bronchiectasis
Information
- Disease name
- bronchiectasis
- Disease ID
- DOID:9563
- Description
- "A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances." [url:http\://www.merck.com/mmhe/sec04/ch047/ch047a.html, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=bronchiectasis]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| CFTR | 7 | 117,480,025 | 117,668,665 | 12 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06002334 | Active, not recruiting | Relationship Between Nutritional State and Respiratory Muscle Weakness in Adult Patients With Bronchietasis | February 23, 2023 | June 15, 2024 | |
| NCT02804971 | Active, not recruiting | Cardiovascular Comorbidities and Bronchiectasis | October 25, 2016 | December 2023 | |
| NCT06106789 | Active, not recruiting | A Study of the Clinical Benefit of Tobramycin Inhalation Solution | January 1, 2021 | April 30, 2024 | |
| NCT04616924 | Active, not recruiting | Phase 3 | RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease | December 1, 2020 | December 2024 |
| NCT05344300 | Active, not recruiting | Temperature Recording in Lungs of Volunteers With and Without Pulmonary Diseases | September 1, 2022 | September 2025 | |
| NCT02514226 | Active, not recruiting | N/A | Evaluation of Periodontal Treatment in Patients With Bronchiectasis | August 2015 | December 2024 |
| NCT00522314 | Completed | N/A | Airway Clearance in Bronchiectasis: is Non-Invasive Ventilation a Useful Adjunct in Moderate to Severe Disease? | October 2003 | April 2006 |
| NCT00656565 | Completed | Inspiratory Flow and Volumes in Bronchiectatics | June 2008 | July 2008 | |
| NCT00656721 | Completed | N/A | Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients | September 2004 | June 2006 |
| NCT00669331 | Completed | Phase 3 | Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis | November 2009 | January 2014 |
| NCT00697177 | Completed | The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease | July 2005 | June 2009 | |
| NCT00728715 | Completed | N/A | Efficacy of Budesonide-Formoterol in Bronchiectasis | January 2004 | January 2005 |
| NCT00730977 | Completed | Phase 1/Phase 2 | A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device | August 2008 | September 2008 |
| NCT00749866 | Completed | Phase 4 | Long Term Nebulised Gentamicin in Patients With Bronchiectasis | May 2007 | August 2009 |
| NCT00769119 | Completed | Phase 2 | A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis | September 2008 | April 2009 |
| NCT00775138 | Completed | Phase 2 | Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infection Due to Pseudomonas Aeruginosa. | June 24, 2008 | May 11, 2009 |
| NCT00805025 | Completed | Phase 2 | Evaluation of the Quality of Life Questionnaire-Bronchiectasis (QOL-B) in Patients With Bronchiectasis | December 2008 | October 2009 |
| NCT00816309 | Completed | Phase 4 | Is Regular Chest Physiotherapy an Effective Treatment in Severe, Non Cystic Fibrosis Bronchiectasis? | October 2007 | March 2009 |
| NCT00868075 | Completed | Phase 4 | Pulmonary Rehabilitation in Non Cystic Fibrosis Bronchiectasis | March 2009 | August 2011 |
| NCT00885521 | Completed | Phase 1 | Exercise Training in Patients With Non-cystic Fibrosis (CF) Bronchiectasis | February 2009 | February 2013 |
| NCT00930982 | Completed | Phase 2 | Evaluation of Cipro Inhale in Patients With Non-cystic Fibrosis Bronchiectasis | June 2009 | September 2010 |
| NCT00952718 | Completed | N/A | Effects of Inspiratory Muscle Training in Patients With Bronchiectasis | January 2008 | March 2009 |
| NCT01076491 | Completed | Phase 1/Phase 2 | High Dose Inhaled Mannitol Study | January 2009 | April 2009 |
| NCT01113034 | Completed | Phase 1 | A Safety Trial of DAS181 (Fludase®) in Adult Subjects With Well-Controlled Asthma or Bronchiectasis | July 2010 | August 22, 2011 |
| NCT01117493 | Completed | N/A | Expert Patient Self-management Programme Versus Usual Care in Bronchiectasis | September 2006 | October 2007 |
| NCT01196702 | Completed | Lymphocyte Immunophenotyping in Common Variable Immunodeficiency | September 1, 2020 | December 30, 2023 | |
| NCT01764841 | Completed | Phase 3 | Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) | May 2, 2013 | March 9, 2016 |
| NCT00129701 | Completed | N/A | Can we Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation | November 2003 | January 2006 |
| NCT00277537 | Completed | Phase 3 | Safety and Efficacy of Bronchitol in Bronchiectasis | March 2006 | July 2008 |
| NCT00415350 | Completed | Phase 3 | Bronchiectasis and Long Term Azithromycin Treatment | April 2008 | December 2010 |
| NCT00484263 | Completed | Phase 3 | The Long Term Effect of Inhaled Hypertonic Saline (6%) in Patients With Non Cystic Fibrosis Bronchiectasis | December 2007 | October 2009 |
| NCT00487149 | Completed | Respiratory Muscle Strength in Bronchiectasis: Repeatability and Reliability | October 2005 | July 2008 | |
| NCT01255592 | Completed | Phase 2 | Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis | February 2011 | February 2012 |
| NCT01270074 | Completed | Phase 3 | Prevention of Bronchiectasis in Infants With Cystic Fibrosis | April 2012 | March 2021 |
| NCT01299181 | Completed | Phase 4 | A Trial of Atorvastatin as an Anti-Inflammatory Agent in Non-Cystic Fibrosis Bronchiectasis | November 2010 | August 2013 |
| NCT01299194 | Completed | Phase 4 | Atorvastatin in Bronchiectasis in Patients With Pseudomonas Aeruginosa | November 2010 | May 2017 |
| NCT01300403 | Completed | N/A | Physiological Effects of Expiration With the Glottis Open in Lateral Posture (ELTGOL) and Flutter Valve in Patients With Bronchiectasis | June 2009 | August 2010 |
| NCT01313624 | Completed | Phase 3 | Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis | April 2011 | June 2013 |
| NCT01314716 | Completed | Phase 3 | Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis | April 2011 | July 2013 |
| NCT01463371 | Completed | N/A | Effects of Azithromycin on Airway Oxidative Stress Markers in Patients With Bronchiectasis | October 2006 | September 2007 |
| NCT01569009 | Completed | Physical Activity in Bronchiectasis | June 2012 | July 2013 | |
| NCT01578681 | Completed | N/A | ELTGOL and Bronchiectasis. Respiratory Therapy | September 2011 | March 2017 |
| NCT01615484 | Completed | N/A | Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability | September 2013 | January 2017 |
| NCT01684683 | Completed | Phase 4 | The Effect of Theophylline in the Treatment of Bronchiectasis | November 2012 | September 2014 |
| NCT00105183 | Completed | Phase 3 | EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection | January 2005 | January 2011 |
| NCT01769898 | Completed | Phase 4 | The Role of Theophylline Plus Low-dose Formoterol-budesonide in Treatment of Bronchiectasis | July 2013 | November 2014 |
| NCT01818544 | Completed | Phase 2 | Safety and Efficacy of Oral BAY85-8501 in Patients With Non-CF (Cystic Fibrosis) Bronchiectasis | April 2013 | June 2014 |
| NCT01854788 | Completed | N/A | 3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis | September 2010 | August 2012 |
| NCT01906047 | Completed | Impact of Chronic Air Pollution on Non-cystic Fibrosis Bronchiectasis | June 2006 | April 2013 | |
| NCT02035488 | Completed | Phase 1/Phase 2 | Pharmacokinetic Evaluation and Tolerability of Dry Powder Tobramycin by a Novel Device in Patients With Non Cystic Fibrosis Bronchiectasis | October 2013 | December 2014 |
| NCT02045394 | Completed | Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study | June 2013 | ||
| NCT02047773 | Completed | Phase 4 | Bacterial Load Guided Therapy for Severe Bronchiectasis Exacerbations | January 2014 | February 1, 2020 |
| NCT02048397 | Completed | N/A | Pulmonary Rehabilitation Program (PRP) Versus PRP Plus Nutritional Supplementation in Patients With Bronchiectasis | September 2013 | December 2014 |
| NCT02106832 | Completed | Phase 3 | Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) | April 30, 2014 | October 19, 2016 |
| NCT02107274 | Completed | Phase 4 | Efficacy of Azithromycin in Treatment of Bronchiectasis | November 2011 | December 2013 |
| NCT02208830 | Completed | N/A | Physical Capacity in Patients With Bronchiectasis Before and After Rehabilitation Program | January 2012 | July 2018 |
| NCT02282202 | Completed | N/A | Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD | September 2013 | September 2014 |
| NCT02324855 | Completed | N/A | Long-term Airway Clearance Therapy in Non-cystic Fibrosis Bronchiectasis | October 2015 | June 2020 |
| NCT02392663 | Completed | N/A | Sputum Clearance Effects of Hypertonic Saline in Non-cystic Fibrosis Bronchiectasis | March 2015 | January 2016 |
| NCT02411981 | Completed | N/A | Effects of Chest Physiotherapy (CPT) on Lung Clearance Index (LCI) in Non Cystic Fibrosis (CF) Bronchiectasis | April 2015 | February 2016 |
| NCT02458807 | Completed | The SENSOR Study: A Mixed-methods Study of SElf-management Checks to Predict exacerbatioNs of Pseudomonas Aeruginosa in Patients With Long-term reSpiratORy Conditions | August 18, 2014 | February 28, 2015 | |
| NCT02468271 | Completed | Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK | October 2015 | July 31, 2019 | |
| NCT02468908 | Completed | Phase 1 | Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects | May 2015 | October 2015 |
| NCT02491723 | Completed | N/A | Macrolide Mediates Pulmonary Infection of Pseudomonas Aeruginosa | January 2014 | January 2016 |
| NCT02509637 | Completed | N/A | Acute Effects of a Flutter Device and Chest Wall Compression on Respiratory System Impedance in Bronchiectasis Patients | August 2015 | September 2016 |
| NCT02550821 | Completed | Comparison of Physical Activity Level Between Patients With Bronchiectasis and Healthy Subjects | September 2015 | August 2016 | |
| NCT02563197 | Completed | Phase 1 | Inhalation Flow Rate-study | November 23, 2015 | April 29, 2016 |
| NCT02625246 | Completed | Phase 1 | Safety and Potential Efficacy of Human Mesenchymal Stem Cells in Non-Cystic Fibrosis Bronchiectasis | February 4, 2016 | May 15, 2019 |
| NCT02656992 | Completed | N/A | Effects of High Intensity Inspiratory Muscle Training on Exercise Capacity in Patients With Bronchiectasis | September 2014 | January 5, 2018 |
| NCT02661438 | Completed | N/A | Summative Usability Study of Ciprofloxacin Dry Powder for Inhalation Using Placebo | January 12, 2016 | March 17, 2016 |
| NCT02714283 | Completed | Comparative Effectiveness and Safety of Inhaled Corticosteroids and Antimicrobial Compounds for Non-CF Bronchiectasis | October 28, 2016 | July 1, 2018 | |
| NCT02731482 | Completed | N/A | Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis | June 2016 | August 2019 |
| NCT02782312 | Completed | Phase 4 | Salmeterol-Fluticasone Combined Inhaled Therapy for Non-cystic Fibrosis Bronchiectasis | June 2011 | June 2013 |
| NCT02859194 | Completed | N/A | The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients | May 31, 2016 | October 14, 2016 |
| NCT03058718 | Completed | N/A | Procalcitonin-Guided Antibiotic Therapy in Bronchiectasis | January 1, 2014 | February 1, 2017 |
| NCT03420209 | Completed | N/A | The Effect of Proprioceptive Neuromuscular Facilitation (PNF) Technique for Children With Chronic Pulmonary Diseases. | December 1, 2016 | August 1, 2022 |
| NCT03534986 | Completed | N/A | Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements | February 20, 2018 | March 16, 2018 |
| NCT03550417 | Completed | Evaluation of Medical and Nursing Management for Bronchiectasis | June 22, 2015 | March 28, 2023 | |
| NCT03628456 | Completed | N/A | Effect of HFCWO Vests on Spirometry Measurements | September 13, 2018 | July 2, 2019 |
| NCT03643263 | Completed | Exhaled Breath Condensate Assessment in Stable Non-Cystic Fibrotic Bronchiectasis | June 25, 2018 | July 2, 2020 | |
| NCT03655808 | Completed | Phase 1/Phase 2 | Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis | June 21, 2020 | May 17, 2023 |
| NCT03670940 | Completed | Bronchiectasis Effect in COPD Patients | January 2015 | April 2018 | |
| NCT03750734 | Completed | Target Validation and Discovery in Idiopathic Bronchiectasis | September 10, 2019 | August 9, 2021 | |
| NCT03883048 | Completed | Idiopathic Bronchiectasis and Pulmonary Hypertension | June 1, 2018 | December 31, 2021 | |
| NCT03920124 | Completed | N/A | Feasibility of Interval Exercise in Bronchiectasis | June 5, 2019 | September 5, 2019 |
| NCT03950531 | Completed | The Effect of Bronchiectasis on the Exacerbation and Mortality in COPD | January 25, 2010 | January 25, 2017 | |
| NCT04038892 | Completed | N/A | The Effect of Different Virtual Reality-Based Exercise Trainings on Pulmonary Function, Respiratory and Peripheral Muscle Strength, Functional Capacity and Balance in Children With Bronchiectasis | July 27, 2019 | February 6, 2021 |
| NCT04081740 | Completed | Biological Determinants of Sputum Rheology in Chronic Airway Diseases | September 15, 2019 | October 15, 2019 | |
| NCT04122547 | Completed | Phase 3 | Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis Bronchiectasis | January 2015 | December 2015 |
| NCT04153448 | Completed | Comparison of Sit-to-stand Test With Six-minute Walk Test in Bronchiectasis and Healthy Children | December 23, 2019 | January 30, 2020 | |
| NCT04170114 | Completed | N/A | Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis | January 1, 2020 | November 1, 2020 |
| NCT04271969 | Completed | Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population | February 18, 2020 | December 1, 2023 | |
| NCT04487873 | Completed | COVID-19 Phobia in Patients With Bronchiectasis During Covid-19 Pandemic | July 23, 2020 | January 31, 2021 | |
| NCT04765033 | Completed | Phase 4 | Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD. | February 4, 2021 | August 28, 2023 |
| NCT04857814 | Completed | N/A | Integrating Electronic Patient Reported Biometric Measures (ePReBMs) From Wearable Devices in Respiratory Diseases | July 1, 2021 | March 1, 2023 |
| NCT04885790 | Completed | Investigation of Dynamic Hyperinflation and Its Relationship With Functional Exercise Capacity in Children With Bronchiectasis | June 1, 2021 | August 10, 2021 | |
| NCT04939558 | Completed | Cardiorespiratory Diagnostic Study | June 2, 2021 | November 30, 2022 | |
| NCT05034900 | Completed | N/A | Does Addition of Oscillatory Positive Expiratory Pressure (OPEP) Device to a Chest Physiotherapy Program Provide Further Health Benefits in Children With Bronchiectasis? | September 6, 2021 | September 15, 2022 |
| NCT05084547 | Completed | Comparison of Upper Extremity Exercise Capacity and ADL Between Subjects With Bronchiectasis and Healthy Controls | January 22, 2020 | December 22, 2022 | |
| NCT05238675 | Completed | Phase 2 | A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis | March 21, 2022 | May 30, 2024 |
| NCT05408455 | Completed | N/A | Expiratory Muscle Training in Bronchiectasis | February 1, 2021 | January 23, 2023 |
| NCT05553119 | Completed | A Study of Home-based Pulmonary Rehabilitation and Health Coaching to Treat Bronchiectasis | August 25, 2022 | July 30, 2023 | |
| NCT06175039 | Completed | N/A | Telerehabilitation in Patients With Bronchiectasis | May 15, 2023 | June 4, 2024 |
| NCT06457269 | Completed | N/A | Evaluating the Potential of Large Language Models for Respiratory Disease Consultations | October 1, 2023 | April 4, 2024 |
| NCT05751538 | Not yet recruiting | Artificial Intelligence in Computed Tomography for Quantifying Lung Changes of Bronchiectasis Patients | March 1, 2023 | December 30, 2023 | |
| NCT05681364 | Not yet recruiting | Prediction of Pulmonary Rehabilitation Outcomes in Patients With Chronic Respiratory Disease Based on Metabolomics: a Prospective Cohort Study | April 2023 | December 2024 | |
| NCT06344000 | Not yet recruiting | Study on Disease Progression and Nutritional Status in Bronchiectasis | April 15, 2024 | April 15, 2027 | |
| NCT06368804 | Not yet recruiting | Phase 2 | Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis | June 1, 2024 | June 1, 2028 |
| NCT06346938 | Not yet recruiting | The Clinical Significance of CT-based Biomarkers in the Classification and Prognosis of Bronchiectasis | March 26, 2024 | March 26, 2027 | |
| NCT05174741 | Not yet recruiting | N/A | Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients. | April 2023 | February 2024 |
| NCT06326957 | Not yet recruiting | N/A | Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE) | May 2024 | July 2028 |
| NCT06409299 | Not yet recruiting | Phase 3 | Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention | September 1, 2024 | August 31, 2027 |
| NCT06164093 | Not yet recruiting | N/A | Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis | November 30, 2023 | June 1, 2024 |
| NCT06035055 | Not yet recruiting | Phase 4 | Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis | October 2023 | January 2024 |
| NCT06280391 | Recruiting | Phase 2 | A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis | February 20, 2024 | August 11, 2026 |
| NCT05407792 | Recruiting | N/A | Efficacy and Safety of Long-term Oral Staphylococcus Albicans Tablets in Patients With Bronchiectasis | June 6, 2022 | July 1, 2024 |
| NCT03120481 | Recruiting | Controls for Respiratory Diseases | April 10, 2017 | February 28, 2037 | |
| NCT06361121 | Recruiting | N/A | Mid-point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block in Posterolateral Thoracotomy | March 1, 2024 | March 2025 |
| NCT03455686 | Recruiting | N/A | Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease | April 19, 2018 | December 2024 |
| NCT05572346 | Recruiting | Digital App for Telerehabilitation in Respiratory Diseases | October 17, 2022 | January 2024 | |
| NCT03561818 | Recruiting | N/A | Comparison of PR Efficiency in Home-based With Hospital-based PR in Bronchiectasis | June 19, 2018 | December 30, 2024 |
| NCT05731427 | Recruiting | Research on the Mechanism Affecting Progression of Bronchiectasis | February 1, 2021 | February 1, 2026 | |
| NCT03643653 | Recruiting | The Establishment of China Bronchiectasis Registry and Research Collaboration | January 1, 2019 | December 2025 | |
| NCT05741697 | Recruiting | HFNC in Management of Bronchiectasis Exacerbation | March 1, 2023 | December 1, 2023 | |
| NCT05783869 | Recruiting | Study of Bronchiectasis and Associated Cardiovascular Comorbidities | March 25, 2023 | November 1, 2023 | |
| NCT05838144 | Recruiting | N/A | Efficacy of Acapella on Spirometry Measures in Patients With Bronchiectasis | August 1, 2023 | October 20, 2023 |
| NCT05846230 | Recruiting | Phase 2 | Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine | July 21, 2023 | March 30, 2026 |
| NCT05865886 | Recruiting | Phase 2 | A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™) | January 31, 2024 | October 24, 2024 |
| NCT05932316 | Recruiting | N/A | Evaluating Bronchodilator Response in Patients With Bronchiectasis | May 20, 2023 | December 2024 |
| NCT04140214 | Recruiting | Phase 3 | Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR) | June 27, 2018 | September 30, 2024 |
| NCT06144996 | Recruiting | Development of a Canadian Bronchiectasis and NTM Database | January 1, 2023 | January 2050 | |
| NCT06160713 | Recruiting | Phase 3 | Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations | December 1, 2023 | January 31, 2026 |
| NCT00943514 | Recruiting | Natural History of Bronchiectasis | August 1, 2009 | ||
| NCT06166056 | Recruiting | Phase 1/Phase 2 | A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis | November 29, 2023 | June 2025 |
| NCT02279329 | Recruiting | N/A | Longitudinal Study of Helium-3 and Xenon-129 Magnetic Resonance Imaging | May 2009 | February 2025 |
| NCT06242795 | Recruiting | Phase 4 | Hypertonic Saline in NCFB | April 2024 | June 2025 |
| NCT02527486 | Recruiting | Seoul National University Airway Registry | September 2011 | December 2031 | |
| NCT05112055 | Recruiting | Microbiology and Treatment Outcome of Acute Exacerbation of Bronchiectasis in Hong Kong | December 2, 2021 | December 1, 2025 | |
| NCT02748798 | Recruiting | Early Phase 1 | Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders | November 10, 2020 | December 22, 2023 |
| NCT02779478 | Recruiting | Evaluation Of The Lung Microbiome In NTM Bronchiectasis | October 1, 2014 | July 2026 | |
| NCT05351242 | Recruiting | N/A | Thermotherapy Against Persistent Bacterial LUNG Infections | January 31, 2023 | September 2026 |
| NCT04843345 | Suspended | Sjogren's Lung Study | April 1, 2021 | April 1, 2030 | |
| NCT04266873 | Suspended | N/A | Feasibility Study of the AffloVest in Bronchiectasis | February 1, 2020 | December 31, 2023 |
| NCT04396366 | Terminated | Phase 2 | Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis | February 2, 2021 | June 21, 2023 |
| NCT03262064 | Terminated | Different Phenotypes of Bronchiectasis | July 1, 2017 | January 1, 2019 | |
| NCT01209546 | Terminated | Phase 1 | Study of the Effect of FLUTTER® VRP1 (PEP and Oscillating High Frequency). | July 2007 | December 2010 |
| NCT03262142 | Terminated | Phase 4 | Targeted AntiBiotics for Chronic Pulmonary Diseases | January 10, 2018 | March 1, 2023 |
| NCT01241942 | Terminated | N/A | Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability | December 2010 | March 2013 |
| NCT02058407 | Terminated | Phase 1 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects | January 28, 2014 | October 31, 2014 |
| NCT04858451 | Terminated | Phase 2 | COmmunity Patients at Risk of Viral Infections Including SARS-CoV-2 | March 1, 2021 | February 8, 2023 |
| NCT02096315 | Terminated | Phase 2 | Safety, Efficacy and PK/PD of POL7080 in Patients With Exacerbation of Non-cystic Fibrosis Bronchiectasis. | December 2013 | November 2015 |
| NCT00452114 | Terminated | N/A | In-exsufflator Cough Assist Device in Patients With Symptomatic Bronchiectasis | April 2004 | May 2008 |
| NCT03846570 | Terminated | Phase 3 | Formoterol-beclomethasone in Patients With Bronchiectasis: a Randomized Controlled Trial | January 29, 2019 | July 5, 2022 |
| NCT03745196 | Terminated | Phase 2 | The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases | November 15, 2018 | June 1, 2020 |
| NCT00524095 | Terminated | Phase 2 | Bronchiectasis in Chronic Obstructive Pulmonary Disease (COPD) Patients: Role of Prophylaxis | September 2006 | February 2009 |
| NCT02179983 | Terminated | N/A | Tayside Rehabilitation in Bronchiectasis Exacerbations (TRIBE) : a Randomized Controlled Trial | June 2014 | June 2018 |
| NCT02598999 | Terminated | Phase 1 | Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients | November 2015 | December 2021 |
| NCT02950116 | Terminated | N/A | Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease | March 9, 2017 | April 7, 2017 |
| NCT04490447 | Unknown status | Identification of Microbiome and Metabolome of Bronchiectasis in Chinese Population. | August 1, 2019 | September 1, 2021 | |
| NCT04601792 | Unknown status | Phase 4 | A Series of N-of-1 Trials of Traditional Chinese Medicine Based on Bayesian Method | December 1, 2019 | December 31, 2022 |
| NCT02722642 | Unknown status | Phase 1/Phase 2 | Autologous Bronchial Basal Cells Transplantation for Treatment of Bronchiectasis | March 2016 | June 2020 |
| NCT02163642 | Unknown status | Role of Innate Immunity in Non-Cystic Fibrosis Bronchiectasis | April 2014 | April 2018 | |
| NCT05300347 | Unknown status | Observational Study Evaluating the Prevalence of Enzyme Deficiency in Pulmonology Clinics (ADA) | June 17, 2021 | June 17, 2023 | |
| NCT01112410 | Unknown status | Phase 2 | Hypertonic Saline (6%) Versus Isotonic Saline (0.9%) in Bronchiectasis | January 2010 | August 2010 |
| NCT04803695 | Unknown status | Role of Pseudomonas Aeruginosa Biofilms in Exacerbations in Patients With Bronchiectasis With and Without Chronic Obstructive Pulmonary Disease | March 1, 2018 | December 1, 2021 | |
| NCT02315547 | Unknown status | N/A | Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis | January 2015 | December 2023 |
| NCT03147651 | Unknown status | Exercise Capacity in Patients With Cystic Fibrosis vs. Non-cystic Fibrosis Bronchiectasis | October 2015 | December 2017 | |
| NCT02765295 | Unknown status | N/A | Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis: A Randomized, Multi-center, Double-blind Study | June 1, 2016 | December 2021 |
| NCT04905992 | Unknown status | N/A | Is a Single Daily Session Combining HS + Physio Sufficient to Obtain Long-term Clinical Benefits in Bronchiectasis? | July 1, 2021 | December 2023 |
| NCT02906826 | Unknown status | N/A | Adherence to Airway Clearance. Novel Approaches to Improving Adherence | August 2016 | September 2017 |
| NCT04966793 | Unknown status | Microbial Colonization Distribution and Adaptive Evolution of Lower Respiratory Tract in Bronchiectasis Patients. | February 20, 2020 | January 31, 2023 | |
| NCT02507843 | Unknown status | Phase 4 | Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis | January 2015 | June 2017 |
| NCT02509091 | Unknown status | Phase 4 | Therapy of Bronchoalveolar Lavage and Local Amikacin Injection in Patients With Acute Exacerbation of Bronchiectasis | December 2014 | June 2019 |
| NCT03147443 | Unknown status | Phase 4 | Evaluating the Effects of Traditional Chinese Medicine by N-of-1 Trials | March 1, 2017 | December 31, 2019 |
| NCT03443531 | Unknown status | Phase 3 | Effects of Traditional Chinese Medicine on Bronchiectasis Patients | March 2018 | December 2020 |
| NCT02823587 | Unknown status | N/A | Pulmonary Rehabilitation in Non-Cystic Fibrosis Bronchiectasis | July 2016 | December 2019 |
| NCT03594032 | Unknown status | Prevalence and Characteristics of Patients With Bronchiectasis Comorbid Nontuberculous Mycobacteria | August 14, 2018 | August 2021 | |
| NCT03638063 | Unknown status | ATP and Capsaicin Cough Provocation Test in Chronic Cough and Bronchiectasis | October 29, 2018 | July 2020 | |
| NCT02546297 | Unknown status | Phase 4 | Comparisons of Inhaled LAMA or LAMA+LABA or ICS+LABA for COPD With Bronchiectasis | September 15, 2017 | March 1, 2021 |
| NCT03013452 | Unknown status | N/A | Oscillating PEP vs Autogenic Drainage in People With Bronchiectasis | March 9, 2017 | June 30, 2020 |
| NCT02555865 | Unknown status | Aetiology of Children With Bronchiectasis in China | June 2016 | March 2022 | |
| NCT03320382 | Unknown status | Multiple Breath Washout, a Clinimetric Dataset | May 5, 2017 | March 2024 | |
| NCT03966066 | Unknown status | N/A | Long-term Prognosis of Children With Bronchiectasis Treated With Low-dose Erythromycin Intervention | August 2019 | July 2020 |
| NCT03818646 | Unknown status | Functional Respiratory Imaging in Bronchiectasis | January 2019 | April 2019 | |
| NCT04017312 | Unknown status | N/A | A Pilot Study to Evaluate the Use of the Vest® System for Treatment of Bronchiectasis Patients in the Home Setting | August 23, 2019 | November 2020 |
| NCT01354912 | Unknown status | The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis | May 2011 | July 2013 | |
| NCT01410422 | Unknown status | Metabolomic Analysis of Exhaled Breath Condensates in Patients With COPD and Bronchiectasis | May 2011 | April 2014 | |
| NCT04090294 | Unknown status | Early Phase 1 | Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis | October 1, 2019 | November 2020 |
| NCT04101448 | Unknown status | Prevalence of Bronchiectasis in COPD Patients | September 30, 2019 | September 30, 2020 | |
| NCT05189613 | Unknown status | N/A | Mepolizumab Effectiveness in Severe Eosinophilic Asthma and Bronchiectasis | September 1, 2021 | December 31, 2022 |
| NCT01677403 | Unknown status | Phase 4 | A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis | August 2012 | December 2014 |
| NCT00129350 | Unknown status | Phase 1 | Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation | September 2004 | February 2008 |
| NCT01688180 | Unknown status | The Prevalence and Impact of Depression and Anxiety Symptoms in Patients With Non-CF Bronchiectasis | December 2012 | May 2014 | |
| NCT01761214 | Unknown status | N/A | Bacteriology and Inflammation in Bronchiectasis | September 2012 | December 2023 |
| NCT02913365 | Unknown status | Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis | October 2012 | June 2017 | |
| NCT04215172 | Unknown status | Macrolides in COPD- Bronchiectasis Overlap | August 1, 2020 | July 1, 2022 | |
| NCT01801657 | Unknown status | The Role of Viral Infection in Acute Exacerbations of Non-cystic Fibrosis Bronchiectasis in Adults | February 2013 | April 2014 | |
| NCT04225650 | Unknown status | Prevalence of Respiratory Impairment During IBD | May 1, 2020 | August 2020 | |
| NCT05293314 | Unknown status | Assessment of an Exhaled Breath Test to Detect Bronchiectasis | July 1, 2022 | December 30, 2023 | |
| NCT04310618 | Unknown status | Mucus Solids Concentration in Patients With Bronchiectasis | December 21, 2020 | August 2023 | |
| NCT03903913 | Unknown status | Phase 2 | Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis | August 8, 2019 | August 2022 |
| NCT01268475 | Unknown status | Exercise Capacity in Bronchiectasis Resection | March 2009 | ||
| NCT02574143 | Unknown status | The PROspective German NOn-CF bronchiectaSIS Patient Registry | July 2015 | July 2021 | |
| NCT02564731 | Unknown status | Prognosis of Bronchiectasis in Children--A Multicenter Prospective Cohort Study | June 2016 | March 2022 | |
| NCT03902236 | Unknown status | Reaction Time and Postural Control in Individuals With Cystic Fibrosis and Bronchiectasis | March 1, 2019 | November 4, 2019 | |
| NCT03737617 | Withdrawn | Phase 4 | Immunoglobulin Replacement Therapy for Immunoglobulin G Subclass 2 Deficient Patients With Bronchiectasis | August 5, 2022 | December 1, 2024 |
| NCT03376204 | Withdrawn | Pain Mechanisms in Patients With Bronchiectasis | September 29, 2017 | November 30, 2019 | |
| NCT01315626 | Withdrawn | Bronchiectasis: Evaluation of an Educational Intervention | January 2011 | February 2011 |
- Disase is a (Disease Ontology)
- DOID:1176
- Cross Reference ID (Disease Ontology)
- ICD10CM:J47
- Cross Reference ID (Disease Ontology)
- ICD9CM:494
- Cross Reference ID (Disease Ontology)
- MESH:D001987
- Cross Reference ID (Disease Ontology)
- MIM:211400
- Cross Reference ID (Disease Ontology)
- MIM:613021
- Cross Reference ID (Disease Ontology)
- MIM:613071
- Cross Reference ID (Disease Ontology)
- MIM:PS211400
- Cross Reference ID (Disease Ontology)
- NCI:C84475
- Cross Reference ID (Disease Ontology)
- ORDO:60033
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:155580000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0006267
- Exact Synonym (Disease Ontology)
- Polynesian bronchiectasis
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002110
- OMIM Phenotype Series Number (OMIM)
- PS211400
- ICD10 preferred id (Insert disease from ICD10)
- D0008046
- ICD10 class code (Insert disease from ICD10)
- J47
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001987