chr19:41330323:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr19:41,836,228-41,859,827 
hg38 chr19:41,330,323-41,353,922

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.165 squamous cell carcinoma Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacan... BeFree,CTD_human,GAD,LHGDN 24954139 Detail
0.165 squamous cell carcinoma For C/EBPβ, only the abundant full-length isoform (C/EBPβ-1, LAP*, 55 kD) was re... BeFree,CTD_human,GAD,LHGDN 25402211 Detail
0.165 squamous cell carcinoma We incubated the p16-positive CERV196 and p16-negative HNSCC22B SCC cell lines w... BeFree,CTD_human,GAD,LHGDN 25503133 Detail
0.004 Carcinoma, Transitional Cell Given that the tumor-promoting inflammation has been previously established in s... BeFree,LHGDN 24448750 Detail
0.120 carcinosarcoma NA CTD_human Detail
<0.001 Cardiomyopathy, Dilated NA BeFree Detail
0.014 Cardiovascular Diseases NA BeFree,GAD,LHGDN Detail
0.002 carotid stenosis NA GAD Detail
0.010 celiac disease NA BeFree,GAD,LHGDN Detail
0.120 Neoplastic Cell Transformation NA CTD_human Detail
0.002 cellulitis NA GAD Detail
0.002 intracranial aneurysm NA GAD Detail
0.001 cerebral infarction NA BeFree Detail
0.085 brain ischemia NA GAD,RGD Detail
0.002 Malignant tumor of cervix NA BeFree Detail
0.002 Uterine Cervical Incompetence NA GAD Detail
0.007 Uterine Cervical Neoplasm NA GAD Detail
0.005 Chlamydia Infections NA GAD Detail
<0.001 Primary biliary cirrhosis NA BeFree Detail
<0.001 cholera NA BeFree Detail
0.005 cholesteatoma NA LHGDN Detail
0.006 chondrosarcoma NA BeFree,LHGDN Detail
0.002 chorioamnionitis NA GAD Detail
<0.001 choriocarcinoma NA BeFree Detail
<0.001 Congenital chromosomal disease NA BeFree Detail
<0.001 Churg-Strauss syndrome NA BeFree Detail
0.005 Cicatrization NA GAD Detail
0.002 cleft lip NA GAD Detail
0.125 cleft palate NA CTD_human,GAD Detail
0.002 clonorchiasis NA GAD Detail
0.004 colitis NA BeFree,LHGDN Detail
0.016 ulcerative colitis NA BeFree,GAD,LHGDN Detail
0.006 Colonic Neoplasms NA BeFree,LHGDN Detail
0.002 Colonic Polyps NA GAD Detail
0.010 colorectal carcinoma CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated su... BeFree 25268580 Detail
0.010 colorectal carcinoma Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer... BeFree 25884904 Detail
0.155 Colorectal Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
0.002 common variable immunodeficiency NA GAD Detail
0.003 Connective Tissue Diseases NA BeFree,GAD Detail
0.003 Corneal Diseases NA LHGDN Detail
0.009 Hereditary corneal dystrophy NA GAD Detail
<0.001 corneal dystrophy NA BeFree Detail
0.001 Coronary Arteriosclerosis Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Gr... BeFree 25155040 Detail
0.008 Coronary heart disease Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Gr... BeFree,GAD 25155040 Detail
<0.001 Coughing NA BeFree Detail
0.006 Crohn Disease Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression ... BeFree,GAD 25740948 Detail
0.006 Crohn Disease TAK1 inhibition or silencing significantly reduced TGF-β1-stimulated collagen pr... BeFree,GAD 26185333 Detail
<0.001 adenoid cystic carcinoma The data indicate that the overexpression of survivin in AdCC is related to HIF-... BeFree 25485635 Detail
0.391 cystic fibrosis Therefore, we propose that TGF-β1-induced mucociliary dysfunction in CF airways ... BeFree,CLINVAR,CTD_human,GAD,LHGDN,ORPHANET 26338706 Detail
<0.001 Cytomegalovirus Infections NA BeFree Detail
0.003 Cessation of life NA LHGDN Detail
0.002 Hepatitis D Infection NA GAD Detail
0.008 Dementia, Vascular NA BeFree,GAD,LHGDN Detail
0.003 Mental Depression NA BeFree,GAD Detail
<0.001 depressive disorder NA BeFree Detail
0.006 Dermatitis, Atopic Tacrolimus (FK506) ointment has been reported to be effective for treating AD as... BeFree,GAD,LHGDN 23301526 Detail
<0.001 dermatomyositis NA BeFree Detail
0.003 scleroderma NA BeFree Detail
0.001 Diabetes NA BeFree Detail
0.002 diabetes mellitus NA BeFree Detail
0.200 Diabetes Mellitus, Experimental NA CTD_human,RGD Detail
0.023 Diabetes Mellitus, Insulin-Dependent Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in... BeFree,GAD,LHGDN 25931475 Detail
0.151 Diabetes Mellitus, Non-Insulin-Dependent Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with... BeFree,CTD_human,GAD,LHGDN 25871499 Detail
0.151 Diabetes Mellitus, Non-Insulin-Dependent Our findings suggest that TGF-β1 and IL-10 polymorphisms are involved in complic... BeFree,CTD_human,GAD,LHGDN 26064986 Detail
0.244 Diabetic Nephropathy In cultured podocytes, various cytokines related to diabetic nephropathy includi... BeFree,CTD_human,GAD,LHGDN,RGD 24670409 Detail
0.244 Diabetic Nephropathy Targeting cellular drivers and counter-regulators of hyperglycaemia- and transfo... BeFree,CTD_human,GAD,LHGDN,RGD 25085843 Detail
0.244 Diabetic Nephropathy This Review discusses current understanding of the function of miRNAs in CKD, fo... BeFree,CTD_human,GAD,LHGDN,RGD 25385286 Detail
0.244 Diabetic Nephropathy Transforming growth factor-beta1 (TGF-β1), a ubiquitously expressed pro-fibrotic... BeFree,CTD_human,GAD,LHGDN,RGD 25871499 Detail
0.200 Diabetic Neuropathies NA CTD_human,RGD Detail
0.003 diabetic retinopathy Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codo... BeFree,GAD 26064986 Detail
0.490 Camurati-Engelmann Syndrome We cautiously conclude that TGFβ1 inhibition with losartan deserves further eval... BeFree,CLINVAR,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25099136 Detail
<0.001 Down syndrome NA BeFree Detail
0.005 drug allergy NA GAD Detail
0.120 Dry Eye Syndromes NA CTD_human Detail
0.121 Muscular Dystrophy, Duchenne NA BeFree,CTD_human Detail
0.123 duodenal ulcer NA BeFree,CTD_human,LHGDN Detail
0.003 Dupuytren Contracture NA BeFree,GAD Detail
<0.001 Dwarfism NA BeFree Detail
<0.001 Dyspnea NA BeFree Detail
0.006 eclampsia The mechanisms may include the following pathways: [TGFB1 or TNFA]-[IL1B]-[pre-e... BeFree,GAD 25879409 Detail
0.006 eclampsia TGFB1 Functional Gene Polymorphisms (C-509T and T869C) in the Maternal Susceptib... BeFree,GAD 26173679 Detail
0.001 Eczema Tacrolimus (FK506) ointment has been reported to be effective for treating AD as... BeFree 23301526 Detail
0.003 Eisenmenger Complex NA LHGDN Detail
0.002 Pathological accumulation of air in tissues NA GAD Detail
0.081 Experimental Autoimmune Encephalomyelitis NA BeFree,RGD Detail
0.002 Endometrial Neoplasms NA GAD Detail
0.012 endometriosis In conclusion, the peritoneum, and in particular, the peritoneal mesothelium, is... BeFree,GAD,LHGDN 25207642 Detail
<0.001 Eosinophilia NA BeFree Detail
0.002 Equine Infectious Anemia NA GAD Detail
<0.001 erythema nodosum NA BeFree Detail
0.018 Esophageal Neoplasms NA BeFree,GAD,LHGDN Detail
<0.001 esophagitis NA BeFree Detail
<0.001 Exanthema NA BeFree Detail
<0.001 External exotoses NA BeFree Detail
<0.001 Eye Neoplasms NA BeFree Detail
<0.001 fasciitis NA BeFree Detail
0.008 Fatty Liver NA BeFree,GAD,LHGDN Detail
0.002 Fetal Diseases NA GAD Detail
0.002 Fetal Membranes, Premature Rupture NA GAD Detail
<0.001 fibrosarcoma NA BeFree Detail
0.186 Fibrosis NA CTD_human,GAD,LHGDN Detail
0.003 pathologic fistula NA BeFree,LHGDN Detail
0.003 Folic Acid Deficiency NA LHGDN Detail
0.002 food allergy NA GAD Detail
0.005 gallbladder neoplasm NA LHGDN Detail
0.006 gastritis FOXP3 mRNA levels were correlated positively with TGF-β1 and IL-10 mRNA levels i... BeFree,GAD 24121150 Detail
<0.001 Gastrointestinal Diseases NA BeFree Detail
<0.001 Giant Cell Tumors NA BeFree Detail
0.002 giardiasis NA GAD Detail
<0.001 Gingival Diseases NA BeFree Detail
0.002 Gingival Hyperplasia NA GAD Detail
0.003 glaucoma NA LHGDN Detail
0.005 Glaucoma, Open-Angle NA GAD Detail
0.002 glioblastoma NA BeFree Detail
0.291 asthma Proposed test statistics are applied to NHANES III data to test for associations... BeFree 19745160 Detail
0.090 obesity Proposed test statistics are applied to NHANES III data to test for associations... BeFree 19745160 Detail
0.011 Glioma Impact of TGF-β1 -509C/T and 869T/C polymorphisms on glioma risk and patient pro... BeFree,LHGDN 25813152 Detail
0.009 glomerulonephritis NA BeFree,GAD,LHGDN Detail
0.153 IgA glomerulonephritis The TGF-β1-509T/C-dominant model for the C allele was significantly associated w... BeFree,CTD_human,GAD,LHGDN 24271554 Detail
0.153 IgA glomerulonephritis This meta-analysis does not support the hypothesis that TGF-β1 gene-509C/T polym... BeFree,CTD_human,GAD,LHGDN 25112155 Detail
0.126 Focal glomerulosclerosis NA BeFree,CTD_human,GAD Detail
<0.001 goiter NA BeFree Detail
0.027 Graft-vs-Host Disease NA BeFree,GAD Detail
0.005 Graves Disease Arg25Pro (c.915G>C) polymorphism of transforming growth factor β1 gene increases... BeFree,GAD 24742542 Detail
0.005 Head and Neck Neoplasms NA GAD Detail
0.003 Heart block NA LHGDN Detail
<0.001 Heart Diseases Transforming growth factor-β(1) (TGF-β(1)) is an important regulator of fibrogen... BeFree 25789971 Detail
0.080 Cardiomegaly NA RGD Detail
0.005 Heart failure Up-regulation was evident for muscle LIM protein (Mlp), desmin, and heart failur... BeFree,GAD,LHGDN 25541130 Detail
<0.001 congestive heart failure Up-regulation was evident for muscle LIM protein (Mlp), desmin, and heart failur... BeFree 25541130 Detail
0.003 heart valve disease NA BeFree,GAD Detail
<0.001 hemangioma NA BeFree Detail
0.002 Hematological Disease NA GAD Detail
0.002 hemochromatosis NA GAD Detail
<0.001 Hemophilia A Plant-based oral tolerance to hemophilia therapy employs a complex immune regula... BeFree 25700434 Detail
0.005 Severe Dengue NA BeFree,GAD Detail
<0.001 hepatic veno-occlusive disease NA BeFree Detail
0.003 hepatitis High levels of periostin in patients with acute or chronic hepatitis correlated ... BeFree,LHGDN 25541330 Detail
<0.001 hepatitis A High levels of periostin in patients with acute or chronic hepatitis correlated ... BeFree 25541330 Detail
0.019 hepatitis B Association of serum IgG N-glycome and transforming growth factor-β1 with hepati... BeFree,GAD,LHGDN 25260899 Detail
0.019 hepatitis B The relationship between hepatitis B virus (HBV) load and levels of transforming... BeFree,GAD,LHGDN 25990938 Detail
0.124 Hepatitis, Chronic High levels of periostin in patients with acute or chronic hepatitis correlated ... BeFree,CTD_human,LHGDN 25541330 Detail
0.032 hepatitis C In this study, we confirmed that the TGF-β1 polymorphism 509 C>T is associated w... BeFree,GAD,LHGDN 25966218 Detail
0.032 hepatitis C HBV and hepatitis C virus (HCV) serological markers, sFas and TGF-β1 levels, and... BeFree,GAD,LHGDN 25990938 Detail
0.200 Diaphragmatic hernia NA CTD_human,RGD Detail
0.003 Herpes Simplex Infections NA BeFree,LHGDN Detail
<0.001 Hip Dislocation, Congenital Association of TGFB1 29C/T and IL6 -572G/C polymorphisms with developmental hip ... BeFree 25603974 Detail
0.009 HIV Infections NA BeFree,GAD,LHGDN Detail
0.019 breast carcinoma Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs19... BeFree 20640597 Detail
0.090 Malignant neoplasm of breast Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs19... BeFree 20640597 Detail
<0.001 Hodgkin Disease NA BeFree Detail
<0.001 Huntington disease NA BeFree Detail
0.003 hydronephrosis NA BeFree,LHGDN Detail
0.002 Hypercapnia NA GAD Detail
0.007 hyperglycemia Targeting cellular drivers and counter-regulators of hyperglycaemia- and transfo... BeFree,GAD,LHGDN 25085843 Detail
0.080 Hyperlipidemia NA RGD Detail
0.002 Hyperparathyroidism, Secondary NA GAD Detail
0.128 Hyperplasia NA CTD_human,GAD,LHGDN Detail
0.125 Hypersensitivity NA CTD_human,GAD Detail
0.002 Immediate hypersensitivity NA GAD Detail
0.240 Hypertensive disease Hypertension is associated with increased expression of FABP3, FAS, FN1, IL1R2, ... BeFree,CTD_human,GAD,LHGDN,RGD 23337395 Detail
0.240 Hypertensive disease Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Gr... BeFree,CTD_human,GAD,LHGDN,RGD 25155040 Detail
0.240 Hypertensive disease Hypertension was associated with the CC genotype and C allele for IL-10 -592C/A ... BeFree,CTD_human,GAD,LHGDN,RGD 26064986 Detail
0.002 Hypertension, Portal NA GAD Detail
0.005 pulmonary hypertension NA BeFree,GAD Detail
0.002 renal hypertension NA GAD Detail
<0.001 Hypodontia Association of MSX1 and TGF-β1 genetic polymorphisms with hypodontia: meta-analy... BeFree 25501212 Detail
0.003 Immune System Diseases NA BeFree,GAD Detail
0.002 Female infertility NA GAD Detail
0.002 male infertility NA GAD Detail
0.170 Inflammation NA CTD_human,GAD,LHGDN Detail
0.006 Inflammatory Bowel Diseases NA BeFree,GAD Detail
0.005 Insulin resistance NA GAD Detail
0.003 insulinoma NA LHGDN Detail
0.002 Intervertebral Disk Displacement NA GAD Detail
0.003 irritable bowel syndrome NA BeFree,GAD Detail
0.012 Keloid NA BeFree,GAD,LHGDN Detail
<0.001 keratoacanthoma Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacan... BeFree 24954139 Detail
<0.001 Keratoconjunctivitis, Vernal NA BeFree Detail
0.154 Kidney Diseases Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codo... BeFree,CTD_human,GAD 26064986 Detail
0.233 Kidney Failure, Chronic Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with... BeFree,CTD_human,GAD,LHGDN,RGD 25871499 Detail
0.233 Kidney Failure, Chronic Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in... BeFree,CTD_human,GAD,LHGDN,RGD 25931475 Detail
<0.001 Polycystic Kidney Diseases NA BeFree Detail
0.002 Premature Obstetric Labor NA GAD Detail
0.002 Laryngeal neoplasm NA GAD Detail
0.009 Fibroid Tumor NA BeFree,LHGDN Detail
0.003 leishmaniasis NA LHGDN Detail
<0.001 Leishmaniasis, Cutaneous NA BeFree Detail
<0.001 Leishmaniasis, Visceral NA BeFree Detail
0.002 leprosy NA GAD Detail
0.002 leptospirosis NA GAD Detail
0.007 leukemia NA BeFree,GAD Detail
0.006 chronic lymphocytic leukemia NA BeFree,LHGDN Detail
0.004 Acute Erythroblastic Leukemia NA BeFree,LHGDN Detail
0.003 hairy cell leukemia NA LHGDN Detail
<0.001 Acute Megakaryocytic Leukemias NA BeFree Detail
0.004 Leukemia, Myelocytic, Acute NA BeFree,LHGDN Detail
0.002 Myeloid Leukemia, Chronic We propose that this mechanism is activated by a ligand-receptor interaction bet... BeFree 25644060 Detail
<0.001 Leukemia, Myeloid, Chronic-Phase NA BeFree Detail
<0.001 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma NA BeFree Detail
<0.001 acute promyelocytic leukemia NA BeFree Detail
<0.001 Leukemia, T-Cell Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cel... BeFree 25358858 Detail
0.004 Adult T-Cell Lymphoma/Leukemia Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cel... BeFree,LHGDN 25358858 Detail
0.162 liver cirrhosis The aim of this study was to investigate the clinical significance of serum TGF-... BeFree,CTD_human,GAD,LHGDN 25475758 Detail
0.125 Liver Cirrhosis, Alcoholic NA BeFree,CTD_human,GAD Detail
0.200 Liver Cirrhosis, Experimental NA CTD_human,RGD Detail
0.009 Liver diseases NA BeFree,GAD,LHGDN Detail
0.008 Alcoholic Liver Diseases NA BeFree,GAD,LHGDN Detail
0.016 Liver neoplasms NA BeFree,GAD,LHGDN Detail
0.002 Low Back Pain NA GAD Detail
0.209 Lung diseases NA BeFree,CTD_human,GAD,LHGDN,RGD Detail
0.244 Chronic Obstructive Airway Disease Long-term effects of three Tiao-Bu Fei-Shen therapies on NF-κB/TGF-β1/smad2 sign... BeFree,CTD_human,GAD,LHGDN,RGD 24766819 Detail
0.136 Lung Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
0.026 Lupus Erythematosus, Systemic Single nucleotide polymorphism T869C of transforming growth factor-beta 1 gene a... BeFree,GAD,LHGDN 25812349 Detail
0.006 lupus nephritis Renal gene expression levels of transforming growth factor β-1 (TGFB1), and coll... BeFree,GAD 25724035 Detail
0.006 lupus nephritis Single nucleotide polymorphism T869C of transforming growth factor-beta 1 gene a... BeFree,GAD 25812349 Detail
0.003 Lyme disease NA LHGDN Detail
0.005 Lymphatic Metastasis NA GAD Detail
0.002 lymphoma NA BeFree Detail
<0.001 Lymphoma, Follicular NA BeFree Detail
0.007 Lymphoma, Non-Hodgkin NA GAD,LHGDN Detail
0.005 Lymphoproliferative Disorders NA GAD,LHGDN Detail
0.001 malaria NA BeFree Detail
0.014 Malignant neoplasm of stomach The HER-2 positive SGC-7901 secreted more transforming growth factor beta 1 (TGF... BeFree,GAD 25613482 Detail
0.009 Animal Mammary Neoplasms NA GAD Detail
0.004 Marfan syndrome In contrast to specific clinical features of MFS, FBN1 in-frame mutations (P = 0... BeFree,LHGDN 25113270 Detail
0.010 melanoma The expression of PRRs (Toll-like receptors and melanoma differentiation-associa... BeFree,GAD,LHGDN 26047816 Detail
0.006 meningioma NA BeFree,GAD,LHGDN Detail
<0.001 meningitis NA BeFree Detail
0.002 Mesothelioma NA GAD Detail
<0.001 Metabolic Diseases NA BeFree Detail
<0.001 Diseases of mitral valve In addition to oligodontia and short stature, both sisters have mitral valve pro... BeFree 25899461 Detail
0.002 Mouth Neoplasms NA GAD Detail
0.001 Moyamoya disease NA BeFree Detail
0.005 Mucocutaneous Lymph Node Syndrome NA GAD,LHGDN Detail
0.005 multiple myeloma NA LHGDN Detail
0.020 multiple sclerosis NA BeFree,GAD,LHGDN Detail
0.120 myopathy NA CTD_human Detail
0.002 Musculoskeletal Diseases NA GAD Detail
0.003 myasthenia gravis NA BeFree,LHGDN Detail
<0.001 Mycoplasma Infections NA BeFree Detail
<0.001 mycosis fungoides Transforming growth factor-β1 gene polymorphism in mycosis fungoides. BeFree 25156636 Detail
0.001 myelofibrosis NA BeFree Detail
0.138 myocardial infarction NA BeFree,CTD_human,GAD,LHGDN Detail
0.007 myopia NA BeFree,GAD Detail
<0.001 myositis NA BeFree Detail
0.011 Nasal Polyps NA BeFree,LHGDN Detail
0.005 Nasopharyngeal Neoplasms NA GAD Detail
<0.001 Neonatal hepatitis NA BeFree Detail
0.122 Neoplasm Invasiveness NA CTD_human,GAD Detail
0.147 Neoplasm Metastasis Transforming growth factor‑β1 (TGF‑β1) is involved in the migration and metastas... BeFree,CTD_human,LHGDN 25017509 Detail
0.147 Neoplasm Metastasis Furthermore, the enrichment of LAP⁺ Treg population in peripheral blood mononucl... BeFree,CTD_human,LHGDN 25268580 Detail
0.147 Neoplasm Metastasis These data suggest that a metabolic transition that suppresses lipogenesis and f... BeFree,CTD_human,LHGDN 25284588 Detail
0.147 Neoplasm Metastasis The processes of EMT and metastasis are highly regulated by a double-negative fe... BeFree,CTD_human,LHGDN 25422078 Detail
0.147 Neoplasm Metastasis We conclude that tumor-derived OPN engenders MSC-to-CAF transformation in the mi... BeFree,CTD_human,LHGDN 25531323 Detail
0.147 Neoplasm Metastasis TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esopha... BeFree,CTD_human,LHGDN 25544767 Detail
0.147 Neoplasm Metastasis However, the underlying mechanism of TGF-β1-mediated metastasis remains unclear. BeFree,CTD_human,LHGDN 25562163 Detail
0.147 Neoplasm Metastasis The morbidity and metastasis of osteosarcoma are relevant to TGF-β1 gene 29 T > ... BeFree,CTD_human,LHGDN 25663491 Detail
0.147 Neoplasm Metastasis IGF-IR and VEGF-A overexpression was observed to be correlated with TGF-β1 expre... BeFree,CTD_human,LHGDN 25824321 Detail
0.147 Neoplasm Metastasis Our new findings provided evidence that, resveratrol could inhibit EMT in CRC th... BeFree,CTD_human,LHGDN 25884904 Detail
0.147 Neoplasm Metastasis Overexpression of EGR 1 gene with EGR 1 vector could decrease tumor cell migrati... BeFree,CTD_human,LHGDN 25987100 Detail
0.005 Neoplasm Recurrence, Local NA GAD Detail
0.003 nephritis NA BeFree,GAD Detail
<0.001 nephroblastoma NA BeFree Detail
0.128 nephrotic syndrome NA BeFree,CTD_human,GAD,LHGDN Detail
0.036 Hepatitis C, Chronic The aim of this work was to establish an association between the single-nucleoti... BeFree 23941979 Detail
0.002 neuroblastoma NA BeFree Detail
<0.001 acoustic neuroma The objective of the present study was to investigate the expression level and t... BeFree 25738867 Detail
0.003 neutropenia NA LHGDN Detail
0.003 Thyroid Nodule Elevated thyroid nodule risks were associated with the minor alleles of RET S836... BeFree 19138047 Detail
<0.001 Nodule NA BeFree Detail
<0.001 Nocturia NA BeFree Detail
0.090 obesity NA BeFree,GAD,RGD Detail
0.002 Obesity, Morbid NA GAD Detail
0.126 oral submucous fibrosis NA BeFree,CTD_human,GAD Detail
0.002 Oropharyngeal Neoplasms NA GAD Detail
0.011 Degenerative polyarthritis These results suggest that the Tgf-β1 canonical signaling was activated to induc... BeFree,GAD,LHGDN 24135912 Detail
0.011 Degenerative polyarthritis Murine and human chondrocyte cell lines, primary bovine and human chondrocytes, ... BeFree,GAD,LHGDN 25529198 Detail
0.011 Degenerative polyarthritis To determine the effects of Bushenhuoxue formula (BHF) on interleukin-1 beta (IL... BeFree,GAD,LHGDN 25975052 Detail
<0.001 Osteoarthritis of hip Transforming growth factor-β1 (TGF-beta1) and interleukin-6 (IL-6) are included ... BeFree 25603974 Detail
<0.001 osteomalacia NA BeFree Detail
0.126 Osteoporosis, Postmenopausal The transforming growth factor-β1 (TGF-β1) gene polymorphisms (TGF-β1 T869C and ... BeFree,CTD_human,GAD 25634187 Detail
0.126 Osteoporosis, Postmenopausal QEF-treated serum, particularly that containing moderate and high concentrations... BeFree,CTD_human,GAD 26205885 Detail
0.002 osteosarcoma TGF-β1 promotes osteosarcoma cell migration and invasion through the miR-143-ver... BeFree 25562163 Detail
0.002 osteosarcoma Correlation between TGF-β1 gene 29 T > C single nucleotide polymorphism and clin... BeFree 25663491 Detail
<0.001 osteosclerosis NA BeFree Detail
0.015 otosclerosis NA BeFree,GAD,LHGDN Detail
0.004 ovarian carcinoma Furthermore, our results also provided evidence concerning the role of inflammat... BeFree 24931361 Detail
0.004 ovarian carcinoma Among numerous EMT-associated transcripts, Smad7 is considered to be an inhibito... BeFree 25333457 Detail
<0.001 Ovarian Diseases NA BeFree Detail
0.002 Pain, Postoperative NA GAD Detail
0.131 Pancreatic Neoplasm NA BeFree,CTD_human,GAD,LHGDN Detail
0.005 pancreatitis NA BeFree,GAD,LHGDN Detail
0.121 papilloma NA BeFree,CTD_human Detail
0.003 tropical spastic paraparesis NA LHGDN Detail
0.002 Paraproteinemias NA GAD Detail
0.002 Pelvic Pain NA GAD Detail
0.006 Pemphigoid, Benign Mucous Membrane NA BeFree,LHGDN Detail
0.007 pemphigus NA GAD Detail
0.002 pemphigus vulgaris NA GAD Detail
0.126 Peyronie Disease Transforming growth factor-β1 (TGF-β1) has been identified as one of the most im... BeFree,CTD_human,GAD,LHGDN 25532569 Detail
0.005 Peptic Ulcer NA GAD,LHGDN Detail
0.002 polyarteritis nodosa NA GAD Detail
0.003 Periodontal Diseases NA BeFree,GAD Detail
0.015 periodontitis NA BeFree,GAD,LHGDN Detail
0.002 Periodontitis, Juvenile NA GAD Detail
<0.001 peritonitis NA BeFree Detail
0.002 Pharyngeal Neoplasms NA GAD Detail
<0.001 pituitary adenoma NA BeFree Detail
<0.001 Pituitary Diseases NA BeFree Detail
<0.001 Pituitary Neoplasms NA BeFree Detail
0.005 pneumoconiosis NA GAD Detail
0.122 pneumonia NA BeFree,CTD_human Detail
0.003 polycystic ovary syndrome Our results provide additional evidence that TGFB lays a key role in the early p... BeFree,GAD 24874013 Detail
0.003 polycystic ovary syndrome Polymorphisms and haplotypes of the TGF-β1 gene are associated with risk of poly... BeFree,GAD 25594618 Detail
<0.001 Adenomatous Polyposis Coli NA BeFree Detail
<0.001 polyps NA BeFree Detail
0.007 Postoperative Complications NA GAD Detail
0.015 pre-eclampsia NA GAD,LHGDN Detail
0.006 Precancerous Conditions NA BeFree,GAD Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
0.002 Pregnancy Complications, Infectious NA GAD Detail
0.007 Preleukemia NA BeFree,GAD Detail
<0.001 priapism NA BeFree Detail
<0.001 Prostatic Diseases NA BeFree Detail
0.150 Prostatic Neoplasms Effects of TGFβ1 on control prostate cancer PC3 and DU145 cells and those with I... BeFree,CTD_human,LHGDN 25746720 Detail
0.003 prostatitis NA BeFree,GAD Detail
0.120 proteinuria NA CTD_human Detail
0.002 Pseudomonas Infections NA GAD Detail
0.004 psoriasis Transforming growth factor-β1 mediates psoriasis-like lesions via a Smad3-depend... BeFree,GAD 25132073 Detail
<0.001 Psychotic Disorders NA BeFree Detail
0.002 Delayed puberty NA GAD Detail
0.002 Precocious Puberty NA GAD Detail
0.240 Hypertensive disease In some, but not all, studies, IL6 -174G/C (rs1800795) and TGFB1 869T/C (rs19820... BeFree 19106168 Detail
0.123 pulmonary emphysema NA BeFree,CTD_human,GAD Detail
0.214 pulmonary fibrosis At day 7, lung tissue acquired significant amounts of mtDNA deletions, translati... BeFree,CTD_human,GAD,LHGDN,RGD 24939573 Detail
0.214 pulmonary fibrosis miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis. BeFree,CTD_human,GAD,LHGDN,RGD 24953558 Detail
0.214 pulmonary fibrosis In vitro, fibroblast growth factor (FGF) 2 promotes myofibroblast differentiatio... BeFree,CTD_human,GAD,LHGDN,RGD 24988442 Detail
0.214 pulmonary fibrosis Particular attention has been paid to the understanding of the role of these pro... BeFree,CTD_human,GAD,LHGDN,RGD 25178906 Detail
0.214 pulmonary fibrosis In this study, the effects of PA on the transforming growth factor-β1 (TGF-β1)-m... BeFree,CTD_human,GAD,LHGDN,RGD 25582705 Detail
0.214 pulmonary fibrosis Pulmonary fibrosis is an epithelial-mesenchymal disorder in which TGF-β1 plays a... BeFree,CTD_human,GAD,LHGDN,RGD 25584011 Detail
0.214 pulmonary fibrosis In the present study, we found that miR-153 expression was dysregulated in the l... BeFree,CTD_human,GAD,LHGDN,RGD 26216407 Detail
0.002 Henoch-Schoenlein purpura NA GAD Detail
0.002 Q fever NA GAD Detail
0.002 reflex sympathetic dystrophy NA GAD Detail
0.005 kidney failure Both high expression of TGFB1 or COL1 tended to predict renal failure by univari... BeFree,GAD 25724035 Detail
0.005 kidney failure Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in... BeFree,GAD 25931475 Detail
0.002 Reperfusion Injury NA GAD Detail
0.003 Respiratory Distress Syndrome, Adult NA BeFree,LHGDN Detail
0.002 Respiratory Hypersensitivity NA GAD Detail
0.002 Respiratory Syncytial Virus Infections NA GAD Detail
0.002 retinoblastoma NA BeFree Detail
0.002 retinopathy of prematurity NA GAD Detail
0.001 rhabdomyosarcoma NA BeFree Detail
0.003 rheumatic fever NA LHGDN Detail
0.010 rheumatic heart disease NA GAD,LHGDN Detail
0.005 Rhinitis, Allergic, Perennial NA GAD Detail
0.134 sarcoidosis We evaluated gene expression of TGF-β1, SMAD2, 3 and 7 in bronchoalveolar lavage... BeFree,CTD_human,GAD,LHGDN 25753554 Detail
<0.001 Burn scar NA BeFree Detail
<0.001 schistosomiasis Immunohistochemistry (IHC) analyses displayed that the expression of Hsp47, TGF-... BeFree 25111595 Detail
<0.001 Schistosomiasis japonica NA BeFree Detail
0.003 Schistosomiasis mansoni NA LHGDN Detail
0.003 localized scleroderma NA BeFree,LHGDN Detail
0.020 systemic scleroderma c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemi... BeFree,GAD 25876876 Detail
0.003 Scoliosis, unspecified NA LHGDN Detail
<0.001 Septicemia NA BeFree Detail
<0.001 organic sexual dysfunction NA BeFree Detail
<0.001 Sezary syndrome NA BeFree Detail
0.003 silicosis NA BeFree,GAD Detail
0.002 sinusitis NA GAD Detail
0.003 Dermatologic disorders NA BeFree,GAD Detail
<0.001 Skin lesion NA BeFree Detail
0.120 Skin Neoplasms NA BeFree,CTD_human Detail
0.002 Skin Ulcer NA GAD Detail
0.002 Spinal Osteophytosis NA GAD Detail
0.008 ankylosing spondylitis NA BeFree,GAD Detail
0.030 Stomach Neoplasms NA BeFree,GAD,LHGDN Detail
0.002 aphthous stomatitis NA GAD Detail
0.136 Cerebrovascular accident NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 Giant Cell Arteritis NA BeFree Detail
<0.001 Temporomandibular Joint Dysfunction Syndrome NA BeFree Detail
0.002 Thoracic Neoplasms NA GAD Detail
0.121 Thrombocythemia, Essential NA BeFree,CTD_human Detail
0.003 thrombocytopenia NA LHGDN Detail
0.005 thrombosis NA GAD Detail
<0.001 thymoma NA BeFree Detail
0.003 Thyroid Diseases NA LHGDN Detail
0.003 Thyroid Neoplasm NA BeFree,LHGDN Detail
0.003 Thyroid Nodule A significantly greater expression of TGF-β1 (p < 0.0001) was detected in the gr... BeFree,LHGDN 25927212 Detail
0.002 Tobacco use disorder NA GAD Detail
<0.001 Tooth Crowding NA BeFree Detail
0.002 Gilles de la Tourette syndrome NA GAD Detail
0.005 tracheal stenosis NA GAD,LHGDN Detail
0.002 trachoma NA GAD Detail
0.003 Chagas disease NA BeFree,GAD Detail
0.014 tuberculosis NA BeFree,GAD,LHGDN Detail
0.003 pleural tuberculosis NA LHGDN Detail
0.010 Tuberculosis, Pulmonary NA BeFree,GAD,LHGDN Detail
0.001 Squamous cell carcinoma of the head and neck We have recently shown that the single nucleotide polymorphism (SNP) rs1982073 o... BeFree 20308003 Detail
0.122 pneumonia Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is assoc... BeFree 19380441 Detail
0.020 Malignant neoplasm of lung [Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is asso... GAD 19380441 Detail
0.009 Non-small cell lung carcinoma Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is assoc... BeFree 19380441 Detail
<0.001 Pneumonitis Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is assoc... BeFree 19380441 Detail
0.120 uremia NA CTD_human Detail
0.121 ureteral obstruction In the UUO model, administration of apelin significantly attenuated renal inters... BeFree,CTD_human 25164121 Detail
0.080 urethral obstruction NA RGD Detail
0.003 Urinary Incontinence NA LHGDN Detail
0.003 urinary tract infection NA BeFree,LHGDN Detail
0.002 Urogenital Abnormalities NA GAD Detail
0.125 urticaria NA CTD_human,GAD Detail
<0.001 Uterine Fibroids NA BeFree Detail
<0.001 Varicose Ulcer NA BeFree Detail
0.003 Vascular Diseases NA BeFree,LHGDN Detail
0.018 Vesico-Ureteral Reflux NA BeFree,GAD,LHGDN Detail
<0.001 viral hepatitis NA BeFree Detail
0.002 Viremia NA GAD Detail
<0.001 Virus Diseases NA BeFree Detail
0.080 Wallerian Degeneration NA RGD Detail
<0.001 Wheezing NA BeFree Detail
0.006 Fibromatosis, Aggressive NA BeFree,LHGDN Detail
0.003 epidermolysis bullosa acquisita NA LHGDN Detail
0.012 Helicobacter Infections NA GAD Detail
0.006 B-Cell Lymphomas NA BeFree,GAD,LHGDN Detail
<0.001 T-Cell Lymphoma NA BeFree Detail
<0.001 Lymphoma, T-Cell, Cutaneous These findings provide the first insights into the BZ-regulated TGF-β1 and IL-10... BeFree 25681335 Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
0.003 Foot Ulcer NA LHGDN Detail
0.005 Bronchial Hyperreactivity NA GAD Detail
<0.001 Central Nervous System Neoplasms NA BeFree Detail
<0.001 eosinophilia-myalgia syndrome NA BeFree Detail
0.003 gestational diabetes NA LHGDN Detail
0.002 Ovarian Failure, Premature NA GAD Detail
0.002 cerebral amyloid angiopathy NA GAD Detail
0.002 erythema infectiosum NA GAD Detail
0.001 essential hypertension Recent advances require further research of TGF-β1 receptor in EH. BeFree 24687999 Detail
0.002 Liver failure NA GAD Detail
<0.001 polymyositis NA BeFree Detail
<0.001 Chronic gastritis Our results show that IL-17A G197A, IL-17F A7488G andIL23R +2199A/C polymorphism... BeFree 26151690 Detail
<0.001 Depressive Symptoms NA BeFree Detail
0.001 cataract NA BeFree Detail
<0.001 benign neoplasm NA BeFree Detail
<0.001 Rous Sarcoma NA BeFree Detail
0.010 Pancreatitis, Chronic NA BeFree,GAD Detail
<0.001 congenital heart block NA BeFree Detail
<0.001 Bicuspid aortic valve Similarly, tsTGF-β1 levels were elevated in MFS (P = 0.003) and in BAVD (P = 0.0... BeFree 25113270 Detail
<0.001 Bicuspid aortic valve Confocal microscopy analysis showed a higher colocalization of latency associate... BeFree 25745062 Detail
0.005 Epstein-Barr Virus Infections NA GAD Detail
0.009 Left Ventricular Hypertrophy NA GAD Detail
<0.001 Spontaneous pneumothorax NA BeFree Detail
0.001 Small cell carcinoma of lung Here, we examined how TGF-β activates Src in H358 cells, a small cell lung carci... BeFree 25585026 Detail
0.123 Migraine Disorders To our knowledge, this is the first report dealing with the relationship between... BeFree,GAD,GWASCAT 24619148 Detail
<0.001 Atrophic condition of skin NA BeFree Detail
0.012 Premature Birth NA GAD Detail
0.008 renal fibrosis BMP-7 has a protective role against TGF-β1 in kidney fibrosis, whereas CTGF enha... BeFree 25176603 Detail
0.008 renal fibrosis Furthermore, increased expression of nuclear peroxisome proliferator-activated r... BeFree 25343824 Detail
0.008 renal fibrosis Epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 is one of well-reco... BeFree 25433496 Detail
0.008 renal fibrosis Transforming growth factor beta-1 (TGF-β1) is a cytokine with an important role ... BeFree 25439793 Detail
0.008 renal fibrosis Involvement of tumor suppressor ataxia telangiectasia mutated (ATM) in the TGF-β... BeFree 25480384 Detail
0.008 renal fibrosis M2 macrophages released high levels TGFβ1 to suppress BMP7 to enhance EMT-induce... BeFree 25662173 Detail
<0.001 Myocardial Ischemia NA BeFree Detail
0.002 Adenocarcinoma of lung (disorder) TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung aden... BeFree 25928368 Detail
<0.001 esophageal carcinoma TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esopha... BeFree 25544767 Detail
<0.001 Idiopathic pulmonary hypertension NA BeFree Detail
<0.001 Hodgkin's disease, nodular sclerosis (clinical) NA BeFree Detail
0.001 Malignant neoplasm of mouth TAZ promoted epithelial-to-mesenchymal transition (EMT) and also was involved in... BeFree 25704916 Detail
0.001 Malignant neoplasm of mouth TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer... BeFree 25744234 Detail
0.002 Malignant neoplasm of testis NA GAD Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 Secondary malignant neoplasm of skin NA BeFree Detail
<0.001 Secondary malignant neoplasm of bone HGF and TGFβ1 of bone-metastasis microenvironment acted co-ordinately, influenci... BeFree 26041563 Detail
<0.001 migraine with aura NA BeFree Detail
0.007 Myopia, Degenerative NA GAD Detail
<0.001 acute myocardial infarction NA BeFree Detail
<0.001 allergic asthma NA BeFree Detail
<0.001 Peritoneal adhesion NA BeFree Detail
<0.001 endometriosis of ovary Pathway analysis of the proteome measurements revealed a potential role for Tran... BeFree 25099244 Detail
0.120 Intervertebral Disc Degeneration NA BeFree,CTD_human Detail
<0.001 adrenoleukodystrophy NA BeFree Detail
<0.001 Androgenetic Alopecia NA BeFree Detail
<0.001 Immunoglobulin A deficiency (disorder) NA BeFree Detail
0.080 Right Ventricular Hypertrophy NA BeFree,RGD Detail
0.006 Cicatrix, Hypertrophic NA BeFree,GAD,LHGDN Detail
0.005 Aortic Aneurysm, Abdominal NA GAD Detail
<0.001 Aortic Aneurysm, Thoracic NA BeFree Detail
0.002 Glomerulosclerosis (disorder) NA BeFree Detail
0.007 Tumor Progression To date, no data have been reported concerning the influence of PTEN/PI3K signal... BeFree 25175594 Detail
0.003 Lung Diseases, Interstitial NA BeFree,GAD Detail
0.082 Radiation Pneumonitis NA GAD,RGD Detail
0.002 Lichen Planus, Oral NA GAD Detail
<0.001 Idiopathic hypereosinophilic syndrome NA BeFree Detail
0.003 Diabetic Foot NA LHGDN Detail
0.002 Ossification of Posterior Longitudinal Ligament NA GAD Detail
0.002 exfoliation syndrome NA GAD Detail
<0.001 Giant Cell Tumor of Bone NA BeFree Detail
<0.001 embryonal carcinoma NA BeFree Detail
0.005 Adenomatous Polyps NA GAD,LHGDN Detail
<0.001 Follicular thyroid carcinoma NA BeFree Detail
<0.001 Carcinoma, Endometrioid NA BeFree Detail
0.002 Carcinoma, Lobular NA GAD Detail
0.081 cholangiocarcinoma The molecular and cellular functions predicted for these CCA specific genes acco... BeFree,RGD 24935374 Detail
0.003 Cervical Intraepithelial Neoplasia NA BeFree,GAD Detail
<0.001 ganglioneuroblastoma NA BeFree Detail
<0.001 uveal melanoma NA BeFree Detail
0.001 Lip and oral cavity carcinoma TAZ promoted epithelial-to-mesenchymal transition (EMT) and also was involved in... BeFree 25704916 Detail
0.001 Lip and oral cavity carcinoma TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer... BeFree 25744234 Detail
<0.001 Chronic berylliosis NA BeFree Detail
<0.001 Adult type dermatomyositis NA BeFree Detail
0.002 Lytic lesion NA GAD Detail
0.002 alpha 1-antitrypsin deficiency NA GAD Detail
<0.001 chronic cystitis NA BeFree Detail
<0.001 Fibrillation Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollag... BeFree 25422138 Detail
<0.001 Sensory denervation disorder NA BeFree Detail
<0.001 Subcapsular cataract NA BeFree Detail
<0.001 granulomatous hepatitis NA BeFree Detail
<0.001 Malignant neoplasm of female breast NA BeFree Detail
<0.001 gallbladder carcinoma NA BeFree Detail
0.007 pancreatic carcinoma Surprisal analysis of mRNA time course data from lung and pancreatic cancer cell... BeFree 25157127 Detail
0.007 pancreatic carcinoma Overexpression of TGFβ1 enhanced the invasiveness of PCC cells, while inhibition... BeFree 25409617 Detail
0.007 pancreatic carcinoma Silencing of Gli1 alone without external stimulus had no effect on EMT but inhib... BeFree 25979438 Detail
0.001 Renal interstitial fibrosis Protein expressions of TGF-β1, Col-IV, and FN, and RIF index or cell apoptosis i... BeFree 24471428 Detail
0.002 Small for gestational age (disorder) NA GAD Detail
<0.001 Radiation esophagitis NA BeFree Detail
0.001 Papillary thyroid carcinoma In this study, we demonstrated that expression of TGF-β1 but not TGF-β2 is signi... BeFree 25927212 Detail
0.007 Fibrosis, Liver TRPV4 mRNA and protein were measured by RT-PCR and Western blot in patients and ... BeFree 25013893 Detail
0.007 Fibrosis, Liver Fibrogenic cytokines, such as transforming growth factor-beta 1 play a central r... BeFree 25030555 Detail
0.007 Fibrosis, Liver Expression of heat shock protein 47, transforming growth factor-beta 1, and conn... BeFree 25111595 Detail
0.007 Fibrosis, Liver Our results showed that miR-181b expression was increased much higher than miR-1... BeFree 25148875 Detail
0.007 Fibrosis, Liver Human and murine primary liver fibrosis-associated cells were isolated and treat... BeFree 25155445 Detail
0.007 Fibrosis, Liver Smad2 protects against TGF-β1/Smad3-mediated collagen synthesis in human hepatic... BeFree 25351340 Detail
0.007 Fibrosis, Liver Further, miR-126 promoted TNF-a-induced TGF-β1 and collagen I mRNA expression in... BeFree 25974152 Detail
0.001 Interstitial fibrosis NA BeFree Detail
0.122 Hepatitis, Autoimmune NA CTD_human,GAD Detail
<0.001 Calcium Pyrophosphate Dihydrate Deposition NA BeFree Detail
0.083 Erectile dysfunction NA BeFree,LHGDN,RGD Detail
0.120 Acute Lung Injury NA CTD_human Detail
<0.001 Mucosa-Associated Lymphoid Tissue Lymphoma NA BeFree Detail
0.002 Ventricular Dysfunction, Left NA GAD Detail
0.080 Hyperoxia NA RGD Detail
0.003 Proliferative vitreoretinopathy NA BeFree,LHGDN Detail
0.120 Sepsis NA BeFree,CTD_human Detail
<0.001 Carcinoma, Lewis Lung NA BeFree Detail
<0.001 Malignant Meningioma NA BeFree Detail
0.003 Carcinoma, Small Cell NA LHGDN Detail
<0.001 Psoriasis vulgaris NA BeFree Detail
<0.001 Epithelial hyperplasia of skin NA BeFree Detail
<0.001 disseminated eosinophilic collagen disease NA BeFree Detail
<0.001 Generalized morphea NA BeFree Detail
<0.001 Childhood asthma NA BeFree Detail
<0.001 Thickening of pleura NA BeFree Detail
<0.001 Rheumatic disease of heart valve NA BeFree Detail
<0.001 Rheumatic disease of mitral valve In addition to oligodontia and short stature, both sisters have mitral valve pro... BeFree 25899461 Detail
<0.001 Secondary pulmonary hypertension NA BeFree Detail
<0.001 Dilatation of aorta NA BeFree Detail
0.120 acromicric dysplasia NA CTD_human Detail
<0.001 Turcot syndrome (disorder) NA BeFree Detail
0.010 Chronic Periodontitis A total of 84 patients with generalized aggressive periodontitis (GAP,n:29), gen... BeFree,LHGDN 25638399 Detail
<0.001 Gastric dysplasia In the present study, we compared the time course of messenger RNA (mRNA) expres... BeFree 25784376 Detail
<0.001 Bile duct proliferation NA BeFree Detail
<0.001 Pancreatitis, Acute Necrotizing NA BeFree Detail
<0.001 Cutis Laxa, Autosomal Recessive, Type I NA BeFree Detail
<0.001 Renal glomerular disease NA BeFree Detail
<0.001 Spastic syndrome NA BeFree Detail
0.001 Severe myopia NA BeFree Detail
<0.001 Acute otitis media NA BeFree Detail
0.003 Disease due to Parvoviridae NA BeFree,GAD Detail
<0.001 Chronic viral hepatitis NA BeFree Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
0.002 Squamous cell carcinoma of esophagus Transforming growth factor-β1-induced epithelial-mesenchymal transition in human... BeFree 25175594 Detail
0.002 Squamous cell carcinoma of esophagus Taken together, our results suggest a novel and critical role of TIP30 involved ... BeFree 25544767 Detail
<0.001 childhood acute promyelocytic leukemia (M3) NA BeFree Detail
<0.001 Transitional cell carcinoma of bladder NA BeFree Detail
<0.001 bladder squamous cell carcinoma Given that the tumor-promoting inflammation has been previously established in s... BeFree 24448750 Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma NA BeFree Detail
<0.001 stage, bladder cancer NA BeFree Detail
<0.001 stage, prostate cancer NA BeFree Detail
<0.001 uterine carcinosarcoma NA BeFree Detail
<0.001 diffuse astrocytoma We focused on TGFB1I1 (TGF-β1 induced transcript 1) whose expression correlation... BeFree 25333259 Detail
<0.001 Very Low Birth Weight NA BeFree Detail
<0.001 Condyloma NA BeFree Detail
0.009 cervix carcinoma NA BeFree,GAD Detail
<0.001 Healing ulcer NA BeFree Detail
<0.001 Senile Plaques Following an oral treatment of 10 days, Icariin significantly attenuated Aβ depo... BeFree 25101849 Detail
<0.001 Segmental glomerulosclerosis NA BeFree Detail
0.005 Atrophic NA GAD,LHGDN Detail
<0.001 Carcinoid tumor no ICD-O subtype NA BeFree Detail
<0.001 epithelioid cell melanoma NA BeFree Detail
0.001 Adenocarcinoma of colon Validation of COL11A1/procollagen 11A1 expression in TGF-β1-activated immortalis... BeFree 25417197 Detail
<0.001 Common Migraine Codon 10 C/T genotypic and C10 C allelic frequency of TGF-β1 polymorphisms were ... BeFree 24619148 Detail
0.003 Thyroid associated opthalmopathies NA BeFree,GAD Detail
<0.001 Glaucoma, Primary Open Angle NA BeFree Detail
<0.001 Stable angina NA BeFree Detail
<0.001 Lone atrial fibrillation A functional polymorphism C-509T in TGFβ-1 promoter contributes to susceptibilit... BeFree 25402477 Detail
<0.001 Sporadic primary pulmonary hypertension NA BeFree Detail
<0.001 Familial primary pulmonary hypertension NA BeFree Detail
<0.001 eosinophilic esophagitis NA BeFree Detail
<0.001 Chronic liver disease NA BeFree Detail
<0.001 Maturity onset diabetes mellitus in young NA BeFree Detail
0.002 juvenile polyposis syndrome NA GAD Detail
0.003 Malignant neoplasm of liver NA BeFree,GAD Detail
<0.001 Benign neoplasm of breast NA BeFree Detail
<0.001 chronic eosinophilic leukemia NA BeFree Detail
0.006 Malignant neoplasm of pancreas Surprisal analysis of mRNA time course data from lung and pancreatic cancer cell... BeFree 25157127 Detail
0.006 Malignant neoplasm of pancreas Silencing of Gli1 alone without external stimulus had no effect on EMT but inhib... BeFree 25979438 Detail
<0.001 Nonorganic psychosis NA BeFree Detail
<0.001 Early gastric cancer In the present study, we compared the time course of messenger RNA (mRNA) expres... BeFree 25784376 Detail
<0.001 Arrhythmogenic Right Ventricular Dysplasia NA BeFree Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
<0.001 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
<0.001 Skin callus Last, we showed that EtOH exposure reduces the TGF-β1 protein levels in mouse fr... BeFree 25713073 Detail
0.027 Malignant neoplasm of prostate P21 activated kinase-1 mediates transforming growth factor β1-induced prostate c... BeFree,GAD 25746720 Detail
0.002 gingival overgrowth NA GAD Detail
0.003 Hematologic Neoplasms NA BeFree,GAD Detail
0.002 multiple system atrophy NA GAD Detail
0.002 thrombophilia NA GAD Detail
0.120 Non-alcoholic Fatty Liver Disease NA CTD_human Detail
<0.001 Idiopathic crescentic glomerulonephritis NA BeFree Detail
<0.001 Chronic rejection of renal transplant NA BeFree Detail
<0.001 Skeletal dysplasia NA BeFree Detail
<0.001 Sinus Node Dysfunction (disorder) NA BeFree Detail
<0.001 Ichthyosis bullosa of Siemens NA BeFree Detail
0.002 endometrial carcinoma NA BeFree Detail
<0.001 Respiratory distress NA BeFree Detail
0.005 dementia NA GAD,LHGDN Detail
<0.001 Necrotizing Enterocolitis NA BeFree Detail
<0.001 Cerebrovascular amyloidosis NA BeFree Detail
<0.001 Granulomatosis NA BeFree Detail
0.121 Peritoneal Fibrosis NA BeFree,CTD_human Detail
<0.001 Bilateral cataracts (disorder) NA BeFree Detail
<0.001 Corneal fibrosis NA BeFree Detail
<0.001 Pervasive Development Disorder NA BeFree Detail
0.080 Metabolic syndrome X NA RGD Detail
0.002 Neurodegenerative Disorders NA GAD Detail
0.015 Hepatitis B, Chronic SUMMARY To detect the expression of pro-fibrotic molecules, such as heat shock p... BeFree,GAD,LHGDN 25111595 Detail
0.036 Hepatitis C, Chronic NA BeFree,GAD,LHGDN Detail
<0.001 Mood Disorders NA BeFree Detail
<0.001 Idiopathic hypercalciuria TGF‑β1, BMP2 and OPN expression levels in patients with IH were all significantl... BeFree 25394514 Detail
0.008 Malignant neoplasm of esophagus NA BeFree,GAD Detail
0.001 Thyroid carcinoma NA BeFree Detail
<0.001 sexual dysfunction NA BeFree Detail
<0.001 Squamous cell carcinoma of skin NA BeFree Detail
0.120 endomyocardial fibrosis NA CTD_human Detail
<0.001 Malignant glioma NA BeFree Detail
0.002 Osteosarcoma of bone TGF-β1 promotes osteosarcoma cell migration and invasion through the miR-143-ver... BeFree 25562163 Detail
0.002 Osteosarcoma of bone Correlation between TGF-β1 gene 29 T > C single nucleotide polymorphism and clin... BeFree 25663491 Detail
0.010 Carcinogenesis These results suggest that the overexpressed TGF-β1 in inflammation triggers the... BeFree 25172416 Detail
0.010 Carcinogenesis Transforming growth factor-β1 is a member of a large class of polypeptides that ... BeFree 25409890 Detail
0.010 Carcinogenesis Functional enrichment analyses revealed the transcription factor MITF (p < 3.6 ×... BeFree 25890285 Detail
0.002 subcutaneous fibrosis NA GAD Detail
<0.001 hyperhomocysteinemia NA BeFree Detail
0.009 prostate carcinoma Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell ... BeFree 25224321 Detail
0.009 prostate carcinoma P21 activated kinase-1 mediates transforming growth factor β1-induced prostate c... BeFree 25746720 Detail
0.002 hepatopulmonary syndrome NA GAD Detail
0.120 Ventricular Remodeling NA CTD_human Detail
0.005 Hashimoto Disease NA BeFree,GAD,LHGDN Detail
0.004 Epithelial ovarian cancer NA BeFree,GAD Detail
<0.001 Progressive Neoplastic Disease NA BeFree Detail
0.019 breast carcinoma Accordingly, in this manuscript, we demonstrate that the inhibition of GD3S usin... BeFree 25109336 Detail
0.019 breast carcinoma Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promo... BeFree 25327287 Detail
0.019 breast carcinoma No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Cauca... BeFree 25374198 Detail
0.019 breast carcinoma Activating transcription factor (ATF-3) is a stress response gene and is induced... BeFree 25380580 Detail
0.019 breast carcinoma Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem... BeFree 25531323 Detail
0.019 breast carcinoma These findings establish the first link between HMGA1 and TGF-β1 in breast cance... BeFree 25572132 Detail
0.019 breast carcinoma Two polymorphisms in the TGF-β1 gene (-509C/T and 869T/C) were described to infl... BeFree 25813152 Detail
0.019 breast carcinoma HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program f... BeFree 26041563 Detail
0.019 breast carcinoma Increased VEGF-A, IGF-I, IGF-IR and TGF-β1 expressions were detected in breast c... BeFree 26232605 Detail
<0.001 Hemophilia, NOS Plant-based oral tolerance to hemophilia therapy employs a complex immune regula... BeFree 25700434 Detail
0.001 Secondary malignant neoplasm of lymph node NA BeFree Detail
0.006 colon carcinoma TSA or VPA induced a mesenchymal phenotype in the colon carcinoma cells and thes... BeFree 25813246 Detail
0.007 stomach carcinoma The HER-2 positive SGC-7901 secreted more transforming growth factor beta 1 (TGF... BeFree 25613482 Detail
0.003 Carcinoma of bladder Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and incr... BeFree 25017509 Detail
0.003 Carcinoma of bladder Altered gene expression profile after exposure to transforming growth factor β1 ... BeFree 25132950 Detail
0.003 Carcinoma of bladder Evaluation of transforming growth factor-β1 suppress Pokemon/epithelial-mesenchy... BeFree 25722217 Detail
<0.001 airway disease NA BeFree Detail
0.001 Central neuroblastoma NA BeFree Detail
<0.001 Dissecting aneurysm of the thoracic aorta NA BeFree Detail
<0.001 Microalbuminuria NA BeFree Detail
0.002 Malignant neoplasm of kidney NA GAD Detail
<0.001 Chronic lung disease NA BeFree Detail
<0.001 Benign thyroid nodule In this study, we demonstrated that expression of TGF-β1 but not TGF-β2 is signi... BeFree 25927212 Detail
<0.001 biliary tract cancer NA BeFree Detail
<0.001 Juvenile Neuronal Ceroid Lipofuscinosis NA BeFree Detail
<0.001 CADASIL Syndrome We also detected increased levels of the TGF-β prodomain (also known as latency-... BeFree 25190493 Detail
<0.001 Malignant Squamous Cell Neoplasm NA BeFree Detail
0.002 Multiple Sclerosis, Relapsing-Remitting NA GAD Detail
<0.001 thrombocytosis NA BeFree Detail
<0.001 Oestrogen deficiency Dysregulated IL-4R, IL-2RG, TGF-β1 and CD74 may mediate the interplay of immune ... BeFree 25565391 Detail
<0.001 Endothelial dysfunction NA BeFree Detail
<0.001 Acute GVH disease NA BeFree Detail
0.003 Thrombocytopenic purpura NA LHGDN Detail
<0.001 breast adenocarcinoma NA BeFree Detail
<0.001 latent infection NA BeFree Detail
<0.001 Muscle fibrosis NA BeFree Detail
<0.001 Intraepithelial Neoplasia NA BeFree Detail
0.003 Cardiomyopathies NA BeFree,GAD Detail
0.011 ovarian neoplasm NA BeFree,LHGDN Detail
0.002 autoimmune thyroiditis NA GAD Detail
<0.001 Carcinogenesis, Radiation NA BeFree Detail
<0.001 Renal ischaemia NA BeFree Detail
<0.001 Metastatic Prostate Carcinoma NA BeFree Detail
<0.001 Ischemic stroke NA BeFree Detail
0.004 Acute coronary syndrome Association of a transforming growth factor-β1 polymorphism with acute coronary ... BeFree,LHGDN 24737521 Detail
<0.001 alveolar echinococcosis NA BeFree Detail
0.002 Spondylarthropathies NA GAD Detail
0.005 Papillomavirus Infections NA BeFree,GAD Detail
<0.001 Anterior subcapsular cataract NA BeFree Detail
0.003 Invasive Ductal Breast Carcinoma NA BeFree,GAD Detail
0.003 Gestational Trophoblastic Neoplasms NA BeFree,GAD Detail
0.004 Malignant neoplasm of ovary Furthermore, our results also provided evidence concerning the role of inflammat... BeFree 24931361 Detail
0.004 Malignant neoplasm of ovary Among numerous EMT-associated transcripts, Smad7 is considered to be an inhibito... BeFree 25333457 Detail
<0.001 Skin toxicity NA BeFree Detail
0.001 Squamous cell carcinoma of the head and neck Thus, our findings suggest that cytoplasmic DRAK1 increases tumorigenic potentia... BeFree 25531329 Detail
0.002 Ductal Carcinoma NA GAD Detail
0.005 Stenosis NA GAD,LHGDN Detail
<0.001 High grade surface osteosarcoma NA BeFree Detail
0.002 Blood pressure finding NA GAD Detail
0.002 Systemic arterial pressure NA GAD Detail
<0.001 Acute mucositis NA BeFree Detail
<0.001 Inflammatory disorder NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 Chronic myeloproliferative disorder NA BeFree Detail
<0.001 Adenoma of large intestine NA BeFree Detail
<0.001 chronic venous insufficiency NA BeFree Detail
0.002 Death (finding) NA GAD Detail
<0.001 Eosinophilic disorder NA BeFree Detail
<0.001 Liver regeneration disorder NA BeFree Detail
<0.001 Adenocarcinoma of large intestine NA BeFree Detail
<0.001 Hormone refractory prostate cancer NA BeFree Detail
<0.001 Invasive Carcinoma NA BeFree Detail
0.002 pancreatic ductal adenocarcinoma Taken together, our findings demonstrated that TGF-β1-induced Kindlin-2 expressi... BeFree 25724625 Detail
<0.001 Testicular Germ Cell Tumor NA BeFree Detail
<0.001 Epithelioma NA BeFree Detail
<0.001 Cardiomyopathy, Familial Idiopathic NA BeFree Detail
0.042 Mammary Neoplasms Correlations between the expression levels of TGFβ1 and the miR181/BRCA1 axis we... BeFree,GAD,LHGDN 25103497 Detail
<0.001 Desmoplastic NA BeFree Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Cancer Cell Growth NA BeFree Detail
<0.001 Tumor Angiogenesis Reduction in tumor volume was associated not only with promotion of tumor apopto... BeFree 25275595 Detail
<0.001 Tumor Promotion NA BeFree Detail
<0.001 Xenograft Model DRAK1 depletion enhanced TGF-β1-induced growth inhibition in vitro and suppresse... BeFree 25531329 Detail
0.150 colorectal cancer CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated su... BeFree,GAD,GWASCAT 25268580 Detail
0.150 colorectal cancer Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer... BeFree,GAD,GWASCAT 25884904 Detail
0.085 Sjogren's syndrome NA GAD,MGD Detail
<0.001 Morphea NA BeFree Detail
<0.001 Neoplasms, Intracranial NA BeFree Detail
0.003 Pneumocystis jiroveci pneumonia NA LHGDN Detail
<0.001 hypereosinophilic syndrome NA BeFree Detail
<0.001 Non-Malignant Ascites Adverse Event NA BeFree Detail
0.006 Renal Insufficiency NA BeFree,GAD Detail
0.002 Delayed Graft Function NA GAD Detail
<0.001 Adenocarcinoma, Endometrioid NA BeFree Detail
<0.001 Glioblastoma multiforme Moreover, application of active AR ligand 5α-dihydrotestosterone (DHT) significa... BeFree 25315188 Detail
<0.001 Glioblastoma multiforme Depletion of SMAD2, but not SMAD3, significantly abolished the inhibitory effect... BeFree 25832460 Detail
0.006 Cirrhosis NA BeFree,GAD Detail
<0.001 Disorder characterized by eosinophilia NA BeFree Detail
0.003 Benign Prostatic Hyperplasia NA BeFree Detail
<0.001 Uterine Corpus Carcinosarcoma NA BeFree Detail
<0.001 Induced Cataract NA BeFree Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 PERIODONTITIS, LOCALIZED AGGRESSIVE A total of 84 patients with generalized aggressive periodontitis (GAP,n:29), gen... BeFree 25638399 Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
0.012 Idiopathic Pulmonary Fibrosis Taken together, our data identify a novel mechanism for downstream signal transd... BeFree,GAD,LHGDN 24515257 Detail
0.012 Idiopathic Pulmonary Fibrosis SOCS-1 mRNA expression was significantly decreased in the PBMC of IPF patients c... BeFree,GAD,LHGDN 24890164 Detail
0.012 Idiopathic Pulmonary Fibrosis FOXF1 expression was induced by the antifibrotic mediator prostaglandin E2 and r... BeFree,GAD,LHGDN 25260753 Detail
0.012 Idiopathic Pulmonary Fibrosis LXA4 also significantly inhibited FBS-dependent proliferation and TGF-β1-depende... BeFree,GAD,LHGDN 26276873 Detail
<0.001 Ribbing disease NA BeFree Detail
<0.001 Chromosome 11p11.2 Deletion Syndrome NA BeFree Detail
<0.001 MYELOPROLIFERATIVE SYNDROME, TRANSIENT NA BeFree Detail
<0.001 TIBIAL MUSCULAR DYSTROPHY, TARDIVE NA BeFree Detail
<0.001 IMMUNE SUPPRESSION NA BeFree Detail
<0.001 Smith-McCort dysplasia NA BeFree Detail
<0.001 peeling skin syndrome NA BeFree Detail
<0.001 Myeloproliferative disorder, chronic, with eosinophilia It was also noted that high levels of IL-10, TGF-β1 and CCL17 were observed in M... BeFree 25371165 Detail
<0.001 CYSTIC FIBROSIS MODIFIER 1 NA BeFree Detail
<0.001 arterial tortuosity syndrome NA BeFree Detail
0.002 Venous thromboembolism NA GAD Detail
<0.001 EHLERS-DANLOS SYNDROME, PROGEROID FORM NA BeFree Detail
0.120 Copper-Overload Cirrhosis NA CTD_human Detail
<0.001 uterine corpus cancer NA BeFree Detail
<0.001 Osteophyte NA BeFree Detail
0.006 coronary artery disease Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Gr... BeFree,GAD 25155040 Detail
0.005 Precursor Cell Lymphoblastic Leukemia Lymphoma NA GAD Detail
<0.001 Urothelial Carcinoma Given that the tumor-promoting inflammation has been previously established in s... BeFree 24448750 Detail
<0.001 eyelids (symptom) In contrast, the mean (SD; 96% CI) fold change of expression of TGF-β1 messenger... BeFree 26204109 Detail
0.163 liver carcinoma Transforming growth factor-β1 (TGF-β1) potently inhibits human hepatocellular ca... BeFree,CTD_human,GAD,LHGDN 24960176 Detail
0.163 liver carcinoma MEF2 transcription factors promotes EMT and invasiveness of hepatocellular carci... BeFree,CTD_human,GAD,LHGDN 25087096 Detail
0.163 liver carcinoma MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma. BeFree,CTD_human,GAD,LHGDN 25162823 Detail
0.163 liver carcinoma Also Dp44mT attenuated the TGF-β1-induced EMT in HCC having low metastatic poten... BeFree,CTD_human,GAD,LHGDN 25261367 Detail
0.163 liver carcinoma In order to find out whether NH4Cl may inhibit the autophagy in rapamycin-treate... BeFree,CTD_human,GAD,LHGDN 25342595 Detail
0.163 liver carcinoma Transforming growth factor-β1 gene expression in hepatocellular carcinoma: a pre... BeFree,CTD_human,GAD,LHGDN 25475758 Detail
0.163 liver carcinoma The high correlation between MUC1 and TGF-β1 or p-Smad3L (Ser-213) expression wa... BeFree,CTD_human,GAD,LHGDN 25526895 Detail
0.163 liver carcinoma These results suggest that SIRT6 is required for TGF-β1/H2O2/HOCl to enhance the... BeFree,CTD_human,GAD,LHGDN 25683165 Detail
0.163 liver carcinoma ZEB2 promotes vasculogenic mimicry by TGF-β1 induced epithelial-to-mesenchymal t... BeFree,CTD_human,GAD,LHGDN 25818166 Detail
0.163 liver carcinoma TGF-β1 polymorphism 509 C>T is associated with an increased risk for hepatocellu... BeFree,CTD_human,GAD,LHGDN 25966218 Detail
0.002 Chronic idiopathic neutropenia NA GAD Detail
<0.001 Chronic kidney disease stage 5 Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with... BeFree 25871499 Detail
<0.001 Idiopathic Interstitial Pneumonias NA BeFree Detail
0.003 Allergic rhinitis (disorder) NA BeFree,GAD Detail
0.120 Acute kidney injury NA CTD_human Detail
<0.001 Loeys-Dietz syndrome Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patient... BeFree 25113270 Detail
<0.001 Steatohepatitis NA BeFree Detail
<0.001 Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis NA BeFree Detail
<0.001 Liver Disease Associated with Cystic Fibrosis NA BeFree Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
0.007 Chronic ulcerative colitis NA GAD Detail
<0.001 Moyamoya disease 1 NA BeFree Detail
<0.001 Nasopharyngeal carcinoma NA BeFree Detail
<0.001 Plaque, Amyloid Following an oral treatment of 10 days, Icariin significantly attenuated Aβ depo... BeFree 25101849 Detail
0.008 Prostatic Hyperplasia NA GAD,LHGDN Detail
0.002 Deficiency of glucose-6-phosphate dehydrogenase NA GAD Detail
<0.001 Pulmonary arterial hypertension NA BeFree Detail
<0.001 Idiopathic pulmonary arterial hypertension NA BeFree Detail
<0.001 Immunoglobulin G4 related sclerosing disease Real-time polymerase chain reaction analysis confirmed the significant upregulat... BeFree 24390219 Detail
<0.001 Nonalcoholic Steatohepatitis NA BeFree Detail
<0.001 Ischemic Cerebrovascular Accident NA BeFree Detail
0.013 myelodysplastic syndrome NA BeFree,GAD,LHGDN Detail
0.007 Juvenile arthritis NA GAD Detail
0.007 granulomatosis with polyangiitis NA GAD Detail
<0.001 Progressive cGVHD NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms In the TNBC group, metastasis and poor response to treatment were significantly ... BeFree 26232605 Detail
<0.001 aortic valve disease 2 Similarly, tsTGF-β1 levels were elevated in MFS (P = 0.003) and in BAVD (P = 0.0... BeFree 25113270 Detail
<0.001 aortic valve disease 2 Confocal microscopy analysis showed a higher colocalization of latency associate... BeFree 25745062 Detail
<0.001 Allergic sensitization NA BeFree Detail
<0.001 Intracranial glioma NA BeFree Detail
<0.001 Mammary adenocarcinoma NA BeFree Detail
0.037 Infection NA GAD,LHGDN Detail
<0.001 Pneumonitis NA BeFree Detail
<0.001 Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia NA BeFree Detail
<0.001 Congenital Abnormality NA BeFree Detail
0.122 Spontaneous abortion NA CTD_human,GAD Detail
0.002 Abortion, Habitual NA GAD Detail
0.148 adenocarcinoma NA BeFree,CTD_human,GAD,LHGDN Detail
0.006 adenoma NA BeFree,GAD,LHGDN Detail
0.004 Primary myelofibrosis NA BeFree,LHGDN Detail
0.009 Albuminuria NA GAD Detail
<0.001 Alcoholic Intoxication, Chronic Assessment of the frequency of the transforming growth factor beta-1 sequence po... BeFree 25710054 Detail
<0.001 alopecia areata NA BeFree Detail
0.002 extrinsic allergic alveolitis NA GAD Detail
0.026 Alzheimer's disease An impairment of the transforming growth factor-β1 (TGF-β1) signaling pathway ha... BeFree,GAD,LHGDN 24347181 Detail
0.003 amyloidosis Icariin ameliorates neuropathological changes, TGF-β1 accumulation and behaviora... BeFree,LHGDN 25101849 Detail
0.002 amyotrophic lateral sclerosis NA GAD Detail
0.090 Malignant neoplasm of breast Confirmed BC risk SNPs rs17468277 (CASP8), rs1982073 (TGFB1), rs2981582 (FGFR2),... BeFree 22532573 Detail
0.019 breast carcinoma Confirmed BC risk SNPs rs17468277 (CASP8), rs1982073 (TGFB1), rs2981582 (FGFR2),... BeFree 22532573 Detail
<0.001 Anaplasia Here, we show that expression of the transcription factor Basonuclin-1 (Bnc1) mo... BeFree 24662832 Detail
<0.001 aplastic anemia NA BeFree Detail
0.002 Refractory anemias NA GAD Detail
<0.001 Anemia, Sickle Cell NA BeFree Detail
<0.001 Aneurysm NA BeFree Detail
0.002 Angina Pectoris NA GAD Detail
0.002 angioedema NA GAD Detail
0.010 Anoxia NA GAD,LHGDN Detail
0.120 aortic valve insufficiency NA CTD_human Detail
0.002 arteriosclerosis Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... BeFree 25740578 Detail
0.005 arthritis NA GAD Detail
0.024 rheumatoid arthritis In conclusion, the TT genotype of TGFβ1 T869C was associated with RA risk in the... BeFree,GAD,LHGDN 24840097 Detail
0.024 rheumatoid arthritis Western blotting revealed the expression of C/EBPβ-LAP and -LIP in RA-FLS. BeFree,GAD,LHGDN 25811130 Detail
0.024 rheumatoid arthritis MTHFR, TGFβ1, and TNFB polymorphisms don't appear to be clinically useful geneti... BeFree,GAD,LHGDN 25981594 Detail
0.002 asbestosis NA GAD Detail
0.291 asthma Identification and association of the single nucleotide polymorphisms, C-509T, C... BeFree,CTD_human,GAD,LHGDN,RGD 25119113 Detail
0.291 asthma We highlight TGF-β1 as a potential future therapeutic target in severe asthma in... BeFree,CTD_human,GAD,LHGDN,RGD 25240764 Detail
0.291 asthma Association of transforming growth factor-Beta 1 promoter variant -509 c/t with ... BeFree,CTD_human,GAD,LHGDN,RGD 25359706 Detail
0.291 asthma In conclusion, these results suggest a role of TGF-β1 in olive-pollen sensitizat... BeFree,CTD_human,GAD,LHGDN,RGD 25759826 Detail
<0.001 Astrocytoma Studies in vitro and in vivo using TGF-β1 and TGFB1I1 shRNA demonstrated that TG... BeFree 25333259 Detail
0.015 atherosclerosis Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... BeFree,GAD,LHGDN 25740578 Detail
0.002 atrial fibrillation NA GAD Detail
0.006 Autoimmune Diseases NA BeFree,GAD Detail
<0.001 Melanoma, B16 NA BeFree Detail
<0.001 Bacteremia NA BeFree Detail
0.005 Bacterial Infections NA LHGDN Detail
0.005 Behcet Syndrome NA BeFree,GAD Detail
0.127 berylliosis NA CTD_human,GAD,LHGDN Detail
0.002 Biliary Tract Neoplasm NA GAD Detail
<0.001 bipolar disorder NA BeFree Detail
0.002 bird fancier's lung NA GAD Detail
0.014 Malignant neoplasm of urinary bladder Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and incr... BeFree,GAD 25017509 Detail
0.014 Malignant neoplasm of urinary bladder Altered gene expression profile after exposure to transforming growth factor β1 ... BeFree,GAD 25132950 Detail
0.014 Malignant neoplasm of urinary bladder Evaluation of transforming growth factor-β1 suppress Pokemon/epithelial-mesenchy... BeFree,GAD 25722217 Detail
<0.001 bladder neck obstruction MiR-133 modulates TGF-β1-induced bladder smooth muscle cell hypertrophic and fib... BeFree 25451078 Detail
0.003 Bladder Neoplasm NA LHGDN Detail
<0.001 Bone Diseases, Developmental NA BeFree Detail
<0.001 borderline personality disorder NA BeFree Detail
<0.001 Brain Diseases NA BeFree Detail
0.090 Malignant neoplasm of breast Accordingly, in this manuscript, we demonstrate that the inhibition of GD3S usin... BeFree,GAD 25109336 Detail
0.090 Malignant neoplasm of breast Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promo... BeFree,GAD 25327287 Detail
0.090 Malignant neoplasm of breast No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Cauca... BeFree,GAD 25374198 Detail
0.090 Malignant neoplasm of breast Activating transcription factor (ATF-3) is a stress response gene and is induced... BeFree,GAD 25380580 Detail
0.090 Malignant neoplasm of breast Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem... BeFree,GAD 25531323 Detail
0.090 Malignant neoplasm of breast These findings establish the first link between HMGA1 and TGF-β1 in breast cance... BeFree,GAD 25572132 Detail
0.090 Malignant neoplasm of breast Two polymorphisms in the TGF-β1 gene (-509C/T and 869T/C) were described to infl... BeFree,GAD 25813152 Detail
0.090 Malignant neoplasm of breast HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program f... BeFree,GAD 26041563 Detail
0.090 Malignant neoplasm of breast Increased VEGF-A, IGF-I, IGF-IR and TGF-β1 expressions were detected in breast c... BeFree,GAD 26232605 Detail
<0.001 bronchiectasis NA BeFree Detail
0.002 Bronchiolitis, Viral NA GAD Detail
0.003 bronchitis NA LHGDN Detail
0.004 bronchopulmonary dysplasia NA BeFree,GAD Detail
0.013 brucellosis TGFβ1 genetic variants are associated with an increased risk of acute brucellosi... BeFree,GAD,LHGDN 25738611 Detail
0.003 Carcinoid Tumor NA BeFree,LHGDN Detail
0.002 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 female breast carcinoma NA BeFree Detail
<0.001 Adenocarcinoma of prostate NA BeFree Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.003 basal cell carcinoma NA LHGDN Detail
0.009 Non-small cell lung carcinoma Plasma levels of TGF-β1 may be a marker for predicting response to EGFR-TKIs and... BeFree,GAD 24378285 Detail
0.009 Non-small cell lung carcinoma Transforming growth factor-β1-induced epithelial to mesenchymal transition incre... BeFree,GAD 25323156 Detail
0.009 Non-small cell lung carcinoma FOXM1 regulated by ERK pathway mediates TGF-β1-induced EMT in NSCLC. BeFree,GAD 25700356 Detail
0.009 Non-small cell lung carcinoma After stimulating with TGF-β1, almost all A549 cells and Luca 1 cells (Non-small... BeFree,GAD 25987100 Detail
0.005 renal cell carcinoma Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Rena... BeFree,LHGDN 25909813 Detail
Annotation

Annotations

DescrptionSourceLinks
Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacanthomas and squamous ... DisGeNET Detail
For C/EBPβ, only the abundant full-length isoform (C/EBPβ-1, LAP*, 55 kD) was reduced, whereas the s... DisGeNET Detail
We incubated the p16-positive CERV196 and p16-negative HNSCC22B SCC cell lines with EGF and EGF/TGFβ... DisGeNET Detail
Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
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CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory... DisGeNET Detail
Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smad... DisGeNET Detail
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Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Growth Factor-β1 With ... DisGeNET Detail
Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Growth Factor-β1 With ... DisGeNET Detail
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Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression in muscle of strictu... DisGeNET Detail
TAK1 inhibition or silencing significantly reduced TGF-β1-stimulated collagen production and normali... DisGeNET Detail
The data indicate that the overexpression of survivin in AdCC is related to HIF-1α, TGF-β1 and TFE3. DisGeNET Detail
Therefore, we propose that TGF-β1-induced mucociliary dysfunction in CF airways is associated with B... DisGeNET Detail
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Tacrolimus (FK506) ointment has been reported to be effective for treating AD as well as some TGF-β1... DisGeNET Detail
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Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in Type 1 Diabetes. DisGeNET Detail
Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with Type 2 Diabetes and... DisGeNET Detail
Our findings suggest that TGF-β1 and IL-10 polymorphisms are involved in complications and comorbidi... DisGeNET Detail
In cultured podocytes, various cytokines related to diabetic nephropathy including TGF-β1, TNF-α, an... DisGeNET Detail
Targeting cellular drivers and counter-regulators of hyperglycaemia- and transforming growth factor-... DisGeNET Detail
This Review discusses current understanding of the function of miRNAs in CKD, focusing on functions ... DisGeNET Detail
Transforming growth factor-beta1 (TGF-β1), a ubiquitously expressed pro-fibrotic cytokine plays a pi... DisGeNET Detail
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Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codon 25C/G polymorphism... DisGeNET Detail
We cautiously conclude that TGFβ1 inhibition with losartan deserves further evaluation in the clinic... DisGeNET Detail
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The mechanisms may include the following pathways: [TGFB1 or TNFA]-[IL1B]-[pre-eclampsia]; [TNFA or ... DisGeNET Detail
TGFB1 Functional Gene Polymorphisms (C-509T and T869C) in the Maternal Susceptibility to Pre-eclamps... DisGeNET Detail
Tacrolimus (FK506) ointment has been reported to be effective for treating AD as well as some TGF-β1... DisGeNET Detail
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In conclusion, the peritoneum, and in particular, the peritoneal mesothelium, is a source of TGF-β1 ... DisGeNET Detail
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FOXP3 mRNA levels were correlated positively with TGF-β1 and IL-10 mRNA levels in the H pylori(+) ga... DisGeNET Detail
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Proposed test statistics are applied to NHANES III data to test for associations between the locus A... DisGeNET Detail
Proposed test statistics are applied to NHANES III data to test for associations between the locus A... DisGeNET Detail
Impact of TGF-β1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis. DisGeNET Detail
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The TGF-β1-509T/C-dominant model for the C allele was significantly associated with proteinuria (≥1.... DisGeNET Detail
This meta-analysis does not support the hypothesis that TGF-β1 gene-509C/T polymorphism is a risk fa... DisGeNET Detail
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Arg25Pro (c.915G>C) polymorphism of transforming growth factor β1 gene increases the risk of develop... DisGeNET Detail
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Transforming growth factor-β(1) (TGF-β(1)) is an important regulator of fibrogenesis in heart diseas... DisGeNET Detail
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Up-regulation was evident for muscle LIM protein (Mlp), desmin, and heart failure (natriuretic pepti... DisGeNET Detail
Up-regulation was evident for muscle LIM protein (Mlp), desmin, and heart failure (natriuretic pepti... DisGeNET Detail
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Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response includ... DisGeNET Detail
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High levels of periostin in patients with acute or chronic hepatitis correlated with TGF-β1 and TGF-... DisGeNET Detail
High levels of periostin in patients with acute or chronic hepatitis correlated with TGF-β1 and TGF-... DisGeNET Detail
Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antige... DisGeNET Detail
The relationship between hepatitis B virus (HBV) load and levels of transforming growth factor beta ... DisGeNET Detail
High levels of periostin in patients with acute or chronic hepatitis correlated with TGF-β1 and TGF-... DisGeNET Detail
In this study, we confirmed that the TGF-β1 polymorphism 509 C>T is associated with the risk of HCC ... DisGeNET Detail
HBV and hepatitis C virus (HCV) serological markers, sFas and TGF-β1 levels, and HBV load were evalu... DisGeNET Detail
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Association of TGFB1 29C/T and IL6 -572G/C polymorphisms with developmental hip dysplasia: a case-co... DisGeNET Detail
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Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and F... DisGeNET Detail
Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and F... DisGeNET Detail
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Targeting cellular drivers and counter-regulators of hyperglycaemia- and transforming growth factor-... DisGeNET Detail
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Hypertension is associated with increased expression of FABP3, FAS, FN1, IL1R2, LPL, SERPINE1, TGFB1... DisGeNET Detail
Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Growth Factor-β1 With ... DisGeNET Detail
Hypertension was associated with the CC genotype and C allele for IL-10 -592C/A polymorphism (p = 0.... DisGeNET Detail
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Association of MSX1 and TGF-β1 genetic polymorphisms with hypodontia: meta-analysis. DisGeNET Detail
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Pattern of TGFbeta receptor 1 expression differs between kras-mutated keratoacanthomas and squamous ... DisGeNET Detail
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Diabetic retinopathy was associated with GG genotype and G allele in TGF-β1 codon 25C/G polymorphism... DisGeNET Detail
Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with Type 2 Diabetes and... DisGeNET Detail
Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in Type 1 Diabetes. DisGeNET Detail
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We propose that this mechanism is activated by a ligand-receptor interaction between TGF-β1, found i... DisGeNET Detail
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Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-imm... DisGeNET Detail
Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-imm... DisGeNET Detail
The aim of this study was to investigate the clinical significance of serum TGF-β1 level and TGF-β1 ... DisGeNET Detail
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Long-term effects of three Tiao-Bu Fei-Shen therapies on NF-κB/TGF-β1/smad2 signaling in rats with c... DisGeNET Detail
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Single nucleotide polymorphism T869C of transforming growth factor-beta 1 gene and systemic lupus er... DisGeNET Detail
Renal gene expression levels of transforming growth factor β-1 (TGFB1), and collagen I (COL1) were s... DisGeNET Detail
Single nucleotide polymorphism T869C of transforming growth factor-beta 1 gene and systemic lupus er... DisGeNET Detail
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The HER-2 positive SGC-7901 secreted more transforming growth factor beta 1 (TGF-β1) and resultantly... DisGeNET Detail
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In contrast to specific clinical features of MFS, FBN1 in-frame mutations (P = 0.019) were associate... DisGeNET Detail
The expression of PRRs (Toll-like receptors and melanoma differentiation-associated gene 5) was indu... DisGeNET Detail
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In addition to oligodontia and short stature, both sisters have mitral valve prolapse, suggesting a ... DisGeNET Detail
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Transforming growth factor-β1 gene polymorphism in mycosis fungoides. DisGeNET Detail
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Transforming growth factor‑β1 (TGF‑β1) is involved in the migration and metastases of bladder cancer... DisGeNET Detail
Furthermore, the enrichment of LAP⁺ Treg population in peripheral blood mononuclear cells (PBMCs) of... DisGeNET Detail
These data suggest that a metabolic transition that suppresses lipogenesis and favors energy product... DisGeNET Detail
The processes of EMT and metastasis are highly regulated by a double-negative feedback loop consisti... DisGeNET Detail
We conclude that tumor-derived OPN engenders MSC-to-CAF transformation in the microenvironment to pr... DisGeNET Detail
TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma. DisGeNET Detail
However, the underlying mechanism of TGF-β1-mediated metastasis remains unclear. DisGeNET Detail
The morbidity and metastasis of osteosarcoma are relevant to TGF-β1 gene 29 T > C single nucleotide ... DisGeNET Detail
IGF-IR and VEGF-A overexpression was observed to be correlated with TGF-β1 expression and all of the... DisGeNET Detail
Our new findings provided evidence that, resveratrol could inhibit EMT in CRC through TGF-β1/Smads s... DisGeNET Detail
Overexpression of EGR 1 gene with EGR 1 vector could decrease tumor cell migration capabilities sign... DisGeNET Detail
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The aim of this work was to establish an association between the single-nucleotide polymorphisms (SN... DisGeNET Detail
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The objective of the present study was to investigate the expression level and the localization of t... DisGeNET Detail
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Elevated thyroid nodule risks were associated with the minor alleles of RET S836S (rs1800862, P = 0.... DisGeNET Detail
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These results suggest that the Tgf-β1 canonical signaling was activated to induce HtrA1 in the artic... DisGeNET Detail
Murine and human chondrocyte cell lines, primary bovine and human chondrocytes, and cartilage explan... DisGeNET Detail
To determine the effects of Bushenhuoxue formula (BHF) on interleukin-1 beta (IL-1β), transforming g... DisGeNET Detail
Transforming growth factor-β1 (TGF-beta1) and interleukin-6 (IL-6) are included in pathogenesis of O... DisGeNET Detail
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The transforming growth factor-β1 (TGF-β1) gene polymorphisms (TGF-β1 T869C and TGF-β1 T29C) and sus... DisGeNET Detail
QEF-treated serum, particularly that containing moderate and high concentrations, appears to enhance... DisGeNET Detail
TGF-β1 promotes osteosarcoma cell migration and invasion through the miR-143-versican pathway. DisGeNET Detail
Correlation between TGF-β1 gene 29 T > C single nucleotide polymorphism and clinicopathological char... DisGeNET Detail
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Furthermore, our results also provided evidence concerning the role of inflammatory cytokines (IL-6,... DisGeNET Detail
Among numerous EMT-associated transcripts, Smad7 is considered to be an inhibitor, however its invol... DisGeNET Detail
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Transforming growth factor-β1 (TGF-β1) has been identified as one of the most important fibrogenic c... DisGeNET Detail
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Our results provide additional evidence that TGFB lays a key role in the early pathogenesis of polyc... DisGeNET Detail
Polymorphisms and haplotypes of the TGF-β1 gene are associated with risk of polycystic ovary syndrom... DisGeNET Detail
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Effects of TGFβ1 on control prostate cancer PC3 and DU145 cells and those with IPA 3 and siRNA media... DisGeNET Detail
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Transforming growth factor-β1 mediates psoriasis-like lesions via a Smad3-dependent mechanism in mic... DisGeNET Detail
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In some, but not all, studies, IL6 -174G/C (rs1800795) and TGFB1 869T/C (rs1982073) gene polymorphis... DisGeNET Detail
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At day 7, lung tissue acquired significant amounts of mtDNA deletions, translating into a significan... DisGeNET Detail
miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis. DisGeNET Detail
In vitro, fibroblast growth factor (FGF) 2 promotes myofibroblast differentiation and proliferation ... DisGeNET Detail
Particular attention has been paid to the understanding of the role of these proteases and their nat... DisGeNET Detail
In this study, the effects of PA on the transforming growth factor-β1 (TGF-β1)-mediated epithelial-m... DisGeNET Detail
Pulmonary fibrosis is an epithelial-mesenchymal disorder in which TGF-β1 plays a central role in pat... DisGeNET Detail
In the present study, we found that miR-153 expression was dysregulated in the lungs of mice with ex... DisGeNET Detail
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Both high expression of TGFB1 or COL1 tended to predict renal failure by univariate analysis. DisGeNET Detail
Circulating TGF-β1-Regulated miRNAs and the Risk of Rapid Progression to ESRD in Type 1 Diabetes. DisGeNET Detail
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We evaluated gene expression of TGF-β1, SMAD2, 3 and 7 in bronchoalveolar lavage (BAL) cells and per... DisGeNET Detail
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Immunohistochemistry (IHC) analyses displayed that the expression of Hsp47, TGF-β1 and CTGF was incr... DisGeNET Detail
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c-Abl silencing reduced the inhibitory effects of TGF-β1 on apoptosis in systemic sclerosis dermal f... DisGeNET Detail
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A significantly greater expression of TGF-β1 (p < 0.0001) was detected in the group of malignant thy... DisGeNET Detail
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We have recently shown that the single nucleotide polymorphism (SNP) rs1982073 of the TGFbeta1 gene ... DisGeNET Detail
Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk ... DisGeNET Detail
[Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk... DisGeNET Detail
Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk ... DisGeNET Detail
Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk ... DisGeNET Detail
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In the UUO model, administration of apelin significantly attenuated renal interstitial fibrosis, as ... DisGeNET Detail
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These findings provide the first insights into the BZ-regulated TGF-β1 and IL-10 expression in CTCL ... DisGeNET Detail
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Recent advances require further research of TGF-β1 receptor in EH. DisGeNET Detail
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Our results show that IL-17A G197A, IL-17F A7488G andIL23R +2199A/C polymorphisms have no effect on ... DisGeNET Detail
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Similarly, tsTGF-β1 levels were elevated in MFS (P = 0.003) and in BAVD (P = 0.006) vs patients with... DisGeNET Detail
Confocal microscopy analysis showed a higher colocalization of latency associated peptide and latent... DisGeNET Detail
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Here, we examined how TGF-β activates Src in H358 cells, a small cell lung carcinoma cell line. DisGeNET Detail
To our knowledge, this is the first report dealing with the relationship between TGF-β1 genotype and... DisGeNET Detail
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BMP-7 has a protective role against TGF-β1 in kidney fibrosis, whereas CTGF enhances TGF-β-mediated ... DisGeNET Detail
Furthermore, increased expression of nuclear peroxisome proliferator-activated receptor-α in proxima... DisGeNET Detail
Epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 is one of well-recognized factors contr... DisGeNET Detail
Transforming growth factor beta-1 (TGF-β1) is a cytokine with an important role in many steps of ren... DisGeNET Detail
Involvement of tumor suppressor ataxia telangiectasia mutated (ATM) in the TGF-β1 pathway related to... DisGeNET Detail
M2 macrophages released high levels TGFβ1 to suppress BMP7 to enhance EMT-induced renal fibrosis. DisGeNET Detail
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TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chines... DisGeNET Detail
TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma. DisGeNET Detail
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TAZ promoted epithelial-to-mesenchymal transition (EMT) and also was involved in TGF-β1-induced EMT ... DisGeNET Detail
TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer in Taiwanese. DisGeNET Detail
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HGF and TGFβ1 of bone-metastasis microenvironment acted co-ordinately, influencing non redundant pat... DisGeNET Detail
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Pathway analysis of the proteome measurements revealed a potential role for Transforming growth fact... DisGeNET Detail
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To date, no data have been reported concerning the influence of PTEN/PI3K signaling pathway on EMT i... DisGeNET Detail
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The molecular and cellular functions predicted for these CCA specific genes according to the Gene On... DisGeNET Detail
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TAZ promoted epithelial-to-mesenchymal transition (EMT) and also was involved in TGF-β1-induced EMT ... DisGeNET Detail
TGF-β1 and IL-10 single nucleotide polymorphisms as risk factors for oral cancer in Taiwanese. DisGeNET Detail
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Increased expression of NF-AT3 and NF-AT4 in the atria correlates with procollagen I carboxyl termin... DisGeNET Detail
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Surprisal analysis of mRNA time course data from lung and pancreatic cancer cells stimulated to unde... DisGeNET Detail
Overexpression of TGFβ1 enhanced the invasiveness of PCC cells, while inhibition of TGFβ1 decreased ... DisGeNET Detail
Silencing of Gli1 alone without external stimulus had no effect on EMT but inhibited transforming gr... DisGeNET Detail
Protein expressions of TGF-β1, Col-IV, and FN, and RIF index or cell apoptosis index in the GU group... DisGeNET Detail
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In this study, we demonstrated that expression of TGF-β1 but not TGF-β2 is significantly increased i... DisGeNET Detail
TRPV4 mRNA and protein were measured by RT-PCR and Western blot in patients and rat model of liver f... DisGeNET Detail
Fibrogenic cytokines, such as transforming growth factor-beta 1 play a central role in the progressi... DisGeNET Detail
Expression of heat shock protein 47, transforming growth factor-beta 1, and connective tissue growth... DisGeNET Detail
Our results showed that miR-181b expression was increased much higher than miR-181a expression in vi... DisGeNET Detail
Human and murine primary liver fibrosis-associated cells were isolated and treated with transforming... DisGeNET Detail
Smad2 protects against TGF-β1/Smad3-mediated collagen synthesis in human hepatic stellate cells duri... DisGeNET Detail
Further, miR-126 promoted TNF-a-induced TGF-β1 and collagen I mRNA expression in LX-2 cells. miR-126... DisGeNET Detail
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In addition to oligodontia and short stature, both sisters have mitral valve prolapse, suggesting a ... DisGeNET Detail
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A total of 84 patients with generalized aggressive periodontitis (GAP,n:29), generalized chronic per... DisGeNET Detail
In the present study, we compared the time course of messenger RNA (mRNA) expression of TGF-β1 and f... DisGeNET Detail
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Transforming growth factor-β1-induced epithelial-mesenchymal transition in human esophageal squamous... DisGeNET Detail
Taken together, our results suggest a novel and critical role of TIP30 involved in TGF-β1-induced ac... DisGeNET Detail
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Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
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We focused on TGFB1I1 (TGF-β1 induced transcript 1) whose expression correlation with WHO grades was... DisGeNET Detail
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Following an oral treatment of 10 days, Icariin significantly attenuated Aβ deposition, microglial a... DisGeNET Detail
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Validation of COL11A1/procollagen 11A1 expression in TGF-β1-activated immortalised human mesenchymal... DisGeNET Detail
Codon 10 C/T genotypic and C10 C allelic frequency of TGF-β1 polymorphisms were significantly higher... DisGeNET Detail
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A functional polymorphism C-509T in TGFβ-1 promoter contributes to susceptibility and prognosis of l... DisGeNET Detail
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Surprisal analysis of mRNA time course data from lung and pancreatic cancer cells stimulated to unde... DisGeNET Detail
Silencing of Gli1 alone without external stimulus had no effect on EMT but inhibited transforming gr... DisGeNET Detail
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In the present study, we compared the time course of messenger RNA (mRNA) expression of TGF-β1 and f... DisGeNET Detail
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Last, we showed that EtOH exposure reduces the TGF-β1 protein levels in mouse fracture callus. DisGeNET Detail
P21 activated kinase-1 mediates transforming growth factor β1-induced prostate cancer cell epithelia... DisGeNET Detail
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SUMMARY To detect the expression of pro-fibrotic molecules, such as heat shock protein 47 (Hsp47), t... DisGeNET Detail
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TGF‑β1, BMP2 and OPN expression levels in patients with IH were all significantly higher than those ... DisGeNET Detail
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TGF-β1 promotes osteosarcoma cell migration and invasion through the miR-143-versican pathway. DisGeNET Detail
Correlation between TGF-β1 gene 29 T > C single nucleotide polymorphism and clinicopathological char... DisGeNET Detail
These results suggest that the overexpressed TGF-β1 in inflammation triggers the deregulation of the... DisGeNET Detail
Transforming growth factor-β1 is a member of a large class of polypeptides that regulate the prolife... DisGeNET Detail
Functional enrichment analyses revealed the transcription factor MITF (p < 3.6 × 10(-16)) and growth... DisGeNET Detail
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Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing... DisGeNET Detail
P21 activated kinase-1 mediates transforming growth factor β1-induced prostate cancer cell epithelia... DisGeNET Detail
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Accordingly, in this manuscript, we demonstrate that the inhibition of GD3S using small hairpin RNA ... DisGeNET Detail
Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promotes tumor invasion a... DisGeNET Detail
No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Caucasian and Asian popul... DisGeNET Detail
Activating transcription factor (ATF-3) is a stress response gene and is induced by transforming gro... DisGeNET Detail
Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-a... DisGeNET Detail
These findings establish the first link between HMGA1 and TGF-β1 in breast cancer, providing further... DisGeNET Detail
Two polymorphisms in the TGF-β1 gene (-509C/T and 869T/C) were described to influence susceptibility... DisGeNET Detail
HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epith... DisGeNET Detail
Increased VEGF-A, IGF-I, IGF-IR and TGF-β1 expressions were detected in breast cancer. DisGeNET Detail
Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response includ... DisGeNET Detail
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TSA or VPA induced a mesenchymal phenotype in the colon carcinoma cells and these effects were augme... DisGeNET Detail
The HER-2 positive SGC-7901 secreted more transforming growth factor beta 1 (TGF-β1) and resultantly... DisGeNET Detail
Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and increased expression of ... DisGeNET Detail
Altered gene expression profile after exposure to transforming growth factor β1 in the 253J human bl... DisGeNET Detail
Evaluation of transforming growth factor-β1 suppress Pokemon/epithelial-mesenchymal transition expre... DisGeNET Detail
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In this study, we demonstrated that expression of TGF-β1 but not TGF-β2 is significantly increased i... DisGeNET Detail
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We also detected increased levels of the TGF-β prodomain (also known as latency-associated peptide, ... DisGeNET Detail
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Dysregulated IL-4R, IL-2RG, TGF-β1 and CD74 may mediate the interplay of immune changes and oestroge... DisGeNET Detail
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Association of a transforming growth factor-β1 polymorphism with acute coronary syndrome in a Chines... DisGeNET Detail
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Furthermore, our results also provided evidence concerning the role of inflammatory cytokines (IL-6,... DisGeNET Detail
Among numerous EMT-associated transcripts, Smad7 is considered to be an inhibitor, however its invol... DisGeNET Detail
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Thus, our findings suggest that cytoplasmic DRAK1 increases tumorigenic potential through inhibition... DisGeNET Detail
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Taken together, our findings demonstrated that TGF-β1-induced Kindlin-2 expression promotes PDAC pro... DisGeNET Detail
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Correlations between the expression levels of TGFβ1 and the miR181/BRCA1 axis were observed in prima... DisGeNET Detail
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Reduction in tumor volume was associated not only with promotion of tumor apoptosis but also with su... DisGeNET Detail
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DRAK1 depletion enhanced TGF-β1-induced growth inhibition in vitro and suppressed tumorigenicity in ... DisGeNET Detail
CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory... DisGeNET Detail
Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smad... DisGeNET Detail
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Moreover, application of active AR ligand 5α-dihydrotestosterone (DHT) significantly decreased the e... DisGeNET Detail
Depletion of SMAD2, but not SMAD3, significantly abolished the inhibitory effects of TGFβ1 on the gr... DisGeNET Detail
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A total of 84 patients with generalized aggressive periodontitis (GAP,n:29), generalized chronic per... DisGeNET Detail
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Taken together, our data identify a novel mechanism for downstream signal transduction induced by TG... DisGeNET Detail
SOCS-1 mRNA expression was significantly decreased in the PBMC of IPF patients compared with healthy... DisGeNET Detail
FOXF1 expression was induced by the antifibrotic mediator prostaglandin E2 and repressed by the prof... DisGeNET Detail
LXA4 also significantly inhibited FBS-dependent proliferation and TGF-β1-dependent collagen secretio... DisGeNET Detail
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It was also noted that high levels of IL-10, TGF-β1 and CCL17 were observed in MPE when compared to ... DisGeNET Detail
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Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Growth Factor-β1 With ... DisGeNET Detail
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Given that the tumor-promoting inflammation has been previously established in squamous cell carcino... DisGeNET Detail
In contrast, the mean (SD; 96% CI) fold change of expression of TGF-β1 messenger RNA (mRNA) decrease... DisGeNET Detail
Transforming growth factor-β1 (TGF-β1) potently inhibits human hepatocellular carcinoma (HCC) cell g... DisGeNET Detail
MEF2 transcription factors promotes EMT and invasiveness of hepatocellular carcinoma through TGF-β1 ... DisGeNET Detail
MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma. DisGeNET Detail
Also Dp44mT attenuated the TGF-β1-induced EMT in HCC having low metastatic potential. DisGeNET Detail
In order to find out whether NH4Cl may inhibit the autophagy in rapamycin-treated HCC cells through ... DisGeNET Detail
Transforming growth factor-β1 gene expression in hepatocellular carcinoma: a preliminary report. DisGeNET Detail
The high correlation between MUC1 and TGF-β1 or p-Smad3L (Ser-213) expression was shown in tumor tis... DisGeNET Detail
These results suggest that SIRT6 is required for TGF-β1/H2O2/HOCl to enhance the tumorigenicity of H... DisGeNET Detail
ZEB2 promotes vasculogenic mimicry by TGF-β1 induced epithelial-to-mesenchymal transition in hepatoc... DisGeNET Detail
TGF-β1 polymorphism 509 C>T is associated with an increased risk for hepatocellular carcinoma in HCV... DisGeNET Detail
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Association of Transforming Growth Factor Beta-1 (TGF-β1) Genetic Variation with Type 2 Diabetes and... DisGeNET Detail
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Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patients with Marfan syndro... DisGeNET Detail
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Following an oral treatment of 10 days, Icariin significantly attenuated Aβ deposition, microglial a... DisGeNET Detail
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Real-time polymerase chain reaction analysis confirmed the significant upregulation of interleukin (... DisGeNET Detail
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In the TNBC group, metastasis and poor response to treatment were significantly associated with VEGF... DisGeNET Detail
Similarly, tsTGF-β1 levels were elevated in MFS (P = 0.003) and in BAVD (P = 0.006) vs patients with... DisGeNET Detail
Confocal microscopy analysis showed a higher colocalization of latency associated peptide and latent... DisGeNET Detail
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Assessment of the frequency of the transforming growth factor beta-1 sequence polymorphisms in patie... DisGeNET Detail
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An impairment of the transforming growth factor-β1 (TGF-β1) signaling pathway has been demonstrated ... DisGeNET Detail
Icariin ameliorates neuropathological changes, TGF-β1 accumulation and behavioral deficits in a mous... DisGeNET Detail
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Confirmed BC risk SNPs rs17468277 (CASP8), rs1982073 (TGFB1), rs2981582 (FGFR2), rs13281615 (8q24), ... DisGeNET Detail
Confirmed BC risk SNPs rs17468277 (CASP8), rs1982073 (TGFB1), rs2981582 (FGFR2), rs13281615 (8q24), ... DisGeNET Detail
Here, we show that expression of the transcription factor Basonuclin-1 (Bnc1) modulates TGF-β1-induc... DisGeNET Detail
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Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... DisGeNET Detail
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In conclusion, the TT genotype of TGFβ1 T869C was associated with RA risk in the overall population ... DisGeNET Detail
Western blotting revealed the expression of C/EBPβ-LAP and -LIP in RA-FLS. DisGeNET Detail
MTHFR, TGFβ1, and TNFB polymorphisms don't appear to be clinically useful genetic markers for predic... DisGeNET Detail
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Identification and association of the single nucleotide polymorphisms, C-509T, C+466T and T+869C, of... DisGeNET Detail
We highlight TGF-β1 as a potential future therapeutic target in severe asthma including its importan... DisGeNET Detail
Association of transforming growth factor-Beta 1 promoter variant -509 c/t with bronchial asthma in ... DisGeNET Detail
In conclusion, these results suggest a role of TGF-β1 in olive-pollen sensitization and TNF-α and IL... DisGeNET Detail
Studies in vitro and in vivo using TGF-β1 and TGFB1I1 shRNA demonstrated that TGFB1I1 is required fo... DisGeNET Detail
Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... DisGeNET Detail
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Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and increased expression of ... DisGeNET Detail
Altered gene expression profile after exposure to transforming growth factor β1 in the 253J human bl... DisGeNET Detail
Evaluation of transforming growth factor-β1 suppress Pokemon/epithelial-mesenchymal transition expre... DisGeNET Detail
MiR-133 modulates TGF-β1-induced bladder smooth muscle cell hypertrophic and fibrotic response: impl... DisGeNET Detail
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Accordingly, in this manuscript, we demonstrate that the inhibition of GD3S using small hairpin RNA ... DisGeNET Detail
Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promotes tumor invasion a... DisGeNET Detail
No association of the TGF-β1 29T/C polymorphism with breast cancer risk in Caucasian and Asian popul... DisGeNET Detail
Activating transcription factor (ATF-3) is a stress response gene and is induced by transforming gro... DisGeNET Detail
Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-a... DisGeNET Detail
These findings establish the first link between HMGA1 and TGF-β1 in breast cancer, providing further... DisGeNET Detail
Two polymorphisms in the TGF-β1 gene (-509C/T and 869T/C) were described to influence susceptibility... DisGeNET Detail
HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epith... DisGeNET Detail
Increased VEGF-A, IGF-I, IGF-IR and TGF-β1 expressions were detected in breast cancer. DisGeNET Detail
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TGFβ1 genetic variants are associated with an increased risk of acute brucellosis. DisGeNET Detail
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Plasma levels of TGF-β1 may be a marker for predicting response to EGFR-TKIs and survival time in NS... DisGeNET Detail
Transforming growth factor-β1-induced epithelial to mesenchymal transition increases mitochondrial c... DisGeNET Detail
FOXM1 regulated by ERK pathway mediates TGF-β1-induced EMT in NSCLC. DisGeNET Detail
After stimulating with TGF-β1, almost all A549 cells and Luca 1 cells (Non-small-cell lung cancer pr... DisGeNET Detail
Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Pro... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs17886084 dbSNP
Genome
hg38
Position
chr19:41,330,323-41,353,922
Variant Type
snv
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