proteinuria
Information
- Disease name
- proteinuria
- Disease ID
- DOID:576
- Description
- "A kidney disease that is characterized by the presence of excess proteins in the urine." [url:https\://en.wikipedia.org/wiki/Proteinuria]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| RRM2B | 8 | 102,204,502 | 102,238,961 | 4 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06460987 | Completed | Study of the Clinical Efficacy and Safety of Finerenone for the Treatment of IGA Nephropathy | December 1, 2022 | March 31, 2024 | |
| NCT00362960 | Completed | Phase 3 | Olmesartan Medoxomil and Diabetic Nephropathy | May 2003 | September 2004 |
| NCT00446862 | Completed | The Fabrazyme® and Arbs and ACE Inhibitor Treatment (FAACET) Study | March 2007 | December 2012 | |
| NCT00493727 | Completed | N/A | Use of Mucomyst to Ameliorate Oxidant Stress in Diabetics With Proteinuria | September 2006 | December 2007 |
| NCT00507494 | Completed | Phase 3 | Influence of Pioglitazone for Renal Transplant Function in Diabetics | July 2007 | September 2009 |
| NCT00524992 | Completed | Evaluation of Albuminuria HIV-Infected Patients | August 29, 2007 | December 24, 2014 | |
| NCT00528385 | Completed | N/A | Optimalization of Nephroprotection Using Agents Inhibiting Renin-Angiotensin-Aldosterone System | March 2005 | |
| NCT00550095 | Completed | Phase 4 | To Assess the Effects of Valsartan on Albuminuria/Proteinuria in Hypertensive Patients With Type 2 Diabetes Mellitus | June 2007 | November 2009 |
| NCT00568178 | Completed | Phase 3 | An Extension Study Designed to Assess Effects of Losartan on Proteinuria in Pediatric Populations (MK-0954-326 AM1,EXT1(AM2)) | June 1, 2007 | March 1, 2011 |
| NCT00572312 | Completed | N/A | Optimalization of Nephroprotection Using Atorvastatin (Sortis) | February 2005 | |
| NCT00572663 | Completed | N/A | Optimalization of Nephroprotection Using N-Acetylcysteine | January 2005 | |
| NCT00654771 | Completed | Comparison of Catheterized and Clean Catch Urine Specimens for Protein/Creatinine Ratio in Preeclampsia Evaluation | July 2005 | June 2006 | |
| NCT00674596 | Completed | Phase 4 | The Effect of Renin Angiotensin System Blockage (RAS) Blockade On PTX3 Levels In Diabetic Patients With Proteinuria | January 2006 | March 2008 |
| NCT00722215 | Completed | Phase 1 | Endothelin Receptor Antagonism in Proteinuric Nephropathy | May 2006 | December 2007 |
| NCT00801463 | Completed | N/A | Prednisone Plus Tripterygium Wilfordii Treatment of Adult Patients With Idiopathic Focal Segmental Glomerulosclerosis | January 2009 | February 2011 |
| NCT00893425 | Completed | Phase 4 | Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria | January 2008 | April 2009 |
| NCT00915200 | Completed | Phase 2 | N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy | October 2009 | April 2016 |
| NCT00921570 | Completed | Phase 4 | The Effects of Renin Angiotensin System Blockage (RAS), Calcium Channel Blocker and Combined Drugs on TWEAK, PTX3 and FMD Levels in Diabetic Proteinuric Patients With Hypertension | February 2008 | May 2009 |
| NCT00935389 | Completed | N/A | Prospective Study of TW in the Treatment of LN Type V With Gross Proteinuria | April 2009 | May 2011 |
| NCT01015937 | Completed | N/A | Effect of Turmeric on Diabetic Nephropathy | March 2008 | August 2009 |
| NCT01029002 | Completed | Phase 3 | The Effects of Vitamin D Repletion in Vitamin D Deficient Patients With Stage 3 and 4 Chronic Kidney Disease | October 2009 | June 2014 |
| NCT01044771 | Completed | N/A | Pilot Study of Raltegravir Switch to Resolve Tenofovir Induced Proteinuria | January 2010 | June 2011 |
| NCT01156428 | Completed | Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease | July 2010 | November 2016 | |
| NCT01219413 | Completed | Phase 4 | Influence of Aliskiren on Proteinuria | March 2009 | September 2010 |
| NCT01265563 | Completed | Phase 2 | N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy | January 2011 | December 2016 |
| NCT01386554 | Completed | Phase 4 | Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients | August 2011 | May 5, 2017 |
| NCT01410994 | Completed | Bariatric Surgery and the Kidney | April 2011 | April 2014 | |
| NCT01436747 | Completed | Phase 3 | Efficacy and Safety of Paricalcitol for Reduction of Proteinuria in Kidney Transplant Recipients | July 2012 | July 2015 |
| NCT01541267 | Completed | Phase 4 | The Effect of Various Types of the Renin-angiotensin-aldosterone System Blockade on Proteinuria | December 2009 | November 2011 |
| NCT01637259 | Completed | Phase 4 | MARCH Renal Substudy | June 2012 | December 2015 |
| NCT01694160 | Completed | Phase 3 | Oral Paricalcitol in Renal Transplant Recipients for Reducing Albuminuria | January 2013 | December 2015 |
| NCT01703234 | Completed | Phase 4 | FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients | January 2008 | April 2009 |
| NCT01827202 | Completed | Phase 4 | RAS Quantification in Patients With Aliskiren or Candesartan | December 2012 | February 2016 |
| NCT01828138 | Completed | N/A | Hypertension and Urine Protease Activity in Preeclampsia | May 2013 | October 2015 |
| NCT01831193 | Completed | Phase 3 | Effect of Oral Supplementation With Curcumin (Turmeric) in Patients With Proteinuric Chronic Kidney Disease | February 2013 | April 2014 |
| NCT01967355 | Completed | N/A | Prolongation of Pregnancy in Preeclampsia by Therapeutic Lipid Apheresis | April 2013 | May 8, 2014 |
| NCT02090608 | Completed | N/A | Paricalcitol in Fabry Disease | March 2012 | December 2013 |
| NCT02226055 | Completed | An Investigation Into the Cardiovascular Risk and Aetiology of CKDu in Sri Lanka | September 2014 | May 1, 2017 | |
| NCT02232763 | Completed | Phase 3 | Efficacy and Safety of Losartan in Pediatric Chronic Kidney Disease With Tubular Proteinuria | September 2014 | September 2016 |
| NCT02282930 | Completed | Phase 3 | Pilot Study of ACTH in the Treatment of Immunoglobulin A (IgA) Nephropathy at High Risk of Progression | March 2015 | June 30, 2018 |
| NCT02327403 | Completed | Phase 2 | Belatacept Conversion in Proteinuric Kidney Transplant Recipients | October 2015 | October 1, 2020 |
| NCT02536638 | Completed | Proteinuria During Acute Pyelonephritis In Pregnancy | July 2015 | July 2016 | |
| NCT02599532 | Completed | Phase 1 | Pharmacokinetics of Apixaban in Nephrotic Syndrome | April 30, 2017 | June 28, 2019 |
| NCT02780414 | Completed | Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers | January 2016 | October 23, 2020 | |
| NCT03190694 | Completed | Phase 2 | Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria | November 12, 2017 | December 1, 2019 |
| NCT03510286 | Completed | Validation of a PrCr Dipstick Diagnostic Test in Ghana | September 30, 2018 | July 30, 2020 | |
| NCT03983551 | Completed | Phase 4 | Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas | March 1, 2016 | February 28, 2018 |
| NCT04059211 | Completed | Sensitivity and Specificity of Urinary Dipstick in Emergency Departments | April 1, 2019 | March 13, 2020 | |
| NCT04534270 | Completed | Phase 4 | Efficacy and Safety of Dapagliflozin in Children With Proteinuria | July 6, 2020 | March 30, 2022 |
| NCT04874753 | Completed | The Effect of COVID-19 Pandemia on Follow up of Patients With Chronic Kidney Disease | November 3, 2020 | January 1, 2021 | |
| NCT05086549 | Completed | An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria | September 29, 2021 | June 5, 2023 | |
| NCT05283057 | Completed | Phase 3 | Empagliflozin in Patients With Glomerulonephritis | February 20, 2020 | September 30, 2021 |
| NCT05314231 | Completed | Phase 1 | Safety and Pharmacokinetic Study of Subcutaneous ALXN1720 in Participants With Proteinuria | June 29, 2022 | May 31, 2023 |
| NCT05716386 | Completed | N/A | Effect of Low Salt and Ckd Progression | February 28, 2023 | August 31, 2023 |
| NCT06339229 | Completed | Postoperative New-onset Proteinuria and Adverse Outcomes. | January 1, 2000 | November 1, 2023 | |
| NCT06374043 | Completed | Phase 4 | Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin. | May 11, 2021 | September 13, 2022 |
| NCT00001959 | Completed | Phase 2 | Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) | December 1999 | October 2008 |
| NCT00067990 | Completed | Phase 4 | Angiotensin II Blockade for Chronic Allograft Nephropathy | December 2002 | June 2011 |
| NCT00106561 | Completed | Phase 2/Phase 3 | Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney | January 2002 | September 2004 |
| NCT00141453 | Completed | Phase 3 | ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial | April 2003 | January 2009 |
| NCT00199927 | Completed | Phase 3 | Statins in Proteinuric Nephropathies | March 2003 | March 2008 |
| NCT00234871 | Completed | Phase 4 | Tarka® vs. Lotrel® in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM) | January 2004 | |
| NCT00241085 | Completed | Phase 4 | Effect of Valsartan on Proteinuria in Patients With Hypertension and Diabetes Mellitus | November 2002 | August 2005 |
| NCT00242346 | Completed | Phase 3 | High Doses of Candesartan Cilexetil on the Reduction of Proteinuria | April 2003 | December 2006 |
| NCT00343577 | Completed | Antiproteinuric Agents and Fabry Disease | January 2001 | December 2006 | |
| NCT02699736 | Enrolling by invitation | EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV | January 1994 | December 2030 | |
| NCT02798042 | Recruiting | Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery? | June 16, 2016 | May 2024 | |
| NCT06088849 | Recruiting | N/A | Maternal Treatment With ACE-inhibitors and Breastfeeding: a Mono-centric Study on the Exposure Through Breast Milk | December 20, 2021 | December 31, 2023 |
| NCT01094327 | Recruiting | Proteinuria in Pre and Post Transplant | February 2008 | December 2024 | |
| NCT05196035 | Recruiting | Phase 3 | A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria | March 28, 2022 | March 11, 2027 |
| NCT02818192 | Recruiting | Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort Study (National iCARE Study) | January 2017 | March 2026 | |
| NCT05457283 | Recruiting | Phase 3 | A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria | November 8, 2022 | September 10, 2028 |
| NCT05753696 | Recruiting | N/A | Azilsartan in Patients With Diabetic Kidney Disease and Hypertension | April 1, 2023 | December 30, 2024 |
| NCT06162546 | Recruiting | ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and Biobank | January 1, 2023 | December 31, 2033 | |
| NCT05759754 | Recruiting | N/A | Effects of Traditional Chinese Medicine (GSJYF) in Children With Inherited Proteinuric Kidney Disease | September 17, 2023 | October 1, 2024 |
| NCT04752293 | Recruiting | Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) | May 19, 2021 | December 2025 | |
| NCT00977977 | Recruiting | Phase 2 | Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy | December 22, 2010 | January 31, 2025 |
| NCT00369538 | Suspended | Phase 4 | Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria | August 2006 | |
| NCT02373241 | Terminated | Phase 2 | Preventing Sickle Cell Kidney Disease | April 2015 | July 2021 |
| NCT01164098 | Terminated | Phase 3 | Rituximab to Prevent Recurrence of Proteinuria | February 2012 | October 2016 |
| NCT00961207 | Terminated | Phase 4 | Triple Blockade of the Renin Angiotensin Aldosterone System in Diabetic (Type 1&2) Proteinuric Patients | August 2009 | September 2012 |
| NCT00001978 | Terminated | Determination of Kidney Function | October 11, 1989 | October 2, 2020 | |
| NCT00856674 | Terminated | Phase 1 | Safety Study of of Intravenous CCL2-LPM in Patients With IgA Nephropathy | March 2009 | June 2010 |
| NCT04051957 | Terminated | Phase 2 | Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury | September 26, 2019 | February 12, 2021 |
| NCT02057523 | Terminated | Phase 4 | Acthar as Rescue Therapy for Transplant Glomerulopathy in Kidney Transplant Recipients | September 2014 | September 2015 |
| NCT00338091 | Terminated | N/A | Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency | January 2002 | May 2006 |
| NCT01804777 | Terminated | Early Phase 1 | Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes | March 2013 | December 2014 |
| NCT00698659 | Terminated | Pharmacodynamic Effects of Anti-Vascular Endothelial Growth Factor Therapy in Patients With Advanced Malignancies | August 2007 | May 2010 | |
| NCT04171778 | Terminated | N/A | Effects of Whole Food, Plant-Based Nutrition on Chronic Kidney Disease With Proteinuria | December 5, 2019 | March 28, 2022 |
| NCT00912834 | Unknown status | Study of Prevalence of Proteinuria, Urinary Tract Infection or Hematuria in Athletes | December 2008 | November 2009 | |
| NCT03019848 | Unknown status | Phase 2 | Effect of Oral Supplementation With Curcumin in Patients With Proteinuric Diabetic Kidney Disease | May 2016 | May 2017 |
| NCT01642979 | Unknown status | Phase 2 | Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria | July 2012 | July 2017 |
| NCT03195023 | Unknown status | Phase 4 | Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01) | June 2015 | December 2022 |
| NCT05241327 | Unknown status | N/A | Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure | January 1, 2022 | May 30, 2023 |
| NCT01760096 | Unknown status | Phase 2 | Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013) | January 2013 | July 2017 |
| NCT01773382 | Unknown status | N/A | The Effects of Weight Reduction in IgA Nephropathy | October 2012 | April 2013 |
| NCT01820832 | Unknown status | Phase 4 | Oral Calcitriol for Reduction of Mild Proteinuria in Patients With CKD | March 2013 | June 2015 |
| NCT03550859 | Unknown status | Phase 4 | HMG-CoA Reductase add-on in Chronic Kidney Disease Patients With Proteinuria | June 5, 2018 | December 2021 |
| NCT03933046 | Unknown status | N/A | The Association Between Sleep Duration and Sleep Disorders and Proteinuria in Children | May 1, 2019 | September 1, 2021 |
| NCT02063100 | Unknown status | Phase 4 | Efficacy and Safety of Shenyankangfu Tablets for Primary Glomerulonephritis | February 2014 | |
| NCT00565396 | Unknown status | N/A | Effectiveness Study on Fosinopril and/or Losartan in Patients With Chronic Kidney Disease Stage 3 | September 2004 | July 2008 |
| NCT02173106 | Unknown status | Phase 2 | A Controlled Study of Steroids Plus Cyclosporin Therapy for Patients of Idiopathic Membranous Nephropathy | June 2014 | December 2016 |
| NCT02192801 | Unknown status | Kidney Function in Patients With Bladder Exstrophy | April 2014 | ||
| NCT02256995 | Unknown status | uChek Pilot Study for Urinalysis in the Antenatal Care Setting | November 2014 | June 2015 | |
| NCT00817037 | Unknown status | Phase 2 | Sitaxsentan in Proteinuric Chronic Kidney Disease | May 2007 | |
| NCT00858299 | Unknown status | Phase 4 | The Change of Urinary Angiotensinogen Excretion After Valsartan Treatment in Patients With Persistent Proteinuria | March 2009 | December 2011 |
| NCT02522650 | Unknown status | Phase 4 | A Crossover Pilot Study of the Effect of Amiloride on Proteinuria | July 2013 | October 2021 |
| NCT04939116 | Unknown status | Phase 2 | Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease | December 24, 2021 | August 31, 2023 |
| NCT01091324 | Unknown status | Phase 3 | Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) Patients | January 2010 | July 2010 |
| NCT01152060 | Unknown status | Treatment for HBV-MN Patients in Chinese: An Open Parallel Controlled Trial | January 2010 | November 2010 | |
| NCT02972346 | Unknown status | N/A | Availability Study of ACTH to Treat Children SRNS/SDNS | November 2016 | June 2019 |
| NCT02973178 | Unknown status | N/A | Scanadu Urine Device Validation Study Protocol | August 2016 | December 2016 |
| NCT01512862 | Unknown status | Phase 4 | Anti-proteinuric Effect of Calcitriol in Non-diabetic Kidney Disease Patients | January 2012 | December 2013 |
| NCT00508898 | Withdrawn | Phase 4 | The Efficacy and Safety of Calcitriol for the Treatment of Lupus Nephritis and Persistent Proteinuria | May 2008 | September 2009 |
| NCT01169857 | Withdrawn | Phase 4 | Velcade for Proliferative Lupus Nephritis | August 2010 | December 2012 |
| NCT00392132 | Withdrawn | Impact of Screening Patients With HIV for Kidney Disease | October 2005 | October 2006 | |
| NCT02382523 | Withdrawn | Phase 4 | Acthar on Proteinuria in IgA Nephropathy Patients | February 2015 | January 2020 |
| NCT00194974 | Withdrawn | Phase 1/Phase 2 | Treatment Targets for Chronic Hypertension in Pregnancy | July 2004 | March 2005 |
| NCT04531397 | Withdrawn | Phase 4 | Efficacy and Safety of Dapagliflozin in Children With Proteinuric Chronic Kidney Disease | January 1, 2021 | December 31, 2022 |
| NCT02882373 | Withdrawn | Phase 2 | Arginine in Treating Patients With Anti-VEGF Induced Kidney Injury | October 23, 2018 | May 15, 2019 |
| NCT00541619 | Withdrawn | Sympathetic Overactivity in Essential Hypertension | October 2007 | March 2011 |
- Disase is a (Disease Ontology)
- DOID:557
- Cross Reference ID (Disease Ontology)
- ICD10CM:R80
- Cross Reference ID (Disease Ontology)
- ICD9CM:791.0
- Cross Reference ID (Disease Ontology)
- MESH:D011507
- Cross Reference ID (Disease Ontology)
- NCI:C38012
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:144515004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0033687
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000093
- MeSH unique ID (MeSH (Medical Subject Headings))
- D011507