Muscular Dystrophy, Duchenne
Information
- Disease name
- Muscular Dystrophy, Duchenne
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02369731 | Active, not recruiting | Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | April 30, 2015 | May 30, 2025 | |
| NCT03992430 | Active, not recruiting | Phase 3 | A Study to Compare Safety and Efficacy of a High Dose of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON) | July 13, 2020 | November 30, 2024 |
| NCT05429372 | Active, not recruiting | Phase 2 | Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy | August 8, 2022 | January 3, 2029 |
| NCT04337112 | Approved for marketing | The Expanded Access Use of Viltolarsen in Duchenne Muscular Dystrophy With Confirmed Exon 53 Amenable Mutation | |||
| NCT00102453 | Completed | Phase 1/Phase 2 | Pentoxifylline in Duchenne Muscular Dystrophy | March 2002 | May 2007 |
| NCT00243789 | Completed | Phase 1/Phase 2 | Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy | September 2005 | January 2008 |
| NCT00296621 | Completed | Phase 2 | Effect of Oral Glutamine on Muscle Mass and Function in Duchenne Muscular Dystrophy | February 2006 | November 2007 |
| NCT01027884 | Completed | Phase 3 | Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD) | July 2009 | April 2014 |
| NCT01506518 | Completed | Double Push Acoustic Radiation Force (DP ARF) Ultrasound for Monitoring Degeneration in Duchenne Muscular Dystrophy | January 2012 | May 31, 2020 | |
| NCT01826422 | Completed | N/A | Effect of EPA and DHA in the Inflammation and Metabolic Disorders in DMD/DMB Patients | March 2013 | January 2017 |
| NCT01826487 | Completed | Phase 3 | Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) | March 26, 2013 | August 20, 2015 |
| NCT02195999 | Completed | Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy | December 2013 | March 6, 2019 | |
| NCT02286947 | Completed | Phase 2 | Safety Study of Eteplirsen to Treat Advanced Stage Duchenne Muscular Dystrophy | November 2014 | March 23, 2018 |
| NCT02383511 | Completed | Phase 1 | Modified Diet Trial: A Study of SMT C1100 in Paediatric Patients With DMD Who Follow a Balanced Diet | February 2015 | August 2015 |
| NCT02439216 | Completed | Phase 1/Phase 2 | Phase 1/2 Study in Boys With Duchenne Muscular Dystrophy | April 2016 | August 2019 |
| NCT02710591 | Completed | Phase 1 | Rimeporide in Patients With Duchenne Muscular Dystrophy | March 2016 | February 2018 |
| NCT02834650 | Completed | N/A | Validating Cardiac MRI Biomarkers and Genotype-Phenotype Correlations for DMD | February 1, 2017 | March 30, 2022 |
| NCT03127241 | Completed | N/A | User-centred Assistive System for Arm Functions in Neuromuscular Subjects | June 16, 2017 | November 30, 2019 |
| NCT03179631 | Completed | Phase 3 | Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy | July 6, 2017 | July 25, 2023 |
| NCT03375255 | Completed | Phase 1 | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Dose of SRP-5051 (Vesleteplirsen) in Patients With Duchenne Muscular Dystrophy (DMD) | February 5, 2018 | August 19, 2019 |
| NCT05209087 | Completed | Effects of Parental Influence on Physical Activity Level and Participation in Children With Duchenne Muscular Dystrophy | March 1, 2020 | August 15, 2022 | |
| NCT00018109 | Completed | Phase 3 | A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD) | ||
| NCT00033189 | Completed | Phase 2 | An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy | September 2001 | January 2005 |
| NCT00033813 | Completed | Phase 2 | KUL0401: An Open-label Pilot Study of Oxatomide in Steroid-Naive Duchenne Muscular Dystrophy | January 2002 | |
| NCT03406780 | Completed | Phase 2 | A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy | March 4, 2018 | March 10, 2020 |
| NCT03490214 | Completed | N/A | Non-invasive Imaging of Muscle Structure in Duchenne Muscular Dystrophy Using Multispectral Optoacoustic Tomography | June 1, 2018 | September 1, 2018 |
| NCT03703882 | Completed | Phase 3 | Phase III Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy | October 2, 2018 | September 22, 2020 |
| NCT03769116 | Completed | Phase 1/Phase 2 | A Randomized, Double-blind, Placebo-controlled Study of Delandistrogene Moxeparvovec (SRP-9001) for Duchenne Muscular Dystrophy (DMD) | December 5, 2018 | August 16, 2023 |
| NCT03789734 | Completed | Phase 1 | Safety Study of BLS-M22 in Healthy Volunteers | June 4, 2019 | November 27, 2020 |
| NCT03963453 | Completed | Regular Physical Exercise in Duchenne Muscular Dystrophy | February 1, 2021 | April 30, 2022 | |
| NCT04669847 | Completed | N/A | The Effects of Trunk Exercises on Upper Extremity and Respiratory Functions in DMD | April 7, 2018 | December 6, 2019 |
| NCT00016653 | Completed | Phase 2/Phase 3 | Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy | June 2000 | December 2006 |
| NCT04626674 | Enrolling by invitation | Phase 1 | A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) | November 23, 2020 | July 31, 2026 |
| NCT06147414 | Not yet recruiting | Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders | April 2024 | December 2026 | |
| NCT06363357 | Not yet recruiting | N/A | The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Duchenne Muscular Dystrophy | April 20, 2024 | December 31, 2025 |
| NCT05833633 | Recruiting | Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations | March 18, 2022 | June 30, 2024 | |
| NCT06337669 | Recruiting | Characterization of DupEx2 Duchenne Muscular Dystrophy | January 31, 2022 | January 31, 2025 | |
| NCT05066633 | Recruiting | Phase 3 | The Efficacy and Safety of Metoprolol as add-on Treatment to Standard of Care in Preventing Cardiomyopathy in Patients With DMD | August 18, 2021 | June 30, 2026 |
| NCT05126758 | Recruiting | Phase 3 | A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy | June 22, 2022 | December 2026 |
| NCT02090959 | Terminated | Phase 3 | An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy | March 20, 2014 | June 12, 2018 |
| NCT03675126 | Terminated | Phase 1/Phase 2 | An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen) | December 19, 2018 | August 25, 2021 |
| NCT01865084 | Terminated | Phase 3 | A Study of Tadalafil for Duchenne Muscular Dystrophy | September 2013 | March 2016 |
| NCT03400852 | Terminated | Phase 2 | A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular Dystrophy | July 27, 2018 | February 25, 2020 |
| NCT03777319 | Terminated | Phase 1 | Spironolactone Versus Prednisolone in DMD | December 5, 2018 | November 30, 2021 |
| NCT01918384 | Unknown status | Phase 2 | Phase II Study of NPC-14 (Arbekacin Sulfate) to Explore Safety, Tolerability, and Efficacy in Duchenne Muscular Dystrophy | August 2013 | October 2015 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D020388