Hypercapnia

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Information
Disease name
Hypercapnia
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00001845 Completed Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide) September 1999 August 2004
NCT00006318 Completed Role of Prostaglandins in the Regulation of Brain Blood Flow September 2000 December 2003
NCT00173017 Completed N/A The Physiological Impact of N95 Masks on Medical Staff August 2003 June 2005
NCT00619606 Completed Phase 2 To Determine the Efficacy of the TwinGuard in Oxygen Delivery During and Post Endoscopic Procedure November 2006 March 2007
NCT00708526 Completed N/A Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea March 2008 November 2008
NCT01815034 Completed Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations March 2013 July 2013
NCT01826968 Completed Phase 2 Alveolar Recruitment Maneuver During Cesarean Section Improves Lung Compliance January 2013 March 2014
NCT01873612 Completed Phase 4 Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers May 2013 September 2014
NCT01882257 Completed N/A Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury October 2011 February 2016
NCT01898858 Completed Effects of O2 and/or CO2 Inhalation on Rest and Exercise Pulmonary Hemodynamic September 2013 October 2014
NCT02068274 Completed CO2 Monitoring Study September 2013 August 2017
NCT02429154 Completed N/A Assessment of Cerebral Vasoreactivity Using Near-infrared Spectroscopy (NIRS) in Infants (VARO) September 2015 September 30, 2017
NCT02504814 Completed N/A Physiological and Clinical Changes in NHF Therapy June 2011 June 2018
NCT02757573 Completed N/A The Right Ventricular Responses to Mild Hypercarbia After Mitral Valve Repair Surgery April 2016 December 2019
NCT02877290 Completed N/A The Effect of Non-invasive Ventilation on the Oxygenation of Peripheral Muscle in Hypercapnic COPD Patients August 2016 October 2017
NCT02917668 Completed N/A Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Cardiac Surgery Patients September 2016 January 8, 2018
NCT03221387 Completed N/A Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients September 10, 2017 December 15, 2019
NCT03303807 Completed N/A Correction by ECCO2-R of Hypercapnia in Patients With DVP in Moderate to Severe ARDS Under Protective Ventilation. January 10, 2018 March 21, 2019
NCT03797300 Completed N/A Pulse Oximeter and Respiratory Rate Test December 12, 2018 December 14, 2018
NCT04041531 Completed N/A Triple H ODC Trial August 26, 2019 February 10, 2020
NCT04304339 Completed Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study December 14, 2021 July 13, 2022
NCT04310579 Completed Phase 1 Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation June 15, 2020 May 25, 2021
NCT04409470 Completed Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients October 11, 2021 March 27, 2022
NCT04497090 Completed N/A Adaptive Non-invasive Ventilation to Abolish Tidal Flow Limitation October 23, 2014 May 15, 2018
NCT04512781 Completed N/A Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs October 1, 2020 June 7, 2022
NCT04780724 Completed N/A Evaluation of SpO2 Measurement Using a Smartwatch February 15, 2021 March 30, 2021
NCT04793178 Completed N/A The Effectivity of End-tidal CO2 and Oxygen Reserve Index (ORI) Monitoring in Sedation December 25, 2015 March 1, 2017
NCT04980820 Completed N/A Changes in Capillary Carbon Dioxide Partial Pressure (pCO2) While Wearing FFP2 / FFP3 Masks July 19, 2021 February 28, 2022
NCT05116397 Completed N/A Influence of Graded Hypercapnia on Endurance Exercise Performance September 10, 2021 April 14, 2022
NCT05189158 Completed N/A Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants October 15, 2021 October 15, 2021
NCT05470465 Completed Phase 1 Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation September 1, 2022 September 17, 2023
NCT05793437 Completed N/A Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light April 1, 2023 January 28, 2024
NCT05948527 Completed N/A Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia January 1, 2023 July 1, 2023
NCT05972304 Completed N/A Efficiency and Safety of Nasal Positive Airway Pressure Systems During Endoscopy April 1, 2022 December 1, 2022
NCT06132490 Completed N/A Intra-abdominal Pressure and Insufflator Effects in Robotic Surgery July 15, 2022 December 30, 2023
NCT00888342 Completed N/A Changes in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in COPD Patients May 2009 July 2011
NCT00962078 Completed N/A Pulmonary Rehabilitation in Patients Before Lung Transplantation (LTx) July 2008 October 2010
NCT01157624 Completed Phase 1 Application of Nasal Cannula With Oxygen Versus Air During Eye Surgery Under Local Anaesthetic May 2010 December 2010
NCT01317329 Completed N/A "Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved" March 2011 December 2014
NCT01499550 Completed N/A Nocturnal Transnasal Insufflation (nTNI) August 2011 July 2012
NCT01575327 Completed N/A Closed-loop System for Oxygen Delivery and Exercise in Chronic Obstructive Pulmonary Disease July 2012 June 2016
NCT01782625 Completed N/A Hypercapnia: Cognitive Effects and Monitoring January 2013 February 2016
NCT01784367 Completed N/A Extracorporeal Lung Assist to Avoid Intubation in Patients Failing NIV for Hypercapnic ARF December 2012 April 2015
NCT04771663 Enrolling by invitation N/A Variability of SpO2 Measurements Depending on the Choice of Finger for Sensor Placement January 10, 2021 October 15, 2023
NCT04258774 Enrolling by invitation N/A The Effect of Respiratory Challenge on the BOLD Signal January 29, 2020 December 31, 2027
NCT05441007 Enrolling by invitation N/A The Effect of Hypercapnia on Physiological Parameters During Short-term Breathing June 26, 2022 June 30, 2024
NCT06298435 Not yet recruiting Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements March 1, 2024 April 1, 2025
NCT06212180 Not yet recruiting Comfort of Patients Under Non Invasive Ventilation According to the Mask January 2024 December 2024
NCT06303518 Not yet recruiting N/A End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children May 2024 December 31, 2024
NCT05761756 Recruiting N/A Oxygen Toxicity: Mechanisms in Humans November 28, 2023 March 2026
NCT06158295 Recruiting Phase 3 Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function December 1, 2023 May 1, 2025
NCT04871893 Recruiting N/A Safety and Efficacy Evaluation of CO2 Removal in Combination With Continuous Veno-Venous Hemodialysis/Hemodiafiltration Therapy March 25, 2022 December 2024
NCT05829083 Recruiting N/A DUET Versus Standard Interface for Hypercapnic COPD Patients July 18, 2023 May 1, 2024
NCT06158256 Recruiting Phase 3 Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function December 1, 2023 May 1, 2025
NCT06158282 Recruiting Phase 3 Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function December 1, 2023 May 1, 2025
NCT06150677 Recruiting Phase 3 Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function December 1, 2023 May 1, 2025
NCT05505279 Recruiting Phase 3 Ventilatory Effects of THRIVE During EBUS October 5, 2022 April 2024
NCT05536076 Recruiting N/A Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury March 1, 2023 February 28, 2025
NCT04590014 Terminated N/A Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Device Equivalence January 12, 2022 July 15, 2022
NCT03522805 Terminated N/A Impact of Non-invasive Ventilation in Hypercapnic COPD April 23, 2018 November 21, 2018
NCT03934749 Terminated Non-invasive Home Ventilation in Patients With Severe Hypercapnic Chronic Obstructive Pulmonary Disease June 27, 2019 September 27, 2020
NCT00710541 Terminated N/A Non-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD) October 2004 December 2012
NCT04926805 Terminated N/A Physiological Study to Compare Noninvasive Ventilation (NIV) Masks July 7, 2021 July 5, 2023
NCT02801162 Terminated N/A Evaluation of Accuracy and Precision of a New Arterial Blood Gas Analysis System Blood in Comparison With the Reference Standard September 2016 April 2017
NCT01997528 Unknown status N/A Gas Transfer on ILA-Activve November 2013
NCT05188651 Unknown status Effect of FFP2 Masks on Peripheral Oxygen Saturation and Pulse Rate During the COVID-19 Pandemic January 2022 April 2022
NCT03741998 Unknown status N/A Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange November 7, 2018 December 30, 2019
NCT01774422 Unknown status Phase 2 Use of the Medical Device DECAP CO2 for the Treatment of Hypercapnic Respiratory Distress in Patients Under Noninvasive Ventilation January 2013 January 2015
NCT01693146 Unknown status Phase 1 STIT-2: Evaluation of Safety and Efficacy of Short-time TNI® Treatment in Patients With COPD and Hypercapnia December 2011 December 2013
NCT02980770 Unknown status Postoperative Complications in Patients With Obesity Hypoventilation Syndrome November 2016 June 2018
NCT01835600 Unknown status N/A Suspension of Mechanical Ventilation in Ureteroscopic Lithotripsy Under General Anesthesia April 2013 November 2013
NCT02201875 Unknown status Intrinsic Periodic Pattern of Breathing September 2014 December 2015
NCT03066115 Withdrawn Phase 1 Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation December 1, 2020 December 1, 2021
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0012416
MeSH unique ID (MeSH (Medical Subject Headings))
D006935