bipolar disorder

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Information
Disease name
bipolar disorder
Disease ID
DOID:3312
Description
"A mood disorder that involves alternating periods of mania and depression." [url:http\://en.wikipedia.org/wiki/Mood_disorder]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
WFS1 4 6,269,850 6,303,265 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05065489 Active, not recruiting Resting State Electroencephalogram for Psychotic Disorders September 1, 2021 December 1, 2023
NCT03481049 Active, not recruiting N/A Individualizing Incentives for Alcohol in the Severely Mentally Ill May 5, 2018 August 31, 2024
NCT05328297 Active, not recruiting Phase 2 A Study of JNJ-55308942 in the Treatment of Bipolar Depression June 3, 2022 May 21, 2024
NCT03641300 Active, not recruiting N/A Efficacy of Convulsive Therapies for Bipolar Depression September 21, 2018 August 30, 2024
NCT01383915 Active, not recruiting Clinical Risk State for Bipolar Disorder in Adolescents September 2009 December 31, 2023
NCT02888262 Active, not recruiting The Bipolar Illness Onset Study (the BIO Study) January 2016 December 2026
NCT05157386 Active, not recruiting Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety December 20, 2021 June 2024
NCT00512070 Active, not recruiting N/A Melatonin Metabolism Abnormality in Patients With Schizophrenia or Schizoaffective Disorder Treated With Olanzapine July 2007 December 2025
NCT05393648 Active, not recruiting N/A Bipolar Efficacy Biomarkers for rTMS July 5, 2022 December 31, 2025
NCT04945057 Active, not recruiting N/A AKTIBIPO-VALIDATION: A Study to Validate Benefits of Mindpax System in Managing Bipolar Disorder May 5, 2021 December 31, 2023
NCT03484494 Active, not recruiting N/A Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression May 29, 2018 August 30, 2023
NCT06370793 Active, not recruiting Ningbo Severe Mental Disorders Cohort July 1, 2018 December 31, 2026
NCT03615794 Active, not recruiting A Study of Pregnant and Postpartum Women With and Without Mood Disorders October 1, 2017 October 2024
NCT03622749 Active, not recruiting N/A Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders March 1, 2019 March 1, 2024
NCT03451630 Active, not recruiting N/A PCORI Integrated Care (IC) Models for Patient-Centered Outcomes April 23, 2018 August 31, 2024
NCT05249309 Active, not recruiting Naturalistic Study of Ketamine in the Treatment of Depression May 1, 2021 December 15, 2023
NCT04447807 Active, not recruiting N/A Metacognitive Training With Bipolar Disorder Patients. February 20, 2022 December 2024
NCT00421954 Completed Phase 3 Open-label Ziprasidone Study for Psychosis Treatment in Adolescents May 2006 May 2009
NCT01370668 Completed N/A Functional Remediation for Bipolar Disorder January 2009 December 2010
NCT00254488 Completed Phase 4 Treatment of Bipolar Mania in Older Adults November 2005 August 2011
NCT00288366 Completed N/A Anticonvulsant Mood Stabilizers, Antipsychotic Drugs and the Insulin Resistance Syndrome January 2006 December 2008
NCT05206734 Completed Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health January 5, 2022 August 15, 2023
NCT00095511 Completed Phase 3 Aripiprazole in Patients With Acute Mania June 2004 May 2007
NCT02306551 Completed Well Being And Resilience: Mechanisms of Transmission of Health and Risk September 2014 September 2021
NCT01670123 Completed N/A Development of a Personalized Real-time Intervention for Bipolar Disorder July 2010 June 2013
NCT01719315 Completed Neurophysiologic Correlates of Hypersomnia November 2012 June 2018
NCT00159796 Completed Phase 3 3-week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07009) December 14, 2004 April 28, 2006
NCT02670551 Completed Phase 3 Study on the Efficacy, Safety, and Tolerability of Cariprazine Relative to Placebo in Participants With Bipolar I Depression March 17, 2016 July 19, 2017
NCT00183352 Completed Reproductive Function and Mood in Women With Bipolar Disorder January 2004 July 2008
NCT01041976 Completed Phase 2 Supported Employment: Motivational Enhancement for Entry and Outcome January 2011 September 2015
NCT00134459 Completed Phase 3 Study Evaluating Bifeprunox in Bipolar Depression June 2005 May 2006
NCT02610725 Completed N/A Online Yoga for Individuals With Mood Disorders November 2015 February 20, 2018
NCT00183495 Completed Understanding Treatment Adherence Among Individuals With Bipolar Disorder March 2004 August 2007
NCT00116259 Completed N/A Aripiprazole in Children and Adolescents With Bipolar Disorder and Attention Deficit Hyperactivity Disorder (ADHD) March 2005 February 2008
NCT02397837 Completed Phase 4 Targeting Cognition in Bipolar Disorder With Pramipexole October 2014 July 26, 2018
NCT00223275 Completed Phase 4 Naltrexone for Bipolar Disorder and Alcohol Dependence May 2005 September 2007
NCT00595387 Completed N/A Effectiveness of Cognitive Behavioral Therapy for Treating Depression in People With Bipolar I Disorder September 2006 January 2013
NCT00927420 Completed Epidemiological Study to Evaluate Adherence to Treatment in Bipolar Disorder: Adherence Study July 2009 October 2009
NCT04325100 Completed N/A Intervention Targeting Motivational Negative Symptoms April 20, 2019 February 27, 2020
NCT00747201 Completed N/A Adapting the Bipolar Care Model for Chronic Care Management in Community-based Health Care Sites September 2009 March 2014
NCT00186485 Completed N/A Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Bipolar Depression May 2003 July 2010
NCT00110461 Completed Phase 3 Aripiprazole in Children and Adolescents With Bipolar I Disorder March 2005 February 2007
NCT01029145 Completed Management of Index Episode in Patients With Bipolar Disorder Treated by Seroquel XR December 2009 May 2010
NCT01106313 Completed Insulin Resistance in Patients With Major Depression July 2009 January 2016
NCT00545675 Completed Phase 4 Abilify in Bipolar Disorder for 24 Weeks Treatment Effectiveness December 2007 July 2010
NCT00083954 Completed Phase 3 Controlled Study of the Use of Quetiapine Fumarate in the Treatment of Patients With Bipolar Depression June 2004 August 2005
NCT01269710 Completed Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study October 2009 March 2011
NCT00194077 Completed Phase 3 Study of Aripiprazole (Abilify) in Children With Symptoms of Mania August 2004 January 2011
NCT00299715 Completed Phase 3 A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder February 2006 June 2007
NCT01248052 Completed Phase 1 A First Human Dose Study to Investigate Safety and Tolerability of LY2979165 in Healthy Volunteers November 2010 May 2011
NCT00090311 Completed Phase 3 Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children & Adolescents With Bipolar I Mania July 2004 July 2006
NCT01629355 Completed Auditory Brainstem Response as a Diagnostic Tool in Schizophrenia and Bipolar Disorder July 2012 August 2015
NCT00194012 Completed Phase 3 Study of Aripiprazole (Abilify) Versus Placebo in Children With Subsyndromal Bipolar Disorder August 2004 June 2012
NCT00036348 Completed Phase 3 Study of Aripiprazole in Patients With a History of Bipolar Disorder March 2000 June 2003
NCT02082678 Completed Phase 4 Ondansetron for Bipolar Disorder and Alcohol Use Disorders February 2014 May 2018
NCT00296283 Completed Phase 1 Family Workshops for Bipolar Disorder August 2005
NCT00145470 Completed Phase 3 12 Week Study of the Safety/Efficacy of Asenapine When Added to Lithium/Valproate in the Treatment of Bipolar Disorder (A7501008 / P05844 / MK-8274-017) June 2, 2005 March 22, 2007
NCT06296784 Completed N/A An E-health Psychoeducation for People With Bipolar Disorders May 26, 2021 November 15, 2021
NCT01371383 Completed N/A The Effect of Omega-3 Polyunsaturated Fatty Acids in the Treatment and Prevention of Relapse of Bipolar Disorder January 1, 2006 August 31, 2015
NCT00107926 Completed Phase 3 Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder October 2004 August 2007
NCT00586066 Completed Phase 4 Memantine and Cognitive Dysfunction in Bipolar Disorder November 2005 December 2009
NCT00563992 Completed Phase 1 Effectiveness of Lithium and Valproate in Treating High-Risk Bipolar Disorder January 2001 October 2008
NCT02481895 Completed N/A Efficacy of an Innovative E-neurocognitive Module for Bipolar Disorder January 2014 December 2018
NCT03497663 Completed N/A VIA Family - Family Based Early Intervention Versus Treatment as Usual September 25, 2017 January 1, 2021
NCT03203707 Completed N/A Early Assessment and Intervention for Adolescents at Risk for Bipolar Disorder April 1, 2011 February 28, 2015
NCT04671225 Completed N/A Psychoeducation for Patients With Bipolar Disorder in Rwanda January 15, 2021 December 31, 2022
NCT04612777 Completed N/A A Trial of "Opening Doors to Recovery" for Persons With Serious Mental Illnesses June 15, 2014 May 31, 2020
NCT00105794 Completed N/A Psychiatric Advance Directives for Improved Mental Health Care March 2004 June 2007
NCT02476877 Completed A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse June 2014 February 2016
NCT01431573 Completed N/A Wake Therapy in the Treatment of Depression July 2011 August 2016
NCT06113887 Completed N/A The Effect of Acceptance and Commitment of Bipolar Disorder Patients December 1, 2022 December 15, 2023
NCT01483391 Completed N/A Early Intervention for Youth at Risk for Bipolar Disorder October 6, 2011 September 15, 2020
NCT04244786 Completed N/A Treating Self Injurious Behavior: A Novel Brain Stimulation Approach October 1, 2019 July 29, 2022
NCT01736631 Completed N/A Cognitive Behavioural Therapy for Social Phobia in People With Bipolar Disorder March 2013 September 9, 2022
NCT00585702 Completed Antimanic Drug Use in Pregnancy August 2006 March 2012
NCT06315049 Completed N/A Music Therapy to Reduce Anxiety in Community-Dwelling Individuals With Severe Mental Illness June 26, 2023 July 31, 2023
NCT00181727 Completed Phase 4 Study of Depakote ER for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder January 2004 November 2006
NCT01973478 Completed N/A Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression June 3, 2014 November 27, 2018
NCT00580268 Completed Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity August 2005 July 2013
NCT00741299 Completed A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder August 2007 September 2009
NCT02221336 Completed N/A Daily Subjective and Objective Smartphone Measures of Illness Activity to Treat Bipolar Disorder- The MONARCA II Trial September 2014 January 2018
NCT01869374 Completed Phase 1/Phase 2 Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults August 2012 August 2020
NCT00254774 Completed Phase 3 Efficacy and Safety of Quetiapine Compared With Valproate in the Treatment of Patients With Bipolar Disorder and Rapid Cycling January 2002 March 2006
NCT00431184 Completed Phase 2 Effects of Pentazocine Versus Lorazepam on Manic Symptoms January 2007 March 2011
NCT02308956 Completed Phase 3 Task Sharing for the Care of Severe Mental Disorders in a Low-income Country March 2015 November 16, 2017
NCT00986336 Completed Phase 1 A Pharmacokinetic Study of Risperidone and Topiramate Administered Alone and in Combination in Patients With Bipolar Disorder or Schizoaffective Disorders February 2001 November 2002
NCT00713804 Completed Phase 3 Impact of Genetic Counseling for Individuals With Mental Illness July 2008 November 2011
NCT00999765 Completed Pilot Study: Mindfulness-Based Cognitive Therapy as a Tool for Prophylactic Mood Stabilizing Therapy in Bipolar Disorder June 2008 December 2012
NCT00211263 Completed N/A Bipolar Disorder Research Study for Ages 12 and Older November 2003 February 2007
NCT02845440 Completed N/A Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness July 14, 2016 January 12, 2021
NCT00102518 Completed Phase 3 Aripiprazole Open-Label, Safety and Tolerability Study September 2004 February 2007
NCT01455038 Completed Heart Rate Variability of Patients With Bipolar Disorder in Subsyndromal Depressive Phase January 2010 April 2010
NCT02566057 Completed N/A Prospective Pharmacogenetic Testing and Clinical Outcomes in Patients With Early-Phase Psychosis July 10, 2014 December 31, 2017
NCT00980863 Completed N/A Effects of a Lifestyle Intervention on Body Mass Index in Patients With Bipolar Disorder March 2005 August 2006
NCT00150605 Completed Phase 3 Safety of SPD417 Combined With Other Psychotropic Medications in the Treatment of Bipolar I Disorder February 2005 October 2005
NCT00224276 Completed Prevalence of Diabetes Mellitus Among Patients Treated With Atypical and Conventional Antipsychotics
NCT00246246 Completed Phase 3 A Randomized, Open-label Trial of Long-acting Injectable Risperidone Versus Oral Antipsychotic Medication in Patients With Bipolar Disorder January 2004 April 2006
NCT05408637 Completed Phase 2 Transcranial Photobiomodulation for Executive Function in Bipolar Disorder August 9, 2022 May 14, 2024
NCT00643123 Completed Phase 4 Allopurinol Add-on Treatment for Refractory Mania September 2007 June 2010
NCT00216554 Completed Phase 4 The Safety and Efficacy of Risperidone as Adjunctive Therapy to Mood Stabilizers in the Long-term Treatment of Bipolar Mania September 2004 March 2006
NCT05523076 Completed Transdiagnostic Markers of Cognitive Symptoms in Disorders Affective. March 15, 2018 December 31, 2021
NCT03220776 Completed Phase 2 Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics August 7, 2017 November 21, 2022
NCT05340504 Completed Phase 2 Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder May 13, 2022 June 21, 2023
NCT00050700 Completed Brain Imaging in Depression December 16, 2002 May 14, 2010
NCT01720316 Completed Phase 2 Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders December 10, 2012 May 31, 2017
NCT03403790 Completed A Survey on Quetiapine Extended-release Tablets in Patients With Depression in Bipolar Disorder January 15, 2018 March 19, 2020
NCT00221403 Completed Phase 3 Placebo Controlled Trial of Valproate and Risperidone in Young Children With Bipolar Disorders September 2004 May 2011
NCT05936983 Completed Comparison of Physical Fitness, Physical Activity Level in Patients With Bipolar Disorder and Schizophrenia June 2, 2023 June 20, 2023
NCT00397020 Completed Phase 4 Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed Episodes December 2006 December 2008
NCT01833897 Completed Phase 4 NMDA Antagonists in Bipolar Depression March 2013 March 2016
NCT00094549 Completed Phase 4 Olanzapine vs. Comparator and Placebo in the Treatment of Patients With Bipolar I Disorder October 2004 December 2006
NCT00194038 Completed Phase 4 Aripiprazole in Late Life Bipolar Disorder April 2004 June 2006
NCT02150681 Completed Phase 1 Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders October 2012 October 2013
NCT00159783 Completed Phase 3 40 Week Extension Study Of Asenapine and Olanzapine For Bipolar Disorder (A7501007)(COMPLETED)(P05857) July 2005 April 2007
NCT04276883 Completed Phase 3 Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder February 24, 2020 May 21, 2020
NCT02210390 Completed N/A Culturally Adapted Psychological Intervention for Bipolar Disorder in Pakistan June 2012 May 2015
NCT00150553 Completed Phase 3 Efficacy and Safety of SPD417 in Treatment of Manic Symptoms in Adults With Bipolar I Disorder January 2005 October 2005
NCT01764074 Completed N/A Brief Sleep Intervention for Bipolar Disorder January 2013 November 15, 2018
NCT00044616 Completed Phase 4 Relapse Prevention for Bipolar Type-II Disorder February 2001 January 2007
NCT02006862 Completed eVAluatIon of OLanzapine TreatmEnT January 2014 December 2014
NCT00661869 Completed N/A Outcome Evaluation of Solutions for Wellness and Team Solutions Program in Patients With Severe Mental Illness September 2006 January 2008
NCT00226135 Completed Phase 3 Prophylactic Effect of Lamotrigine Compared With Lithium in Bipolar Disorder March 2001 December 2006
NCT00282464 Completed Phase 3 A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression. February 2006 March 2008
NCT01152034 Completed N/A MAPS Group Therapy Model for Bipolar Disorder July 2009 April 2011
NCT01015586 Completed Phase 4 Treatment of Alcohol Dependence and Comorbid Bipolar Disorder February 2010 September 2014
NCT00690248 Completed Depressive Symptoms in Acute Manic Episode November 2007 December 2008
NCT02560701 Completed High Deductible Health Plans and Bipolar Disorder September 2015 August 2018
NCT03872596 Completed Phase 1 Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar Disorder March 27, 2019 November 27, 2019
NCT01245348 Completed Relative Effectiveness of Schizophrenia Therapy Study December 2010 December 2012
NCT05480124 Completed N/A Bipolar Transcranial Alternating Current Stimulation (tACS) April 20, 2023 January 6, 2024
NCT03197168 Completed N/A Psychosocial Intervention to Reduce Self-stigma and Improve Quality of Life Among People With Mental Illness in Chile March 2014 March 2016
NCT00321516 Completed Phase 1 Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder July 2006 February 2007
NCT00572117 Completed Phase 4 Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder August 2007 July 2014
NCT02276469 Completed N/A Peer Support for Severe Mental Disorders July 2011 December 2014
NCT01303601 Completed Phase 4 Efficacy of Olanzapine Monotherapy for Treatment Bipolar Ⅰ Depression January 2009 October 2010
NCT00571688 Completed Phase 4 Does Risperidone Consta Reduce Relapse and Rehospitalization in Bipolar Disorder? November 2007 February 2009
NCT00924976 Completed N/A Improving Representative Payeeship for People With Psychiatric Disabilities and Their Families May 2008 April 2011
NCT00001146 Completed Phase 2 Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial October 1999 August 2002
NCT03638687 Completed Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers May 2014 August 2020
NCT00294255 Completed Phase 4 Risperidone Plus Mood Stabilizer in Treatment of Mixed Mania March 2003 October 2006
NCT03017781 Completed A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder October 25, 2016 April 30, 2021
NCT01552837 Completed N/A Effects of Quetiapine on Ultrastructural Hippocampal and Neurochemical Changes in Patients With Bipolar Disorder: Searching for Antidepressant and Mood Stabilising Neurophysiology December 2007 December 2010
NCT02418910 Completed Effectiveness of Two Self Assessment Tools: KIOS-Bipolar or eMoods October 2015 April 2017
NCT00763919 Completed N/A Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder July 2008 October 2010
NCT01750255 Completed N/A Effect of Pharmaceutical Care in Patients With Bipolar I Disorder (BD I) November 2011 June 2014
NCT02553161 Completed N/A Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth December 2015 December 2022
NCT00181844 Completed Phase 4 Lamotrigine for the Treatment of Mania in Youth Ages 6-17 With Bipolar Disorder January 2005 April 2008
NCT03360695 Completed N/A Bridge: Proactive Psychiatry Consultation and Case Management for Patients With Cancer December 11, 2017 December 1, 2022
NCT00240110 Completed Phase 1/Phase 2 Valproate Efficacy in Cocaine-Bipolar Comorbidity March 2006 March 2014
NCT04870710 Completed N/A Feasibility Electrical Stimulation Study for Visual Hallucinations October 1, 2020 January 2, 2022
NCT03203720 Completed N/A Brief Motivational Intervention to Improve Medication Adherence for Adolescents With Bipolar Disorder July 11, 2011 December 30, 2014
NCT00650611 Completed Phase 2 A Study of the Safety and Tolerability of Oral Ziprasidone in Children and Teens With Psychotic Disorders December 2003 March 2005
NCT00482482 Completed N/A Yoga in Unipolar and Bipolar Disorders September 2007 March 2011
NCT00167310 Completed Phase 2 Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation September 2005 December 2015
NCT04304417 Completed The Role of Group Identity on the Community Integration of People With Severe Mental Disorder February 17, 2020 April 1, 2022
NCT00619723 Completed Phase 4 Citicoline for Bipolar 1 Disorder and Cocaine Dependence April 2008 April 2012
NCT01259427 Completed Phase 2 Reducing Internalized Stigma in People With Serious Mental Illness October 2011 September 2015
NCT03572426 Completed Ion Channel Genetic Biomarkers: Diagnostic Capabilities in the Assessment of Bipolar Disorder June 13, 2018 April 4, 2019
NCT00593099 Completed Phase 1/Phase 2 A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder April 2004 June 2006
NCT00214877 Completed Phase 3 Methylene Blue for Cognitive Dysfunction in Bipolar Disorder November 2003 October 2007
NCT01542008 Completed N/A Treatment Adherence Enhancement in Bipolar Disorder April 2012 August 2017
NCT00043693 Completed N/A Family Intervention for Mental Illness and Substance Abuse April 2002 December 2008
NCT02466685 Completed Phase 2 Testing the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar Patients September 2015 December 2022
NCT00154323 Completed Phase 4 The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Bipolar Disorder I or II This Study is Not Being Conducted in the United States. January 2003 January 2006
NCT04134871 Completed N/A Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI August 22, 2019 December 31, 2022
NCT02357290 Completed Phase 4 Open-Label Study of N-Acetylcysteine in Children and Adolescents 5-17 With Bipolar Spectrum Disorders January 2014 September 24, 2018
NCT04098497 Completed Phase 1 Modeling Mood Course to Detect Markers for Effective Adaptive Interventions- Aim 3 September 13, 2019 October 21, 2020
NCT01349907 Completed Phase 3 Extension Study of Asenapine [P06107 (NCT01244815)] for Pediatric Bipolar Disorder (P05898) June 16, 2011 September 5, 2014
NCT00472615 Completed Menstrual Effects On Mood Symptoms in Bipolar Disorder August 2006 June 2008
NCT00143182 Completed Phase 3 9 Week Extension Study of Asenapine and Olanzapine in Treatment of Mania (P07007)(COMPLETED) January 7, 2005 June 28, 2006
NCT01996293 Completed Pregnant Women Taking Lamictal for Bipolar Disorder September 2013 December 2020
NCT01919892 Completed Phase 4 Longitudinal Study on the Neuroprotective and Neurotrophic Effects of Lithium September 2010 November 2012
NCT00833976 Completed Phase 4 Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia July 2009 March 2013
NCT00601536 Completed N/A Bioequivalency Study of 300 mg Lithium Carbonate Under Fasting Conditions April 2003 May 2003
NCT01737268 Completed Phase 3 Long-term Study of FK949E in Elderly Bipolar Disorder Patients October 29, 2012 June 29, 2016
NCT00181779 Completed Phase 4 Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder February 2003 December 2006
NCT00221975 Completed Phase 3 Combination Therapy in Dual Diagnosis Bipolar Rapid Cycling July 2002 December 2007
NCT01053429 Completed A Non-Interventional Post-Marketing Surveillance Study to Evaluate the Safety and Efficacy of Zeldox Capsule June 2005 February 2010
NCT01811147 Completed Phase 4 Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI November 2011 June 2018
NCT02918370 Completed Phase 3 Aripiprazole for Bipolar Disorder and Alcohol Use Disorder November 2016 June 30, 2023
NCT00222755 Completed N/A Improving Care for Patients With Bipolar Disorder January 2006 March 2007
NCT00601575 Completed N/A Bioequivalency Study of 450 mg Lithium Carbonate Under Fed Conditions October 2002 November 2002
NCT00961935 Completed Pediatric Bipolar Disorder Study at UCLA August 2008 September 2011
NCT02150577 Completed N/A Implementation Trial of Evidence Based Practices for Mood Disorders May 1, 2014 November 1, 2017
NCT01196676 Completed Phase 1 Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4451 August 2010 April 2011
NCT00829400 Completed N/A Cognitive Training to Enhance VA Work Program Outcomes May 2008 December 2016
NCT01793324 Completed EMR Data to Assess Monitoring of Patients Treated With Quetiapine April 2012 June 2013
NCT03235908 Completed Copeptin in Outcome Prediction of an Acute Psychotic Episode May 1, 2017 July 31, 2020
NCT02800161 Completed Phase 3 Trehalose as add-on Therapy in Bipolar Depression June 2016 October 2022
NCT00609193 Completed Functional and Neurochemical Brain Changes in First-episode Bipolar Mania January 2008 July 2015
NCT03575728 Completed N/A Telemetry-Triggered Educational Content Delivery Using MyChart in Mood Disorders May 15, 2019 December 15, 2019
NCT01797575 Completed Phase 2 N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder January 2013 February 1, 2017
NCT00602394 Completed N/A Bioequivalency Study of 300 mg Lithium Carbonate Under Fed Conditions May 2003 May 2003
NCT02675712 Completed Effect of African Drumming in Mood Disorders April 2015 August 2015
NCT02402010 Completed N/A Pilot Study of Adjunctive Yoga for Bipolar Depression January 2014 January 2016
NCT04923204 Completed Utility of the Pharmacogenetic Information Provided by NEUROPHARMAGEN in the Treatment of Bipolar Depressionwith Bipolar Depression March 1, 2016 December 5, 2019
NCT00723450 Completed Phase 3 Lamictal as Add-on Treatment for Bipolar I Disorder in Pediatric Patients July 2008 August 2013
NCT00257972 Completed Phase 3 Study of Aripiprazole in Patients With Bipolar I Disorder October 2004 December 2007
NCT03367533 Completed Phase 1 Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response November 29, 2018 July 8, 2022
NCT05809193 Completed N/A Investigation of the Effects of Family-Focused Therapy in the Early Period of Bipolar Disorder and Psychotic Disorder April 1, 2022 December 31, 2023
NCT02453438 Completed Mood Patient Powered Research Network (MoodNetwork) March 2015 March 2019
NCT02423824 Completed Phase 3 Cognitive Dysfunction and Glucagon-like Peptide-1 Agonists May 2015 May 2016
NCT01195363 Completed Phase 4 Quetiapine Sr as Adjunctive Treatment In Mixed States of Bipolar Disorder April 2007 June 2011
NCT01058096 Completed Phase 3 Safety and Efficacy of Cariprazine for Mania February 2010 July 2011
NCT00280293 Completed Phase 4 Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency March 2006 January 2010
NCT00382915 Completed Measuring Smoking Behavior in People With Schizophrenia and Bipolar Disorder October 2006 December 2010
NCT05929183 Completed N/A Neuronavigation rTMS to Improve Depressive Episodes of Bipolar Disorder in Adolescent September 1, 2022 July 1, 2023
NCT00895258 Completed Phase 2 Cognitive Training to Improve Work Outcomes in Severe Mental Illness April 2008 March 2014
NCT00314314 Completed Phase 3 The Effect of Intranasal Insulin on Neurocognitive Function in Euthymic Patients With Bipolar Disorder May 2006 March 2009
NCT06041646 Completed Phase 4 Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder October 12, 2023 April 29, 2024
NCT02930005 Completed Phase 2 Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders August 7, 2015 October 6, 2016
NCT01485640 Completed Phase 3 Lurasidone Extended Use Study June 2011 February 2014
NCT00223210 Completed Phase 4 An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence November 2005 December 2007
NCT01795326 Completed Physician Survey on Monitoring of Patients Treated With Quetiapine June 2013 September 2013
NCT01882608 Completed N/A Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood Disorders October 2013 March 2016
NCT01992302 Completed Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients June 2004 November 2013
NCT00190892 Completed Phase 4 Olanzapine Plus Carbamazepine in the Treatment of Bipolar I Mania September 2004 June 2006
NCT01431326 Completed Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care November 2011 November 2019
NCT01567943 Completed N/A Contingency Management of Alcohol Abuse in the Severely Mentally ILL March 2012 February 2016
NCT02041962 Completed N/A Implementing Health Plan-Level Care Management for Solo & Small Practices July 2014 January 2018
NCT01926613 Completed N/A Thinking Skills for Work in Severe Mental Illness April 2006 October 2011
NCT00597896 Completed Phase 4 Cognitive Enhancement in Bipolar Disorder October 2005 April 2011
NCT01818622 Completed N/A Virtual Darkness as Additive Treatment in Mania February 2012 March 2015
NCT02893007 Completed N/A A Brief Family-centered Care Program for Bipolar Disorder March 2010 December 2012
NCT02498730 Completed N/A Interval Training in Bipolar Disorder August 2015 July 2017
NCT00472641 Completed Phase 4 Geodon in Weight Loss Study for Bipolar Disorders January 2007 December 2009
NCT01012180 Completed Parents With Bipolar Disorder: Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child October 23, 2009 June 7, 2013
NCT00393978 Completed Phase 4 Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania November 2006 March 2014
NCT02843282 Completed N/A Reasoning Training in Individuals With Bipolar Disorder April 2014 February 2018
NCT01133821 Completed Phase 4 Acute Psychotherapy for Bipolar II Depression August 2010 October 2015
NCT02750904 Completed N/A Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder April 3, 2017 May 14, 2019
NCT00183469 Completed Phase 4 Maintenance Treatment of Bipolar Depression December 2004 April 2009
NCT03049813 Completed N/A Virtual Reality Job Interview Training in Severe Mental Illness June 1, 2017 July 31, 2022
NCT01476527 Completed N/A Deep Brain Stimulation for the Treatment of Refractory Bipolar Disorder May 2011 June 2014
NCT01944293 Completed Phase 1/Phase 2 Ketamine for Suicidality in Bipolar Depression September 2013 October 2018
NCT02272010 Completed N/A Dietary Intervention for Bipolar Disorder October 2014 April 2019
NCT02421965 Completed N/A Comparing Mobile Health (mHealth) and Clinic-Based Self-Management Interventions for Serious Mental Illness June 2015 December 2017
NCT01470781 Completed N/A Treatment to Enhance Cognition in Bipolar Disorder June 2011 August 1, 2016
NCT00602381 Completed N/A Bioequivalency Study of 450 mg Lithium Carbonate Under Fasting Conditions November 2002 November 2002
NCT02404246 Completed N/A Pilot Trial of Peer Support for Bipolar Disorder December 2005 September 2009
NCT00870311 Completed Phase 4 Investigation of Lithium on Signal Transduction, Gene Expression and Brain Myo-Inositol Levels in Manic Patients March 1996 April 2004
NCT02256566 Completed N/A Cognitive Training for Mood and Anxiety Disorders September 2014 April 20, 2016
NCT01361698 Completed N/A Illness Management and Recovery (IMR) in Danish Community Mental Health Centres February 2011 December 2014
NCT01799291 Completed N/A Cognitive De-Biasing and the Assessment of Pediatric Bipolar Disorder September 2012 August 2013
NCT02558075 Completed N/A Mood Lifters: A Self Help Program February 1, 2018 December 1, 2022
NCT01892306 Completed N/A Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder June 2013 December 2014
NCT00253071 Completed N/A Early Integrated Intervention in Severe Affective Disorders December 2005 March 2012
NCT00621777 Completed Phase 4 A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder February 2008 May 2013
NCT00012558 Completed N/A Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) September 1998 September 2005
NCT06053346 Completed N/A Partners in Wellness: Evaluation of a Pay for Performance Program for High-Utilizers of Mental Health Services August 1, 2016 July 1, 2023
NCT01981018 Completed N/A MAPP: Imagery-focused Therapy for Bipolar Disorder November 2013 July 2015
NCT02490241 Completed Lithium Therapy: Understanding Mothers, Metabolism and Mood April 2015 June 2020
NCT03050853 Completed N/A The Appeal and Impact of E-cigarettes in Smokers With SMI March 1, 2017 January 31, 2021
NCT00181636 Completed N/A Galantamine-CR and Cognitive Dysfunction in Bipolar Disorder October 2006
NCT02334228 Completed N/A Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness September 2006 August 2009
NCT02507349 Completed N/A Person-Centered Versus Measurement-Based Care in Mental Health August 2014 March 31, 2017
NCT00141271 Completed Phase 3 A Six-Week Study Evaluating The Efficacy And Safety Of Geodon In Patients With A Diagnosis Of Bipolar I Depression July 2005 February 2008
NCT00538629 Completed Non Interventional Study In Bipolar Disorder And Schizophrenia With Zeldox October 16, 2007 April 30, 2008
NCT00035230 Completed Phase 3 A Study on the Safety and Efficacy of Topiramate in the Treatment of Patients With Bipolar I Disorder July 2001 November 2002
NCT00892125 Completed Phase 1 A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder September 2006 March 2007
NCT02596698 Completed Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders October 31, 2015 March 31, 2018
NCT00841269 Completed Phase 2 Oral Uridine for Treatment of Bipolar Depression in Adolescents May 2009 June 2013
NCT02519543 Completed Phase 3 Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder September 2015 September 2020
NCT00129220 Completed Phase 3 Trial of Olanzapine in Patients With Manic or Mixed Episode of Bipolar I Disorder July 2005 January 2009
NCT01495741 Completed Post-Authorization Safety Surveillance Study of Asenapine in Participants With Bipolar Disorder (P08307) July 1, 2013 December 18, 2017
NCT00194129 Completed Phase 3 Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse Disorder November 1997 September 2006
NCT02989727 Completed Phase 4 Melancholic Symptoms in Bipolar Depression and Responsiveness to Lamotrigine November 2003 December 2017
NCT01805440 Completed N/A Uridine Adolescent Bipolar Depression Randomized Controlled Trial August 2013 December 2015
NCT00000369 Completed Phase 3 Maintenance Therapies in Bipolar Disorders June 1997 December 2002
NCT00309686 Completed Phase 3 A Study to Evaluate the Efficacy and Safety of Adjustable Doses of Extended-release (ER) Paliperidone Compared With Placebo, in Combination With Lithium or Valproate, to Treat Manic and Mixed Episodes in Patients With Bipolar I Disorder April 2006 August 2007
NCT01094249 Completed Phase 1 A Drug Interaction Study of Valproic Acid and Paliperidone Extended-Release (ER) in Patients With Schizophrenia, Bipolar I Disorder, or Schizoaffective Disorder February 2009 April 2009
NCT02077829 Completed N/A Implementation of Illness Management and Recovery in Mental Health Services March 2014 June 2015
NCT01503489 Completed Risk Factors for AD-Associated Switch to Mania October 2005 July 2011
NCT02506322 Completed N/A Adjuvant Psychotherapy for Relapse Prevention in Early Adulthood (< 35 yr.) of Bipolar Disorder August 1, 2015 March 31, 2020
NCT00176202 Completed Phase 3 Risperidone and Divalproex Sodium With MRI Assessment in Pediatric Bipolar April 2003 January 2008
NCT00099229 Completed Phase 3 Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder November 2004 August 2006
NCT03935854 Completed N/A Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness February 13, 2019 August 11, 2022
NCT02794129 Completed N/A fMRI of Flight of Ideas in Bipolar Disorder August 2013 September 2018
NCT00961961 Completed Phase 4 Prevention of Relapse & Recurrence of Bipolar Depression July 1, 2009 September 1, 2016
NCT00034580 Completed Phase 4 Olanzapine Versus Active Comparator in the Treatment of Bipolar I Disorder August 2001 August 2002
NCT00533260 Completed A Non-interventional Naturalistic Project to Investigate the Effect of the Use of SMS Text Service on Treatment Adherence in Patients Treated With Seroquel® (Quetiapine) July 2007 April 2008
NCT02342366 Completed N/A Characterization of the Prosocial and Prosexual Effects of GHB February 2012 December 2014
NCT04655287 Completed A Register Study of Effects Following Local Variation in Rates of Involuntary Care January 1, 2015 December 31, 2018
NCT00242619 Completed N/A Insulin Resistance in Patients With Mood Disorder July 2007 December 2009
NCT01820286 Completed N/A Positive Psychology for Mood Disorders March 2013 June 10, 2016
NCT00178958 Completed N/A Evaluation of QTc Interval by Continuous Holter ECG Recording in Antipsychotic Drug-treated Patients With Schizophrenia August 2003 June 2006
NCT02855762 Completed N/A Targeting the Microbiome to Improve Clinical Outcomes in Bipolar Disorder September 8, 2016 January 31, 2019
NCT03913013 Completed Phase 1/Phase 2 Technology Enhanced Family Treatment November 15, 2018 October 20, 2021
NCT03404882 Completed N/A Peer Support Experience for Patients Discharged From Acute Psychiatric Care June 1, 2019 November 1, 2020
NCT00391261 Completed Phase 4 An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications. July 2006 October 2007
NCT01704352 Completed N/A Cognitive Behavioral Therapy for Insomnia in Euthymic Bipolar Disorder January 2013 August 2018
NCT00223496 Completed Phase 4 12- Week Open Label Treatment of Refractory Bipolar Depression September 2004 September 2009
NCT00224380 Completed N/A Medication Adherence in Older Adults With Serious Mental Illness July 2003 February 2005
NCT00667745 Completed Phase 4 Effectiveness of Lithium Plus Optimized Medication in Treating People With Bipolar Disorder April 2008 March 2010
NCT00202293 Completed Phase 4 Comparison of Combination Olanzapine+Lithium or Chlorpromazine+Lithium in Treatment of First Manic Episode With Psychotic Features October 1, 2001 November 1, 2015
NCT02212041 Completed N/A Electronic Cigarettes in Smokers With Mental Illness September 24, 2014 May 2, 2017
NCT00097032 Completed Phase 3 Study Measuring Differences in Cognition Due to Sedative Effects of Risperidone and Quetiapine in Stable Bipolar I Outpatients October 2004 May 2005
NCT01880957 Completed N/A PET and MRI Brain Imaging of Bipolar Disorder November 8, 2011 June 23, 2017
NCT01876524 Completed N/A tRNS in Anterior Cingulate Cortex Reduces Craving Over Dual Pathology Patients July 2013 September 2014
NCT01403662 Completed Phase 3 Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression July 2011 December 2014
NCT00181870 Completed Phase 4 Equetro for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder July 2005
NCT00596622 Completed Phase 4 FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder August 2007 November 2012
NCT02515773 Completed Phase 4 Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs December 2015 June 2023
NCT01965925 Completed Phase 4 Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder With Modafinil January 2014 November 9, 2017
NCT00459264 Completed N/A Prevention of Mood Disorders by Folic Acid Supplementation December 2005 December 2011
NCT00080314 Completed Phase 3 Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode January 2004 October 2006
NCT01620866 Completed N/A A Eye Movement Desensitization Reprocessing (EMDR) Study in Bipolar Traumatized Patients November 2010 June 2012
NCT04939818 Completed Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders June 14, 2021 September 15, 2022
NCT00332098 Completed Phase 3 Effectiveness of Family-Focused Treatment Plus Pharmacotherapy for Bipolar Disorder in Adolescents August 2006 July 2012
NCT04034147 Completed Clinical Determinants of the Discrepancy Between Objective and Subjective Cognition in the Versailles FACE-BD Cohort January 1, 2009 December 31, 2018
NCT00252226 Completed Phase 3 Quetiapine (Seroquel) Maintenance Treatment in Early Onset Bipolar Spectrum Disorders June 2004 December 2007
NCT06005155 Completed Lithium Versus Anticonvulsants and the Risk of Physical Disorders June 1, 2022 July 1, 2023
NCT02845453 Completed Phase 4 Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation January 20, 2017 April 7, 2021
NCT02520024 Completed N/A Assessing the Impact of Self-directed Care, Within a Medicaid-funded Environment,on Participation and Community Living January 2010 March 2012
NCT03208036 Completed N/A Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness July 15, 2018 February 28, 2022
NCT00107939 Completed Phase 3 Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder November 2004 April 2007
NCT00159562 Completed N/A Effects of Psycho-education of Patients With Bipolar Disorder September 2005 December 2012
NCT03338673 Completed N/A Brain Stimulation and Cognitive Training October 11, 2018 September 27, 2019
NCT02742064 Completed Quantified Mobile Sensing for Improving Diagnosis and Measuring Disease Progression February 2015 March 31, 2018
NCT00545142 Completed Phase 4 Abilify in Bipolar Disorder for 6 Weeks Treatment Effectiveness October 2007 June 2010
NCT00264173 Completed Phase 4 VALID : VAlproate Versus LIthium in Bipolar Disorders February 2004 September 2006
NCT02860910 Completed N/A Cognitive Behavioral Group Therapy for the Management of Menopause Symptoms in Mood Disorders July 2016 October 2018
NCT00830310 Completed N/A Customized Medication Adherence Enhancement for Adults With Bipolar Disorder January 2009 October 2010
NCT04348604 Completed N/A Improving Adherence in Adolescents and Young Adults With Bipolar Disorder March 15, 2021 September 1, 2023
NCT05357859 Completed N/A Vitamin D for Cognition in Bipolar Disorder May 3, 2022 November 20, 2023
NCT00488566 Completed Phase 1 GSK Drug Single Dose Escalation And Their Effect On Resting Motor Threshold In Healthy Volunteers May 31, 2007 May 31, 2008
NCT02120937 Completed N/A Mindfulness in Mood Dysregulated Youth March 2014 March 2016
NCT00035802 Completed Phase 3 A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder January 2002 April 2002
NCT04269772 Completed N/A Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT January 21, 2020 November 2, 2022
NCT01864551 Completed Phase 4 Olanzapine Compared to Lamotrigine in the Prevention of Depressive Episode in the Patients With Bipolar Disorder August 2008 September 2012
NCT06081634 Completed N/A Study Efficacy of Enhancing Cognitive Reserve in Patients With a First Bipolar Episode January 1, 2019 June 30, 2023
NCT05179785 Completed N/A Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder March 23, 2022 July 31, 2023
NCT00139594 Completed Phase 4 Open Label Extension Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar I Disorder December 2004 July 2007
NCT02918097 Completed Phase 4 Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode May 2010 September 2015
NCT01804257 Completed N/A Event Marker Ingested To Trigger Event Recorder 3.0 Psychiatry Study May 2010 May 2011
NCT00206141 Completed Phase 3 Seroquel in Bipolar Depression Versus Lithium August 2005 May 2007
NCT00485680 Completed Phase 3 Olanzapine Versus Comparator in the Treatment of Bipolar Disorder December 2003 June 2005
NCT04797351 Completed N/A Bi-REAL - DBT Skills Online Group Intervention for Bipolar Disorder September 1, 2020 January 31, 2022
NCT00913848 Completed Phase 1 To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fed Conditions October 2005 October 2005
NCT01166425 Completed Phase 2/Phase 3 Safety and Efficacy Study of Lithium for the Treatment of Pediatric Mania. June 2010 April 2013
NCT00181922 Completed Phase 4 Ziprasidone for the Treatment of Mania in Children and Adolescents With Bipolar Disorder March 2002 December 2004
NCT03656770 Completed N/A Measuring Beliefs and Norms About Persons With Mental Illness December 13, 2016 June 8, 2018
NCT01498770 Completed An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308) April 1, 2013 December 21, 2017
NCT04068467 Completed N/A Evaluation of mHealth for Serious Mental Illness January 6, 2020 May 1, 2021
NCT00167479 Completed Phase 4 A Study of Risperidone Monotherapy in Bipolar Anxiety September 2003 September 2006
NCT00274677 Completed Phase 3 Depression And Bipolar Disorder November 2003 August 2005
NCT02334280 Completed N/A Evaluation of A Statewide Program to Prevent Early Mortality and to Promote Fitness in Persons With SMI September 2009 May 2013
NCT00250367 Completed Phase 3 A Study of the Effectiveness and Safety of Risperidone Versus Placebo as add-on Therapy to Mood Stabilizers, in the Treatment of Manic Episodes Associated With Bipolar Disorder. October 1997 November 1999
NCT06369805 Completed EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSION June 2, 2021 November 17, 2022
NCT00762268 Completed N/A A Trial of SAMe for Treatment-Resistant Bipolar Depression September 2008 September 2011
NCT04283188 Completed N/A 12-Month Extension Study of Dialectical Behavior Therapy for Youth With Bipolar Disorder February 19, 2020 January 13, 2023
NCT01731171 Completed N/A Probiotics to Prevent Relapse After Hospitalization for Mania November 2012 December 2016
NCT01395160 Completed Female Experiences and Brain Activity July 2011 November 2012
NCT00763581 Completed Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients April 2008 January 2009
NCT02456454 Completed Phase 3 Controlled Trial of Valproate Versus Risperidone in Young Children With Bipolar Disorder January 2006 June 2010
NCT00691353 Completed Subjective Well Being of Patients Receiving Atypical Antipsychotics as Monotherapy or Cotherapy With Mood Stabilizers April 2008 July 2008
NCT00181883 Completed Phase 4 Quetiapine for Mania In Preschool Children 4 to 6 Years of Age With Bipolar Disorder February 2005 April 2009
NCT00302133 Completed Phase 1/Phase 2 Optimizing Pharmacotherapy for Bipolar Alcoholics May 2006 July 2013
NCT04526067 Completed N/A In-person vs. Remote Wellness Support November 24, 2020 November 11, 2022
NCT00224822 Completed Phase 4 The Effects of Aripiprazole on Patients With Metabolic Syndrome March 2004 March 2007
NCT00252577 Completed Genetic Predictors of Lithium Response in Bipolar Disorder October 2005 May 2016
NCT02118623 Completed N/A Internet-Based Interventions for Bipolar Disorder (MoodSwings 2) January 2014 May 2016
NCT00400166 Completed N/A Recovery Guide Intervention for Recurrent Psychiatric Hospitalization December 2006 May 2009
NCT01932749 Completed N/A The Study of Effectiveness Repetitive Transcranial Magnetic Stimulation in Bipolar Depression August 2013 December 2013
NCT02527564 Completed Phase 4 Efficacy of Suvorexant to Treat Insomnia Related to Bipolar Disorder September 2015 March 1, 2021
NCT00391222 Completed Phase 3 A Study to Evaluate the Efficacy and Safety of Risperidone for the Prevention of Mood Episodes in the Treatment of Patients With Bipolar I Disorder November 2006 April 2009
NCT01428518 Completed Special Drug Use Investigation for LAMICTAL Bipolar November 2011 January 2016
NCT00303602 Completed Phase 4 Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height) March 2006 December 2007
NCT00789113 Completed Phase 1/Phase 2 Determination of Absorption and Elimination of Lamotrigine-XR November 2008 January 2011
NCT01329393 Completed Phase 1 Benefits Management for People With Psychiatric Disabilities August 2010 December 2013
NCT02090335 Completed N/A Health Promotion and Fitness for Younger and Older Adults With SMI May 2007 May 2013
NCT02924415 Completed N/A Future Internet Social and Technological Alignment Research April 2013 December 2015
NCT01884025 Completed N/A Get Moving and Get Well - Pilot Study June 2013 August 2015
NCT01342120 Completed PHARMO Institute Seroquel Safety Study September 2010 November 2010
NCT01542229 Completed N/A PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) May 3, 2012 December 31, 2016
NCT01282281 Completed Prospective Metabolic Monitoring of Youth and Adults With Bipolar Disorder January 2011 September 2013
NCT00226317 Completed N/A Aripiprazole in the Treatment of Bipolar Depression April 2004 February 2008
NCT00394095 Completed Phase 4 Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine December 2006 September 2009
NCT00305370 Completed Phase 4 Aripiprazole Associated With Methylphenidate in Children and Adolescents With Bipolar Disorder and ADHD August 2005 March 2008
NCT00252486 Completed N/A Omega-3 Fatty Acids in Children and Adolescents With Bipolar Disorder November 2001 June 2005
NCT03507647 Completed N/A Mindfulness Based Cognitive Therapy for Bipolar Disorder April 23, 2018 June 17, 2021
NCT03730064 Completed Early Phase 1 Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression November 1, 2018 March 1, 2021
NCT01331304 Completed Phase 4 Comparative Effectiveness Study for Bipolar Disorder September 2010 September 2013
NCT02756065 Completed Connectomics in Psychiatric Classification of Bipolar Disorder and Schizophrenia September 2014 August 2019
NCT00521365 Completed Phase 4 Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder. May 2008 August 2009
NCT02582905 Completed Phase 4 Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders May 2016 May 2023
NCT00097266 Completed Phase 3 Study of Aripiprazole in Patients With Acute Bipolar Mania December 2004 January 2007
NCT00177567 Completed Phase 4 Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study July 2001 January 2004
NCT02188121 Completed Phase 4 Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients February 2015 October 2021
NCT00952757 Completed Changes in Hyperprolactinemia Secondary to Antipsychotics After Switching to Quetiapine June 2007 August 2008
NCT03429361 Completed Testing the Value of Smartphone Assessments of People With Mood Disorders August 8, 2017 May 30, 2019
NCT00034229 Completed Phase 2 Clinical Trial of Felbamate for Treatment-Resistant Bipolar Depression April 2002 March 2006
NCT03207048 Completed N/A A Study of Repetitive Transcranial Magnetic Stimulation in Bipolar Patients July 10, 2017 December 30, 2019
NCT00217165 Completed Phase 2 Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study April 2005 December 2011
NCT00314821 Completed Phase 4 Ropinirole in the Treatment of Bipolar Depression September 2005 March 17, 2008
NCT02513654 Completed Phase 1 Pharmacokinetics, Safety and Tolerability of Repeat Dosing Lamotrigine in Healthy Chinese Subjects September 6, 2015 November 11, 2015
NCT01181960 Completed Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations August 2010 November 2013
NCT00194116 Completed Phase 3 Double-blind, Placebo-Controlled Divalproex Sodium ER in Bipolar I or Bipolar II Depression September 2004 February 2008
NCT03033420 Completed N/A Reducing the Rate and Duration of Re-ADMISsions Among Patients With Unipolar Disorder and Bipolar Disorder Using Smartphone-based Monitoring and Treatment - The RADMIS Trials May 15, 2017 May 1, 2021
NCT03166098 Completed The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders July 5, 2016 March 1, 2022
NCT01487668 Completed N/A Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders December 2011 May 2015
NCT04284813 Completed N/A Families With Substance Use and Psychosis: A Pilot Study September 24, 2020 July 7, 2022
NCT00399698 Completed Phase 3 Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone. May 1999 June 2005
NCT00001652 Completed The Evaluation and Follow-up of Patients With Bipolar Disorder December 1996 December 2002
NCT00809770 Completed N/A Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill April 2008 August 2013
NCT00057681 Completed Phase 3 Study of Outcome and Safety of Lithium, Divalproex and Risperidone for Mania in Children and Adolescents February 2003 December 2008
NCT00943085 Completed N/A Early Family-Focused Treatment for Youth at Risk for Bipolar Disorder April 2007 August 2011
NCT01615458 Completed N/A Disseminating Evidence-based Mood Disorder Chronic Care Models July 2010 May 2012
NCT00132678 Completed Phase 3 A Study of the Safety and Efficacy of Injectable Risperidone in the Prevention of Bipolar Mood Episodes February 2005 December 2007
NCT00576355 Completed N/A Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder December 2007 August 2010
NCT00986128 Completed Phase 1 A Pharmacokinetic Study of Lithium Before and During Topiramate Dosing in Bipolar Disorder Patients March 2001 October 2002
NCT03131505 Completed INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1 February 22, 2017 February 21, 2018
NCT00581009 Completed Phase 1/Phase 2 The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients May 30, 2001 December 9, 2011
NCT00037674 Completed Phase 3 A Study on the Safety and Efficacy of Topiramate in the Treatment of Patients With Bipolar I Disorder January 2001 May 2003
NCT04618250 Completed N/A Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA) November 6, 2020 September 30, 2021
NCT03013400 Completed Phase 2 Ebselen as an add-on Treatment in Hypo/Mania October 1, 2017 July 9, 2019
NCT00169052 Completed N/A Health Care Management and Rehabilitation Skills Training for Treating Serious Mental Illness in Older People September 2001 August 2006
NCT00145509 Completed Phase 3 40 Week Trial to Study the Safety of Asenapine When Added to Lithium or Valproate in the Treatment of Bipolar Disorder (A7501009)(P05786) August 2005 December 2007
NCT02978534 Completed Pharmacokinetics of Quetiapine Across Pregnancy and Postpartum March 2016 December 2020
NCT03062267 Completed N/A Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness October 1, 2017 May 31, 2020
NCT00490542 Completed Phase 2 Safety Study of Ziprasidone (Geodon) for the Depressive Mixed State December 2006 August 2009
NCT00006177 Completed Child & Adolescent Bipolar Disorder Brain Imaging and Treatment Study August 11, 2000
NCT00007761 Completed Phase 3 Does Bipolar Disease Program (BDP) Intervention Improve Long Term Manic and Depressive Symptoms. July 1997
NCT00477373 Completed Phase 4 Gulf Evaluation of VAlproate (Depakine Chrono) in maNia Study December 2006
NCT00485420 Completed N/A eCare for Moods: An Internet-based Management Program September 2002 December 2009
NCT00001170 Completed Study of the Psychological Development of Children of Parents With and Without Affective Disorders October 1979 February 2005
NCT00050206 Completed Phase 4 Olanzapine Versus Placebo in the Treatment of Mania in Adolescents With Bipolar I Disorder November 2002 May 2005
NCT00227838 Completed N/A Modifying Group Therapy for Bipolar Substance Abusers - 1 July 2003 August 2005
NCT01457235 Completed N/A The Effects of Cognitive Remediation on Cognitive Function in Remitted Bipolar Disorder - a Proof of Concept Study August 2011 January 2014
NCT01884844 Completed N/A Vitamin D Supplementation for Bipolar Depression June 2013 August 2015
NCT04481737 Completed N/A Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery February 1, 2021 January 1, 2024
NCT03315897 Completed Phase 2 Effects of Erythropoietin on Cognition and Neural Activity in Mood Disorders July 5, 2017 October 1, 2022
NCT01197846 Completed Phase 3 Efficacy of Quetiapine XR Versus Placebo as Concomitant Treatment to Mood Stabilizers in the Control of Subsyndromal Symptoms of Bipolar Disorder September 2010 July 2012
NCT00817154 Completed Phase 1 Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI) November 2009 December 2013
NCT02304432 Completed Early Phase 1 Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine September 27, 2015 July 31, 2017
NCT02670538 Completed Phase 3 Study of the Efficacy of a Fixed-dose Regimen of Cariprazine Compared to Placebo for Treatment of the Depressive Episode in Participants With Bipolar I Disorder March 31, 2016 January 18, 2018
NCT00411203 Completed Phase 3 Tamoxifen in Treatment of Acute Mania April 2003 June 2006
NCT03509181 Completed N/A Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification January 24, 2019 December 1, 2021
NCT00181831 Completed Spectroscopy in Children and Adolescents With Bipolar Disorder December 2002 November 2005
NCT00316303 Completed Phase 2 Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder February 2006 August 2012
NCT00312494 Completed Phase 3 3-week Study to Evaluate Efficacy and Safety of Ziprasidone With Either Lithium or Divalproex in Acutely Manic Subjects April 2006 December 2008
NCT03379597 Completed N/A A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder November 30, 2017 June 30, 2021
NCT00183703 Completed Understanding Treatment Adherence Among Individuals With Rapid Cycling Bipolar Disorder July 2004 August 2007
NCT00501865 Completed Phase 1 Study to Assess the Effect of Food on the Concentration of GW273225 in the Body of Healthy Male and Female Volunteers August 6, 2007 October 11, 2007
NCT01149551 Completed CSP #572 - Genetics of Functional Disability in Schizophrenia and Bipolar Illness February 2011 July 2014
NCT02287259 Completed Phase 4 Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study) November 2014 March 31, 2019
NCT03661333 Completed N/A Dissemination and Implementation Field Trial of Dialectical Behavior Therapy for Adolescents With Bipolar Disorder January 31, 2019 November 8, 2021
NCT00158990 Completed Phase 3 Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression. October 2002 July 2007
NCT00484471 Completed Phase 4 ABLE: Abilify in Bipolar Disorder for Long-term Effectiveness October 2007 November 2012
NCT02090595 Completed N/A Mindfulness Based Cognitive Therapy for Youth With Anxiety at Risk for Bipolar Disorder July 2013 July 2015
NCT00183443 Completed Phase 3 Treatment of Mania Symptoms With Drug Therapy February 2005 November 2010
NCT03528278 Completed Using Motivational Techniques to Increase Levels of Physical Activity in Long Term Psychiatric Inpatient Wards January 23, 2013 March 10, 2015
NCT00001285 Completed Effects of Sex Hormones on Circadian Rhythm in Men and Women August 1991 June 2000
NCT00790738 Completed Phase 3 Liothyronine (T3) for Bipolar Depression July 2008 July 2012
NCT00550407 Completed Phase 3 An Evaluation Of BW430C (Lamotrigine) Versus Placebo In The Prevention Of Mood Episodes In Bipolar I Disorder Patients November 2007 October 2009
NCT00205933 Completed Behavioral Processes Underlying Reward Processing in Depression April 2004 June 2007
NCT00813800 Completed N/A Varenicline in Bipolar Depressed Patients January 2009 February 2011
NCT00714818 Completed Phase 3 Impact of Genetic Counseling for Female First Degree Relatives of Individuals With Mental Illness August 2008 November 2011
NCT00309699 Completed Phase 3 A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder April 2006 November 2007
NCT00223509 Completed Phase 4 Lamictal As Add on Treatment in Mixed States of Bipolar Disorder August 2005 November 2007
NCT00071669 Completed Phase 2 Acupuncture as a Supplemental Treatment for Bipolar Depression November 2001
NCT00584961 Completed BIMET Study: Evolution of Metabolic and Cardiovascular Risks Factors in Patients With Bipolar Disorder May 2007 February 2009
NCT01764035 Completed N/A Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder February 2013 February 2016
NCT02644577 Completed Phase 4 Metformin for Treatment Antipsychotic-induced Metabolic Syndrome in Bipolar Disorder Patients June 2012 September 2015
NCT01866098 Completed N/A Naltrexone for Antipsychotic-Induced Weight Gain May 2013 April 7, 2019
NCT05683431 Completed N/A Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS) March 22, 2019 December 16, 2021
NCT00167323 Completed N/A Early Recovery Adherence Therapy for Bipolar Alcoholics July 2003 July 2007
NCT00113594 Completed Phase 3 Olanzapine Treated Adolescents With Schizophrenia or Bipolar I Disorder June 2005 March 2006
NCT01683539 Completed N/A Understanding How Cognitive Remediation Works September 2012 March 11, 2019
NCT01507753 Completed Phase 1 Omega-3 and Therapy Study for Childhood Bipolar Disorder- Not Otherwise Specified September 2011 September 2014
NCT00741598 Completed Phase 4 Efficacy and Safety of Galantamine for Improving Dysfunction in People With Bipolar Disorder September 2008 May 2014
NCT01721824 Completed N/A The Effect of IPS-MA- A Modified Early Supported Employment Intervention for Individuals With Mood or Anxiety Disorders October 2011 July 2016
NCT00913874 Completed Phase 1 To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fasting Conditions October 2005 October 2005
NCT01602510 Completed Phase 3 Lamotrigine Phase III Study in Bipolar I Disorder August 2012 December 2015
NCT03949218 Completed Bipolar Disorder and Oxidative Stress Injury Mechanism - Clinical Big Data Analysis Based on Machine Learning November 20, 2018 November 20, 2018
NCT00531518 Completed N/A Early Detection and Intervention for the Prevention of Psychosis October 2007 September 2013
NCT00699218 Completed N/A A Pilot Study on Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Bipolar Depression May 2008 April 2010
NCT01172652 Completed Phase 4 Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD) April 2010 October 2011
NCT05070052 Completed N/A MBCT and CBT for Youth at High Risk for Mood and Psychotic Disorders: a Randomized Controlled Trial January 14, 2020 March 9, 2022
NCT00365482 Completed Bipolar Disorder in Epilepsy August 2006 December 2011
NCT00522613 Completed N/A Recovery Group Pilot July 2005 December 2006
NCT03198364 Completed N/A Development of a Mobile Heath Augmented Brief Suicide Prevention Intervention for People With SMI March 1, 2018 June 30, 2021
NCT01447082 Completed General Practice Research Database Seroquel XR Safety Study October 2008 December 2012
NCT03358238 Completed N/A Modeling Mood Course to Detect Markers of Effective Adaptive Interventions November 27, 2017 June 19, 2019
NCT00029458 Completed Phase 2 Clozapine for Treatment-Resistant Mania January 2002 October 2005
NCT04011280 Completed Phase 4 Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness August 12, 2019 March 4, 2022
NCT00893581 Completed N/A Multimodal Neuroimaging of Treatment Effects in Adolescent Mania March 2009 March 2016
NCT00036582 Completed Phase 3 Clozapine vs. Placebo in Treatment-Refractory Bipolar Disorder in Children and Adolescents May 2002 February 2004
NCT00181987 Completed Phase 4 Concerta in the Treatment of ADHD in Youth and Adults With Bipolar Disorder August 2002 August 2005
NCT00137267 Completed N/A A Brief Community Linkage Intervention for Dually Diagnosed Individuals June 2005 June 2009
NCT04590300 Completed N/A Impact of Cognitive & Metacognitive Performance on Knowledge Learning When Conducting Therapeutic Education Programs October 6, 2020 December 31, 2022
NCT01770704 Completed Observation Study of the Clinical Management of Bipolar Disorder February 2013 July 2014
NCT02253225 Completed Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study January 2013 January 2020
NCT05815459 Completed Mobile Observation Of Depression July 15, 2022 February 1, 2023
NCT00184418 Completed The Immune System and Psychiatric Disorders January 2005 January 2008
NCT01010204 Completed Phase 4 Varenicline Treatment for Smoking Cessation in Patients With Bipolar Disorder January 2010 March 2013
NCT02473250 Completed Phase 4 Prediction of Clinical Response to SSRI Treatment in Bipolar Disorder Using Serotonin 1A Receptor PET Imaging January 2015 December 2019
NCT00428298 Completed Phase 2 Research Study of Bipolar Mood Symptoms and Cognitive Problems March 2007 October 2012
NCT01725308 Completed Phase 2/Phase 3 A Study to Evaluate the Efficacy of FK949E in Bipolar Disorder Patients With Major Depressive Episodes February 7, 2012 July 11, 2016
NCT00181935 Completed Phase 4 Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder March 2001 July 2004
NCT05693389 Completed N/A Efficacy of Acceptance and Commitment Therapy on Impulsivity and Suicidality Among Clients With Bipolar Disorders September 15, 2022 December 20, 2022
NCT00202306 Completed Phase 4 Indicated Prevention of Psychotic Disorders With Low-dose Lithium November 2001 December 2006
NCT02760693 Completed Bipolar Cohort Neunkirchen, Final Statement May 2000 March 2016
NCT00330005 Completed N/A A Pilot Study of Psychodynamic Psychotherapy for Bipolar Disorder July 2002 January 2005
NCT01342380 Completed Pioglitazone and Quetiapine XR Pharmacogenetic Study February 2011 May 2015
NCT02451670 Completed N/A Reducing Cardiovascular Risk in Adults With Serious Mental Illness January 20, 2016 September 19, 2018
NCT00330486 Completed Phase 1/Phase 2 Open Label Trial of Acamprosate in Bipolar Alcoholics April 2006 June 2007
NCT00520507 Completed Phase 4 An Investigation of the Sleep Architecture and Consequent Cognitive Changes in Olanzapine-Treated Depressed Patients October 2007 May 2009
NCT00276965 Completed Phase 3 Bipolar II Depression: Lithium, SSRI, or the Combination September 2006 July 2012
NCT00001772 Completed Evaluation of Patients With Rapid Cycling Bipolar Disorder (RCBD) September 1998 July 2001
NCT00044187 Completed Phase 4 The Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I Disorder April 2001 September 2003
NCT00550394 Completed Phase 4 Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults April 2008 June 2010
NCT00457197 Completed Phase 4 Quetiapine for Bipolar Disorder and Alcohol Dependence March 2007 July 2011
NCT00036101 Completed Phase 3 Study of Aripiprazole in the Treatment of Patients With Acute Symptoms in Bipolar Disorder February 2002 January 2003
NCT00538122 Completed Changes in Heart Rhythms Associated With Antipsychotic Drug Treatment July 2007 September 2008
NCT00191997 Completed Phase 4 Optimal Length of Treatment Continuation With Olanzapine After Remission of Manic or Mixed Episode October 2004 March 2006
NCT01934972 Completed Phase 3 A Randomized Controlled Trial of Cognitive Remediation and D-cycloserine for Individuals With Bipolar Disorder March 2013 April 2017
NCT01615367 Completed Phase 1/Phase 2 Nutrition, Exercise, and Wellness Treatment (NEW Tx) for Bipolar Disorder May 21, 2012 February 28, 2017
NCT00001545 Completed Phase 2 Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders May 1996 July 2006
NCT03158805 Completed Phase 2 Saxenda® in Obese or Overweight Patients With Stable Bipolar Disorder (Investigator Initiated) April 26, 2017 January 1, 2023
NCT00562861 Completed Phase 2/Phase 3 Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopram November 2007 July 2014
NCT00538642 Completed N/A Improving Diabetes Risk Factors in Persons With Schizophrenia or Bipolar Disorder by Switching to Ziprasidone August 2007 November 2011
NCT00485771 Completed Phase 4 Olanzapine/Fluoxetine Combination Versus Comparator in the Treatment of Bipolar I Depression November 2003 January 2005
NCT01255982 Completed Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up March 2011 October 2012
NCT00226343 Completed Phase 4 Depakote-ER for Depressive and Bipolar Depression August 2003 August 2006
NCT00139919 Completed Phase 2 Progressively Decreasing Titration Schedules of Bifeprunox in Subjects With Schizophrenia or Bipolar Disorder January 2006 October 2007
NCT00029640 Completed The Treatment of Children and Adolescents With Treatment-Resistant Depression January 2002 March 2004
NCT02129790 Completed N/A Mentalization-Based Therapy to Prevent Suicidal Behavior in Adolescents With Bipolar Disorder January 2014 September 1, 2018
NCT00057135 Completed N/A Improving Antipsychotic Adherence Among Patients With Serious Mental Illness November 2002 September 2006
NCT02703363 Completed Phase 3 Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression August 2016 December 2018
NCT02323763 Completed An fMRI Study on Temporal Discounting in Bipolar Disorder July 14, 2014 August 29, 2016
NCT00208195 Completed Phase 4 Depakote ER Therapy for Mania Comorbid With Substance Abuse March 2004 November 2007
NCT00550576 Completed Phase 2 Antibodies to Digoxin for Bipolar Disorder October 2007 February 2009
NCT00224510 Completed Phase 3 A Study To Investigate The Antidepressant Effect Of Lamotrigine In Patients With Bipolar Disorder Using Lithium August 2002 September 2006
NCT02413918 Completed Phase 4 Iloperidone in Mixed States of Bipolar Disorder April 2012 April 2015
NCT01083823 Completed N/A Calling for Care: Cell Phones for Mood Telemetry in Teens March 2010 April 2012
NCT00026585 Completed Phase 2 Examination of Tamoxifen in Acute Mania in Patients With Bipolar I Disorder November 9, 2001 November 2, 2007
NCT00460226 Completed Lamictal Bipolar Observational Study March 2007 December 2007
NCT02456896 Completed Phase 4 Effect of Oxcarbazepine on Serum Brain Derived Neurotrophic Factor (BDNF) in Bipolar Disorder June 2015 December 2015
NCT00391235 Completed White Matter in Pediatric Bipolar Disorder: A DTI Study September 2005 October 2008
NCT02188732 Completed N/A Self-Management Training and Automated Telehealth to Improve SMI Health Outcomes January 2015 July 31, 2021
NCT00854737 Completed Phase 2 Cytidine and Omega-3 Fatty Acids in Bipolar Disorder July 2004 July 2010
NCT00844974 Completed N/A Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive Symptoms December 2007 December 2012
NCT00176228 Completed Phase 2 Lamotrigine Monotherapy in Pediatric Bipolar Disorder February 2004 January 2008
NCT02037581 Completed N/A Integrated Care Including Assertive Community Treatment in Early Psychosis June 2011 April 2015
NCT01065597 Completed Phase 1 Nonconvulsive Electrotherapy: a Proof-of-concept Trial May 2010 April 2014
NCT01528839 Completed Phase 2/Phase 3 Supraphysiological Doses of Levothyroxine as Adjunctive Therapy in Bipolar Depression March 2004 August 2008
NCT00000439 Completed Phase 2 Drug Treatment for Alcoholics With Bipolar Disorder October 2000 August 2003
NCT00448578 Completed Phase 3 Efficacy and Safety of Seroquel and Lithium as Monotherapy in Acute Mania Treatment in Bipolar Disorder Patients August 2005 June 2006
NCT00067262 Completed Phase 3 An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents March 2003
NCT01202604 Completed A Study Evaluating the Efficacy of Administered Maintenance Treatments in Bipolar Disorder I and II. September 2010 December 2011
NCT03750305 Completed N/A Evaluating the Effectiveness of Imagery Focussed Therapy October 1, 2018 December 30, 2020
NCT00208169 Completed Phase 4 Abilify Therapy for Reducing Comorbid Substance Abuse March 2005 June 2007
NCT01392482 Completed IBIS: Italian Burden of Illness on Schizophrenia & Bipolar Disorder July 2011 September 2012
NCT01293825 Completed Phase 4 Ziprasidone Switching in Response to Adherence and Psychotropic-Related Weight Gain Concerns Among Patients With Bipolar Disorder (Zip Ad) January 2011 August 2012
NCT02081287 Completed Phase 1 Inositol Hexaphosphate: A Novel Treatment Strategy for Bipolar Disorder? May 2014 July 30, 2018
NCT00010868 Completed Phase 2 Omega-3 Fatty Acids in Bipolar Disorder July 2000 July 2004
NCT03127176 Completed Dysbiosis in Bipolar Disorder October 1, 2019 June 30, 2021
NCT01979133 Completed Phase 3 Study of Icariin for Bipolar Disorder and Co-Occurring Substance Use Disorders October 2013 June 2015
NCT01526395 Completed N/A Decreasing the Use of Unmodified Electroconvulsive Therapy (ECT) in an Indian Hospital August 2011 April 2012
NCT00188643 Completed Phase 4 Venlafaxine Versus Lamotrigine in the Treatment of Bipolar I/II Depression January 2002 January 2007
NCT01176825 Completed Phase 1 Cognitive-Behavior Therapy for Young Adults With Bipolar Disorder September 2007 November 2011
NCT00227123 Completed N/A A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence October 2002 November 2006
NCT01644747 Completed Phase 2 tDCS as an add-on Treatment for Resistant Major Depression in Uni- or Bipolar Patients July 19, 2012 March 1, 2022
NCT02870283 Completed Phase 4 Cost- Effectiveness and Quality of Life Assessment in Mood Disorder May 2010 September 2015
NCT01191918 Completed Phase 4 The Efficacy and Safety of AChE Inhibitor Donepezil As Adjunctive Treatment to Mood Stabilizers in Acute Mania May 2005 April 2008
NCT01315509 Completed Dental Status of Patients With Severe Mental Illness April 2011 September 2012
NCT01263548 Completed To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder October 2010 January 2012
NCT00360126 Completed Phase 4 An Open-Label Extension Study Of Lamotrigine In Subjects With Bipolar Disorder October 2005 February 2007
NCT02874833 Completed N/A Exercise for Depression July 2016 February 2018
NCT00510211 Completed An Observational Study of Olanzapine Coated and Orodispersible Tablets Effectiveness in Schizophrenic and Bipolar Outpatients. April 2007 May 2009
NCT01739127 Completed Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI November 2012 February 2016
NCT00277667 Completed Phase 3 Study of Quetiapine Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomanic Symptoms or Mild Manic Symptoms February 2004 December 2007
NCT05111548 Completed N/A Brain Stimulation and Cognitive Training - Efficacy September 8, 2021 May 12, 2023
NCT00490971 Completed Phase 3 A Study to Evaluate the Effectiveness and Safety of Extended-Release (ER) Paliperidone Compared With Placebo in Delaying the Recurrence of Symptoms in Bipolar I Disorder May 2006 April 2010
NCT03403179 Completed N/A Functional Remediation for Bipolar Disorder November 17, 2017 December 20, 2018
NCT00186017 Completed Phase 4 Short Term Rescue Study of Olanzapine July 2005 June 2010
NCT02634372 Completed N/A EMDR vs Supportive Therapy in Relapse Prevention in Traumatized Bipolar Patients March 2016 March 2022
NCT01322113 Completed Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder May 2011 September 2013
NCT04191876 Completed N/A Financial Incentives to Improve Medication Adherence November 1, 2019 March 2, 2022
NCT02087579 Completed Phase 1 Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants February 2014 December 2014
NCT00206544 Completed Phase 2 Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women? January 2004 December 2007
NCT01583569 Completed Complex Dynamic Systems in Mood Disorders November 2011 December 2014
NCT00692133 Completed Spanish Validation of Tool Questionnaire to Assess Patients´Perception About Antipsychotic Treatment March 2008 August 2008
NCT00056277 Completed Phase 3 Bipolar Disorder Study for Men and Women February 27, 2003 December 14, 2005
NCT00119652 Completed Phase 3 Seroquel in Bipolar Depression Versus SSRI May 2005 May 2007
NCT01244854 Completed N/A Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness October 1, 2010 March 6, 2015
NCT06167577 Completed Dysbindin-antipsychotics Psychophamarcogenetics: a Mouse-human Translational Study Towards Personalized Healthcare in Bipolar Disorders November 8, 2018 November 8, 2023
NCT00690859 Completed Predictors of Recurrence in Bipolar Disorder in Spain June 2007 March 2009
NCT00001483 Completed Phase 2 Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression June 1995 May 2002
NCT00192725 Completed N/A Tryptophan Depletion in Acute Mania March 2003 June 2008
NCT02738944 Completed N/A Study to Promote Innovation in Rural Integrated Telepsychiatry November 2016 December 2020
NCT00116077 Completed Dopamine Receptor Imaging in Mood Disorders June 21, 2005 November 12, 2010
NCT00566020 Completed Phase 3 A Clinical Evaluation Of BW430C (Lamotrigine) In Bipolar I Disorder- Long-term Extension Of Study SCA104779 (NCT00550407) - May 2008 October 2010
NCT01786239 Completed N/A Omega-3 Dietary Supplements in Schizophrenia May 2013 September 2015
NCT01804582 Completed N/A The Family VOICE Study May 2013 March 31, 2016
NCT02637401 Completed Group Dialectical Behavioural Therapy for Mood Instability Within Bipolar Disorder: An Open Trial March 2015 June 2016
NCT02294591 Completed Phase 2 NACOS - The Effect of N-acetylcystein for Depressive Symptoms in Patients Suffering From Bipolar Depression November 2014 October 2016
NCT00001544 Completed Genetic Aspects of Neurologic and Psychiatric Disorders April 1996 March 2004
NCT03162380 Completed Occupational Stress and Bipolar Disorder May 22, 2017 June 30, 2018
NCT01133587 Completed N/A Patient Guided Psychiatric Admissions May 2010 December 2013
NCT02663349 Completed N/A Skills Training to Enhance Vocational Outcomes in Veterans With Serious Mental Illness January 2016 July 2019
NCT01992393 Completed N/A Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME) September 2013 September 2015
NCT03959735 Completed N/A High Intensity Interval Training in Severe Mental Illness October 10, 2019 August 30, 2021
NCT02804867 Completed Spot Depression Study March 2016 September 2016
NCT01446406 Completed N/A The MONARCA Project (MONitoring, treAtment and pRediCtion of bipolAr Disorder Episodes) October 2011 August 2014
NCT01237379 Completed Peroxisomal Defects and Familial Risk for Bipolar Disorder October 2010 October 2013
NCT00864370 Completed Bipolar Disorder (BPD) in Pregnancy: Predictors of Morbidity May 2005 June 2013
NCT00237289 Completed Phase 3 Topiramate Versus Placebo as add-on Treatment in Patients With Bipolar Disorder in the Outpatient Setting October 2001 October 2003
NCT00048802 Completed Phase 4 Treatment and Outcome of Early Onset Bipolar Disorder August 2002 August 2006
NCT00852592 Completed Phase 3 Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial May 2009 February 2015
NCT03408873 Completed Phase 4 CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL) April 1, 2018 May 6, 2020
NCT00205699 Completed Phase 4 Metabolic Effects of Antipsychotics in Children April 2006 July 2011
NCT01976975 Completed Brain Mechanisms of Human Motivation October 2013 January 2018
NCT00488618 Completed Phase 2 Study Evaluating Cariprazine (RGH-188) in the Treatment of Patients With Acute Mania June 2007 July 2008
NCT00081380 Completed Phase 3 Efficacy and Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I Disorder March 2004 September 2006
NCT01463111 Completed N/A Decision-Making in Bipolar Disorder May 2011 April 2016
NCT00159744 Completed Phase 3 3-Week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07008) November 30, 2004 April 29, 2006
NCT00067938 Completed Phase 4 Bipolar Study in Adults at Least 18 Years of Age August 2003 August 2004
NCT00265330 Completed Phase 3 Safety and Tolerability of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed) March 2006 January 2008
NCT02005367 Completed N/A A Novel Person-Centered Treatment Component for Substance Use Treatment June 2011 December 2011
NCT01384604 Completed Neurophysiological Studies in Schizophrenia and Psychiatric Disorders December 2007 May 2013
NCT02970721 Completed Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder September 2016 May 2018
NCT00221429 Completed Phase 3 Lithium Versus Divalproex for Treating Pediatric Bipolar Disorder March 2001 February 2015
NCT01410357 Completed N/A Improving Outcomes for Individuals With Serious Mental Illness and Diabetes July 2011 July 2015
NCT03088462 Completed N/A LiveWell: A Mobile Intervention for Bipolar Disorder March 20, 2017 April 10, 2021
NCT00015769 Completed Phase 2 Pilot Study of Levetiracetam (Keppra® (Registered Trademark)) for Bipolar Illness April 2001 April 2003
NCT00060905 Completed Phase 3 An Inpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder January 2003
NCT00376220 Completed Phase 2 A Double-Blind Placebo Controlled Trial of Riluzole in Bipolar Depression May 2004 May 2010
NCT00763230 Completed Phase 2/Phase 3 A Study of Transcranial Direct Current Stimulation (tDCS) to Treat Depression April 2008 January 2011
NCT00993850 Completed Phase 3 Sleep Disturbance and Bipolar Disorder October 2009 July 2012
NCT00060489 Completed Phase 3 Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients With Bipolar Depression September 2002 September 2003
NCT00621842 Completed Phase 3 Lamotrigine for Symptoms of Geriatric Bipolar Depression January 2008 March 2010
NCT02983877 Completed N/A Medication Adherence in Hypertensive Individuals With Bipolar Disorder March 13, 2017 June 28, 2018
NCT02655978 Completed Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder January 2016 October 2019
NCT02494050 Completed N/A Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder June 2015 August 2016
NCT00579280 Completed Phase 4 Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD July 2007 December 2010
NCT01455961 Completed An Epidemiological Registry Study to Evaluate Clinical Practice Treatment in Patients With Bipolar Disorder November 2011 April 2012
NCT02405117 Completed N/A A Mobile Behavioral Monitoring Intervention for Bipolar Disorder January 10, 2014 April 10, 2017
NCT01003132 Completed N/A Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis October 2009 October 2010
NCT00277654 Completed Phase 3 Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder February 2004 March 2009
NCT00074776 Completed Phase 3 Acute Treatment of Bipolar II Depression May 2003 October 2007
NCT00499096 Completed Phase 3 Self-Management Addressing Heart Disease Risk Trial May 2008 November 2012
NCT02594696 Completed N/A Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness November 9, 2015 November 1, 2017
NCT00261443 Completed Phase 4 A Study of Aripiprazole (Abilify) in Patients With Bipolar Mania September 2005 October 2009
NCT00280566 Completed Phase 3 Safety and Maintenance of Effect of Ziprasidone Plus a Mood Stabilizer in Bipolar I Disorder (Manic or Mixed) December 2005 May 2008
NCT02035202 Completed N/A Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness October 2013 May 2017
NCT00543088 Completed Effectiveness of Anti-Psychotic in GPs Setting January 2007 June 2008
NCT00238576 Completed Lamotrigine in the Treatment of Bipolar Disorder in Women of Reproductive Age May 2008 May 2012
NCT00466661 Completed Phase 4 Acamprosate vs. Placebo in Bipolar Alcoholics April 2007 February 2010
NCT03295305 Completed N/A Effect of Action-Based Cognitive Remediation in Patients With Bipolar Disorder January 1, 2017 January 25, 2020
NCT00660712 Completed Evaluation of Patient Characteristics and Treatment Approaches to Patients With Bipolar Disorder in Turkey March 2008 March 2009
NCT01786369 Completed Adherence in Patients Admitted to a Psychiatric Unit for Acute Psychosis: an Analysis of Serum Levels of Antipsychotics. February 2013 April 2015
NCT00552760 Completed Phase 4 Ramelteon for the Treatment of Insomnia and Mood Stability in Patients With Euthymic Bipolar Disorder November 2007 May 2010
NCT02582736 Completed Antipsychotics and Risk of Hyperglycemic Emergencies April 2012 December 2012
NCT03423212 Completed N/A Just Do You Program for Young Adults With Serious Mental IIlness January 31, 2018 March 7, 2020
NCT02326389 Completed N/A Exercise and Cognitive Training May 2015 November 2017
NCT00602537 Completed Phase 4 Antidepressant Therapy in Treating Bipolar Type II Major Depression December 2007 June 2013
NCT00431522 Completed Phase 4 Valproic Acid Sodium Salt in Bipolar Disorder December 2004 October 2006
NCT00616889 Completed Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder May 2006 January 2009
NCT06131866 Completed N/A Acceptance and Commitment Therapy Based Psychoeducation, Meaning of Life and Coping Skills in Bipolar Disorder September 15, 2022 March 20, 2024
NCT00223249 Completed Phase 4 Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence November 2002 August 2004
NCT03863925 Completed Phase 4 Comparison of Propofol Target-Controlled Infusion Anesthesia and Bolus Injection in Electroconvulsive Therapy August 15, 2017 February 2, 2019
NCT02739932 Completed Adolescent Mental Health: Canadian Psychiatric Risk and Outcome Study March 2015 August 2021
NCT00585273 Completed Antipsychotics and Blood Vessel Function September 2007 December 2014
NCT00199966 Completed Phase 4 Safety And Efficacy Study Of Depakote ER To Treat Pediatric Bipolar Disorder December 2003 November 2005
NCT00483548 Completed Phase 3 Adjunctive Ziprasidone in the Treatment of Bipolar I Depression October 2007 December 2008
NCT01168674 Completed Phase 4 Predictors of Response to Augmentation With Ziprasidone (Geodon®) in Major Depressive Disorder February 2010 December 2011
NCT02090634 Completed N/A Texting to Improve Adherence in HIV+ With Bipolar Disorder April 2010 March 2012
NCT00271258 Completed Phase 3 Safety Study of Sodium Divalproate in Bipolar Disorder in Adolescents January 2005 January 2007
NCT00453609 Completed Phase 4 Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI) April 2007 October 2008
NCT00264069 Completed ADH.E.R.E.: Therapeutic ADHerence and Treatment Strategies: A Mental Health Registry June 2005 June 2006
NCT00377299 Completed N/A A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence October 2006 May 2009
NCT01050582 Completed Phase 4 A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children October 2009 July 2011
NCT02448108 Completed N/A Internet Psychotherapy for Bipolar Disorder in Primary Care March 1, 2017 September 30, 2019
NCT01064297 Completed Lamotrigine Pregnancy Registry (LAM05) November 2001 July 2010
NCT00249236 Completed Phase 3 A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder March 2001 December 2001
NCT00094926 Completed Phase 3 A Study of Effectiveness and Safety of Risperdal CONSTA Added to Usual Treatment in Patients With Bipolar Disorder Who Have Frequent Mood Episodes. May 2004 February 2007
NCT03075800 Completed N/A Integration of Illness Management and Recovery Within ACT June 7, 2011 March 31, 2015
NCT00338806 Completed N/A Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder November 2006 July 2012
NCT00179062 Completed N/A Effects of Risperidone and Olanzapine on Patients With Schizophrenia, Schizoaffective Disorder, Major Depression or Bipolar Disorder February 2000 June 2007
NCT00195845 Completed Phase 4 A Double-Blind, Placebo-Controlled Study of Galantamine to Improve Cognitive Dysfunction in Bipolar Disorder April 2003 February 2007
NCT02815813 Completed N/A Lifestyle Intervention for Young Adults With Serious Mental Illness July 3, 2017 May 31, 2022
NCT01784341 Completed Circadian Phase in Bipolar Depression: Is it Delayed and Does it Normalize With Remission? August 2011 December 2016
NCT03825640 Completed N/A Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Open Trial January 14, 2019 January 15, 2020
NCT00223197 Completed Phase 4 Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance Abuse February 2004 April 2006
NCT00458094 Completed N/A Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses March 2007 December 2009
NCT01931644 Completed At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions July 2013 April 2024
NCT01126827 Completed N/A Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder January 2010 April 2011
NCT01460290 Completed Phase 4 Asenapine in the Treatment of Older Adults With Bipolar Disorder October 2011 March 2014
NCT00126009 Completed Phase 2 SOLMANIA - Comparison of Valproate-Amisulpride and Valproate-Haloperidol in Bipolar I Patients May 2004
NCT00857584 Completed Phase 3 Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy May 2009 February 2011
NCT00908154 Completed Phase 1 Safety, Tolerability and Pharmacokinetics of Repeat Doses of GSK1014802. May 31, 2008 December 31, 2008
NCT00277212 Completed Phase 4 A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode December 2005 July 2009
NCT00869765 Completed Phase 2 Transcranial Direct Current Stimulation (tDCS) Augmentation by D-Cycloserine as a Treatment for Depression April 2009 September 2010
NCT02374996 Completed Pharmacoepigenetics of Bipolar Disorder Treatment November 2015 September 2017
NCT00106405 Completed Phase 2 An Evaluation of the Safety and Efficacy of Memantine in Patients With Acute Mania Associated With Bipolar I Disorder February 2005 November 2005
NCT02696109 Completed N/A Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial February 2016 November 2018
NCT00025792 Completed Phase 2 Clinical Trial of Pramipexole in Bipolar Depression October 2001 November 2005
NCT00045916 Completed Phase 4 Optimizing Electroconvulsive Therapy for Depression February 2001 December 2006
NCT00043654 Completed Phase 2 Clinical Trial of Mifepristone for Bipolar Depression August 7, 2002 June 25, 2007
NCT00664976 Completed N/A Treatment Resistant Depression in Bipolar Disorder - A Randomized Controlled Trial of Electroconvulsive Therapy April 2008 September 2013
NCT00227968 Completed Phase 4 Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder March 1995 April 2002
NCT00216723 Completed Efficacy and Safety of Aripiprazole in Patients With Schizophrenia or Bipolar Disorder April 2004 December 2009
NCT00571402 Completed Phase 1/Phase 2 Evaluating the Effectiveness of Family-Focused Psychoeducation in Treating Adolescents With Bipolar Disorder July 2001 September 2005
NCT01409096 Completed Phase 4 Study Using Pregnenolone to Treat Bipolar Depression March 2010 November 2011
NCT01188265 Completed Phase 3 Add-on Dextromethorphan in Bipolar Disorders June 2007 June 2011
NCT00221416 Completed Phase 3 An Open-Label Trial of Aripiprazole in Children and Adolescents With Bipolar Disorder June 2005 December 2008
NCT00622739 Completed Phase 4 Ziprasidone in Pediatric Bipolar Disorder February 2007 November 2009
NCT01383967 Completed Phase 1 A Study of LY2979165 in Healthy Subjects July 2011 June 2012
NCT00787930 Completed Bipolar Disorder in Late Life October 2005 December 2011
NCT01339598 Completed Phase 1 Remediation of Cognitive Dysfunction in Euthymic Bipolar Disorder Patients Using Transcranial Direct Current Stimulation (tDCS) September 2011 October 2015
NCT04020289 Completed N/A A Psychoeducational Program "BalancingMySwing" for Patients With Bipolar Disorder August 1, 2015 December 31, 2018
NCT00125931 Completed Phase 2 Effects of Pentazocine on Manic Symptoms September 2005 December 2008
NCT02765100 Completed N/A Depression, Obesity and Inflammatory Markers October 2014 October 2019
NCT01948024 Completed Phase 1 Bio-equivalence Study Between SAPHRIS and Asenapine July 2013 August 2013
NCT00076115 Completed Phase 3 Study to Determine the Effectiveness of Risperidone in Bipolar Disorder in Children and Adolescents December 2003 December 2005
NCT00026832 Completed Examination of Brain Serotonin Receptors in Patients With Mood Disorders October 4, 2001 November 27, 2012
NCT05837351 Completed N/A The CARE (Collaborative Adolescent Running Experience) Project December 5, 2023 April 30, 2024
NCT00314184 Completed Phase 3 Quetiapine Fumarate Bipolar Maintenance Monotherapy March 2005 July 2007
NCT01890356 Completed N/A Maintenance Transcranial Electrical Stimulation for Depression June 2013 February 2018
NCT00671853 Completed Phase 3 Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD) April 2008 March 2011
NCT00257166 Completed Phase 3 Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed) January 2006 July 2007
NCT05127837 Enrolling by invitation N/A CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies June 28, 2022 February 12, 2024
NCT04130529 Enrolling by invitation N/A Better Sleep in Psychiatric Care - Bipolar October 1, 2019 June 2025
NCT04684615 Enrolling by invitation Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen December 28, 2020 July 31, 2024
NCT04202393 Enrolling by invitation N/A Intervention for Comorbid Substance Use and Bipolar Disorders October 1, 2020 August 31, 2024
NCT02827045 Enrolling by invitation Study of a Vestibular Biomarker of Phase in Bipolar Disorder July 2016 October 2024
NCT00762866 Enrolling by invitation Psychiatric Genotype/Phenotype Project Repository September 2008 December 2027
NCT05703412 Enrolling by invitation N/A Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness February 14, 2023 July 31, 2027
NCT06011460 Enrolling by invitation Observation of Clozapine Treatment Safety in Bipolar Disorder. February 23, 2023 June 30, 2027
NCT04209296 Enrolling by invitation Chart Review of Patients Undergoing Ketamine Infusions December 3, 2019 December 2023
NCT05974527 Not yet recruiting Phase 4 Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department September 1, 2023 June 30, 2026
NCT06115200 Not yet recruiting Norwegian Adult Mental Health Registry January 1, 2024 December 31, 2030
NCT06423794 Not yet recruiting Phase 2 BHV-7000 Open-Label Extension Bipolar Mania Study June 2024 April 2026
NCT05802446 Not yet recruiting N/A Neurofeedback for Bipolar Disorder April 2023 August 2025
NCT05705063 Not yet recruiting N/A Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness January 30, 2023 December 30, 2024
NCT05568823 Not yet recruiting N/A Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder November 1, 2022 January 2, 2025
NCT05721196 Not yet recruiting N/A Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria August 1, 2023 July 30, 2024
NCT06384521 Not yet recruiting N/A Lifestyle MIND- Feasibility of Wait-list Control June 2024 May 2025
NCT05866107 Not yet recruiting N/A App and Body Fat Scale in the Management of Overweight Patients October 15, 2023 December 31, 2024
NCT05823805 Not yet recruiting N/A Approaches For ThE pRioritization of Patients in priMAry Care Post-COVID To Reduce Health Inequities (AFTERMATH) March 2024 March 2025
NCT06371352 Not yet recruiting N/A Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression May 2024 May 2027
NCT06204705 Not yet recruiting mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders July 1, 2024 September 30, 2027
NCT05457127 Not yet recruiting N/A Obstructive Sleep Apnea Treatment in Serious Mental Illness January 1, 2024 November 2026
NCT05699525 Not yet recruiting N/A Personalized Mobile Cognitive Behavioral Therapy Application July 2024 January 2025
NCT05300919 Not yet recruiting N/A Bipolar Disorder Measures in Clinical Care June 2023 February 2025
NCT06235177 Not yet recruiting Early Phase 1 Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues July 24, 2024 September 19, 2025
NCT06274567 Not yet recruiting N/A Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder April 1, 2024 March 31, 2029
NCT06328140 Not yet recruiting Sleep Quality, Cognitive Performance, and Computerized Cognitive Training April 15, 2024 April 14, 2026
NCT06226025 Not yet recruiting Phase 2 Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder June 2024 April 2026
NCT06059313 Not yet recruiting Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders October 1, 2023 February 1, 2027
NCT06363981 Not yet recruiting N/A Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression May 2024 April 2027
NCT05725785 Not yet recruiting N/A Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness June 1, 2023 March 31, 2025
NCT05891639 Not yet recruiting A Close Examination of Patient Experiences in Bipolar Disorder Clinical Trials June 2024 June 2026
NCT05674019 Not yet recruiting N/A MOrphometric MRI Analysis of Cortical Sulci: Development of NEurodevelopmental Biomarkers of Bipolar Disorder. January 15, 2023 January 14, 2025
NCT04063384 Recruiting N/A Acute Alcohol Response In Bipolar Disorder: a fMRI Study July 22, 2019 March 31, 2024
NCT05828056 Recruiting Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder March 2, 2020 December 31, 2024
NCT03977909 Recruiting Early Maladaptative Schemas Among Euthymic Patients With Bipolar Disorder in the Versailles FondaMental Advanced Centers of Expertise for Bipolar Disorders Cohort July 1, 2009 December 1, 2024
NCT06229210 Recruiting Phase 3 Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder January 25, 2024 December 2027
NCT00178932 Recruiting N/A Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors November 1998 December 2023
NCT02765880 Recruiting N/A Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders March 16, 2017 September 2025
NCT05870501 Recruiting N/A Synaptic Imaging and Network Activity in Treatment Resistant Depression October 20, 2021 September 11, 2023
NCT02698696 Recruiting N/A Validation of a Cognitive Remediation Program for Bipolar Disorders February 2014 December 2024
NCT00001174 Recruiting Evaluation of the Genetics of Bipolar Disorder August 11, 1994
NCT05427123 Recruiting Children's Bipolar Network Treatment Trial I July 1, 2022 July 1, 2026
NCT04080778 Recruiting N/A Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD) May 14, 2024 December 30, 2025
NCT05064319 Recruiting Phase 2 Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders February 24, 2022 June 30, 2026
NCT05023252 Recruiting N/A Mobile Self-Tracking October 18, 2021 September 30, 2024
NCT05268809 Recruiting N/A Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet? April 21, 2022 February 2025
NCT00024635 Recruiting Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers February 2, 2001
NCT04298450 Recruiting N/A ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention September 21, 2020 December 2025
NCT04184375 Recruiting N/A Cognitive Stimulation for Elderly Bipolar Patients March 4, 2021 September 3, 2025
NCT06384755 Recruiting N/A Honest Open Proud for Psychotic and Bipolar Disorder in Norway April 20, 2024 December 31, 2026
NCT06336616 Recruiting N/A Getting Out of the House: Using Behavioral Activation to Increase Community Participation February 15, 2024 December 2026
NCT05413486 Recruiting Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity April 4, 2022 July 31, 2024
NCT06313918 Recruiting N/A Exercise Therapy in Mental Disorders-study September 27, 2023 September 26, 2026
NCT06002204 Recruiting Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression March 1, 2024 February 2035
NCT03774641 Recruiting A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women December 3, 2018 March 30, 2025
NCT05698589 Recruiting N/A COMpassion for Psychiatric Disorders And Self-Stigma April 3, 2023 March 1, 2028
NCT03915613 Recruiting Phase 1/Phase 2 Brain Insulin Resistance in Mood Disorders October 6, 2021 October 5, 2024
NCT05445466 Recruiting N/A Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation December 16, 2022 August 1, 2024
NCT05317481 Recruiting N/A Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms April 1, 2022 March 31, 2025
NCT05044611 Recruiting Phase 4 AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium January 11, 2023 November 11, 2025
NCT03944447 Recruiting Phase 2 Outcomes Mandate National Integration With Cannabis as Medicine December 1, 2018 December 31, 2025
NCT05778721 Recruiting Psychiatric Co-morbidities and Socio-demographic Characteristics in Patients With Idiopathic Hypersomnia December 16, 2022 June 16, 2024
NCT02878408 Recruiting N/A Immuno-Genetic, Inflammation, Retro-Virus, Environment November 2014 November 2025
NCT05206747 Recruiting N/A Ottawa Sunglasses at Night for Mania Study September 7, 2022 August 2024
NCT05915013 Recruiting Phase 1 Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response September 7, 2023 December 2032
NCT04696471 Recruiting N/A Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder April 6, 2021 September 2025
NCT05723328 Recruiting N/A Music Therapy Advocacy Recording Intervention (MTAR) on Internalized Stigma April 25, 2023 April 24, 2025
NCT04946916 Recruiting N/A Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease October 22, 2021 October 22, 2025
NCT03245593 Recruiting Shared Medical Decision Making in the Prophylactic Treatment of Bipolar Disorder April 24, 2018 December 2025
NCT00201526 Recruiting Bipolar Research And Innovation Network - BRAIN January 2003 January 2030
NCT05627492 Recruiting N/A Pragmatic Patient-oriented Extension Study of Dialectical Behavior Therapy Booster Sessions for Youth With and/or at Familial Risk for Bipolar Disorder November 9, 2022 November 30, 2028
NCT03336918 Recruiting Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder December 7, 2017 December 1, 2025
NCT05859698 Recruiting Phase 4 Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia May 25, 2023 December 2024
NCT04917419 Recruiting N/A Nursing Care of Bipolar Patients With Sleeping Disorders Using Luminotherapy and /or Psychoeducation Program (BIPLUMINO) December 5, 2022 December 2024
NCT04828226 Recruiting Phase 4 Clonidine to Prevent Delirium After Electroconvulsive Therapy. April 27, 2021 May 27, 2025
NCT06419582 Recruiting Phase 2/Phase 3 BHV-7000 Acute Treatment of Bipolar Mania May 28, 2024 April 2025
NCT04436757 Recruiting N/A Self and Body-esteem in Socio-professional Rehabilitation June 22, 2020 June 2023
NCT05786066 Recruiting Phase 2 The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects April 3, 2023 March 2033
NCT06071858 Recruiting N/A Enhanced Coordinated Specialty Care for Early Psychosis February 1, 2024 October 2028
NCT03898297 Recruiting Imaging mGluR5 and Synaptic Density in Psychiatric Disorders January 11, 2017 April 2025
NCT02731612 Recruiting Phase 3 Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients May 8, 2017 March 31, 2025
NCT06176001 Recruiting N/A Group-based Psychoeducation for Relatives of Patients With Bipolar Disorder, a Randomized Controlled Trial April 7, 2022 June 2024
NCT04317859 Recruiting N/A Behavioural Activation Therapy for Bipolar Disorder May 7, 2019 June 1, 2025
NCT06182787 Recruiting Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient May 18, 2022 January 19, 2024
NCT05840861 Recruiting Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders November 5, 2020 September 5, 2023
NCT05380583 Recruiting N/A Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study May 19, 2022 June 30, 2025
NCT04118283 Recruiting N/A Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness March 18, 2021 January 31, 2025
NCT05436613 Recruiting N/A Transcranial Direct Current Stimulation Therapy for Bipolar Depression May 1, 2022 June 30, 2024
NCT06271304 Recruiting N/A Stabilizing Mood and Sleep With Blue Blocking Eyewear in Bipolar Disorder April 5, 2024 June 1, 2026
NCT02727972 Recruiting N/A Examination of Glutamate and mGluR5 in Psychiatric Disorders August 2011 August 2025
NCT05724953 Recruiting Phase 1 Alexithymia Intervention for Suicide October 1, 2023 May 30, 2025
NCT02443636 Recruiting The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry May 2015 January 2025
NCT05603819 Recruiting Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers June 29, 2022 December 31, 2024
NCT04972708 Recruiting Genetics of COVID-19 Risks & Resilience in Bipolar Disorder July 1, 2021 September 30, 2024
NCT05945277 Recruiting N/A Critical Time Intervention-Peer Support July 1, 2023 December 31, 2025
NCT05867849 Recruiting Phase 3 Cannabidiol for Bipolar Depression (CBD-BD) October 15, 2023 December 2030
NCT04230421 Recruiting N/A Effects of Smartphone-based Treatment for Bipolar Disorder - the Smart Bipolar March 1, 2021 July 1, 2026
NCT05529576 Recruiting Phase 4 Multi-factor Model Constraction for Early Warning and Diagnosis of MDD August 23, 2022 December 31, 2023
NCT03601026 Recruiting N/A Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use November 1, 2019 September 1, 2024
NCT04815239 Recruiting N/A Early Intervention for Youth at High Risk for Bipolar Disorder September 1, 2021 April 30, 2026
NCT06424613 Recruiting Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China April 18, 2024 December 31, 2024
NCT06365021 Recruiting N/A ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder May 2024 August 2026
NCT06335875 Recruiting N/A Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones May 2024 March 2027
NCT05954598 Recruiting N/A Effect of Probiotic vs Placebo on Cognition Outcomes in Patients With Bipolar Disorder May 1, 2022 December 2024
NCT06399523 Recruiting N/A A Study to Evaluate the Efficacy of VR for Bipolar Disorder March 4, 2024 March 4, 2025
NCT05877716 Recruiting N/A EPI-MINN: Targeting Cognition and Motivation - National May 30, 2023 July 2025
NCT01980147 Recruiting N/A Skills for Wellness March 22, 2014 June 30, 2024
NCT05625555 Recruiting Phase 3 Predictors of Intravenous Ketamine Response in TRD January 19, 2024 February 2025
NCT06081426 Recruiting N/A Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD) January 12, 2024 January 2027
NCT05247593 Recruiting A Study of Dayingpian Treating Bipolar Disorder August 1, 2022 September 2024
NCT04675593 Recruiting N/A Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Bipolar Disorder March 15, 2021 June 1, 2026
NCT06373016 Recruiting N/A Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder January 26, 2024 February 1, 2027
NCT04716036 Recruiting N/A Familial Risk for Bipolar Disorder and Alcohol Sensitivity May 13, 2021 July 31, 2024
NCT05178966 Recruiting N/A Evaluation of Efficiency of One Day Patient/Caregiver Psychoeducation on the Caregiver's Burden November 9, 2022 May 31, 2024
NCT06134349 Recruiting The Bipolar Lithium Imaging Scan Study. March 13, 2024 January 1, 2027
NCT04004416 Recruiting Phase 4 Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis January 16, 2020 February 28, 2025
NCT06121206 Recruiting N/A Effects of Altitude-like Cognition Training on Neuroplasticity and Cognitive Functions January 1, 2023 June 2025
NCT04127604 Recruiting N/A Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders November 2, 2020 January 1, 2025
NCT06431386 Recruiting N/A Behavioural Activation Therapy and Esketamine for Resistant Depression June 2024 August 2026
NCT05172271 Recruiting N/A Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD November 8, 2022 October 31, 2025
NCT06038955 Recruiting N/A Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum Disorders October 1, 2022 June 1, 2025
NCT06369792 Recruiting PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSION October 20, 2020 December 31, 2024
NCT06282250 Recruiting N/A Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder May 2024 December 2025
NCT05004896 Recruiting Phase 2 Ketamine for Treatment-Resistant Bipolar Disorder July 4, 2022 December 31, 2025
NCT06370988 Recruiting N/A Theta-Burst Stimulation for Bipolar Depression June 2024 May 2029
NCT04664374 Recruiting Characterizing MyMood Patterns of Use January 6, 2020 January 6, 2025
NCT02778256 Recruiting N/A Study of the Effectiveness of Vestibular Stimulation Treatment in the Depressive Phase of Bipolar Disorder June 2016 October 30, 2024
NCT01888627 Recruiting N/A Integrated Care in Psychotic Disorders With Severe Mental Illness May 2007 December 2025
NCT05186337 Recruiting N/A Functional Remediation for Older Adults With Bipolar Disorder March 15, 2023 June 2025
NCT05762887 Recruiting N/A Clinical Evaluation of the Antidepressant Effect of the Use of Probiotics in Bipolar Disorder January 9, 2023 December 30, 2024
NCT06197048 Recruiting N/A Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder September 25, 2023 December 1, 2028
NCT05669703 Recruiting NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder November 3, 2023 July 31, 2026
NCT06093451 Recruiting Phase 4 Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder July 1, 2023 July 1, 2024
NCT05153369 Recruiting N/A Three-level Model of DBT-informed Care for Youth With and/or at Familial Risk for Bipolar Disorder (DB3) November 1, 2021 March 2026
NCT05463562 Recruiting Multimodal Biomarkers of Electroconvulsive Therapy in Severe and Treatment-resistant Depression February 24, 2022 February 23, 2025
NCT05098574 Recruiting Phase 2 Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder November 30, 2022 June 30, 2024
NCT04622150 Recruiting N/A Effectiveness RCT of Customized Adherence Enhancement February 1, 2022 May 1, 2026
NCT05838274 Recruiting N/A Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study July 11, 2023 March 31, 2028
NCT05801562 Recruiting Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic and Imaging Data to Predict Diagnosis and Outcome of Depressed Patients in Order to Enhance Prognosis and Limiting Healthcare Costs. July 14, 2020 February 14, 2025
NCT04284267 Recruiting N/A Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders March 1, 2021 April 30, 2025
NCT06331286 Recruiting N/A The Effect of Dulaglutide as an Adjuvant Therapy on Cognitive Function in Bipolar Disorder Patients With Obesity September 1, 2023 December 31, 2024
NCT05035316 Recruiting Phase 2 Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT) January 20, 2022 December 1, 2024
NCT03217110 Recruiting N/A Cerebellar Stimulation and Cognitive Control November 30, 2017 August 1, 2024
NCT04454073 Recruiting Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder October 29, 2021 May 2025
NCT06101212 Recruiting Predictors of Quality of Life in Bipolar Disorder November 15, 2023 June 1, 2024
NCT04031560 Recruiting N/A Effects of an Integrative Psychological Program in Bipolar Disorder March 25, 2018 December 2024
NCT05223959 Recruiting N/A Culturally Adapted Psychoeducation for Bipolar Disorder in a Low-resource Setting: A Randomized Controlled Trial June 20, 2022 June 2026
NCT05491538 Recruiting N/A Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness December 1, 2022 November 30, 2024
NCT05409794 Recruiting Basal Plasma Lithium Levels and Suicidal Events December 9, 2022 July 9, 2025
NCT04480918 Recruiting University of Iowa Interventional Psychiatry Service Patient Registry November 2, 2020 August 2050
NCT05153382 Recruiting N/A Dialectical Behavior Therapy for Youth With and/or at Familial Risk for Bipolar Disorder November 1, 2021 November 2026
NCT04296604 Recruiting N/A Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations September 2014 September 2024
NCT04229875 Recruiting N/A The CAG Bipolar the CAG Bipolar RCT January 13, 2020 January 13, 2025
NCT05339074 Recruiting Phase 2 Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression August 11, 2022 February 28, 2026
NCT03829787 Recruiting Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder March 27, 2019 September 1, 2024
NCT05837598 Recruiting N/A Adapting the Tumor Board Model for Mental Illness and Cancer May 31, 2023 May 31, 2024
NCT05340686 Recruiting N/A Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression October 26, 2022 April 20, 2027
NCT04664257 Recruiting N/A Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms March 1, 2020 December 2025
NCT05030272 Recruiting N/A Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings September 21, 2021 April 1, 2025
NCT05457465 Recruiting Phase 2 Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder June 1, 2023 June 2025
NCT06129500 Recruiting N/A CBT for Problematic Impulsive Behaviours in Bipolar Disorder: A Case Series / CBT-PIB August 17, 2023 June 24, 2024
NCT05161546 Recruiting N/A Study of Bipolar Disorders and Retinal Electrophysiological Markers January 18, 2022 August 2025
NCT03740139 Suspended N/A The Police-Mental Health Linkage System February 6, 2019 May 31, 2026
NCT02719392 Suspended Phase 4 A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression August 9, 2017 April 2024
NCT02258711 Suspended N/A Self-Monitoring and Psychoeducation in Bipolar Patients With a Smart-phone Application October 2014 November 2020
NCT05186077 Suspended Brain Circuitry Analysis in Bipolar Disorder October 15, 2020 July 31, 2024
NCT02804334 Terminated The Role of Molecules in Blood Cells for Diagnosing Bipolar Disorders June 2016 October 2018
NCT02355366 Terminated N/A Family Focused Therapy for Teens at Risk for Bipolar Disorder April 2015 November 26, 2018
NCT00805493 Terminated Phase 2 Double-Blind Placebo-Controlled Trial of Riluzole in Pediatric Bipolar Disorder November 2008 June 2012
NCT00063362 Terminated Phase 3 Combination Therapy for the Treatment of Bipolar Disorders February 2002 July 2007
NCT01717040 Terminated Phase 4 Pioglitazone for the Treatment of Bipolar Depression September 2012 March 2016
NCT02727127 Terminated Brain Ion Homeostasis, Lithium and Bipolar Disorder September 2015 September 11, 2019
NCT02389712 Terminated Phase 4 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression March 2015 May 23, 2018
NCT03508427 Terminated N/A Toi Même: a Mobile System for Measuring Bipolar Illness April 12, 2018 December 31, 2020
NCT02909504 Terminated Phase 4 Gao NARASD Lithium Study September 2016 November 2018
NCT02882711 Terminated Phase 2 The UTHealth Ketamine Project November 7, 2016 August 16, 2017
NCT00071253 Terminated Phase 4 Depakote Monotherapy, Olanzapine Monotherapy, and Combination Therapy of Depakote Plus Olanzapine in Stable Subjects During the Maintenance Phase of Bipolar Illness July 2003
NCT03092687 Terminated Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core March 21, 2017 August 29, 2019
NCT00483535 Terminated Phase 1 Oral Contraceptive Interaction Study for GW273225 March 7, 2007 November 16, 2007
NCT03310593 Terminated Phase 2/Phase 3 Cannabidiol as an Adjunctive Treatment for Bipolar Depression November 1, 2017 March 24, 2020
NCT01784666 Terminated Phase 2 Adjunctive Isradipine for the Treatment of Bipolar Depression February 2013 April 2014
NCT02075047 Terminated Phase 3 Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder May 23, 2014 May 18, 2020
NCT00181896 Terminated Phase 4 Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder January 2005
NCT00001260 Terminated Brain Tissue Collection for Neuropathological Studies May 29, 1990 June 16, 2017
NCT03768726 Terminated Phase 3 Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder December 21, 2018 July 31, 2020
NCT00767715 Terminated Phase 4 A Study in the Treatment of Acute Mania October 2004 April 2005
NCT01928043 Terminated Phase 2 Adjunctive Curcumin for Symptomatic Adolescents With Bipolar Disorder: Brain and Body Considerations September 2013 March 3, 2017
NCT00054704 Terminated Phase 2 Riluzole to Treat Depression in Bipolar Disorder February 2003 December 2014
NCT00907985 Terminated Phase 1 A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy Subjects May 15, 2009 June 10, 2010
NCT00109577 Terminated Phase 2 Clinical Trial of a Nutritional Supplement in Adults With Bipolar Disorder April 2005 March 2009
NCT01403441 Terminated N/A Radiosurgical Neuromodulation for Refractory Depression July 2010 January 2013
NCT02505022 Terminated Role Functioning Changes NOS January 2016 January 2021
NCT02151331 Terminated N/A Improving Mental Health Outcomes: Building an Adaptive Implementation Strategy August 2014 November 2017
NCT02402738 Terminated N/A Adjunctive Psychotherapy for Perinatal Bipolar Disorder April 2014 March 2018
NCT04778085 Terminated Young People and Illness Management and Recovery (IMR) March 9, 2021 June 30, 2022
NCT01677182 Terminated Phase 3 Safety and Efficacy Study of Ramelteon (TAK-375) Tablets for Sublingual Administration (SL) in Adults With Bipolar 1 Disorder August 2012 September 2014
NCT00005015 Terminated Phase 3 Treatment of Depression in Youth With Bipolar Disorders September 2000
NCT01504659 Terminated Phase 2/Phase 3 Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder July 2012 November 2016
NCT00374543 Terminated Phase 4 Ziprasidone for the Treatment of Generalized Anxiety in Patients With Bipolar Disorder February 2006 November 2008
NCT00732251 Terminated Phase 4 Allopurinol Maintenance Study for Bipolar Disorder August 2008 January 2012
NCT01520350 Terminated Phase 3 Low-Dose Adjunctive Aripiprazole in the Treatment of Bipolar Depression: Double-Blind Placebo-Controlled Pilot Study February 2012 June 2013
NCT02623504 Terminated Phase 4 DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder October 24, 2016 November 1, 2018
NCT00217217 Terminated Phase 3 Low Field Magnetic Stimulation Treatment for Bipolar Depression September 2004 January 2012
NCT02839798 Terminated Phase 2 NeoSync TMS Treatment for Bipolar I Depression May 2016 November 19, 2018
NCT03210480 Terminated Phase 4 SALT Study (Switching to the Administration of Lithium Slow -Release Treatment) March 28, 2017 September 20, 2019
NCT00451542 Terminated Divalproex vs. Lamotrigine for Bipolar Disorder February 1, 2006 February 1, 2008
NCT00585208 Terminated Phase 3 Add-On Ramelteon in Bipolar I Disorder With Clinically Significant Sleep Disturbance December 2007 December 2010
NCT01665950 Terminated Phase 2 Simvastatin Augmentation of Lithium Treatment in Bipolar Depression August 2012 October 2014
NCT00771134 Terminated Phase 2 Efficacy and Safety of Lu AA39959 in Patients With Bipolar Depression December 2008 August 2009
NCT00665444 Terminated N/A Study of Aripiprazole to Reduce Medical Risks in Bipolar Disorder April 2008 August 2009
NCT00288353 Terminated Phase 3 Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes January 2006 December 2008
NCT04231643 Terminated Early Phase 1 Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers September 1, 2021 November 28, 2023
NCT06105294 Terminated N/A Time-Restricted Eating and Bipolar Disorder June 1, 2023 July 31, 2023
NCT03206463 Terminated Phase 1 Cognitive and Psychophysiological Effects of Delta-9-Tetrahydrocannabinol in Bipolar Disorder August 1, 2017 September 29, 2017
NCT00486798 Terminated Phase 3 FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute Psychosis May 2007 August 2007
NCT00575328 Terminated Phase 3 Study of Maca Root to Treat Sexual Dysfunction Associated With the Treatment Regimen for Bipolar Disorder in Females February 26, 2008 April 26, 2010
NCT03562520 Terminated N/A Toward Exercise as Medicine for Adolescents With Bipolar Disorder June 15, 2018 August 21, 2020
NCT02757521 Terminated Early Phase 1 Nitrous TRD Bipolar Depression March 25, 2016 December 6, 2016
NCT03257592 Terminated Phase 1 Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States August 2010 April 2018
NCT04251234 Terminated N/A Light at Night Study October 15, 2020 August 4, 2021
NCT02893371 Terminated Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies September 2016 June 30, 2019
NCT02472483 Terminated N/A Effectiveness of TCC Followed by MBCT and Predictive Factors (Genetic, Clinical and Cognitive) Response September 13, 2012 September 13, 2019
NCT00947791 Terminated Phase 4 Treatment Study of Bipolar Depression July 2009 October 2009
NCT01526148 Terminated Phase 4 Gao Bipolar Spectrum Lithium/Quetiapine Study January 2012 January 2015
NCT00183612 Terminated N/A Determining the Safety and Effectiveness of Olanzapine in Children and Adolescents May 2000 April 2007
NCT01506232 Terminated Brain Activity Flow Patterns Analysis Using Evoked Response Potentials in Youth With ADHD, Bipolar Disorder, or Autism Spectrum Disorders: A Preliminary Study March 2011 November 2012
NCT00229151 Terminated N/A Sleep Deprivation and Advancement of Sleep Period as Treatment for Bipolar Depression. October 2005 December 2011
NCT00464191 Terminated Phase 4 Escitalopram in Bipolar Depression: a Placebo-controlled Study of Acute and Maintenance Treatment April 2006 March 2009
NCT00746252 Terminated N/A Side Effect Study of Antipsychotic Medicines to Treat Childhood Bipolar Disorder June 2008 October 2010
NCT01566370 Terminated Phase 2 Zonisamide for Heavy Drinkers With Bipolar Disorder May 2012 July 2013
NCT01769859 Terminated Systematic Genetic Analysis of Phenomenology and Treatment Response in Mood Disorders January 2013 May 2016
NCT00194064 Terminated Phase 3 Pilot Study Evaluating the Safety and Efficacy of Open-Label Olanzapine July 2002 February 2006
NCT00139074 Terminated Phase 4 Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients July 2005 June 2006
NCT01928446 Terminated Phase 2/Phase 3 Lithium for Suicidal Behavior in Mood Disorders July 8, 2015 August 13, 2019
NCT01467713 Terminated Phase 3 Efficacy and Safety of Ramelteon Sublingual as Adjunctive Therapy for Maintenance Treatment of Bipolar I Disorder December 2011 March 2015
NCT00746421 Terminated Phase 4 Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder January 2010 April 2012
NCT02351869 Terminated Phase 2 Nitrous Oxide as a Putative Novel Dual-Mechanism Treatment for Bipolar Disorder August 2015 June 7, 2020
NCT01663974 Terminated Evaluation of Sub-syndromal Symptoms After Acute Depressive Episode in Bipolar Disorder April 2013 December 2013
NCT00391001 Terminated Phase 1 Taurine in Adolescents With Bipolar Disorder February 2006 August 2007
NCT01113541 Terminated Phase 3 One-Year Trial of Oral Ziprasidone in Bipolar Patients With Metabolic Syndrome July 2010 February 2011
NCT00939887 Terminated Phase 1 A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography) September 2009 December 2009
NCT03299140 Terminated N/A Evaluation of a Prevention Program in Children and Teenagers at High Risk for Bipolar Disorder (Bipokid) June 18, 2014 November 2, 2017
NCT02726659 Terminated Phase 3 Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression May 2016 January 16, 2019
NCT01957501 Terminated Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel July 2013 March 2016
NCT02149823 Terminated Phase 1 Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations September 2013 June 14, 2022
NCT05420792 Unknown status N/A The Effect of Interpersonal Relationships and Social Rhythm Therapy Individuals With Bipolar Disorder August 1, 2021 October 1, 2022
NCT02285608 Unknown status N/A Partnership in Medication Management (PIMM) in Patients With Mood Disorders January 2015 May 2017
NCT02766361 Unknown status Phase 1/Phase 2 Cognitive-Behavioral Rehabilitation for Bipolar Disorder March 2016 December 2023
NCT02665611 Unknown status N/A Remote Monitoring and Support for Patients With Schizophrenia, Schizoaffective or Bipolar Disorder on Adherence February 2016 January 2018
NCT02630888 Unknown status Phase 2 Efficacy of Memantine add-on in the Treatment of Bipolar Disorder (Type I) Nonresponders or Partial Responders Patients August 2014 September 2020
NCT01237158 Unknown status Genetic Association Study Between GAD1 and Reelin Polymorphisms and GABA/Glutamate MRS in Bipolar Disorder Type 1 and Healthy Controls: SPECGENE PROJECT October 2010
NCT03005574 Unknown status N/A Comparing Thinking Skills for Work (TSW)Home Practice Program With Traditional TSW Program January 2017 December 2020
NCT02627404 Unknown status N/A Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders September 2013 September 2018
NCT01938859 Unknown status Phase 4 Algorithm Guided Treatment Strategies for Bipolar Depression June 2012 December 2018
NCT00879307 Unknown status Phase 3 Brain Derived Neurotrophic Factor as a Predictor of Response to Treatment in Bipolar Depression and Mania: 16-weeks Follow-up With Quetiapine XR March 2009 September 2011
NCT00192582 Unknown status N/A AIMHI NT Relapse Prevention Trial July 2005 August 2007
NCT02782910 Unknown status N/A Smartphone-based Ambulatory Assessment of Early Warning Signs January 1, 2017 July 2020
NCT02841345 Unknown status N/A Characterization of Emotional Processing of Information in Bipolar Disorder and Schizophrenic Patients December 2011 February 29, 2020
NCT03633357 Unknown status N/A Imaging 5HT7 Antagonist Effects in Bipolar Disorder August 16, 2018 June 2022
NCT01749124 Unknown status N/A My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness December 2012 June 2017
NCT01583023 Unknown status Phase 4 Using Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Bipolar Depression April 2014 April 2015
NCT02481245 Unknown status Phase 2 BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study September 2015 June 2023
NCT00742638 Unknown status N/A To Evaluate the Efficiency and Safety of Quetiapine Fumarate in the Treatment of Acute Manic Patients With Bipolar Disorder. March 2008 August 2010
NCT04432116 Unknown status N/A Time and Virtual Reality in Schizophrenia and Bipolar Disorder September 2020 December 2023
NCT00335205 Unknown status Phase 4 A Placebo Controlled Trial of the Dopamine D-2 Receptor Agonist Ropinirole in Treatment of 60 Patients With Refractory Bipolar Depression. April 2003
NCT01863628 Unknown status N/A Recognition and Early Intervention on Prodrome in Bipolar Disorders March 2013 December 2015
NCT03062332 Unknown status The Gut Microbiota of Bipolar and Depression January 16, 2020 November 2022
NCT02360267 Unknown status Pediatric Bipolar Registry May 2013 December 2022
NCT04211428 Unknown status A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder March 2, 2020 July 2023
NCT05064995 Unknown status BIPLONG - The Bipolar Disorder in the Longitudinal Course June 13, 2013 June 13, 2022
NCT04091828 Unknown status Assessment of Cognitive Functions in Bipolar Patients October 2019 November 2022
NCT02986490 Unknown status N/A Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs September 2014 December 2017
NCT01570426 Unknown status Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls July 2007 December 2018
NCT01550029 Unknown status N/A Targeted Intervention for Bipolar Smokers July 2010 August 2014
NCT03862209 Unknown status N/A Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health (RECOVER-E) Croatia January 1, 2018 July 1, 2021
NCT01893229 Unknown status Phase 4 Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania September 2013 December 2015
NCT02423499 Unknown status Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder (REMBAU) May 19, 2015 May 26, 2021
NCT04577508 Unknown status N/A A Trial of Functional Remediation in Patients With Bipolar Disorder January 2021 June 2023
NCT03811860 Unknown status N/A Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function February 6, 2019 December 2019
NCT00188838 Unknown status N/A Psychoeducation Versus Cognitive-Behavioral Therapy in Bipolar Disorder July 2002 August 2006
NCT04024553 Unknown status A Genetic Family Cohort Study of Bipolar Disorder in Chinese Han Population March 28, 2019 December 31, 2022
NCT03603561 Unknown status N/A Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression August 1, 2018 July 2020
NCT02793518 Unknown status N/A Mental Time Travel and Identity in Bipolar Disorder Patients May 2013 October 2016
NCT04703972 Unknown status N/A Identification of Predictive Biomarkers of Mood Relapses in Patients With Bipolar Disorder January 13, 2021 June 30, 2022
NCT03595670 Unknown status Illness Representations in Patients With Bipolar Disorders April 11, 2018 October 2020
NCT01501812 Unknown status Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders March 2011 June 2013
NCT04148963 Unknown status Phase 3 A Study of Staccato Loxapine (ADASUVE®) for Inhalation December 1, 2019 August 1, 2020
NCT02252341 Unknown status Phase 4 Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder September 2014 September 2015
NCT00330226 Unknown status Efficacy and Safety of Psychopharmacotherapy in Patients With Schizophrenia or Bipolar Disorders January 2006 December 2012
NCT00225602 Unknown status N/A Assertive Community Treatment in Copenhagen January 2004 May 2006
NCT02597686 Unknown status N/A The STAGE Study for Bipolar Disorder October 2015 September 2016
NCT02036606 Unknown status Racing and Crowded Thoughts in Mood Disorders April 2014 April 2020
NCT01215383 Unknown status The Antiatherogenic Properties of HDL in Psychiatric Patients With and Without Antipsychotic Therapy November 2010
NCT01000402 Unknown status Phase 4 Juvenile Bipolar Disorder Outpatient Program February 2008 November 2014
NCT02451306 Unknown status N/A Effect of Quetiapine on Brain Activity Patterns in Patients With Heightened Risk of Bipolar Disorder June 2015 May 2018
NCT04564573 Unknown status Antidepressant Treatments and Cognitive Function of Bipolar Patients July 1, 2020 October 30, 2022
NCT03972735 Unknown status N/A Assessment of the Effectiveness of the NECT Program February 10, 2020 April 1, 2023
NCT02334904 Unknown status Comparison of Aripiprazole Versus Risperidone on Brain Morphology Using MRI July 2014 June 2016
NCT02562287 Unknown status Phase 4 Clozapine Versus Other Atypical Antipsychotics for Bipolar Disorder October 2015 December 2020
NCT02456545 Unknown status Improving Early Recognition and Intervention in At-risk Stages of Bipolar Disorders June 3, 2015 September 30, 2021
NCT02836054 Unknown status N/A Study of Degenerescence CSF Hallmarks in Older Bipolar Patients November 2013 December 2019
NCT03892473 Unknown status N/A Community-based Mental Health Care for People With Severe and Enduring Mental III Health ( RECOVER-E ) January 1, 2018 June 1, 2022
NCT00879372 Unknown status Phase 3 Efficacy of Adjunctive Tianeptine in the Treatment of Bipolar Depression March 2009 December 2013
NCT04237610 Unknown status Reward and Punishment Sensitivity in Bipolar Disorders February 24, 2020 February 23, 2022
NCT04674059 Unknown status A Descriptive Study on Patients With Bipolar Disorder in Rwanda January 1, 2021 December 31, 2021
NCT02572674 Unknown status N/A Study of Predictor of Mood Relapse in Bipolar Disorders May 2010 December 2017
NCT01954680 Unknown status Phase 1 Retrain Your Brain in Children/Adolescents With Bipolar Disorder: A Pilot Study August 2013 September 2018
NCT04450147 Unknown status N/A Tai Chi/Qigong for Subsyndromal Depression and Cognition in Older Age Bipolar Disorder November 10, 2020 May 2021
NCT03922425 Unknown status N/A Community-based Mental Health Care for People With Severe and Enduring Mental III Health January 1, 2018 June 1, 2022
NCT02106078 Unknown status N/A Internet-Based Interventions for Bipolar Disorder January 2014 June 2016
NCT03541031 Unknown status N/A Micronutrients as Adjunctive Treatment for Bipolar Disorder May 29, 2018 June 30, 2019
NCT02015143 Unknown status A Comprehensive Assessment and Follow up Descriptive Study on Bipolar Disorder January 2012 December 2014
NCT01678989 Unknown status Evaluation of Brain MRI and Clinical Characteristics of Adolescents With Bipolar Disorder and Children of Parents With Bipolar Disorder July 2011 June 2013
NCT03711045 Unknown status An Eye Tracking Study of Affective Disorder Patients With Suicide Risk September 1, 2018 December 31, 2019
NCT05307848 Unknown status Reproductive Function in Women With Bipolar Disorder March 1, 2021 February 28, 2023
NCT03837340 Unknown status N/A Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health January 1, 2018 June 1, 2022
NCT00879632 Unknown status Brain Derived Neurotrophic Factor as a Predictor of Response to Treatment in Bipolar Depression and Mania March 2009 September 2011
NCT03946787 Unknown status N/A EMDR in Adolescents With Bipolar Disorder and History of Trauma February 5, 2019 January 2020
NCT05209217 Unknown status Open Study of the Neurobiological Effects of Intranasal Ketamine in Children and Adults With Bipolar Disorder June 4, 2019 January 15, 2023
NCT04123301 Unknown status N/A Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics. March 8, 2019 May 1, 2021
NCT00325286 Unknown status Phase 4 Open Label Study of Lithium Plus Extended-Release Carbamazepine (ERC-CBZ) for Rapid Cycling Bipolar Disorder May 2006 March 2008
NCT00422331 Unknown status Phase 3 Safety and Efficacy Study of Lithium in Bipolar Disorder January 2007 December 2007
NCT05307042 Unknown status Decline in Renal Concentration Ability in Lithium Treated Patients May 2022 December 2022
NCT00573196 Unknown status Phase 1 Far Infrared Radiation Treatment for Bipolar Condition September 2006 June 2008
NCT03240380 Unknown status N/A Joint Crisis Plans or Crisis Cards for People With Severe Mental Disorders to Reduce Coercion in Psychiatric Care. May 1, 2017 June 30, 2019
NCT03656302 Unknown status Circadian Rhythm Dysregulation in Offspring of Parents With Bipolar Disorder February 11, 2017 June 28, 2020
NCT03353337 Unknown status N/A A Study of Aerobic Exercise for Patients With Bipolar Disorder December 1, 2017 December 31, 2019
NCT04561622 Unknown status Emotional Proactive Processing in Bipolar Disorder October 1, 2020 October 1, 2022
NCT01529905 Unknown status Longitudinal Study of People Presenting for First Treatment of a Mood Disorder June 1999 June 2014
NCT04400630 Unknown status N/A Functionality and Neurocognition in Patients With Bipolar Disorder After a Physical-exercise Program (FINEXT-BD Study) November 5, 2019 December 31, 2022
NCT01182012 Unknown status Phase 4 Reduction of Cardiovascular Risk in Severe Mental Illness August 2010 December 2012
NCT04359628 Unknown status How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups? January 2002 September 2020
NCT05428241 Unknown status N/A Motivational Interviewing in Patients With Bipolar Disorder July 1, 2022 December 25, 2023
NCT05354895 Unknown status N/A Oxygenating the Brain With Laser Therapy May 1, 2022 May 1, 2024
NCT04643210 Unknown status N/A Management of my Bipolarity Intervention in Bipolar Disorder Patients July 30, 2018 December 31, 2022
NCT02420418 Unknown status N/A The Effect of N- Acetylcysteine on Inflammatory and Oxidative Stress Biomarkers July 2015 May 2017
NCT04124744 Unknown status N/A A Pilot Randomised Controlled Trial of a Health Champion Intervention April 2, 2020 May 30, 2022
NCT00837343 Unknown status Phase 4 A Study to Evaluate the Efficacy and Safety of Flexible Dose of Quetiapine Fumarate (Seroquel) Switching From Other Drugs in the Treatment of Acute Manic Patients With Bipolar Disorder December 2008 December 2010
NCT04486092 Unknown status N/A Mood Stabilizer-induced Metabolic Abnormalities in Bipolar Disorder February 2015 July 2021
NCT03088657 Unknown status Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study September 2015 September 2022
NCT02805088 Unknown status N/A Emotions in Schizophrenia and Bipolar Disorders: a Common Vulnerability? February 2014
NCT02476331 Withdrawn N/A A Trial of Cognitive Training in Euthymic Bipolar Disorder August 2015 August 2017
NCT00720395 Withdrawn Identifying Predictors of Bipolar Disorder Relapse During Pregnancy and the Postpartum Period August 2005 July 2011
NCT01932541 Withdrawn Phase 4 Open-Label Study of Latuda for the Treatment of Mania in Children and Adolescents 6-17 Years Old January 2017 July 2018
NCT03629106 Withdrawn N/A Effects of Cannabis Abstinence on Symptomology and Cognition in Bipolar Disorder October 1, 2018 August 31, 2022
NCT01685151 Withdrawn Phase 3 A Safety and Efficacy Study of Ramelteon Tablets for Sublingual Administration (TAK-375SL) in the Maintenance Treatment of Bipolar 1 Disorder September 2012 November 2015
NCT00447096 Withdrawn Phase 2 rTMS for Treatment of Depressed Phase of Bipolar Disorder Type II February 2007 February 2010
NCT01543724 Withdrawn Phase 4 Neural Correlates for Therapeutic Mechanisms of Lithium in Bipolar Disorder June 1, 2015 December 31, 2017
NCT00338273 Withdrawn Phase 3 A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode December 2006 November 2007
NCT01124877 Withdrawn Phase 3 Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder (Manic Or Mixed) July 2010 October 2011
NCT01372722 Withdrawn Phase 2/Phase 3 Deep Brain Stimulation (DBS) for Treatment Resistant Bipolar Disorder May 2010 May 2012
NCT03764683 Withdrawn Phase 4 Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia February 26, 2019 January 6, 2021
NCT00221481 Withdrawn Phase 4 An Evaluation of Divalproex vs. Olanzapine for Alcohol Abuse Relapse Prevention in Patients With Bipolar Disorder March 2006
NCT02238730 Withdrawn N/A Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy September 2014 February 15, 2017
NCT01075126 Withdrawn Phase 4 Safety Study of Depakote Versus Lithium in African Americans With Bipolar Disorder December 2006 December 2006
NCT01211704 Withdrawn Phase 4 Paliperidone Palmitate Efficacy and Safety in Bipolar Disorder Complicated by Alcoholism October 2010 February 2012
NCT02116400 Withdrawn Neuropsychological Characterization of Patients With Bipolar Disorder and a History of Suicide Attempt January 2017 July 2018
NCT00512616 Withdrawn Phase 2 A Glutamate Transporter GLT1, in the Treatment of Bipolar Disorder August 1, 2007 September 15, 2009
NCT02613104 Withdrawn N/A Emotion Recognition Modification for Bipolar Disorder October 2014 October 2018
NCT02811133 Withdrawn Phase 1/Phase 2 Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder August 2023 October 4, 2023
NCT01117220 Withdrawn Phase 3 Safety And Efficacy Of Ziprasidone In Children And Adolescents With Bipolar I Disorder (Manic Or Mixed) (Protocol A1281196) June 2010 April 2011
NCT00934908 Withdrawn N/A Prevention of Weight Gain and Dyslipidemia by Green Tea in Patients Initiating Therapy With Olanzapine March 2009 March 2009
NCT04811404 Withdrawn Phase 4 A PET Study With [11C]PBR-28 and an Experimental Medication, Ethyl Eicosapentaenoic Acid March 19, 2021 July 1, 2022
NCT01557933 Withdrawn Effects of Electroconvulsive Therapy (ECT) in Bipolar Depression April 2011 July 2012
NCT00726154 Withdrawn N/A Pilot Study of the Effects of Circadian Rhythms on the Treatment of Bipolar I Depression. June 2009 June 2009
NCT00801567 Withdrawn N/A Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation June 2010 June 2010
Disase Synonym (Disease Ontology)
Depressive-manic psych.
Exact Synonym (Disease Ontology)
bipolar depression
Exact Synonym (Disease Ontology)
bipolar disorder manic phase
Exact Synonym (Disease Ontology)
Manic Bipolar Affective disorder
Exact Synonym (Disease Ontology)
Manic bipolar I disorder
Exact Synonym (Disease Ontology)
manic depression
Exact Synonym (Disease Ontology)
Manic Depressive disorder
Exact Synonym (Disease Ontology)
manic disorder
Exact Synonym (Disease Ontology)
mixed bipolar disorder
Disase is a (Disease Ontology)
DOID:3324
Cross Reference ID (Disease Ontology)
GARD:10249
Cross Reference ID (Disease Ontology)
ICD10CM:F31
Cross Reference ID (Disease Ontology)
ICD9CM:296.40
Cross Reference ID (Disease Ontology)
ICD9CM:296.60
Cross Reference ID (Disease Ontology)
ICD9CM:296.80
Cross Reference ID (Disease Ontology)
MESH:D001714
Cross Reference ID (Disease Ontology)
NCI:C34423
Cross Reference ID (Disease Ontology)
NCI:C34424
Cross Reference ID (Disease Ontology)
NCI:C34805
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:16506000
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:191627008
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:192355004
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:68569003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0005586
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0005587
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0024713
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0236780