipated Diabetics September 2010 October 2014
NCT01180725 Completed Phase 4 Investigation of Dried Plums in the Treatment of Adults With Constipation
NCT01212445 Completed Phase 2 Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515) October 2010 November 2011
NCT01236534 Completed Phase 4 Lubiprostone in Patients With Multiple Sclerosis Associated Constipation November 2010 April 2012
NCT01251822 Completed Phase 3 Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation November 2010 December 2011
NCT01267370 Completed Phase 4 Soy Polysaccharide Fiber for the Treatment of Chronic Constipation in Children: a Randomized, Double-blind Trial January 2002 October 2003
NCT01275755 Completed Phase 2 Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain January 19, 2011 July 15, 2011
NCT01288508 Completed N/A Investigation of Supra Fiber in the Treatment of Adults With Constipation October 2010 September 2014
NCT01300884 Completed Sierra High Definition Ano-Rectal Manometry February 2008 December 2011
NCT01301781 Completed Phase 2 BLI801 Laxative in Constipated Adults January 2011
NCT01306448 Completed N/A Safety Evaluation of the Vibrating Capsule March 2011 April 2014
NCT01333787 Completed Phase 4 Dietary Fiber Mixture in Constipated Pediatric Patients February 2008 December 2010
NCT01335386 Completed Phase 2 Investigation of KLYX in Patients With Constipation April 2010 July 2010
NCT01354080 Completed N/A The Effectiveness of Massage in Treating Constipation June 2007 March 2010
NCT01375712 Completed N/A Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects June 2011 October 2011
NCT01399294 Completed Cross Sectional Study of Constipation in Advanced Cancer Patients May 2010 February 2011
NCT01411501 Completed Phase 3 Efficacy and Safety of Acupuncture for Functional Constipation September 2011 December 2014
NCT01416909 Completed N/A Managing Medication-induced Constipation in Cancer: A Clinical Trial November 2008 January 2014
NCT01424228 Completed Phase 4 Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years April 6, 2011 December 19, 2012
NCT01438567 Completed Phase 3 A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy September 2011 September 2014
NCT01447849 Completed Phase 2/Phase 3 Lubiprostone and Mucus Secretion in Patients With Chronic Constipation August 2011 November 2012
NCT01463293 Completed Phase 3 B. Lactis HN019 for Functional Constipation March 2012 May 2013
NCT01474499 Completed Phase 3 A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation September 2011 May 2012
NCT01513811 Completed Phase 2 Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective February 2010 December 2011
NCT01515501 Completed N/A Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial) October 2007 August 2018
NCT01523288 Completed The Intestinal Function in People With Prader-Willi Syndrome February 2011 January 2012
NCT01566409 Completed N/A Maintenance Treatment for Children With Constipation September 2013 September 2015
NCT01582659 Completed N/A Outpatient Treatment of Constipation in Children June 2012 October 2014
NCT01592734 Completed Phase 4 Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children May 2010 November 2011
NCT01603719 Completed N/A Efficacy and Safety of an Infant Formula With Milkfat and Prebiotics August 2011 January 2020
NCT01607060 Completed Phase 3 Impact of Laxative Therapy With Lactulose in the Evolution of Organ Dysfunction in Critically Ill Patients. September 2008
NCT01609608 Completed N/A Whole-Body Vibration for Functional Constipation October 2009 November 2010
NCT01618292 Completed Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy January 2007 August 2012
NCT01629303 Completed Phase 2 Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation June 2012 January 2015
NCT01642914 Completed Phase 3 Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating August 2012 August 2013
NCT01655771 Completed Phase 1 TD-1211 Single-Dose Study in Elderly and Young Healthy Subjects August 2012 March 2013
NCT01670669 Completed Phase 1 Prucalopride in Paediatric Subjects, With Functional Faecal Retention November 1998 July 1999
NCT01674166 Completed Phase 1 Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention November 1998 May 1999
NCT01674192 Completed Phase 1 Prucalopride Subjects With Renal Impairment July 1997 August 1999
NCT01677715 Completed N/A Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System August 2011 March 2012
NCT01680432 Completed N/A Effect of the Consumption of a Cheese Enriched With Probiotic Organisms in Improving Symptoms of Constipation January 2012 May 2012
NCT01682798 Completed N/A Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System May 2009 July 2009
NCT01687985 Completed Phase 2 A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults August 2012 March 2013
NCT01695915 Completed Diurnal Variation in Rectal Diameter September 2012 October 2012
NCT01710579 Completed N/A Normal Values in Ano-rectal 3D High Resolution Manometry September 2012 September 2014
NCT01726504 Completed Phase 2 The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation October 2012 December 2014
NCT01726751 Completed Phase 1/Phase 2 Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome August 2005 April 2014
NCT01773096 Completed Phase 4 Methylnaltrexone Use for Opioid-induced Postoperative Constipation May 2013 May 2015
NCT01781104 Completed Phase 2 Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation March 2013 October 2014
NCT01802112 Completed N/A Randomised Controlled Trial of Efficacy of Resistant Maltodextrins on Reducing Colonic Transit Time February 2013 June 2013
NCT01809587 Completed Phase 3 IQP-PO-101 for the Regulation of Bowel Movement Frequency March 2013 August 2013
NCT01810653 Completed Phase 4 A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation April 2006 December 2008
NCT01825434 Completed N/A Effect of Yogurt With Polydextrose,L Acidophilus and B Lactis in Chronic Constipation February 2010 June 2010
NCT01834729 Completed Phase 2 Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions March 2013 September 6, 2017
NCT01837940 Completed Phase 3 Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population April 2013 September 2013
NCT01859065 Completed N/A "Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits" December 2011 April 2012
NCT01862341 Completed N/A The Effect of Milk Powder With Fiber and Probiotics on Digestive Habits and General Health Well-being of Selected Filipino Mothers. May 2013 July 2013
NCT01867944 Completed N/A Perineal Self-Acupressure June 2013
NCT01874301 Completed N/A Probiotics and Gut Health November 2013 October 2015
NCT01879605 Completed Phase 4 Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery December 2007 December 2009
NCT01880294 Completed A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia March 2013 December 2013
NCT01885104 Completed Phase 2 Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003) April 2013 October 2013
NCT01890616 Completed Constipation and Gut Transit in DMD Patients May 1, 2013 July 1, 2015
NCT01902537 Completed An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation August 2012 April 2013
NCT01911559 Completed Effectiveness of Standing Frame on Constipation in Children With Cerebral Palsy January 2013 February 2015
NCT01917773 Completed Phase 4 Effect of Octreotide on the Colonic Motility in Pediatric Patients August 2013 June 2014
NCT01983306 Completed Phase 2 Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) November 2013 April 2015
NCT01985867 Completed N/A Lcr35 for Children With Functional Constipation November 2013 November 2016
NCT02004288 Completed N/A The Role of Lactobacillus Reuteri in Children and Adolescents With Anorexia Nervosa December 2013 September 2016
NCT02012543 Completed N/A Effect of Agar Administration on Defecation and Fecal Condition in Chronic Constipated Patients November 2013 October 2014
NCT02047045 Completed N/A Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial April 2014 May 2017
NCT02073006 Completed Phase 2/Phase 3 A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation February 2014 October 2014
NCT02082457 Completed Phase 2 Efficacy and Safety of YKP10811 in Subjects With Irritable Bowel Syndrome With Constipation December 2013 December 2014
NCT02091115 Completed Phase 1/Phase 2 Consumption of Milk Drink and Constipation July 2013 September 2013
NCT02110719 Completed Phase 4 Decreasing Narcotics in Advanced Pelvic Surgery March 2014 June 2016
NCT05899062 Enrolling by invitation N/A Telerehabilitation-based Exercise Training in Constipated Patients June 1, 2023 February 29, 2024
NCT06352827 Enrolling by invitation Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation June 2024 April 2026
NCT01210625 No longer available Starch-entrapped Microspheres [Nutrabiotix Fiber] for Gut Health
NCT06100055 Not yet recruiting N/A The ReVo Study: Low-volume vs High-volume Rectal Irrigation March 2024 July 2025
NCT06298331 Not yet recruiting N/A Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Constipation March 15, 2024 March 15, 2026
NCT06073249 Not yet recruiting N/A Comparison of the Efficacy of Different Nerve Stimulation Methods in Individuals With Chronic Consipation October 15, 2023 June 10, 2024
NCT05906186 Not yet recruiting Study Intestinal Complaints During Chemotherapy. September 1, 2023 May 30, 2024
NCT05455853 Not yet recruiting N/A Effect of Bilateral Transcutaneous Tibial Nerve Stimulation on Postpartum Constipation August 1, 2022 November 1, 2022
NCT05528146 Not yet recruiting N/A Effects of Psyllium on Constipation in Schizo-phrenic: A Randomized Controlled Crossover Trial December 1, 2022 August 31, 2023
NCT06432608 Not yet recruiting N/A Efficacy of Lacticaseibacillus Paracasei Strain Shirota on Clinical Manifestation of Functional Constipation in Mexican Adults June 15, 2024 November 25, 2025
NCT05946967 Not yet recruiting N/A Colon Transit Study for Chronic Constipation Assessment and Therapy by Biofeedback With and Without TENS July 20, 2023 December 31, 2023
NCT04623359 Not yet recruiting N/A Usefulness of High Resolution Manometry in Constipation January 2021 September 2024
NCT05805787 Not yet recruiting N/A Acupressure for Constipation in the Elderly April 2023 July 2023
NCT05773742 Not yet recruiting N/A Treatment of Fecal Incontinence and Chronic Constipation With Low-volume Irrigation April 11, 2023 March 1, 2025
NCT06294457 Not yet recruiting N/A Effectiveness of Non-invasive Neuromodulation for Intestinal Transit in Healthy Subjects March 2024 June 2024
NCT06159777 Not yet recruiting Phase 4 Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery August 2024 February 2025
NCT06335797 Not yet recruiting N/A Optimization of Postoperative Bowel Habits August 2024 December 2025
NCT04666155 Not yet recruiting N/A MOWOOT Device Treatment for Adults With Chronic Constipation February 29, 2024 May 2025
NCT04525248 Not yet recruiting N/A Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation September 1, 2020 August 1, 2024
NCT05530681 Not yet recruiting N/A Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth September 1, 2022 September 1, 2025
NCT04253652 Not yet recruiting Investigating the Effects of Iron on the Gastrointestinal Tract March 9, 2023 December 2024
NCT06290830 Not yet recruiting N/A Abdominal Massage and Kegel Exercises on Constipation and Quality of Life in Female Students March 15, 2024 June 1, 2024
NCT05655845 Recruiting Risk Factors for Bowel Dysfunction at Preschool and Early Childhood Age in Children With Hirschsprung Disease August 20, 2022 August 30, 2023
NCT06334198 Recruiting Phase 2 The Effect of Naldemedine on Opioid-induced Bowel Dysfunction March 12, 2024 March 2025
NCT05833191 Recruiting N/A Efficacy of Different Nerve Stimulation Methods in Individuals With Chronic Constipation April 15, 2023 August 15, 2023
NCT06390761 Recruiting N/A Efficacy of Acupuncture for the Treatment of Parkinson's Disease Related Constipation April 30, 2024 December 30, 2027
NCT04506593 Recruiting Indiana University Gastrointestinal Motility Diagnosis Registry November 2014 November 2024
NCT05734833 Recruiting N/A Do Probiotics Improve Recovery From Acute Constipation in Kids? April 22, 2023 September 22, 2025
NCT06292949 Recruiting N/A Clinical Study of Resistant Starch in Improving Constipation September 27, 2023 September 25, 2024
NCT04014413 Recruiting N/A Safety and Efficacy of Fecal Microbiota Transplantation July 15, 2019 October 31, 2030
NCT05461924 Recruiting The Long Term Outcomes After Pull-through of Long Segment Hirschsprung Disease July 15, 2022 August 20, 2023
NCT03909204 Recruiting N/A LAPEC for the Treatment of Severe Constipation May 20, 2019 May 12, 2023
NCT03842007 Recruiting N/A Understanding Mechanisms of Normal and Disordered Defecation January 29, 2019 June 2024
NCT06234865 Recruiting N/A Technology-based Constipation Prevention Training February 8, 2024 November 2024
NCT06353841 Recruiting N/A Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children May 3, 2023 December 31, 2024
NCT04644133 Recruiting Electronic Mobile Phone App Stool Diary December 6, 2018 March 31, 2024
NCT02234219 Recruiting N/A Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled Trial November 30, 2019 October 30, 2024
NCT06156995 Recruiting N/A Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation January 1, 2023 December 31, 2023
NCT05895877 Recruiting Phase 3 Evaluate the Efficacy and Safety of Goofice® (Elobixibat) in Patients With Chronic Constipation December 21, 2021 September 30, 2023
NCT06351852 Recruiting Early Phase 1 Transdermal Administration by a Novel Wireless Iontophoresis Device March 22, 2022 February 15, 2025
NCT02877394 Recruiting Phase 2 Use of a Squatting Assist Device in Patients With Constipation September 1, 2016 December 2024
NCT05750186 Recruiting N/A The Effect of Abdominal Massage Applied After Surgery October 1, 2022 August 1, 2023
NCT06154525 Recruiting N/A Effectiveness of Bacillus Spore Probiotics in Reducing Constipation, Anorexia, and Slow Weight Gain in Children March 10, 2024 July 30, 2024
NCT04684849 Recruiting Assessment and Validation of Electronic Gas and Bloating Diary September 10, 2020 August 31, 2024
NCT04102527 Recruiting Evaluation of the Impact of Transit Troubles in Patients Undergoing Peritoneal Dialysis December 19, 2019 December 31, 2024
NCT06123195 Recruiting N/A Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial February 1, 2024 July 2025
NCT06122571 Recruiting N/A A Clinical Trial to Evaluate the Effect of ConcenTrace Trace Mineral Drops on Gut Health October 5, 2023 January 31, 2024
NCT06106685 Recruiting Phase 1/Phase 2 Washed Microbiota Transplantation for Chronic Constipation in Adults July 24, 2023 December 2026
NCT05989763 Recruiting N/A Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis February 17, 2024 September 1, 2029
NCT04861233 Recruiting A Study of Lubiprostone to Treat Constipation September 1, 2021 November 30, 2024
NCT05805436 Recruiting Phase 4 Preop Laxatives in Robotic Urologic Surgery June 1, 2023 March 3, 2025
NCT03031301 Recruiting N/A A Study to Assess the Efficacy and Safety of the Vibrant Capsule Administered 5 Times Per Week February 1, 2017 July 2018
NCT06073262 Recruiting Investigation of Low Back Pain Level on Symptoms in Chronic Consipation October 3, 2023 December 21, 2023
NCT04263896 Recruiting Phase 4 Bowel Function After Minimally Invasive Hysterectomy August 28, 2019 June 30, 2025
NCT05807321 Recruiting N/A Fecobionics in Biofeedback Therapy in Dyssynergia Patients August 15, 2023 March 31, 2025
NCT02344485 Recruiting N/A Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease January 1, 2015 December 31, 2024
NCT06311097 Recruiting N/A Dairy Products to Your Gut and Brain April 8, 2024 September 2025
NCT05603715 Recruiting Phase 2 Pyridostigmine for the Treatment of Constipation in Parkinson Disease August 10, 2022 December 2024
NCT05821309 Recruiting Phase 4 Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen June 8, 2023 July 2024
NCT05823259 Recruiting N/A The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes May 30, 2023 December 1, 2024
NCT00990951 Suspended Phase 3 Study of Efficacy of Association of Senna Alexandrina Mill and Associations on Functional Intestinal Constipation June 2010 July 2014
NCT00563758 Terminated N/A A Randomized, Double-blind, Placebo-controlled Multicenter Study to Assess the Efficacy, Safety and Tolerability of Tegaserod 2 mg Bid vs Placebo in Patients With Chronic Constipation December 2004 February 2006
NCT00669461 Terminated N/A Lubiprostone as a Treatment for Constipation in Parkinson's Disease June 2009 September 2010
NCT01003249 Terminated Phase 4 Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen September 2009 March 2013
NCT00653887 Terminated N/A Biofeedback and Cortical Excitability January 2008 December 2009
NCT01014559 Terminated Phase 3 Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients February 2010 February 2013
NCT01096290 Terminated Phase 4 Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications April 2010 September 2012
NCT01114997 Terminated Phase 4 Effect of Lidocaine and Esmolol to Improve the Quality of Recovery April 2010 June 2015
NCT04471857 Terminated N/A Hypnosis for Children Undergoing Anorectal Manometry January 9, 2017 March 4, 2020
NCT02609607 Terminated Phase 2 Treating Anorectal Dysfunction in MS June 2016 December 2018
NCT04483479 Terminated Phase 2 Orally Administered ENT-01 for Parkinson's Disease-Related Constipation Follow-on Safety "Roll-over" Study (Rollover) July 30, 2020 February 17, 2022
NCT01189409 Terminated Phase 4 Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients June 2010 October 2018
NCT02745353 Terminated Phase 2 Naloxegol in Cancer Opioid-Induced Constipation May 2016 June 22, 2017
NCT02829047 Terminated N/A Tolerability, Safety and Efficacy of a New Frequency of Vibrant Capsule Administration August 2016 March 2017
NCT02839889 Terminated Phase 4 Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation) September 2016 January 11, 2018
NCT00219518 Terminated Mechano-physiological Approach to Anorectal Function February 2006 May 2011
NCT02946580 Terminated Phase 4 Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients January 2017 February 2018
NCT04759833 Terminated Phase 3 A Study of Prucalopride For Functional Constipation in Children and Teenagers July 13, 2021 November 13, 2023
NCT02977286 Terminated Phase 4 Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids January 1, 2017 October 9, 2019
NCT00365820 Terminated Phase 2/Phase 3 Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain July 2006 April 2007
NCT00536523 Terminated Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer April 2007 December 2009
NCT00577499 Terminated Effect of Lubiprostone on Nutritional Status and Pulmonary Function in Adults With Cystic Fibrosis October 2007 June 2009
NCT03523715 Terminated Phase 4 Prunes for Gastrointestinal Function After Gynecologic Surgery November 30, 2017 July 31, 2020
NCT01955213 Terminated Methylnaltrexone for Opioid Induced Constipation July 2012 September 2017
NCT00331045 Terminated Phase 2 Clinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid April 2006 December 2006
NCT00799201 Terminated Phase 4 Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients August 2007 October 2012
NCT00467350 Terminated N/A Comparison Trial of Enema vs. PEG 3350 for Constipation December 2006 May 2009
NCT03148002 Unknown status Phase 4 Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation July 7, 2017 February 1, 2018
NCT01286376 Unknown status Phase 3 Evaluating the Effectiveness of LACTOFOS in Constipated Patients August 2010 August 2011
NCT01039051 Unknown status Phase 2/Phase 3 Diet and Lifestyle Intervention Study in Postpartum Women in China June 2009 June 2010
NCT04129788 Unknown status Phase 4 MRI Assessment of Mode of Action of Bisacodyl, Multiple Doses November 4, 2020 July 31, 2022
NCT04132661 Unknown status Phase 4 MRI Assessment of Mode of Action of Bisacodyl, Single Dose September 25, 2020 July 31, 2022
NCT04148248 Unknown status A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation March 2, 2020 July 2023
NCT00563615 Unknown status N/A Study of Effect of Tegaserod on Small and Large Bowel Transit by Scintigraphic Method November 2004 October 2006
NCT03046563 Unknown status N/A The Applying of Acupressure and Abdominal Massage to Improving Constipation in Stroke Patients. November 2015 May 2017
NCT04318808 Unknown status N/A Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer March 1, 2020 August 2022
NCT02958566 Unknown status Phase 4 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery January 2017 December 2018
NCT05037565 Unknown status N/A Effectiveness of Partially Hydrolyzed Guar Gum in Improving Fecal Characteristics in Long Term Care Facility Residents January 2022 July 2022
NCT01734226 Unknown status Phase 2/Phase 3 Efficacy and Safety of Prunus Mume Extract on Improvement of Constipation August 2012 December 2012
NCT03177434 Unknown status Phase 4 Efficacy of Dicopeg Junior in Comparison With Lactulose for the Treatment of Functional Constipation in Children Aged 6 Months to 6 Years. February 2016 May 2018
NCT01629147 Unknown status N/A Treatment of Chronic Constipation in Children With Lactobacillus Reuteri July 2014 September 2016
NCT02949882 Unknown status Phase 4 Improving Bowel Habits of Elderly With Probiotics and Non-probiotics April 2017 August 2017
NCT02842411 Unknown status Risk Factors for Inadequate Bowel Preparation in Patients With Chronic Constipation August 2016 January 2017
NCT04661202 Unknown status N/A Effects of Exercise Training on Pelvic Floor Symptoms and Function in Adults With Constipation January 1, 2021 August 2022
NCT03316859 Unknown status Phase 2/Phase 3 Naloxegol and Opioid-induced Constipation November 6, 2017 December 1, 2022
NCT01863303 Unknown status Epidemiological Study of Colorectal Cancer in WuHan June 2012 June 2018
NCT03317938 Unknown status N/A Studies in Patients With Defecatory Disorders August 14, 2017 December 31, 2023
NCT01875744 Unknown status Phase 4 Polyethylene Glycol for Childhood Constipation June 2013
NCT05324241 Unknown status N/A Laxative Properties of Microencapsulated Lipid (Constipation Study) April 15, 2022 April 15, 2023
NCT05330728 Unknown status N/A Comparison of the Effects of Abdominal Massage and Kinesio Taping in Women With Chronic Constipation June 15, 2022 June 15, 2023
NCT00892086 Unknown status Prevalence and Recognition of Geriatric Syndrome in Outpatient Clinic at Srinagarind Hospital May 2009 May 2010
NCT04293159 Unknown status N/A Effect of Probiotic on Constipation in Patients With Parkinson's Disease May 14, 2019 June 2023
NCT04627168 Unknown status N/A Trancutaneous Abdominal Stimulation on Bowel Function. October 7, 2020 February 28, 2023
NCT03565848 Unknown status Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis May 1, 2022 May 1, 2024
NCT00857363 Unknown status Colonic Transit Time Validation Study March 2009 June 2009
NCT03591393 Unknown status N/A Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function August 1, 2018 June 30, 2021
NCT04625881 Unknown status Phase 3 Effects of an Apple Derived Fibre Supplement on Constipation October 1, 2020 January 31, 2021
NCT02255747 Unknown status N/A Anal Dilatation for Infants and Children With Constipation September 2014 October 2016
NCT02812836 Unknown status N/A 3D High Resolution Manometry and Balloon Expulsion Test in Diagnosis of Dyssynergic Defecation in Children March 1, 2018 March 1, 2019
NCT02812823 Unknown status N/A Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children March 1, 2018 March 2019
NCT02067546 Unknown status N/A Innovative Toilet Seat Test for Patients With Symptoms of Constipation and/or Emptying Disorders March 2014
NCT02805959 Unknown status Colonic Motility in Constipation and Aging: A Study With a New 3D Transit System June 2016
NCT01300897 Unknown status Investigation of Cortico-Rectal Pathways in Healthy Subjects and Constipated Patients August 2005 December 2018
NCT02772692 Unknown status N/A Defecation Postures for Functional Consumption May 2016 January 2017
NCT03941925 Unknown status N/A Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits July 1, 2019 December 2022
NCT03981510 Unknown status N/A Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation June 13, 2019 December 2023
NCT01295138 Unknown status N/A Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation February 2011 July 2012
NCT04527640 Unknown status N/A Effects of Synbiotics Supplementation on the Uremic Toxin Indoxyl Sulfate Level and Constipation in End-stage Renal Disease Patients Undergoing Hemodialysis September 15, 2020 February 28, 2021
NCT02395484 Unknown status Metagenome Analysis of Gut Microbiota in CC Patients March 2015 June 2016
NCT01786837 Withdrawn N/A Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation December 2012 October 2015
NCT05321953 Withdrawn N/A The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation May 26, 2022 May 10, 2023
NCT05082129 Withdrawn N/A Magnetic Resonance Imaging in Paediatric Constipation (MAGIC2) July 12, 2021 July 12, 2023
NCT02459808 Withdrawn Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome May 2015
NCT02895516 Withdrawn Phase 2 Ease of Use, Tolerability, Efficacy and Safety of the Vibrant Capsule Administered in the Home Environment October 2016 May 2017
NCT03342287 Withdrawn Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation March 2016 March 2021
NCT01452386 Withdrawn Modified Functional Magnetic Stimulation Treatment for Constipation Improvement June 2011 June 2016
NCT02292459 Withdrawn Phase 3 Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005) December 2015 December 2015
NCT00985569 Withdrawn Surveying The Outcomes Of Lubiprostone (The STOOL Study) in Nursing Home Residents November 2009 November 2010
NCT04768010 Withdrawn Early Phase 1 Misoprostol for Bloating and Distension August 2023 September 18, 2023
NCT02705378 Withdrawn Phase 3 The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit May 2017 December 2019
NCT01869751 Withdrawn The Colonic Transit Time: a Modifiable Determinant of Intestinal Production and Uptake of Microbial Metabolites? May 2013 December 2018
HPO alt_id (Human Phenotype Ontology)
HP:0002241
HPO alt_id (Human Phenotype Ontology)
HP:0003786
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0002019
ICD10 preferred id (Insert disease from ICD10)
D0008765
ICD10 class code (Insert disease from ICD10)
K59.0
MeSH unique ID (MeSH (Medical Subject Headings))
D003248