male infertility

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Information
Disease name
male infertility
Disease ID
DOID:12336
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03677011 Completed N/A Andrositol® TEST as Diagnostic Assay to Predict the Fertilization Potential in IVF July 1, 2018 October 31, 2021
NCT00044369 Completed Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele May 2000 April 2005
NCT00012480 Completed Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm August 2002 July 2007
NCT00178516 Completed Vitamin E and Male Infertility June 2004 December 2005
NCT00315029 Completed N/A Patient-Centered Implementation Trial for Single Embryo Transfer November 2006 October 2008
NCT00341120 Completed Genetic Causes of Male Infertility January 2, 2003 August 29, 2012
NCT00481403 Completed Study of Sperm Molecular Factors Implicated in Male Fertility May 2006 December 2016
NCT00548977 Completed Genetic Studies Spermatogenic Failure January 2001 February 2005
NCT00596739 Completed A Study of the Pre- and Post-operative Semen Analyses and Reproductive Hormone Levels of Men Undergoing Weight-reduction Surgery November 2007 November 2009
NCT00756561 Completed HOP-2A - Intratesticular Hormone Levels September 2008 December 2009
NCT03552081 Completed N/A Tobacco and Sperm Genome: Effects of Smoking Cessation October 2, 2018 June 21, 2022
NCT03834831 Completed N/A Impact of Coenzyme Q10 and Selenium on Seminal Fluid and Semen Antioxidant Status June 1, 2018 January 10, 2019
NCT03802864 Completed Phase 4 Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupivacaine February 4, 2019 January 30, 2020
NCT00975117 Completed Phase 3 Spermotrend in the Treatment of Male Infertility September 2009 March 2011
NCT06042738 Completed N/A Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men March 1, 2021 November 1, 2021
NCT01232465 Completed Impact of Sperm DNA Integrity on In Vitro Cycles October 2010 September 2013
NCT05616598 Completed Phase 2/Phase 3 Effect of New Oral Treatment for Hepatitis C Virus on Seminal Parameters March 1, 2022 December 31, 2022
NCT01304927 Completed Phase 2/Phase 3 Vitamin D Supplementation and Male Infertility: The CBG-study a Randomized Clinical Trial February 2011 May 2016
NCT05222841 Completed Phase 2/Phase 3 The Effectiveness of Spermotrend Food Supplement in the Treatment of Male Infertility June 15, 2021 December 15, 2022
NCT01407432 Completed Phase 3 Impact of Folates in the Care of the Male Infertility November 2011 April 2016
NCT01407484 Completed N/A Male Infertility Related With Post Infection Inflammatory Syndrome March 2, 2011 May 14, 2015
NCT01595308 Completed Phase 1 A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers April 2011 May 2012
NCT05110391 Completed Sperm Retrieval Rates in Non-obstructive Azoospermic Men Subjected to Gonadotropin Therapy February 1, 2014 September 15, 2021
NCT01859520 Completed N/A Swim up and Gradient Methods Used in Assisted Reproduction Techniques on DNA Fragmentation of Spermatozoa July 2012 December 2012
NCT01880086 Completed Phase 2 Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration August 2013 November 2017
NCT01895816 Completed Phase 3 Herbal Tonic Fertile Supplement(ZO2C5) June 2012 June 2012
NCT01974947 Completed Metabolic Syndrome and Male Infertility July 18, 2013 January 20, 2016
NCT02006446 Completed Relationship Between Sperm Head Vacuoles and Sperm DNA Alterations in Infertile Men December 2013 January 2017
NCT02025270 Completed Phase 1/Phase 2 MSCs For Treatment of Azoospermic Patients October 15, 2012 December 20, 2022
NCT02061384 Completed Phase 2 RA-2 13-cis Retinoic Acid (Isotretinoin) August 2014 December 2018
NCT04849156 Completed Spermatozoa Morphology Selection by Thermotaxis April 12, 2021 March 9, 2022
NCT02122211 Completed Phase 1 Choline Dehydrogenase and Sperm Function: Effects of Betaine April 2014 July 2016
NCT02166567 Completed N/A Effect of Sorting of Apoptotic Spermatozoa on the Outcome of Assisted Reproduction May 2013 November 2017
NCT02202382 Completed Phase 4 Effects of Korean Red Ginseng on Male Infertility April 2011
NCT02204826 Completed Phase 4 Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study April 2011 December 2013
NCT02268123 Completed Correlating In Vitro Fertilization Outcomes After Euploid Blastocyst Transfer With Sperm DNA Fragmentation October 2014 July 2018
NCT02272439 Completed Endocrine Disrupting Chemicals: Potential Effects on Male and Female Reproductive Health in Saskatchewan March 2012 January 2015
NCT02349945 Completed Phase 2/Phase 3 FSH Receptor Polymorphism p.N680S and Efficacy of FSH Therapy January 2011 December 2015
NCT02421887 Completed Phase 2 Males, Antioxidants, and Infertility Trial December 2015 December 2018
NCT04496232 Completed N/A Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial August 1, 2020 December 1, 2021
NCT02756923 Completed Regulation of Stem Spermatogonia in the Mature Testis April 2012 December 5, 2019
NCT04256668 Completed N/A Human Sperm Epigenetics in Embryonic Development. April 1, 2020 February 29, 2024
NCT04256278 Completed N/A Administration of Antioxidants to Infertile Men and Sperm Quality February 28, 2020 April 29, 2022
NCT02889341 Completed N/A Valuation of Variable Dose of Docosahexanoic Acid for the Improvement of the Parameters of Male Fertility October 22, 2013 March 2017
NCT02931721 Completed Treatment of Severe Male Infertility - Predictive Factors (Imaging) November 1, 2016 July 2023
NCT04178954 Completed Semen Analysis and Insight Into Male Infertility January 1, 2016 September 30, 2019
NCT04177667 Completed N/A Body Mass Index and Age Correlate With Antioxidant Supplementation Effects on Sperm Quality December 1, 2014 November 30, 2017
NCT03181243 Completed N/A The Acceptance, Safety, and Efficacy of MadaJet Versus Needle Injection for Sperm Retrieval in Patients With Azoospermia July 15, 2017 December 25, 2017
NCT03298633 Completed N/A ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility April 4, 2018 March 31, 2023
NCT03960229 Completed N/A The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor May 23, 2019 September 23, 2019
NCT03466229 Completed N/A Impact of Antioxidant Treatment on DNA Fragmentation Index July 1, 2015 December 31, 2016
NCT03850561 Completed N/A Effect of Two Doses of Coenzyme Q10 on Seminal Fluid and Semen Antioxidant Status June 1, 2018 January 25, 2019
NCT06091969 Not yet recruiting Phase 2 Supplementation for Male Subfertility February 2, 2024 February 2, 2025
NCT05792813 Not yet recruiting Early Phase 1 Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility June 2023 December 2024
NCT04704141 Not yet recruiting Relationship of the Microenvironment and Male Fertility June 2023 June 2026
NCT06324071 Recruiting N/A Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility January 8, 2024 April 2025
NCT04585984 Recruiting N/A Effect of Antioxidant Probiotic Administration on Seminal Quality and Reproductive Outcomes. February 5, 2021 May 2025
NCT04959864 Recruiting N/A Efficacy Study of a Food Supplement With Myo-inositol, N-Acetyl-Cystein, Zinc and Vitamins on Sperm DNA Fragmentation July 7, 2021 July 2023
NCT05205733 Recruiting N/A Expanding Fertility Care to Poor and Low Resourced Settings Study May 24, 2022 June 2024
NCT05290558 Recruiting Phase 2 The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial January 7, 2022 December 31, 2024
NCT05302856 Recruiting N/A CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage March 2, 2022 March 2023
NCT05383599 Recruiting Characterization of Sperm Population Following Different Selection Procedures July 16, 2022 August 1, 2023
NCT05479474 Recruiting N/A Platelet Rich Plasma Testis Treatment for Infertile Men January 18, 2023 January 1, 2025
NCT05503862 Recruiting N/A Home Semen Testing in Men Beginning Attempts to Conceive September 9, 2022 October 2025
NCT05966883 Recruiting SpermQT Prospective Observational Trial January 1, 2023 January 1, 2026
NCT06082362 Recruiting Personalized Signature of Chronic Inflammation and Early Aging Predictive of the Comorbidities in Infertile Men June 21, 2023 June 20, 2025
NCT06100432 Recruiting Phase 4 Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males November 11, 2023 November 1, 2024
NCT06147700 Recruiting Identifying Molecular Determinants of Infertility in Men (MODIFY) October 11, 2023 June 30, 2024
NCT06183255 Recruiting "System Medicine" Approach for Prevention Strategies for Comorbidities in Infertile Men January 18, 2021 July 2025
NCT06188936 Recruiting N/A Home Semen Analysis Tests as a Screening Tool for Fertility Patients November 8, 2023 September 2024
NCT06193850 Recruiting Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients February 24, 2015 January 31, 2045
NCT06210568 Recruiting Oxidative Stress and Male Infertility. June 27, 2023 June 30, 2025
NCT06257459 Recruiting N/A Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy January 1, 2023 December 1, 2024
NCT02107521 Terminated N/A IMSI in Couples With Previous Implantation Failures April 2014
NCT00961558 Terminated N/A Canadian Varicocelectomy Initiative (CVI): Effects on Male Fertility and Testicular Function of Varicocelectomy
NCT02605070 Terminated Phase 3 Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia November 2015 June 13, 2017
NCT01856361 Terminated N/A Ramipril for the Treatment of Oligospermia July 2013 June 2016
NCT01255397 Unknown status N/A Proposed Research Protocol For Male Infertility January 2011
NCT01178463 Unknown status Spermatogonial Stem Cells in Azoospermic Patients: a Comparison Between Obstructive and Non-obstructive Azoospermia January 2010 October 2010
NCT03726450 Unknown status N/A Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men November 1, 2018 March 1, 2020
NCT03553927 Unknown status N/A Investigating the Physiological Effects of Weight Loss on Male Fertility May 16, 2018 December 31, 2022
NCT03475199 Unknown status N/A Evaluation of Personalised Support Program Effectiveness in Sperm Quality Improvement February 13, 2018 December 2019
NCT03864198 Unknown status N/A To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility January 20, 2019 April 30, 2019
NCT03307655 Unknown status N/A Relationship Between Nitric Oxide (NO) in Follicular Fluid and Sperm Fertilization Ability September 21, 2017 October 2019
NCT04158765 Unknown status The Impact of Lifestyle on Sperm Telomere Length and Telomerase Activity in Men Undergoing IVF Treatments November 20, 2019 January 2023
NCT03167749 Unknown status Effect of Liver Cirrhosis on Semen Parameters and Reproductive Hormones January 2018 March 2019
NCT03167008 Unknown status Vitamin D Level vs Semen Parameters October 2020 March 2021
NCT04200118 Unknown status Epigenetic and Genetic Effects in Cancer Patients: Analysis Pre and After Treatment November 29, 2019 April 2021
NCT02864329 Unknown status Small RNA Pathways in Mammalian Gametogenesis April 2014 March 2019
NCT04541459 Unknown status Early Phase 1 Validation of New Devices Against Ambient Electromagnetic Radiation September 14, 2020 April 1, 2021
NCT04946565 Unknown status The Impact of Sinopharm COVID-19 Vaccination on Male Fertility July 3, 2021 August 30, 2022
NCT05200663 Unknown status Phase 2 Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility October 15, 2021 October 2022
NCT05203211 Unknown status Use of Testicular Spermatozoa in Non-azoospermic Patients January 1, 2022 April 2, 2022
NCT00119925 Unknown status N/A 'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists" October 2005 May 2009
NCT02062229 Unknown status Oxidative Stress and Lipidomics in Male Infertility February 2012 June 2016
NCT01075334 Unknown status N/A Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles? February 2010 December 2012
NCT02839447 Withdrawn A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0 September 2025 April 2026
NCT01346631 Withdrawn N/A The Paleolithic Diet and Male Factor Infertility May 2011 May 2012
Disase is a (Disease Ontology)
DOID:48
Cross Reference ID (Disease Ontology)
ICD10CM:N46
Cross Reference ID (Disease Ontology)
ICD9CM:606
Cross Reference ID (Disease Ontology)
MESH:D007248
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:155924001
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0021364
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0003251
ICD10 preferred id (Insert disease from ICD10)
D0011379
ICD10 class code (Insert disease from ICD10)
N46