cleft lip

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Information
Disease name
cleft lip
Disease ID
DOID:9296
Description
"An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences." [url:https\://en.wikipedia.org/wiki/Cleft_lip_and_cleft_palate, url:https\://www.cdc.gov/ncbddd/birthdefects/cleftlip.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00004639 Completed Phase 2 Cleft Palate Surgery and Speech Development February 1996 April 2007
NCT00070811 Completed Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate August 2001 December 2012
NCT00097149 Completed N/A Systematic Pediatric Care for Oral Clefts - South America May 2003 May 2006
NCT00098319 Completed Phase 3 Oral Cleft Prevention Trial in Brazil January 2004 April 2007
NCT00397917 Completed Phase 3 Oral Cleft Prevention Program November 2006 July 2013
NCT00829101 Completed Articulation and Phonology in Children With Unilateral Cleft Lip and Palate January 2009 July 2014
NCT01252264 Completed FaceBase Biorepository November 2010 July 2015
NCT01380171 Completed Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes February 2007 December 2009
NCT02247193 Completed Phase 1/Phase 2 Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair December 2015 January 13, 2020
NCT02329509 Completed N/A Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients January 2010 September 2016
NCT02415361 Completed N/A Follow Ups of Parents With Infants With Cleft Lip and Palate April 2015 January 2019
NCT03314090 Completed Phase 3 Silicone Gel in the Treatment of Cleft Lip Scars January 28, 2014 October 12, 2017
NCT03480607 Completed Phase 4 Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair August 1, 2017 May 10, 2018
NCT04277273 Completed N/A Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris November 13, 2020 May 7, 2021
NCT04725370 Completed Characterization of Cleft Lip and Palate Conditions in Guatemala October 30, 2017 March 13, 2020
NCT05559281 Completed N/A Botulinum Toxin Injection in Reducing Lip Scar Following Cleft Lip Repair July 1, 2021 October 1, 2022
NCT05748340 Completed N/A Unilateral Cleft Lip Repair : Modified Millard and Mishra Technique April 1, 2021 September 1, 2022
NCT00340977 Completed Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment) September 6, 1995 November 18, 2019
NCT02702869 Enrolling by invitation Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) October 2016 December 2031
NCT04627389 Enrolling by invitation N/A Orbicularis Oris Z-plasty Modification of Modified Millard Technique and the Esthetic Outcome of Cleft Lip Repair October 1, 2020 June 1, 2023
NCT05357092 Not yet recruiting N/A Effects of AlignBabyCleft (ABaCleft) November 2022 November 2025
NCT06411444 Not yet recruiting N/A Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance May 15, 2024 April 15, 2025
NCT03537976 Recruiting N/A Targeting Surgeons' Decision-Making for Cleft Lip Surgery January 31, 2018 August 31, 2025
NCT01601171 Recruiting Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate March 2012 March 2030
NCT00213889 Terminated N/A TWIST Human Gene and Cleft Lips and Palates February 2003 July 2008
NCT00975208 Unknown status Osteogenesis and Dental Eruption Through Electrical Stimuli January 2006 August 2010
NCT03839290 Unknown status Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty September 2016 May 2019
NCT00285714 Unknown status N/A 3D Imaging of Hard and Soft Tissue in Orthognathic Surgery February 2006 December 2010
NCT02454998 Unknown status N/A Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment February 2011 August 2015
NCT03572907 Withdrawn Use of Titanium Plate in Rhinoplasty in Patients With Cleft Lip and Palate : Aesthetic and Functional Impact. October 2018 February 2019
NCT04334590 Withdrawn Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities June 8, 2020 April 2022
Disase is a (Disease Ontology)
DOID:0050567
Cross Reference ID (Disease Ontology)
EFO:0003959
Cross Reference ID (Disease Ontology)
ICD10CM:Q36
Cross Reference ID (Disease Ontology)
ICD9CM:749.1
Cross Reference ID (Disease Ontology)
ICD9CM:749.11
Cross Reference ID (Disease Ontology)
MESH:D002971
Cross Reference ID (Disease Ontology)
NCI:C87175
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:156941008
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:62696001
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0008924
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0158651
Exact Synonym (Disease Ontology)
cheiloschisis
Exact Synonym (Disease Ontology)
cleft lip, unilateral, complete
Exact Synonym (Disease Ontology)
complete unilateral cleft lip
Exact Synonym (Disease Ontology)
hare lip
Exact Synonym (Disease Ontology)
Labium leporinum
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0410030
ICD10 preferred id (Insert disease from ICD10)
D0013767
ICD10 class code (Insert disease from ICD10)
Q36
MeSH unique ID (MeSH (Medical Subject Headings))
D002971