Rectal Carcinoma

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Information
Disease name
Rectal Carcinoma
Disease ID
Description
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
FBXW7 4 152,320,544 152,536,063 4
APC 5 112,737,885 112,846,239 4
PIK3CA 3 179,148,357 179,240,093 4
RET 10 43,077,069 43,130,351 2
PDGFRA 4 54,229,293 54,298,245 2
KDR 4 55,078,481 55,125,595 2
KRAS 12 25,205,246 25,250,929 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02465060 Active, not recruiting Phase 2 Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) August 17, 2015 December 31, 2025
NCT01696981 Active, not recruiting N/A Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial) November 16, 1993 March 11, 2025
NCT04713618 Active, not recruiting Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy January 30, 2021 December 31, 2026
NCT02432963 Active, not recruiting Phase 1 Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy June 14, 2016 December 31, 2024
NCT04505553 Active, not recruiting Phase 2 Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer June 1, 2021 September 30, 2024
NCT00682786 Completed Phase 2 Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma October 2002 August 2010
NCT01333709 Completed Phase 2 Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma May 2011 September 2014
NCT01372007 Completed Phase 3 Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma July 2011 December 2014
NCT01751516 Completed PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study October 2012 March 4, 2018
NCT02000050 Completed Phase 2 Phase II Study of Up-front Chemotherapy and Neo-adjuvant Short-course Radiotherapy for Resectable Rectal Carcinoma (COLORE) October 11, 2013 March 31, 2019
NCT02551237 Completed Phase 3 Neoadjuvant Treatment for Advanced Rectal Carcinoma January 7, 2016 June 2022
NCT04205955 Completed Phase 2 Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors February 10, 2020 August 1, 2023
NCT02736942 Enrolling by invitation Phase 3 COLOR III Trial: Transanal vs Laparoscopic TME December 2, 2016 May 2025
NCT06424522 Not yet recruiting Early Phase 1 A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients October 31, 2024 December 31, 2026
NCT04749108 Recruiting Phase 2/Phase 3 Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma November 26, 2021 August 2027
NCT05685680 Recruiting N/A Outcome of Laparoscopic Total Mesorectal Excision Versus Open Technique in Management of Rectal Carcimoma December 20, 2022 December 20, 2023
NCT02797405 Terminated N/A Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay October 2016 March 13, 2020
NCT04066894 Terminated Phase 2 Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study April 12, 2019 September 1, 2022
NCT01111292 Terminated Phase 1/Phase 2 Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia October 2010 September 2014
NCT01459328 Unknown status Phase 3 Resource-Sparing Curative Treatment for Rectal Cancer September 2009
NCT01899547 Unknown status N/A Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum November 12, 2013 June 6, 2023
NCT02770911 Unknown status Phase 3 Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer June 2016 June 2018
NCT02817126 Unknown status N/A Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal Cancer July 10, 2016 December 31, 2023
NCT04078828 Unknown status N/A PR in Endoscopic LAR for Rectal Cancer September 1, 2019 April 1, 2022
NCT01227239 Unknown status Phase 1/Phase 2 Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting September 2010 August 2016
NCT04848311 Unknown status N/A Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253 May 1, 2021 May 1, 2022
NCT02268006 Unknown status Phase 2 IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment January 2014 December 2020