Intervertebral Disc Degeneration

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Information
Disease name
Intervertebral Disc Degeneration
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04594980 Active, not recruiting N/A Minimally Invasive Decompression and Fusion Versus Open for Degenerative Lumbar Stenosis January 20, 2022 February 1, 2025
NCT03028402 Active, not recruiting Adjacent Segment Mechanics in Cervical Arthrodesis Patients April 2016 August 30, 2024
NCT04759105 Active, not recruiting Phase 2 Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD November 17, 2020 December 30, 2024
NCT06155409 Active, not recruiting Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease July 6, 2021 July 31, 2027
NCT01633034 Active, not recruiting Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain January 2011 December 2025
NCT02617563 Active, not recruiting 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2) December 2015 December 2025
NCT01640457 Completed Phase 1/Phase 2 Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine August 2012 June 14, 2021
NCT01944345 Completed Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion Device June 2013 September 2015
NCT02023372 Completed N/A Efficacy Study of NuCel® in Patients Undergoing Fusion of the Lumbar Spine December 2013 August 16, 2019
NCT02351206 Completed Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients January 2010 November 2014
NCT02535000 Completed Phase 4 Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery January 1, 2014 October 30, 2015
NCT02586116 Completed N/A Comparison of nanOss Cervical IBF System to C-Plus PEEK IBF Device With Autograft October 2015 March 2019
NCT04702126 Completed Smoking Effect on Lumbar Intervertebral Disc Degeneration September 1, 2019 February 1, 2020
NCT05110833 Enrolling by invitation Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery May 1, 2020 April 2026
NCT05098431 Enrolling by invitation N/A Comparison of Three Approaches of Electrode Placement to Detect Changes in Motor Evoked Potentials During Spine Surgery July 1, 2022 July 15, 2024
NCT04134910 Not yet recruiting N/A The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration October 1, 2024 February 2, 2026
NCT06349226 Recruiting Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain May 22, 2018 May 21, 2025
NCT03076658 Recruiting N/A Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers September 2016 January 2031
NCT04600544 Recruiting Russian Disc Degeneration Study October 16, 2020 January 19, 2025
NCT05299762 Recruiting A Post Market Surveillance on INFUSE Bone Graft August 10, 2022 August 31, 2025
NCT05648474 Recruiting Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure July 13, 2022 December 31, 2025
NCT05997121 Recruiting Safety and Performance of the Hexanium TLIF System in the Treatment of Degenerative Disc Disease July 9, 2021 October 30, 2027
NCT06342765 Recruiting Safety and Performance of the SpineVision Posterior Fixation Systems in Thoracolumbar Spinal Treatment September 22, 2022 May 30, 2028
NCT02381067 Terminated N/A A Prospective Study of NuCel® in Cervical Spine Fusion March 2015 December 15, 2016
NCT02873182 Unknown status N/A Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study August 2016 August 2018
NCT05066334 Unknown status Phase 2 Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD March 22, 2021 June 9, 2023
NCT02400762 Unknown status Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery October 2013 March 2019
NCT01799616 Unknown status Phase 2 Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease January 2013 March 2015
NCT04727385 Unknown status N/A Intervertebral DXM Gel Injection in Adults With Painful Lumbar Degenerative Disc Disease September 15, 2020 October 2021
NCT03105167 Unknown status N/A Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation May 7, 2018 December 13, 2021
NCT01989481 Unknown status Predicting the Outcome of Total Knee Arthroplasty and Spinal Surgeon November 2013
NCT02998060 Withdrawn N/A Clinical Evidence of Robot Guided vs. Navigated vs. Free Hand Lumbar Spinal Fusion January 1, 2019 May 2019
NCT03908203 Withdrawn N/A Minimally Invasive Surgery Techniques for One-level Degenerative Lumbar Deformities Correction October 1, 2020 April 1, 2022
NCT04408846 Withdrawn N/A Minimally Invasive Surgery Versus Traditional Open Surgery In The Treatment Of Single Level Lumbar Stenosis December 1, 2020 December 1, 2023
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0008419
MedGen concept unique identifier (MedGen Concept name)
C0158266
MedGen unique identifier (MedGen Concept name)
102357
MeSH unique ID (MeSH (Medical Subject Headings))
D055959