heart valve disease

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Information
Disease name
heart valve disease
Disease ID
DOID:4079
Description
"A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right)." [url:http\://en.wikipedia.org/wiki/Heart_valve_disease]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00291525 Active, not recruiting N/A Randomized On-X Anticoagulation Trial June 6, 2006 December 31, 2022
NCT00639782 Completed N/A Prospective Randomized On-X Versus SJM Evaluation Trial July 2003 May 1, 2021
NCT02671474 Completed N/A Valve Leaflet Motion in Sutureless Bioprosthetic Aortic Valves January 2016 May 2016
NCT02587039 Completed N/A An Intervention to Reduce Delirium After Cardiac Surgery June 2014 December 2015
NCT01384643 Completed Phase 4 Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery May 2011 May 2012
NCT01426776 Completed N/A Effect of Heart Valve Replacement on Cheyne-Stokes Respiration September 2010 July 2012
NCT01558765 Completed Phase 2 CopenHeartVR - Integrated Rehabilitation of Patients After Heart Valve Surgery March 2012 May 2015
NCT00581399 Completed Phase 2 A Randomized Multicenter Clinical Study On the High Vacuum Body Cavity Drainage System Following Open Heart Surgery September 2006 September 2010
NCT01996657 Completed D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement January 2013 June 2016
NCT02035540 Completed European Clinical Study for the Application of Regenerative Heart Valves - ESPOIR August 2014 January 2017
NCT02867930 Completed Phase 4 Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography June 2016 December 30, 2016
NCT02527629 Completed Aortic Replacement Using Individualised Regenerative Allografts - ARISE (the "Surveillance") September 2015 March 2019
NCT02790008 Completed Magnetic Resonance Imaging and Fibrosis June 2015 January 2021
NCT01023152 Completed N/A Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass
NCT01178710 Completed N/A Effect of Simvastatin on Cardiac Function September 2010 July 2012
NCT01210976 Completed Phase 4 The Effects of Levosimendan on Haemodynamics in Patients Undergoing Elective Aortic Valve Replacement (AVR)Together With Coronary Artery Bypass Grafting (CABG) Surgery January 2009 September 2010
NCT01348074 Completed Phase 2 Reinitiation of Anticoagulation After Temporary Withdrawal of Vitamin K Antagonist April 2011 December 2013
NCT06027788 Recruiting N/A CTSN Embolic Protection Trial September 6, 2023 April 1, 2027
NCT01653223 Recruiting N/A Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery January 2013 December 2026
NCT00700947 Terminated Phase 1 Using Beta Blockers to Treat Mitral Regurgitation October 2007 September 2009
NCT02762331 Terminated Phase 1 High Dose Vitamin C in Cardiac Surgery Patients January 1, 2017 March 13, 2018
NCT00598936 Terminated A Prospective Study With a New Device for the Monitoring of Cerebral Oxygenation on Cardiac Surgery Patients November 2007 May 2009
NCT01283321 Terminated Phase 2 RiaSTAP vs. Conventional Transfusion in Patients Having Heart Valve Surgery January 2011 May 2013
NCT02478008 Terminated N/A A Clinical Study of the CardiAQ™ TMVI System (Transapical DS) June 2015 August 2015
NCT01812174 Terminated N/A On-X Heart Valve - 17mm Aortic and 23mm Mitral November 18, 2011 December 7, 2018
NCT01855737 Unknown status The Study of Warfarin Maintenance Dose in Chinese Patients June 2013 January 2014
NCT01000233 Unknown status Phase 2/Phase 3 Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications August 2009 October 2012
NCT01610141 Unknown status Phase 4 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients June 2012 June 2015
NCT02574650 Unknown status N/A Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Also Known as TriAlign™. November 2015 May 2019
NCT02650388 Unknown status Phase 4 Frailty and Cognitive Function Assessment of TAVI Patients November 2015 October 2018
NCT02710747 Unknown status Phase 4 The Pharmacogenetics of Optimal Warfarin Therapy in Chinese Patients After Heart Valve Replacement. January 2015 July 2016
NCT03012997 Unknown status N/A Effects of Hyperoxia on Open Heart Surgery December 2016 April 2017
NCT03225612 Unknown status N/A Safety and Performance of the Trialign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) May 22, 2017 November 2022
NCT00187304 Withdrawn Phase 4 ACTION - Anticoagulation Treatment Influence on Post-operative Patients September 2005
NCT02515539 Withdrawn N/A Early Feasibility Study of the CardiAQ™ TMVI System (Transfemoral and Transapical DS) August 2015 July 2021
NCT03928639 Withdrawn Structural Heart and Valve Network PROSPECTIVE Registry January 10, 2023 January 10, 2023
Disase is a (Disease Ontology)
DOID:114
Cross Reference ID (Disease Ontology)
MESH:D006349
Cross Reference ID (Disease Ontology)
MESH:D016127
Cross Reference ID (Disease Ontology)
NCI:C45525
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:368009
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:398995000
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0018824
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0079485
Exact Synonym (Disease Ontology)
Valvular heart disease