Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

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Information
Disease name
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT01697267 Completed Phase 3 Rituximab Vasculitis Maintenance Study April 2013 November 21, 2019
NCT05988021 Completed Phase 1 A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168 December 3, 2015 May 25, 2016
NCT05988008 Completed Phase 1 A Study of CCX168 in Japanese and Caucasian Healthy Adult Males October 23, 2017 September 20, 2018
NCT06004960 Completed Phase 1 A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants October 20, 2014 December 5, 2014
NCT06004947 Completed Phase 1 A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications January 14, 2016 June 10, 2016
NCT04413149 Completed Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease. April 1, 2014 April 1, 2020
NCT04871191 Not yet recruiting Phase 2 Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis March 2023 January 2027
NCT06350110 Not yet recruiting Phase 1/Phase 2 Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) November 10, 2024 December 28, 2025
NCT06226662 Not yet recruiting Phase 2 Study of NM8074 in Patients With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV) June 2025 September 2027
NCT06379646 Not yet recruiting N/A An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease April 22, 2024 April 21, 2026
NCT05969522 Recruiting Phase 4 Stratified Therapy on Pediatric AAGN January 1, 2023 December 31, 2025
NCT03323476 Recruiting Phase 3 Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease February 2, 2018 March 2031
NCT05732402 Recruiting Phase 1/Phase 2 An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney Diseases March 15, 2023 January 2026
NCT06056921 Recruiting Phase 1 Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease August 31, 2023 August 31, 2026
NCT06294236 Recruiting Phase 1 Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) April 29, 2024 March 2028
NCT06316076 Recruiting Phase 1 Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases October 30, 2023 June 2026
NCT02749292 Terminated Phase 4 Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing June 2016 January 31, 2022
NCT02294344 Terminated N/A The Clinical Efficacy of DFPP in Patients With AAGN June 2014 April 2017
NCT02198248 Unknown status Phase 4 Low-dose Glucocorticoid Vasculitis Induction Study October 2014 June 2021
NCT02180126 Unknown status Differing Levels of Positive Anti-Neutrophil Cytoplasm Antibody (ANCA) Test and Their Correlation With Vasculitis or Malignancy or Chronic Inflammation August 2014 January 2015
NCT01275287 Withdrawn Phase 2 Targeting Complement Activation in Antineutrophil Cytoplasmic Autoantibodies (ANCA)-Vasculitis - Eculizumab May 2011 December 2012
NCT01275274 Withdrawn Phase 2 Retinoids in ANCA Small Vessel Vasculitis: Silencing Autoantigens January 2012 December 2013
MeSH unique ID (MeSH (Medical Subject Headings))
D056648