Bicuspid aortic valve

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Information
Disease name
Bicuspid aortic valve
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03474159 Active, not recruiting N/A Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging November 7, 2018 December 31, 2024
NCT01026571 Active, not recruiting Identification of Genetic Causes of Bicuspid Aortic Valve Disease December 2009 December 2030
NCT03635424 Active, not recruiting N/A Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study October 30, 2018 December 2030
NCT00412386 Completed Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve December 2006 March 2012
NCT01760668 Completed Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome February 2013 October 2015
NCT01823432 Completed Genetic Risks for Bicuspid Aortic Valve Disease March 2012 September 19, 2022
NCT01920815 Completed Bicuspid Valve Aortopathy Feasibility Study July 2013 October 4, 2017
NCT02283970 Completed Investigation of Patients With BAV Requiring Valve and/or Aortic Repair (GISSI Outliers VAR) December 2012 July 2017
NCT02679261 Completed Phase 3 Evaluating the Effectiveness of Atorvastatin on the Progression of Aortic Dilatation and Valvular Degeneration in Patients With Bicuspid Aortic Valve June 2016 February 2021
NCT05836363 Completed Fate at Long-term of Mild to Moderate Bicuspid Aortic Valve Disease Left Untreated at the Time of Supracoronary Ascending Aorta Replacement December 4, 2020 December 9, 2020
NCT04083118 Completed Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride April 1, 2019 September 3, 2023
NCT06212050 Enrolling by invitation Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis September 15, 2023 June 30, 2024
NCT06375590 Not yet recruiting NavIIcusp: Bicuspid Aortic Valve Stenosis With Navitor Platform International Experience May 1, 2024 May 1, 2026
NCT05389865 Not yet recruiting Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes August 2023 August 2024
NCT05711693 Not yet recruiting N/A Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV) February 1, 2023 July 1, 2024
NCT03440697 Recruiting Pathogenetic Basis of Aortopathy and Aortic Valve Disease December 10, 2015 December 31, 2030
NCT05708118 Recruiting Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement. January 20, 2023 January 21, 2024
NCT05739253 Recruiting Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement March 22, 2022 March 21, 2025
NCT05818722 Recruiting A Multicentre Retrospective Study on Bicuspid Aortic Valve December 1, 2022 December 1, 2025
NCT06153407 Recruiting Genetic Test Based Risk Prediction of Early Calcific Aortic Valve Disease in Patients With Bicuspid Aortic Valve October 19, 2023 October 2028
NCT03836521 Recruiting Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry August 15, 2016 August 15, 2028
NCT01756222 Recruiting Bicuspid Aortic Valve (BAV) Registry April 2010 December 2040
NCT01390181 Terminated N/A The Effect of Losartan in Bicuspid Aortic Valve Patients September 2011 January 2014
NCT02917525 Unknown status Phase 2 Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI August 2016 December 2019
NCT04817735 Unknown status N/A The CASPER Registry July 1, 2021 March 30, 2023
NCT02899624 Unknown status N/A Whole Exome Sequencing in Bicuspid Aortic Valve Patients January 2014 January 2018
NCT03495050 Unknown status BIVOLUTX: Bicuspid Aortic Stenosis With Evolut Platform International Experience. February 21, 2018 May 2020
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0001647