Annotation Detail

Information
Associated Genes
TGFB1
Associated Variants
TGFB1 MUTATION
TGFB1 MUTATION
Associated Disease
Degenerative polyarthritis
Source Database
DisGeNET
Description
These results suggest that the Tgf-β1 canonical signaling was activated to induce HtrA1 in the articular chondrocytes of the mouse models of OA.
Pubmed
24135912
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0110730349285
Drugs