hyperhomocysteinemia

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Information
Disease name
hyperhomocysteinemia
Disease ID
DOID:9279
Description
"An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood." [url:http\://en.wikipedia.org/wiki/Hyperhomocysteinemia]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03631238 Completed The Dual Impact of Homocysteine and Cholesterol on Cognitive Functions January 15, 2018 August 1, 2018
NCT00005338 Completed Homocysteine and Progression of Atherosclerosis August 1991 August 2004
NCT00005482 Completed Homocyst(e)Ine, Vitamin Status, and CVD Risk September 1995 March 1999
NCT00005483 Completed Plasma Homocysteine Distribution in the United States December 1994 July 1999
NCT00317005 Completed Phase 4 Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events April 2003 March 2005
NCT00473200 Completed Phase 1 Effect of S-adenosylmethionine (SAMe) on Blood Levels of Homocysteine August 2009 July 2013
NCT00626223 Completed N/A 5-methyltetrahydrofolate Survival and Inflammation in ESRD Patients January 1998 July 2007
NCT00737126 Completed N/A The Effect of Folic Acid Administration in the Progression of Microalbuminuria January 2004 December 2005
NCT00755664 Completed Phase 3 Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly July 2007 September 2012
NCT01371357 Completed Phase 3 The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers May 2011 December 2011
NCT01391416 Completed Prevalence Of Hyperhomocysteinemia In Thai Chronic Kidney Disease (CKD) Patients June 2010 January 2011
NCT01766310 Completed Phase 4 Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children December 2012 March 2013
NCT00004495 Completed N/A Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis June 1999 September 2000
NCT02392767 Completed N/A Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function October 2014 August 2015
NCT02540642 Completed N/A Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients October 2010 May 2015
NCT06163443 Completed N/A Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms. March 2, 2022 May 1, 2023
NCT02860338 Completed COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE January 2009 December 2015
NCT02961972 Completed N/A Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals January 2015 June 2017
NCT03376490 Completed Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics January 1, 2012 August 31, 2014
NCT03431597 Completed Phase 2 Effectiveness of a Micronutrient Supplement to Lower Plasma Homocysteine MDEG2 Pilot Supplementation Trial April 26, 2018 November 26, 2018
NCT06264570 Recruiting N/A Evaluation of a Genetically Determined Personalized Approach in Prescribing Biologically Active Substances in Patients With Elevated Blood Homocysteine Levels. October 23, 2023 November 30, 2024
NCT03720249 Unknown status N/A Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults With Hyperhomocysteinemia May 20, 2019 December 31, 2022
NCT02817503 Unknown status Phase 4 Feasibility Study of the Intensive Systolic Blood Pressure Control December 2015 December 2016
NCT01871740 Withdrawn Phase 4 CSPPT- Chronic Kidney Diseases Study May 2008 August 2014
Disase is a (Disease Ontology)
DOID:9252
Cross Reference ID (Disease Ontology)
MESH:D020138
Cross Reference ID (Disease Ontology)
MIM:603174
Cross Reference ID (Disease Ontology)
NCI:C84770
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:419503008
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0598608
MedGen concept unique identifier (MedGen Concept name)
C0598608
MedGen unique identifier (MedGen Concept name)
108623
MeSH unique ID (MeSH (Medical Subject Headings))
D020138