cholera
Information
- Disease name
- cholera
- Disease ID
- DOID:1498
- Description
- "A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, leg cramps, circulatory collapse and shock." [url:http\://www.cdc.gov/nczved/divisions/dfbmd/diseases/cholera/#what, url:http\://www.cdc.gov/nczved/divisions/dfbmd/diseases/cholera/technical.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05507229 | Active, not recruiting | Phase 3 | A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131). | February 22, 2022 | October 30, 2022 |
| NCT05453253 | Active, not recruiting | Phase 4 | Immune Response to a Delayed Second Dose of Oral Cholera Vaccine | July 20, 2022 | July 1, 2024 |
| NCT00142272 | Completed | Phase 3 | Single Dose Ciprofloxacin in the Treatment of Childhood Cholera:Randomized Controlled Clinical Trial | May 2001 | July 2002 |
| NCT00226616 | Completed | Phase 3 | Zinc Supplementation in Cholera Patients | November 2000 | July 2002 |
| NCT00229944 | Completed | Phase 3 | Single Dose Azithromycin in the Treatment of Adult Cholera | December 2002 | May 2004 |
| NCT00289224 | Completed | Phase 3 | Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata | July 2006 | May 2013 |
| NCT00349999 | Completed | Protective Immunity to Human Cholera in Bangladesh | June 2008 | December 2012 | |
| NCT00401934 | Completed | Immunity to Human Cholera in Bangladesh | December 11, 2006 | December 31, 2012 | |
| NCT00419133 | Completed | Phase 2 | Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccine | June 2007 | August 2007 |
| NCT00464867 | Completed | N/A | Effect of Probiotic on Immunogenicity of Oral Cholera Vaccine | January 2006 | December 2008 |
| NCT00672308 | Completed | Phase 2 | Efficacy of Benefiber-Added, Reduced-Osmolarity WHO-ORS in the Treatment of Cholera in Adults | May 2003 | August 2006 |
| NCT00709410 | Completed | N/A | Mass Oral Cholera Vaccination in Zanzibar | January 2009 | December 2011 |
| NCT00119197 | Completed | Phase 2 | Safety and Immunogenicity of Oral Cholera Vaccine in Kolkata | August 2005 | July 2006 |
| NCT00741637 | Completed | Phase 2 | Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults | July 2010 | June 2011 |
| NCT01019083 | Completed | Phase 1/Phase 2 | Studies of Immune Responses to Orally Administered Vaccines in Developing Country | February 2008 | December 2010 |
| NCT01233362 | Completed | Phase 2 | Study of Alternative Vaccination Schedule of Oral Cholera Vaccine | December 2010 | February 2013 |
| NCT01339845 | Completed | N/A | Introduction of Cholera Vaccine in Bangladesh | September 2009 | December 2016 |
| NCT01365442 | Completed | Pilot Introduction of Oral Cholera Vaccine in Orissa, India | May 2011 | September 2012 | |
| NCT00741052 | Completed | Phase 3 | Ciprofloxacin Multiple Dose for Adult Cholera | July 2007 | June 2010 |
| NCT00128011 | Completed | Phase 2 | Safety and Immunogenicity of a New Formulation of a Bivalent Killed, Whole-Cell Oral Cholera Vaccine | May 2005 | June 2005 |
| NCT01895855 | Completed | Phase 3 | Safety and Efficacy Challenge Study of Live Oral Cholera Vaccine Candidate,PXVX0200, to Prevent Cholera | September 2013 | November 2014 |
| NCT01949675 | Completed | Phase 4 | A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in the Philippines | March 2014 | August 2015 |
| NCT02027207 | Completed | Phase 3 | Single Dose Oral Cholera Vaccine Study in Dhaka, Bangladesh | December 9, 2012 | December 31, 2017 |
| NCT02094586 | Completed | Phase 3 | A Phase 3 Lot to Lot Consistency Study of Live Oral Cholera Vaccine, PXVX0200 in Healthy Adults | May 2014 | June 2015 |
| NCT02100631 | Completed | Phase 3 | A Study of Live Oral Cholera Vaccine, PXVX200 in Healthy Older Adults | May 2014 | June 2015 |
| NCT02145377 | Completed | Phase 2 | PXVX0200 (CVD103-HgR) vs Shanchol in Mali | July 2014 | March 2015 |
| NCT02434822 | Completed | Phase 3 | A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in Dominican Republic | April 2015 | July 2016 |
| NCT02727855 | Completed | Cholera Vaccine Investment Strategy in Bangladesh | January 1, 2016 | October 31, 2019 | |
| NCT02742558 | Completed | Phase 2 | Safety and Immunogenicity of Locally Manufactured Oral Cholera Vaccine | April 2016 | June 2017 |
| NCT02823899 | Completed | Phase 1/Phase 2 | Safety and Immunogenicity of Locally Manufactured New (HL-OCV) Oral Cholera Vaccine | July 2016 | November 2017 |
| NCT02864433 | Completed | Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control Efforts | October 2012 | March 2017 | |
| NCT02928341 | Completed | N/A | Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo | October 2016 | December 31, 2021 |
| NCT03373669 | Completed | Phase 4 | Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine | November 16, 2017 | December 1, 2020 |
| NCT03998449 | Completed | N/A | Immunogenicity of Cholera Vaccine in Children With IBD | August 30, 2017 | May 1, 2020 |
| NCT04008134 | Completed | N/A | Cholera-Hospital-Based-Intervention-for-7-days | December 4, 2016 | April 26, 2019 |
| NCT04150250 | Completed | Phase 2 | Cholera Anti-Secretory Treatment Trial | November 4, 2019 | July 27, 2020 |
| NCT04760236 | Completed | Phase 3 | Immune Non-Inferiority, Safety and Lot-to-Lot Consistency of Oral Cholera Vaccine-Simplified Compared to Shanchol™ | October 6, 2021 | March 21, 2023 |
| NCT04816552 | Completed | N/A | Water, Sanitation, and Hygiene Mobile Health Messages as an Innovative Tool to Facilitate Behavior Change | March 22, 2021 | November 28, 2021 |
| NCT01524640 | Completed | Phase 4 | Bridging Study for Killed Oral Cholera Vaccine in Ethiopia | December 2012 | August 2013 |
| NCT01579448 | Completed | Phase 4 | Evaluation of a Boosting Regimen With Oral Cholera Vaccine | December 2012 | July 2013 |
| NCT01585181 | Completed | Phase 1 | Safety and Immunogenicity of the Live Oral Cholera Vaccine Candidate PXVX0200 | April 2012 | January 2013 |
| NCT01811771 | Completed | N/A | Oral Cholera Vaccine Delivery in Rural Bangladesh | August 2012 | August 2015 |
| NCT01823939 | Completed | Phase 1 | PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera | May 2013 | December 2014 |
| NCT05771779 | Not yet recruiting | Phase 3 | Co-administration Study of OCV, TCV and MR | October 14, 2023 | May 2025 |
| NCT06455852 | Not yet recruiting | N/A | Correlates of Protection for Cholera | October 1, 2024 | September 30, 2029 |
| NCT03251495 | Recruiting | Phase 2 | Immunologic Responses to a Live Attenuated Oral Cholera Vaccine | August 29, 2017 | June 30, 2025 |
| NCT05814042 | Recruiting | Phase 2/Phase 3 | Next Generation ORS: Controlled Trial Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea | August 21, 2023 | December 2024 |
| NCT05829772 | Recruiting | Impact Study of Cholera Vaccination in Endemic Areas - Seroprevalence | September 20, 2021 | April 2024 | |
| NCT06003816 | Recruiting | N/A | Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI) | October 18, 2023 | November 2025 |
| NCT06104345 | Recruiting | Phase 4 | Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccines | October 2023 | December 2025 |
| NCT04326478 | Recruiting | Phase 2 | Single Dose Azithromycin to Prevent Cholera in Children | October 31, 2021 | May 31, 2026 |
| NCT06193408 | Recruiting | Phase 2 | Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera | February 11, 2024 | June 15, 2024 |
| NCT04853186 | Recruiting | Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance | May 11, 2021 | June 2024 | |
| NCT05166850 | Recruiting | N/A | Preventative Intervention for Cholera for 7 Days | December 22, 2021 | December 31, 2024 |
| NCT05657782 | Recruiting | Phase 1 | First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers | December 12, 2022 | December 1, 2025 |
| NCT05732766 | Recruiting | Phase 3 | To Evaluate Safety of Oral Cholera Vaccine Hillchol® (BBV131) | February 4, 2023 | August 2023 |
| NCT02499172 | Terminated | N/A | Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi | June 2015 | October 30, 2016 |
| NCT00624975 | Terminated | Phase 2 | Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants | November 2008 | July 2012 |
| NCT02502331 | Unknown status | Phase 3 | Safety and Immunogenicity of a New Formulation of Euvichol® | March 2016 | August 2016 |
| NCT00548054 | Unknown status | Phase 2 | Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants | December 2015 | December 2016 |
| NCT01508507 | Unknown status | Effectiveness of a Bivalent Killed Whole Cell Based Oral Cholera Vaccine | March 2013 | March 2014 |
- Disase is a (Disease Ontology)
- DOID:0050338
- Cross Reference ID (Disease Ontology)
- GARD:6043
- Cross Reference ID (Disease Ontology)
- ICD10CM:A00
- Cross Reference ID (Disease Ontology)
- ICD9CM:001
- Cross Reference ID (Disease Ontology)
- MESH:D002771
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:186087007
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0008354
- Exact Synonym (Disease Ontology)
- Cholera - Vibrio cholerae
- Exact Synonym (Disease Ontology)
- Cholera due to Vibrio cholerae
- Exact Synonym (Disease Ontology)
- Vibrio cholerae
- OrphaNumber from OrphaNet (Orphanet)
- 173
- ICD10 preferred id (Insert disease from ICD10)
- D0000003
- ICD10 class code (Insert disease from ICD10)
- A00
- MeSH unique ID (MeSH (Medical Subject Headings))
- D002771