venous insufficiency

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Information
Disease name
venous insufficiency
Disease ID
DOID:10128
Description
"A vein disease that is characterized by impaired flow of blood through the veins." [url:http\://my.clevelandclinic.org/disorders/venous_insufficiency/hic_venous_insufficiency.aspx, url:http\://www.nlm.nih.gov/medlineplus/ency/article/000203.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00841178 Active, not recruiting N/A Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCT October 2005 November 2022
NCT06369207 Active, not recruiting Investigation of the Transmission Pathways of Reflux in Patients With Chronic Venous Insufficiency September 12, 2023 September 2024
NCT05707169 Active, not recruiting N/A Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein January 4, 2023 May 4, 2024
NCT02397226 Active, not recruiting N/A Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery September 1, 2014 December 31, 2026
NCT00348764 Completed Phase 3 ESGVS: Sclerotherapy With Lauromacrogol March 2004 December 2006
NCT00395265 Completed Evaluating the Relationship Between Blood Clotting Disorders, Inflammation, and Obesity in Individuals With Venous Disorders and Post-Thrombotic Syndrome June 2006 December 2011
NCT00565604 Completed N/A Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins October 2007 June 2009
NCT00617825 Completed N/A Feasibility Study of Cryotherapy for Chronic Venous Disorders September 2007 August 2009
NCT00670540 Completed Epidemiology of Thromboembolism Disease: A Cohort Study November 2004 February 2010
NCT00720239 Completed Early Phase 1 Taliderm Dressing for Venous Ulcers February 2008 August 2010
NCT00732823 Completed Phase 2 Compression Device Safety Study July 2005 October 2005
NCT00759434 Completed N/A A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic Value March 2004 August 2009
NCT00762697 Completed Obtaining and Storing Blood Samples and Debridement Samples for Wound Related Research June 2007 April 2012
NCT00835822 Completed Phase 4 Efficacy and Safety of the Use of Venocur Triplex® in Patients With Chronic Venous Insufficiency May 2005
NCT00838500 Completed Phase 3 THERMES ET VEINES: Spa for Prevention of Leg Ulcers May 2008 November 2011
NCT00855179 Completed Phase 3 Assess the Efficacy and Tolerability of Antistax Film-coated Tablets in Patients With Chronic Venous Insufficiency March 2009
NCT00013273 Completed Phase 2 Physical Conditioning in Management of Chronic Venous Insufficiency January 1999 December 2001
NCT00950378 Completed Non-Invasive Management of Chronic Venous Insufficiency July 2009 December 2012
NCT00858130 Completed N/A Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS) March 2009 November 2009
NCT00196443 Completed Phase 2/Phase 3 The Influence of Compression Stockings on Skin's Barrier Function at Patients With Chronic Venous Disease June 2005 July 2005
NCT00292435 Completed Phase 3 Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI) March 2006
NCT00310752 Completed Phase 1/Phase 2 Evaluation of DermStream(tm) - an Irrigation Product for Chronic Wound Management March 2006 December 2006
NCT02191280 Completed Phase 2 Antistax® in Patients With Chronic Venous Insufficiency April 1998
NCT02211898 Completed Phase 3 Clinical Study of BNS003 on Swelling in Legs Due to Venous Reflux July 2004
NCT02324504 Completed N/A Evaluation of Electrocardiographic Guidance in Accurate Peripherally Inserted Central Catheter Placement in Children. January 2016 December 2017
NCT02395302 Completed N/A Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs) December 2014 November 2015
NCT02431819 Completed N/A Evaluation of the Safety of Compressive Socks to Treat Venous Insufficiency in Patients With Peripheral Arterial Disease February 2015 November 2015
NCT02483962 Completed Phase 2 Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency February 2015 August 2015
NCT02498327 Completed Phase 2 The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency January 2015 October 2015
NCT02588911 Completed N/A Radiofrequency Ablation vs Conventional Surgery for Superficial Venous Insufficiency November 2013 October 2015
NCT02621632 Completed Phase 4 SocknLeg - a User Friendly Medical Compression Study of a Modified Application of a Medical Device March 2013 December 2014
NCT02626156 Completed Phase 2 Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence June 1, 2015 March 31, 2020
NCT02689557 Completed N/A VEINEX : Venous Investigations During Exercise January 2016 October 2019
NCT02729688 Completed N/A Effectiveness of a Pressure Indicator Guided and a Conventional Bandaging in Treatment of Venous Leg Ulcer March 2016 March 1, 2017
NCT03283800 Completed N/A Copper Impact on Venous Insufficiency and Lipodermatosclerosis September 23, 2015 January 9, 2017
NCT03471910 Completed Phase 4 Clinical Non-inferiority Study Between Diosmin 600mg & Diosmin + Hesperidin in Symptomatic Chronic Venous Insufficiency June 20, 2017 April 30, 2018
NCT03755180 Completed N/A Exercise Training in Venous Insufficiency November 28, 2018 June 17, 2019
NCT03850496 Completed N/A DESIVI: Dosing of Electrical Stimulation in Venous Insufficiency November 1, 2015 October 31, 2016
NCT04006184 Completed Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation June 14, 2019 August 30, 2019
NCT04461132 Completed N/A The Effect of Manual Lymphatic Drainage September 11, 2018 May 29, 2020
NCT04469361 Completed The Effect of Training on Hemodynamic Factors in Ballet Dancer September 4, 2017 January 5, 2018
NCT05507346 Completed N/A A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema September 6, 2022 January 9, 2024
NCT01298908 Completed N/A Comparison of Treatments in Venous Insufficiency October 2007 December 2015
NCT01367977 Completed Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life May 2011 April 2015
NCT01371760 Completed N/A BRAVE-DREAMS (BRAin VEnous DRainage Exploited Against Multiple Sclerosis) August 2012 December 2015
NCT01415622 Completed N/A Feasibility, Efficacy, and Safety of Venous Ulcer Treatment Using a Hand Plasma Generator (PlasmaDerm) Chronisch venöser Ulzerationen (PlasmaDerm) April 2011 August 2012
NCT01458795 Completed Phase 4 The Fate Of Calf Perforators After Endovenous Laser Ablation Of Saphenous Veins
NCT01509599 Completed Phase 1/Phase 2 Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation August 2011 December 2015
NCT01549860 Completed N/A Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers April 2012 April 2015
NCT01558024 Completed The Effects of Compression Stockings on Pressure Parameters in Patients With Chronic Venous Insufficiency July 2014 April 2016
NCT01701661 Completed N/A Compression Therapy Versus Surgery in the Treatment of Superficial Venous Reflux September 2004 September 2012
NCT01793194 Completed N/A Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings February 2012 August 24, 2014
NCT02051439 Completed N/A The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower Limb January 2012 May 2012
NCT02061254 Completed N/A Transient Elastography DEdicated to Cosmetology And Dermatology (TEDECAD) April 2014 June 2015
NCT02114307 Completed N/A REVITIVE for the Treatment of Patients With Venous Insufficiency March 1, 2014 October 1, 2014
NCT02137499 Completed N/A Venous Insufficiency and Neuromuscular Stimulation August 2013 July 2014
NCT02184234 Completed Phase 4 Tolerability of Antistax® in Patients Suffering From Chronic Venous Insufficiency (CVI) June 2001
NCT02191163 Completed Phase 2 Efficacy of Antistax® in Improving Microcirculation of the Skin in the Leg in Patients Suffering From Chronic Venous Insufficiency April 2002
NCT02191254 Completed Phase 3 Efficacy and Tolerability of Antistax® in Male and Female Patients Suffering From Chronic Venous Insufficiency April 2004
NCT06438133 Not yet recruiting Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs June 2024 December 2025
NCT02280733 Recruiting A Real World, Observational Registry of Chronic Wounds and Ulcers January 2005 January 2026
NCT05633277 Recruiting N/A Outcomes of Sclerotherapy of the Ulcer Bed Compared to a Combination of Ablation and Injections September 30, 2020 March 2024
NCT03250247 Recruiting N/A Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial) July 2, 2018 April 27, 2026
NCT04546750 Recruiting Prospective Cohort Study for Varicose Veins Incidence and Natural Course September 1, 2020 September 2030
NCT06350695 Recruiting N/A The ROle of Compression StocKings in Heart Failure Patients January 17, 2024 January 1, 2026
NCT01079598 Terminated N/A RFS (Radiofrequency Stylet) - Radiofrequency Perforator Vein Treatment Study March 2010 January 2011
NCT02929056 Terminated Phase 4 Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations February 15, 2017 October 29, 2019
NCT03311269 Terminated Phase 2 A Study Evaluating ClariVein With a Sclerosing Agent for the Treatment of Venous Insufficiency September 22, 2017 March 27, 2020
NCT03652025 Unknown status N/A The Effectiveness of Trans-catheter Foam Sclerotherapy of Pelvic and Atypical Lower Limb Varicosities October 15, 2018 June 15, 2019
NCT04215133 Unknown status N/A Inspiratory Muscle Training Versus Calf Muscle on Venous Function July 3, 2019 May 20, 2021
NCT04524793 Unknown status N/A Efficacy and Safety of Endovenous Microwave Ablations for Treatment of Varicose Veins in Singapore May 9, 2020 December 2021
NCT01346553 Unknown status N/A Safety and Efficacy of the External Synchronized Vein Valve (ESVV) in Treatment of Chronic Venous Insufficiency (CVI) June 2011 January 2012
NCT00270972 Unknown status N/A The Evaluation of OrCel for the Treatment of Venous Ulcers September 2005
NCT01110512 Unknown status Phase 3 Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI) October 2010 March 2011
NCT01972633 Unknown status Phase 1/Phase 2 Endoluminale Obliteration Der Stammvene Mit Dem 1470nm Laser Versus VNUS Closure Fast June 2010 April 2014
NCT01646502 Withdrawn N/A Treatment of Chronic Wound Biofilms July 2014 December 2015
NCT02241707 Withdrawn Does Minimal Post-operative Compression Affect the Outcome for Endovenous Ablation in Treating Varicose Vein Patients? August 2014 August 2015
NCT01173419 Withdrawn N/A Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein July 2010 February 2012
NCT01680809 Withdrawn N/A Compliance of Compression Therapy in Healed Venous Ulcerations September 2012 June 2014
Disase is a (Disease Ontology)
DOID:866
Cross Reference ID (Disease Ontology)
ICD9CM:459.81
Cross Reference ID (Disease Ontology)
MESH:D014689
Cross Reference ID (Disease Ontology)
NCI:C127822
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:20696009
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0042485
Exact Synonym (Disease Ontology)
peripheral venous insufficiency
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0005293
MeSH unique ID (MeSH (Medical Subject Headings))
D014689