Uterine Fibroids

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Information
Disease name
Uterine Fibroids
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04126824 Active, not recruiting Early Phase 1 Effect of Addition of Steroids on Duration of Analgesia January 6, 2022 February 2026
NCT03271489 Active, not recruiting Phase 3 Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women January 4, 2017 July 11, 2024
NCT03194646 Active, not recruiting Phase 3 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids June 30, 2017 June 30, 2024
NCT02100904 Active, not recruiting Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry May 2014 September 2025
NCT00156208 Completed Phase 3 Safety of Treatment of Uterine Fibroids With Asoprisnil April 2004 December 2006
NCT00159328 Completed Phase 4 Efficacy Study of Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Large Fibroids March 2003 December 2006
NCT00067249 Completed Women's Use of Alternative Medicine: A Multiethnic Study April 2001 September 2001
NCT00166270 Completed N/A MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids January 2005 January 2009
NCT04177693 Completed Phase 1 Pharmacokinetics and Hepatic Safety of EGCG November 24, 2020 January 31, 2022
NCT04091529 Completed N/A Tailored Radiofrequency Ablation of Uterine Myomas March 1, 2017 March 31, 2019
NCT00295217 Completed Phase 3 MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation February 2006 October 2006
NCT00339547 Completed Risk Factors for Uterine Fibroids: A Case Control Study November 1, 1995 July 23, 2019
NCT00354471 Completed Uterine Artery Embolization for Symptomatic Fibroids
NCT00365989 Completed Phase 3 MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication October 2006 August 2008
NCT03886220 Completed Phase 4 A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women April 12, 2019 April 28, 2021
NCT03751124 Completed Phase 3 Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids October 16, 2018 November 18, 2021
NCT00579475 Completed Phase 1 The Effect of Mifepristone on Uterine Fibroids and Breast Tissue November 2004 June 2007
NCT03411980 Completed Phase 1 Pharmacokinetics and Safety of Vilaprisan in Renal Impairment February 2, 2018 February 6, 2019
NCT00628901 Completed Phase 4 A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) January 2006 January 2011
NCT03317795 Completed Phase 4 Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids November 14, 2017 December 28, 2020
NCT00712595 Completed Phase 2/Phase 3 Mifepristone for Treatment of Uterine Fibroids January 2007 March 2009
NCT00731341 Completed N/A Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata July 2008 February 2009
NCT03070951 Completed Phase 3 Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids May 23, 2017 October 4, 2020
NCT03070899 Completed Phase 3 Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids April 20, 2017 April 12, 2021
NCT00776074 Completed Phase 2 A Pharmacodynamic Study of Leuprorelin Gelatin-Free Formulation in Female Subjects With Uterine Fibroids. June 2006 July 2007
NCT02925494 Completed Phase 3 An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids September 14, 2016 March 22, 2019
NCT00837161 Completed Phase 1/Phase 2 Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids January 2009 December 2010
NCT02844920 Completed Evaluation of Uterine Patency Following Sonography-guided Transcervical Ablation of Fibroids July 20, 2017 August 27, 2018
NCT02835391 Completed N/A PerClot Compared to Usual Care in Gynaecology Procedures November 2015 August 2017
NCT00874029 Completed N/A Laparoscopic Radiofrequency Ablation (RFA) of Symptomatic Uterine Fibroids March 2009 March 2014
NCT02831556 Completed Point of Care 3D Ultrasound for Various Applications: A Pilot Study July 2016 August 31, 2022
NCT00882258 Completed Phase 2 Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids March 2006 March 2007
NCT00886873 Completed Phase 2/Phase 3 Mifepristone 10 or 5 mg for 6 Months to Treat Uterine Fibroids May 2008 May 2009
NCT00897897 Completed N/A Therapeutic Magnetic Resonance Imaging (MRI)-Guided High Intensity Focused Ultrasound (HIFU) Ablation of Uterine Fibroids April 2009 December 2009
NCT00958334 Completed Phase 2 Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003 September 7, 2006 October 15, 2008
NCT02819609 Completed Comparing Patient-Centered Outcomes After Treatment for Uterine Fibroids November 2014 January 2015
NCT00979342 Completed N/A Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System November 2009 July 2010
NCT00995878 Completed Phase 4 The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids. April 29, 2010 December 2017
NCT02691494 Completed Phase 3 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study) February 3, 2016 January 23, 2019
NCT01092988 Completed N/A A Clinical Study to Evaluate Safety of the ExAblate 2100 UF V2 System in the Treatment of Symptomatic Uterine Fibroids March 2010 February 2012
NCT02655237 Completed Phase 3 A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids March 5, 2016 September 25, 2017
NCT01142791 Completed N/A Safety Study of ExAblate for the Treatment of Uterine Fibroids May 2010 April 2012
NCT01152112 Completed N/A HOME Study: Hysteroscopic Office Myomectomy Evaluation June 2010 June 2013
NCT01156857 Completed Phase 3 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata July 2010 February 2012
NCT02655224 Completed Phase 3 A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids March 26, 2016 May 19, 2017
NCT01229826 Completed Magnetic Resonance Elastography (MRE) of Uterine Fibroids October 2010 June 2015
NCT01252069 Completed Phase 3 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata (PEARLIII-extension Study) January 2011 January 2014
NCT01285960 Completed N/A ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids May 2012 April 2016
NCT02654054 Completed Phase 3 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women December 22, 2015 December 12, 2018
NCT01369758 Completed N/A MyoSure Hysteroscopic Tissue Removal System Registry Study November 2010 May 2013
NCT01377519 Completed N/A Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids June 2011 December 2012
NCT01388907 Completed Phase 4 Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery May 2006 June 2011
NCT01441635 Completed Phase 2 Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids September 8, 2011 May 17, 2014
NCT01451424 Completed Phase 2 Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids February 2012 January 2013
NCT01452659 Completed Phase 2 Efficacy and Safety of TAK-385 in the Treatment of Uterine Fibroids October 2011 September 2012
NCT02472184 Completed N/A Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy October 2015 March 2017
NCT02470741 Completed Phase 4 Pilot of Letrozole for Uterine Myomas July 2015 December 2017
NCT02323646 Completed Phase 2 Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids February 12, 2015 April 6, 2017
NCT01563783 Completed N/A Post Market TRUST Study December 2012 June 2022
NCT01588899 Completed N/A China Clinical Trial for Therapeutic MR-HIFU Ablation of Uterine Fibroids May 2012 May 2015
NCT01629563 Completed Phase 3 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata June 2012 January 2015
NCT01631903 Completed Phase 2 Extension of Study ZPV-200 September 2012 April 2014
NCT02301897 Completed Phase 2 A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids March 16, 2015 June 2, 2017
NCT01642472 Completed Phase 3 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata July 2012 April 2015
NCT02192606 Completed N/A Does 3D Laparoscopy Improve Vaginal Cuff Suture Time? November 2013 September 2016
NCT01739621 Completed Phase 2 Safety, Pharmacokinetics and Efficacy of Proellex® (Telapristone Acetate) Administered Vaginally in the Treatment of Premenopausal Women With Uterine Fibroids Who Have Completed ZPV-200 September 2012 April 2014
NCT01750008 Completed N/A Laparoscopic Uterine Sparing Techniques Outcomes and Reinterventions November 2012 June 2018
NCT01817530 Completed Phase 2 Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF) April 8, 2013 December 2015
NCT02086370 Completed N/A Prophylactic Salpingectomy for the Prevention of the Ovarian Cancer: Comparison Between Surgical Techniques March 2014 April 2015
NCT01840124 Completed N/A Uterine Leiomyoma Treatment With Radiofrequency Ablation July 2013 January 2020
NCT02086279 Completed N/A AMH Levels Change During Treatment With GnRh Agonist March 2014 November 2014
NCT01852734 Completed N/A Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives November 2013 April 2016
NCT01865929 Completed N/A Minimally Invasive Benign Hysterectomy January 2010 June 2013
NCT01936493 Completed Biologic Predictors of Leiomyoma Treatment Outcomes August 2009 May 26, 2015
NCT01992718 Completed Early Phase 1 What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography November 2013 March 2018
NCT02059954 Completed N/A Vaginal vs. Laparoscopic Hysterectomy January 2014 September 2017
NCT00150644 Completed Phase 2 A Study to Evaluate the Effects of Asoprisnil(J867) in Women With Uterine Fibroids Who Are Scheduled for a Hysterectomy July 2003 May 2005
NCT00152256 Completed Phase 3 A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids September 2003 February 2005
NCT00156156 Completed Phase 3 Study of Asoprisnil in the Treatment of Uterine Fibroids. November 2004 February 2007
NCT06055114 Not yet recruiting Study on Vaginal Microecology and Cervical Local Immune Function in Patients With Uterine Fibroids of Childbearing Age October 9, 2023 October 9, 2026
NCT05448365 Recruiting Phase 3 Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid July 1, 2022 October 1, 2025
NCT05078307 Recruiting N/A Evaluation of a Hysteroscopic Method With Vaporization in the Hysteroscopic Treatment of Submucosal Uterine Fibroids September 25, 2021 May 17, 2024
NCT05862272 Recruiting Phase 3 A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis August 14, 2023 September 2030
NCT02914704 Recruiting N/A Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU) January 2016 December 2025
NCT05620355 Recruiting Phase 3 Efficacy and Safety of BG2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids. December 16, 2022 March 2025
NCT03948789 Recruiting Phase 3 Phase III Study of MR-Guided Focused Ultrasound Surgery for the Treatment of Uterine Fibroids Compared to Myomectomy July 15, 2020 June 2025
NCT00496067 Terminated N/A Uterine Artery Occlusion for Fibroid Related Bleeding April 2007 December 2009
NCT01834703 Terminated N/A Uterine Artery Embolization(UAE) Versus High-Intensity-Focused-Ultrasound(HIFU) for Treatment of Uterine Fibroids May 2009 December 2015
NCT00232713 Terminated Uterine Fibroid Pregnancy Registry December 2005 December 2005
NCT05026502 Terminated A Study to Assess Patient-Reported Quality of Life and Effectiveness on Control of Bleeding in Adult Participants With Heavy Menstrual Bleeding Due to Uterine Fibroids Taking Oral Oriahnn Capsules October 5, 2021 August 30, 2022
NCT01539187 Terminated N/A Fibroid Ablation Study - Large Fibroids June 2012 June 2014
NCT01504308 Terminated Phase 2/Phase 3 Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids May 2012 March 2016
NCT01226290 Terminated N/A Fibroid Ablation Study January 2011 March 2014
NCT01140555 Terminated N/A A Pilot Study to Determine Optimal Procedure Steps to Obtain and Maintain Uterine Artery Occlusion With the D-UAO Device April 2010 July 2010
NCT01069120 Terminated Phase 3 Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids April 2009 August 2009
NCT01786226 Terminated Phase 2/Phase 3 Mifepristone to Treat Uterine Fibroids March 2010 March 2012
NCT02811159 Terminated Phase 2 An Extension Study of 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids July 26, 2016 May 4, 2017
NCT00958893 Terminated Phase 2 An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have Previously Completed ZPU 003 Ext June 2008 August 2009
NCT01675011 Terminated N/A Embozene Microspheres for Uterine Fibroid Embolization (UFE) August 2012 December 2013
NCT00853567 Terminated Phase 3 Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic Uterine Fibroids February 2009 August 2009
NCT01842789 Terminated N/A Post Market Evaluation of Acessa With TAG April 2013 February 2016
NCT00785356 Terminated Phase 3 Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine Fibroids October 2008 August 2009
NCT01998854 Terminated Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated With VizAblate® Intrauterine-ultrasound Guided RF Ablation February 2013 January 2015
NCT00737282 Terminated Phase 3 Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids October 2008 August 2009
NCT00735553 Terminated Phase 3 Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids August 2008 August 2009
NCT03240523 Terminated Phase 3 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids July 31, 2017 October 25, 2021
NCT00702702 Terminated Phase 3 Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids June 2008 August 2009
NCT03400943 Terminated Phase 3 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3) January 17, 2018 April 6, 2022
NCT00683917 Terminated Phase 2 Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids May 2008 August 2009
NCT03400956 Terminated Phase 3 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4) January 24, 2018 June 30, 2021
NCT00584207 Terminated Early Phase 1 Radiofrequency Ablation of Uterine Fibroids March 2004 July 2008
NCT01555073 Terminated Phase 4 Preemptive Analgesia Following Uterine Artery Embolization October 2011 October 2013
NCT02425878 Terminated Phase 3 Ulipristal Acetate 10 mg and Asisted Reproduction October 19, 2015 May 31, 2016
NCT00496080 Terminated N/A Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related Bleeding June 2007 October 2010
NCT00163930 Unknown status Post-Operative Pain Management in Patients Undergoing Uterine Artery Embolisation for Symptomatic Leiomyomata January 2005 December 2007
NCT02086344 Unknown status N/A Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy February 2014 December 2016
NCT02283502 Unknown status Phase 1 Clinical Test of the MRgHIFU System on Uterine Fibroids September 2014 May 2015
NCT01635452 Unknown status A Prospective Multicenter Non-interventional Study of Women Treated With ESMYA (Ulipristal Acetate) as Pre-operative Treatment of Moderate to Severe Symptoms of Uterine Fibroids May 2012 March 2016
NCT02440750 Unknown status Phase 4 Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women June 2016 June 2017
NCT02748460 Unknown status Non-interventional Study to Evaluate Long Term Safety, Prescription Management Patterns of Esmya in a Long Term Setting December 2015 December 2022
NCT00860002 Unknown status The Benefits and Limits of Laparoscopic Surgery for Uterine Fibroids January 2009 December 2014
NCT02884960 Unknown status N/A Safety and Efficacy of Embozene Microspheres for Uterine Fibroid Embolization October 2016 October 2018
NCT02942537 Unknown status Phase 2/Phase 3 Study of Volume Reduction of Uterine Fibroids After Embolization or Microwave Treatment January 23, 2017 February 2020
NCT03500367 Unknown status Phase 4 Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis January 1, 2018 December 31, 2022
NCT03586947 Unknown status N/A Association Between Vitamin D and the Risk of Uterine Fibroids September 15, 2018 July 1, 2021
NCT00277680 Unknown status N/A Laparoscopic Occlusion of Uterine Vessels Compared to Uterine Fibroid Embolization for Treatment of Uterine Fibroids December 2000 April 2010
NCT04400942 Unknown status Predictive Factors for Complete Myoma Resection During Hysteroscopic Myomectomy January 1, 2015 December 1, 2021
NCT04567095 Withdrawn A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization Measures Among Patients in Canada October 31, 2020 June 30, 2021
NCT04567589 Withdrawn A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization Measures Among Healthcare Professionals in Canada September 30, 2020 February 28, 2021
NCT00180739 Withdrawn Phase 4 Safety Trial of Magnetic Resonance (MR) Guided Focused Ultrasound Surgery (FUS) in Women With Uterine Fibroids Wishing to Pursue Pregnancy in the Future April 2004 August 2005
NCT03699176 Withdrawn Phase 3 Assessment of Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids October 27, 2018 December 25, 2019
NCT00768742 Withdrawn N/A Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study September 2008 November 2010
NCT00874302 Withdrawn Phase 3 Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms
NCT01328067 Withdrawn N/A Study to Evaluate the Safety and Effectiveness of MRgFUS Compared With Myomectomy for the Treatment of Uterine Fibroids June 2011 June 2017
NCT01971060 Withdrawn N/A a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy. August 2013 October 2014