chronic venous insufficiency

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Information
Disease name
chronic venous insufficiency
Disease ID
DOID:0050853
Description
"A venous insufficiency that is characterized by lower extremity swelling, hyperpigmentation, pruritus and venous ulceration caused by blood pooling in the veins." [url:https\://en.wikipedia.org/wiki/Chronic_venous_insufficiency]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04580160 Active, not recruiting N/A Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System November 30, 2020 December 2024
NCT03900234 Completed Prevalence of Chronic Venous Disease in General Population July 1, 2015 August 31, 2015
NCT01432795 Completed Phase 4 Practicability of Gliding Aids for Medical Compression Stockings November 2010 September 2011
NCT04236245 Completed N/A EU Post Market Clinical Follow-Up Study of the Venclose System for Saphenous Vein Incompetence May 11, 2020 August 2, 2021
NCT04897035 Completed N/A A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Dayspring Active Wearable Compression Technology for Treating Lower Extremity Lymphedema June 1, 2021 July 1, 2022
NCT04757766 Completed VAP-PRO-C6. Effectiveness and Tolerability of Venoactive Drugs in Combination Therapy in Patients With CVD (CEAP C6) March 1, 2021 May 31, 2022
NCT04386785 Completed N/A Venclose RF Ablation System for the Treatment of IPVs May 23, 2020 May 13, 2021
NCT01372020 Completed Phase 4 Neuromuscular Electrical Therapy in Venous Ulcers February 2011 November 2011
NCT03893201 Completed A Singapore Venaseal Real World Post-Market Evaluation Study April 11, 2018 January 31, 2020
NCT01501188 Completed Phase 1 Efficacy Study of Kinesio Taping to Treat Muscular and Joint Problems in Chronic Venous Insufficiency September 2008 September 2012
NCT01654016 Completed Phase 4 Study of Antiinflammatory Effects of Detralex (Daflon) August 2012 September 2019
NCT01848210 Completed Phase 4 Efficacy and Safety of Coumarin and Troxerutin in the Symptomatic Treatment of Chronic Venous Insufficiency May 2013 September 2015
NCT01899482 Completed N/A Manual Lymphatic Drainage in Chronic Venous Insufficiency: a Randomized Controlled Trial July 2013 October 2013
NCT02015221 Completed N/A Evaluation of a Dual Action Pneumatic Compression Device: Patient Ease of Use and Comfort November 2013 August 2015
NCT02050061 Completed N/A Chronic Venous Insufficiency; Impact of Compression Stockings on Quality of Life November 2011 October 2012
NCT02215369 Completed N/A SeCure Endovenous Laser Treatment Study January 2015 January 14, 2019
NCT02236338 Completed Phase 4 Radiofrequency Ablation vs Laser Ablation of the Incompetent Greater Saphenous Vein September 2008 August 11, 2016
NCT02346058 Completed Phase 4 Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins October 2013 October 2014
NCT02395302 Completed N/A Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs) December 2014 November 2015
NCT05507346 Completed N/A A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema September 6, 2022 January 9, 2024
NCT05383469 Completed N/A Efficacy of Active Versus Passive Methods in Chronic Venous Insufficiency September 13, 2022 September 2, 2023
NCT05058989 Completed The Evaluation of the Pathophysiology of Varicose Veins in Pregnancy June 1, 2021 December 1, 2022
NCT03104985 Completed N/A LLLT of Trophic Ulcers of Lower Extremities and Chronic Venous Insufficiency May 2013 December 2015
NCT06238791 Completed Plantar Pressure Analysis and Foot Biomechanics in Lipedema and Chronic Venous Disease October 5, 2023 January 24, 2024
NCT03283800 Completed N/A Copper Impact on Venous Insufficiency and Lipodermatosclerosis September 23, 2015 January 9, 2017
NCT04054440 Enrolling by invitation Outpatient Office Based Endovascular Procedures June 20, 2014 May 17, 2024
NCT06175546 Enrolling by invitation N/A Daily Duration of Compression Treatment in Patients With Symptomatic Chronic Venous Disease February 15, 2023 June 15, 2025
NCT05504070 Enrolling by invitation N/A Venclose digiRF System Post Market Study September 8, 2023 June 2027
NCT06232421 Not yet recruiting Phase 2/Phase 3 Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Process June 2024 December 2024
NCT05993650 Not yet recruiting N/A Inspiratory Muscle Training in Chronic Venous Diseases August 2023 August 2024
NCT06418282 Recruiting N/A Clinical Study to Evaluate the Effectiveness and Health Economics of a Novel Portable Non-Pneumatic Active Compression Device (NPCD) for Lymphedema/Phlebolymphedema May 13, 2024 January 31, 2025
NCT03216005 Recruiting N/A Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System November 2, 2017 December 2025
NCT03784131 Recruiting Phase 1 Tissue Engineered Veins in Patients With Chronic Venous Insufficiency December 15, 2021 June 2025
NCT04231942 Recruiting N/A Elastic Compression Stockings and Varicose Veins Recurrence December 16, 2019 December 31, 2025
NCT04253301 Recruiting N/A Feasibility of the InnoVein Valve and Delivery System for Chronic Venous Insufficiency January 15, 2020 January 15, 2027
NCT05051540 Recruiting N/A The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous Insufficiency November 15, 2021 September 1, 2024
NCT05449743 Recruiting N/A Assessment of the Effect of Spa Therapy on the Quality of Life of Patients With Chronic Venous Insufficiency (NEYRAC) July 11, 2022 July 2023
NCT05622500 Recruiting N/A Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease September 3, 2022 May 1, 2026
NCT05625074 Recruiting National Varicose Vein Study - Portugal November 1, 2022 January 31, 2023
NCT05628688 Recruiting A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA) August 8, 2023 August 28, 2024
NCT05662761 Recruiting Assessment of the Relationship Between Severity of Chronic Venous Obstruction and Venous Claudication March 31, 2022 December 30, 2025
NCT05749471 Recruiting Sex Dysfunction and Chronic Venous Disease January 1, 2019 April 30, 2023
NCT05926830 Recruiting N/A Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study October 12, 2023 September 2025
NCT05982405 Recruiting N/A Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency September 15, 2023 December 2024
NCT06196541 Recruiting Respiratory and Physical Functions in Individuals With Chronic Venous Insufficiency December 27, 2023 December 2026
NCT03904602 Terminated N/A EdemaWear to Reduce Edema in Hospitalized Patients With CVI: August 19, 2019 September 15, 2019
NCT02462096 Terminated N/A A Feasibility Study of the ReLeaf Catheter System September 9, 2015 June 5, 2017
NCT02248740 Terminated Phase 4 Radiofrequency Ablation vs. Laser Ablation of the Incompetent Small Saphenous Vein September 2008 March 29, 2017
NCT02662127 Unknown status N/A Effect of Standing, Lying and Stockings on Blood Bio-markers (v.1) April 2016 July 2017
NCT01000909 Unknown status Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins July 2009 July 2010
NCT01477281 Unknown status Phase 3 Study to Evaluate the Efficacy and Tolerability of Venaflon Use in Reducing the Symptoms Caused by Chronic Venous Insufficiency When Compared With Daflon February 2012 August 2012
NCT04794712 Unknown status Evaluation of Pain Associated With Chronic Venous Insufficiency May 15, 2021 May 14, 2022
NCT01574911 Unknown status Validation of a New Method of Limb Volumetry April 2012 December 2015
NCT02927483 Unknown status Phase 3 Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous Insufficiency November 2016 June 2017
NCT03445091 Unknown status N/A Study to Evaluate Impact SANKOM Patent Socks in Patients With CVI February 5, 2018 April 1, 2018
NCT03384355 Unknown status Ecchymosis and Coldness in Patients With Varicose Vein January 2018 December 2018
NCT01321619 Unknown status Phase 3 Efficacy and Tolerability of the Use of Varicell Compared With Daflon July 2011 December 2011
NCT03835559 Unknown status N/A Cyanoacrylate Closure Versus Surgical Stripping for Incompetent Saphenous Veins April 10, 2019 February 1, 2021
NCT04339075 Unknown status Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore October 1, 2019 October 1, 2021
NCT04339088 Unknown status High Intensity Focused Ultrasound in PAtients With Varicose Veins in Singapore March 1, 2022 December 1, 2023
NCT04384315 Unknown status Efficacy and Safety of Endovenous Radio Frequency (EVRF) for Treatment of Varicose Veins in Singapore August 1, 2019 December 1, 2022
NCT03685838 Unknown status N/A Compression Stockings Therapy Following Mechano-Chemical Ablation (Clarivein®) February 13, 2019 October 1, 2022
NCT04424095 Unknown status Venous Disease in Pediatric Population February 1, 2020 October 1, 2020
NCT03562546 Unknown status N/A The Effect of Structured Exercise on Chronic Venous Insufficiency August 1, 2018 February 28, 2019
NCT02559427 Withdrawn N/A SPA Therapy in the Treatment of Sleep Apnea Syndrome October 2016 March 2019
NCT05047302 Withdrawn N/A Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System-Canada October 1, 2022 November 1, 2026