cerebral amyloid angiopathy
Information
- Disease name
- cerebral amyloid angiopathy
- Disease ID
- DOID:9246
- Description
- "An amyloidosis where amyloid protein progressively deposits in cerebral blood vessel walls with subsequent degenerative vascular changes that usually result in spontaneous cerebral hemorrhage, ischemic lesions and progressive dementia." [url:http\://en.wikipedia.org/wiki/Cerebral_amyloid_angiopathy]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03464344 | Active, not recruiting | N/A | Cortical Superficial Siderosis and Risk of Recurrent Intracerebral Hemorrhage in Cerebral Amyloid Angiopathy. | October 12, 2018 | February 2025 |
| NCT01821118 | Completed | Phase 2 | Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid Angiopathy | June 2013 | September 2015 |
| NCT05565144 | Completed | Brain Hemorrhage and Functional Outcome in Stroke Patients With CAA Features on Pre-thrombolysis MRI Treated With Intravenous Thrombolysis (Thrombolysis in CAA) ( Thromb in CAA ) | October 2, 2022 | April 24, 2023 | |
| NCT05486897 | Completed | Periventricular White Matter Hyperintensities in Cerebral Amyloid Angiopathy and Hypertensive Arteriopathy | September 5, 2022 | December 15, 2023 | |
| NCT03542656 | Completed | Phase 3 | Application of Amyloid PET in Cerebral Amyloid Angiopathy | September 11, 2014 | March 22, 2018 |
| NCT03824197 | Completed | N/A | Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD) | May 7, 2019 | December 31, 2020 |
| NCT05394636 | Completed | Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy | June 1, 2022 | August 31, 2022 | |
| NCT04825808 | Completed | Detailed Clinical and MRI Characteristics in Primary Non-traumatic Convexity Subarachnoid Haemorrhage Elderly Patients. | February 1, 2021 | March 29, 2021 | |
| NCT05082194 | Completed | Balance Eyesight and Muscle Tension in the Cervical Spine in Cerebral Amyloid Angiopathy | February 10, 2020 | October 10, 2020 | |
| NCT06421532 | Not yet recruiting | Phase 2 | Stimulating Amyloid Clearance in Cerebral Amyloid Angiopathy | June 1, 2024 | August 1, 2026 |
| NCT05499169 | Recruiting | Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage | April 3, 2022 | April 3, 2025 | |
| NCT04204642 | Recruiting | SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA) | June 1, 2020 | December 31, 2024 | |
| NCT05680389 | Recruiting | Phase 1/Phase 2 | Antibiotics Against Amyloid Angiopathy | December 2, 2020 | December 2, 2023 |
| NCT05709314 | Recruiting | Phase 2 | A Study of AMDX-2011P in Participants With CAA | April 2024 | December 2024 |
| NCT05734378 | Recruiting | Prognosis of Cerebral Small Vessel Disease | December 1, 2020 | November 30, 2030 | |
| NCT06128824 | Recruiting | High Frequency Imaging in Cerebral Amyloid Angiopathy | March 19, 2019 | March 31, 2026 | |
| NCT06393712 | Recruiting | Phase 2 | A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy | May 2024 | November 2029 |
| NCT04654026 | Unknown status | the Safety and Efficacy of Antiplatelet Therapy in Patients of CAA | February 20, 2021 | October 30, 2023 | |
| NCT04757597 | Unknown status | N/A | Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage | February 24, 2021 | June 1, 2022 |
| NCT04604587 | Unknown status | Phase 3 | MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAA | October 8, 2020 | July 31, 2023 |
| NCT05207475 | Unknown status | N/A | Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA) | January 20, 2022 | January 20, 2022 |
| NCT03969732 | Unknown status | Phase 3 | Multimodal Biomarkers for Diagnosis and Prognosis in CAA | September 27, 2018 | July 31, 2022 |
| NCT02361411 | Unknown status | Methods of Etiological Diagnosis of Cerebral Amyloid Angiopathy | February 2015 | March 2017 | |
| NCT01856699 | Unknown status | Superficial Siderosis in Patients With Suspected Cerebral Amyloid Angiopathy | May 2013 | May 2019 | |
| NCT01382849 | Withdrawn | F-18-AV-45 Uptake, Spot Sign Presence and Cerebral Amyloid Angiopathy (CAA) in Primary Intracranial Hemorrhage (ICH) | August 2011 | August 2012 |
- Disase is a (Disease Ontology)
- DOID:9120
- Cross Reference ID (Disease Ontology)
- MESH:D028243
- Cross Reference ID (Disease Ontology)
- ORDO:85458
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:45639009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0268393
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C1510489
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C1527338
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C1956349
- Exact Synonym (Disease Ontology)
- Cerebral Hemorrhage, Hereditary, with Amyloidosis
- Exact Synonym (Disease Ontology)
- Hereditary Cerebral Hemorrhage with Amyloidosis
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0011970
- MedGen concept unique identifier (MedGen Concept name)
- C0085220
- MedGen unique identifier (MedGen Concept name)
- 38998
- MeSH unique ID (MeSH (Medical Subject Headings))
- D016657