thrombocytopenia
Information
- Disease name
- thrombocytopenia
- Disease ID
- DOID:1588
- Description
- "A blood platelet disease that is characterized by low a platelet count in the blood." [url:http\://en.wikipedia.org/wiki/Thrombocytopenia, url:http\://ghr.nlm.nih.gov/glossary=thrombocytopenia, url:http\://www.merckmanuals.com/professional/hematology_and_oncology/thrombocytopenia_and_platelet_dysfunction/overview_of_platelet_disorders.html]
Disease area statistics
Chromosome band
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04478227 | Active, not recruiting | Early Phase 1 | TPO-Mimetic Use in Children for Hematopoietic Failure | August 18, 2020 | June 2024 |
| NCT02912208 | Active, not recruiting | Phase 2 | Eltrombopag for the Treatment of Thrombocytopenia Due to Low- and Intermediate Risk Myelodysplastic Syndromes | June 11, 2011 | October 2026 |
| NCT04673266 | Active, not recruiting | Phase 2 | Using Romiplostim to Treat Low Platelet Counts During Chemotherapy in People With Lymphoma | December 14, 2020 | December 2025 |
| NCT04014166 | Active, not recruiting | N/A | Study of Human Umbilical Cord-derived Mesenchymal Stem Cells for Treatment of Refractory Immune Thrombocytopenia | November 21, 2019 | June 30, 2023 |
| NCT03059030 | Active, not recruiting | N/A | Yttrium-90 Radioembolization for Cirrhosis-Associated Thrombocytopenia | March 16, 2017 | April 1, 2025 |
| NCT05396157 | Active, not recruiting | Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study | November 1, 2021 | December 1, 2024 | |
| NCT04837703 | Available | MAP to Provide Access to Eltrombopag, for Treatment of Patients With Medically Significant Thrombocytopenia | |||
| NCT00015639 | Completed | Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH Campus | April 2001 | February 2004 | |
| NCT00031980 | Completed | Phase 2 | Cyclosporine in Treating Patients With Low Blood Counts Caused By Hematologic Cancer | March 2002 | May 2005 |
| NCT00037791 | Completed | Phase 3 | Safety and Efficacy of (PN-152,243)/PN-196,444 in the Prevention of Thrombocytopenia | December 1999 | September 2002 |
| NCT00039858 | Completed | Phase 4 | Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin | September 2003 | March 2006 |
| NCT00039910 | Completed | Phase 3 | Safety and Efficacy of (PN-152,243)/PN-196,444 in the Prevention of Thrombocytopenia | July 2000 | March 2003 |
| NCT00049725 | Completed | Phase 2 | Daclizumab to Treat Chronic Immune Thrombocytopenia | November 2002 | December 2004 |
| NCT00073580 | Completed | Phase 3 | Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE) | October 2003 | |
| NCT00001533 | Completed | Phase 1 | Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine | September 1996 | September 2000 |
| NCT00102323 | Completed | Phase 3 | AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Refractory to Splenectomy | March 29, 2005 | March 1, 2007 |
| NCT00102336 | Completed | Phase 3 | AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Prior to Splenectomy | April 7, 2005 | April 1, 2007 |
| NCT00110799 | Completed | Phase 2 | SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C | April 2005 | November 2006 |
| NCT00116688 | Completed | Phase 3 | Open Label Extension Study of Romiplostim (AMG 531) in Thrombocytopenic Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | August 2004 | January 2010 |
| NCT00118664 | Completed | Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children | May 2005 | February 2012 | |
| NCT00128713 | Completed | Phase 3 | Optimal Platelet Dose Strategy for Management of Thrombocytopenia | July 2004 | January 2008 |
| NCT00151866 | Completed | Phase 3 | Efficacy of Transfusions With Platelets Stored in Platelet Additive Solution II Versus Plasma | October 2003 | May 2005 |
| NCT00260689 | Completed | Phase 2 | Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia | November 28, 2005 | May 4, 2016 |
| NCT00261924 | Completed | Phase 3 | Efficacy and Safety Study of Platelets Treated for Pathogen Inactivation and Stored for Up to Seven Days | October 2005 | July 2009 |
| NCT00263809 | Completed | Early Phase 1 | Safety and Performance of MIRASOL® PRT Treated Platelet Transfusion Products | December 2005 | October 2007 |
| NCT00283439 | Completed | Phase 1/Phase 2 | A Dose and Schedule Finding Trial With AMG 531 for Chemotherapy Induced Thrombocytopenia (CIT) in Adults With Lymphoma | October 2005 | September 2008 |
| NCT00303472 | Completed | Phase 2 | Determination of Safe Dose of Romiplostim (AMG 531) in Patients With Myelodysplastic Syndromes (MDS) | February 2006 | May 2008 |
| NCT00305708 | Completed | Phase 1/Phase 2 | Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission | August 2000 | July 2004 |
| NCT00321711 | Completed | Phase 2 | Determination of Safe and Effective Dose of Romiplostim (AMG 531) in Subjects With Myelodysplastic Syndrome (MDS)Receiving Hypomethylating Agents | October 1, 2006 | October 19, 2009 |
| NCT00333333 | Completed | Mechanism of Thrombocytopenia in Infants | June 2006 | June 2008 | |
| NCT00413283 | Completed | Phase 2 | Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC) | December 2006 | February 2009 |
| NCT00415532 | Completed | Phase 3 | Romiplostim (AMG 531) Versus Medical Standard of Care for Immune (Idiopathic) Thrombocytopenic Purpura | December 1, 2006 | May 11, 2009 |
| NCT00418665 | Completed | Phase 2 | A Safety and Efficacy Study to Evaluate AMG 531 Treatment in Subject With Myelodysplastic Syndrome Receiving Revlimid | December 2006 | October 2010 |
| NCT00454857 | Completed | Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | May 2006 | August 2008 | |
| NCT00472290 | Completed | N/A | Evaluating the Safety of Long Term Dosing of Romiplostim (Formerly AMG 531) in Thrombocytopenic Subjects With Myelodysplastic Syndromes (MDS) | April 1, 2007 | December 26, 2011 |
| NCT00508820 | Completed | Phase 3 | An Open Label Study of Romiplostim in Adult Thrombocytopenic Subjects With ITP | February 1, 2005 | March 1, 2011 |
| NCT00549484 | Completed | Thrombopoietin Levels and Platelet Transfusion in Neonates | May 2003 | September 2004 | |
| NCT00608738 | Completed | N/A | Using Whole-Person-Care Guide in Patients Receiving Care for Cancer or Complications From Cancer Treatment | July 2001 | January 2005 |
| NCT00614523 | Completed | Phase 2 | Romiplostim Treatment of Thrombocytopenia in Subjects With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) | July 21, 2008 | November 30, 2015 |
| NCT00730314 | Completed | Phase 1/Phase 2 | Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells | August 2008 | August 2015 |
| NCT00735930 | Completed | Phase 1 | Lenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | August 2008 | November 2014 |
| NCT00748878 | Completed | Platelet Function During ECMO (Extra Corporeal Membrane Oxygenation) | June 2008 | June 2013 | |
| NCT00759980 | Completed | Transfusing Neonates Based on Platelet Mass | October 2008 | March 2011 | |
| NCT00771810 | Completed | Phase 2 | Study of Drug to Reduce Thrombocytopenia in Patients Receiving Chemo for Ovarian, Fallopian Tube or Peritoneal Cancer | October 2008 | December 2011 |
| NCT00787241 | Completed | Platelet Count Trends in Pre-eclamptic Parturients | September 2002 | May 2003 | |
| NCT00903929 | Completed | Phase 1 | Phase I Study of Eltrombopag for Promoting Thrombopoiesis After Total Body Irradiation | December 2009 | December 2015 |
| NCT00907478 | Completed | Phase 4 | Study on Bone Marrow Morphology in Adults Receiving Romiplostim for Treatment of Thrombocytopenia Associated With Immune Thrombocytopenia Purpura (ITP) | August 11, 2009 | January 14, 2014 |
| NCT02389621 | Completed | Phase 3 | Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures | June 15, 2015 | April 19, 2017 |
| NCT00002665 | Completed | Phase 2 | SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia | July 1995 | December 2003 |
| NCT00003619 | Completed | Phase 1/Phase 2 | Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia | February 1998 | April 2004 |
| NCT00004215 | Completed | Phase 2 | Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia | August 1999 | August 2000 |
| NCT00004378 | Completed | N/A | Stem Cell Transplantation (SCT) for Genetic Diseases | January 1995 | |
| NCT00004787 | Completed | Phase 2 | Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes | December 1994 | |
| NCT00012376 | Completed | Phase 1 | Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer | March 2001 | |
| NCT02530515 | Completed | Phase 2 | Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia | December 18, 2015 | April 30, 2018 |
| NCT02578901 | Completed | Phase 3 | American Trial Using Tranexamic Acid in Thrombocytopenia | June 2016 | June 11, 2020 |
| NCT02679443 | Completed | N/A | Vitamin Supplementation in NSCLC Patients on Pemetrexed Based Chemotherapy | July 2015 | December 2016 |
| NCT00001630 | Completed | Phase 1 | Treatment of Autoimmune Thrombocytopenia (AITP) | July 21, 1997 | June 11, 2009 |
| NCT02718716 | Completed | Phase 2 | Study to Evaluate Safety, Tolerability and Efficacy of UCB7665 in Subjects With Primary Immune Thrombocytopenia | March 2, 2016 | February 4, 2019 |
| NCT02780414 | Completed | Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers | January 2016 | October 23, 2020 | |
| NCT02783313 | Completed | N/A | Pathogen Reduction Evaluation & Predictive Analytical Rating Score | November 17, 2010 | June 30, 2016 |
| NCT03355742 | Completed | N/A | XIENCE 28 Global Study | February 9, 2018 | April 30, 2020 |
| NCT02845609 | Completed | Phase 2 | Efficacy of Sialic Acid GNE Related Thrombocytopenia | September 2016 | September 2017 |
| NCT02858323 | Completed | Complement (C1q) Binding to HLA Antibodies in a Solid-phase Immunoassay and Clinical Effect on Platelet Transfusion | July 27, 2016 | June 20, 2017 | |
| NCT02862353 | Completed | Thrombocytopenia Drug Immune Validation of New Biological Test Diagnostic | October 25, 2017 | March 15, 2021 | |
| NCT00922883 | Completed | Phase 2 | A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients | May 29, 2009 | April 24, 2018 |
| NCT00948792 | Completed | N/A | Study of the Effect of Differing Platelet Transfusion Times in Neonates | May 2009 | December 2010 |
| NCT00961064 | Completed | Phase 2 | A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS) | March 15, 2011 | December 30, 2021 |
| NCT01000051 | Completed | Phase 2 | Eltrombopag for Post Transplant Thrombocytopenia | February 17, 2010 | April 4, 2018 |
| NCT01002755 | Completed | Phase 2 | Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | January 19, 2010 | January 31, 2018 |
| NCT05585463 | Completed | Safety of Acupuncture and Intracutaneous Needles in Pediatric Cancer Patients: a Retrospective Study (ACUSAFE2021) | September 1, 2019 | October 31, 2021 | |
| NCT01163110 | Completed | Phase 1 | Study to Investigate the Therapeutic Role of RNA Fragments in Platelet Production During Chemotherapy | March 2004 | June 2007 |
| NCT01165996 | Completed | Phase 1/Phase 2 | Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome | July 2010 | August 2012 |
| NCT05439265 | Completed | EMR Tool Impact on HIT Documentation and Management | January 2014 | April 2017 | |
| NCT01355289 | Completed | Phase 2 | Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501 | November 2011 | May 2014 |
| NCT01356576 | Completed | Effect of Hemodialysis Membranes on Platelet Count | September 2010 | September 2011 | |
| NCT04917679 | Completed | Phase 2 | Eltrombopag Plus Diacerein vs Eltrombopag in Adult ITP | September 1, 2020 | June 1, 2022 |
| NCT01428635 | Completed | Phase 2/Phase 3 | Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy | January 13, 2012 | January 3, 2022 |
| NCT01444417 | Completed | Phase 3 | Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients | January 2012 | February 2015 |
| NCT01481220 | Completed | Phase 1 | Safety Study of Eltrombopag Combined With Azacitidine to Treat Myelodysplastic Syndrome (MDS) | October 2011 | May 2013 |
| NCT04609891 | Completed | N/A | Avatrombopag on the Treatment of Thrombocytopenia Induced by Chemotherapy of Malignant Tumors | May 26, 2020 | May 16, 2021 |
| NCT01791101 | Completed | Phase 2 | Eltrombopag in Patients With Delayed Post Transplant Thrombocytopenia. | September 16, 2013 | June 26, 2020 |
| NCT04348799 | Completed | Thrombocytopoiesis and Platelet Homeostasis in Infants With Bronchoplumonary Dysplasia | January 1, 2019 | January 1, 2020 | |
| NCT01965626 | Completed | Phase 2 | A Multicenter Randomized Open-label Study of Oseltamivir Combined With HD-DEX Versus HD-DEX in the Management of ITP | February 1, 2016 | May 2019 |
| NCT04155775 | Completed | N/A | Effects of a Platelet Transfusion Best Practices Alert | May 9, 2019 | February 4, 2020 |
| NCT01974401 | Completed | Phase 2 | Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood Dyscrasia | January 2010 | June 2012 |
| NCT03835598 | Completed | Post-Operative Thrombocytopenia After Bio-prosthesis Implantation | June 28, 2019 | May 31, 2021 | |
| NCT02039076 | Completed | Phase 1 | A Five-Treatment-Period Study to Evaluate the Single-Dose Pharmacokinetics and Pharmacodynamics of Avatrombopag in Healthy Japanese and White Subjects | December 2013 | September 2014 |
| NCT02068755 | Completed | Blood Products in Cardiac Surgery | January 2002 | December 2012 | |
| NCT03815175 | Completed | N/A | XIENCE 28 USA Study | February 25, 2019 | February 4, 2021 |
| NCT02078284 | Completed | Phase 1 | Phase 1 Safety Study of Dimethyl Sulfoxide Cryopreserved Platelets | November 5, 2014 | July 17, 2016 |
| NCT03754634 | Completed | Phase 2 | A Prospective, Open, Multicenter Clinical Trial of Eltrombopag Combined With Diacerein in Eltrombopag-inefficient or Relapsed ITP | May 1, 2019 | November 1, 2020 |
| NCT03716310 | Completed | Platelet Reactivity in Septic Shock | April 1, 2017 | August 30, 2018 | |
| NCT03636698 | Completed | Effect of Chorioamnionitis on Platelet Activation and Placental Vessel Among Preterm Infants by Wnt-Flt1 Signal Pathway | June 1, 2016 | December 31, 2016 | |
| NCT03567798 | Completed | N/A | Thrombocytopenia Induced by Chemotherapy | July 18, 2017 | November 20, 2017 |
| NCT02263157 | Completed | Evaluate the Association Between Infection and Thrombocytopenia | January 2013 | June 2014 | |
| NCT02267993 | Completed | Phase 4 | Efficacy and Safety of rhTPO for the Treatment of Thrombocytopenia After Chemotherapy in AML Patients | October 2014 | August 31, 2018 |
| NCT03515447 | Completed | Romiplostim in Thoracic Transplantation | May 1, 2014 | October 31, 2015 | |
| NCT02298933 | Completed | Phase 2 | Complement Inhibition Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients With Severe Thrombocytopenia | November 21, 2014 | August 8, 2017 |
| NCT02306044 | Completed | Bleeding Prediction in Thrombocytopenia | April 2013 | December 2013 | |
| NCT02323178 | Completed | Phase 1/Phase 2 | A Study of Eltrombopag in Patients With CMML and Thrombocytopenia | August 7, 2014 | April 2021 |
| NCT03515096 | Completed | Phase 3 | Eltrombopag vs. rhTPO to Increase Platelet Level After HSCT | July 1, 2018 | July 1, 2022 |
| NCT02371330 | Completed | The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia Study | April 2015 | September 2017 | |
| NCT02948283 | Completed | Phase 1 | Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia | September 5, 2017 | December 1, 2017 |
| NCT03394755 | Completed | Phase 1 | Thrombosomes® in Bleeding Thrombocytopenic Patients | March 19, 2018 | September 25, 2019 |
| NCT02487563 | Completed | Phase 3 | Prospective Study of Patients With Thrombocytopenia Following HSCT | October 2015 | April 12, 2019 |
| NCT04272970 | Enrolling by invitation | N/A | Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) | July 7, 2020 | December 2024 |
| NCT05038722 | Enrolling by invitation | Function of Platelets Used for Transfusions | November 22, 2018 | December 31, 2026 | |
| NCT05998759 | Not yet recruiting | Phase 2 | Telitacicept for the Treatment of Connective Tissue Disease-associated Thrombocytopenia | October 2023 | December 2025 |
| NCT06036966 | Not yet recruiting | Phase 2 | The Efficacy and Safety of Hetrombopag in Primary Prevention of Thrombocytopenia Induced by the Niraparib Maintenance in Advanced Ovarian Cancer Patients | September 16, 2023 | July 15, 2025 |
| NCT06095648 | Not yet recruiting | N/A | Study Comparing Platelet Transfusion Volumes in Premature Babies | October 28, 2023 | August 2028 |
| NCT05672420 | Not yet recruiting | Phase 1/Phase 2 | Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies | January 1, 2023 | January 31, 2025 |
| NCT06202625 | Not yet recruiting | Phase 2/Phase 3 | Efficacy and Safety of Avatrombopag in the Treatment of Thrombocytopenia After Haplo-HSCT | January 15, 2024 | October 30, 2025 |
| NCT06349577 | Not yet recruiting | N/A | Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury | April 2024 | October 2028 |
| NCT05958511 | Not yet recruiting | Assessment of Risk Factors and Outcome of Thrombocytopenia in ICU Patients | September 1, 2023 | December 1, 2024 | |
| NCT06245746 | Not yet recruiting | Phase 1 | UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid Leukemia | March 2024 | December 2025 |
| NCT05411874 | Not yet recruiting | Phase 2 | A Multicenter Randomized Open-label Study of Chidamide Plus HD-DEX Versus HD-DEX in ITP | October 1, 2022 | October 30, 2024 |
| NCT06433830 | Recruiting | Phase 2 | Hetrombopag for the Thrombocytopenia Induced by Concurrent Chemoradiotherapy | May 10, 2022 | July 30, 2025 |
| NCT02707497 | Recruiting | Phase 2/Phase 3 | The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia | April 1, 2019 | September 30, 2024 |
| NCT03638817 | Recruiting | Phase 2 | Perioperative Eltrombopag in Patients With Inherited Thrombocytopenia | August 2, 2019 | December 2023 |
| NCT03712618 | Recruiting | Phase 2 | The SOLID Platelet Study | June 10, 2019 | December 31, 2026 |
| NCT04003220 | Recruiting | Idiopathic Chronic Thrombocytopenia of Undetermined Significance : Pathogenesis and Biomarker | September 7, 2020 | September 7, 2023 | |
| NCT04800458 | Recruiting | N/A | Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis | May 19, 2021 | May 2027 |
| NCT04889326 | Recruiting | Collection of the Thrombo-VaxCov Cohort | April 2, 2021 | May 2023 | |
| NCT04931849 | Recruiting | Early Phase 1 | Study of Avatrombopag for Temozolomide-induced Thrombocytopenia in Glioma (APATIT-G) | May 6, 2022 | September 30, 2024 |
| NCT05053100 | Recruiting | Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study | August 17, 2021 | August 18, 2025 | |
| NCT05199909 | Recruiting | Phase 2 | Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia | January 25, 2022 | June 30, 2024 |
| NCT05255003 | Recruiting | Phase 4 | STrategies for Anticoagulation in Patients With thRombocytopenia and Cancer-associated Thrombosis | August 29, 2022 | March 31, 2025 |
| NCT05382013 | Recruiting | Phase 4 | Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment | April 27, 2022 | April 30, 2024 |
| NCT05410249 | Recruiting | Assessment of FOXP3 Gene Polymorphisms and Serum Interleukin 10 in Patients With ITP | June 10, 2022 | September 30, 2023 | |
| NCT05563064 | Recruiting | Phase 3 | Effect of Herbal Formulation on Thrombocytes Count | January 1, 2021 | January 1, 2023 |
| NCT05634005 | Recruiting | N/A | Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence | February 1, 2023 | December 2024 |
| NCT05711485 | Recruiting | N/A | Platelet-Directed Whole Blood Transfusion Strategy for Malaria | February 24, 2024 | February 28, 2025 |
| NCT05944809 | Recruiting | Phase 2 | The Effect of Prophylactic TPO Combined With BMS-IMRT to Esophageal Cancer Patients | July 20, 2023 | December 31, 2024 |
| NCT05983952 | Recruiting | Phase 2 | Anti-CD38 Antibody Treating APS With Thrombocytopenia | August 2023 | August 2025 |
| NCT06001567 | Recruiting | Phase 2 | Avatrombopag for HCC Patients With Thrombocytopenia Who Intend to Undergo TACE and/or HAIC | August 14, 2023 | August 13, 2024 |
| NCT06053021 | Recruiting | N/A | Antiplatelet Therapy for AIS Patients With Thrombocytopenia | September 15, 2023 | January 1, 2026 |
| NCT06087198 | Recruiting | Clinical Performance Evaluation of T-TAS®01 HD Chip | September 25, 2023 | March 31, 2024 | |
| NCT06187831 | Recruiting | Bleeding Events Before vs After Lowering Departmental Platelet Transfusion Trigger | February 26, 2024 | April 20, 2025 | |
| NCT06291415 | Recruiting | Phase 1 | The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) | April 2, 2024 | November 2026 |
| NCT02227576 | Terminated | Phase 2 | Prevention of Thrombocytopenia in Glioblastoma Patients | July 10, 2014 | December 14, 2017 |
| NCT03806556 | Terminated | Phase 1/Phase 2 | A Pediatric Trial Using Tranexamic Acid in Thrombocytopenia | April 22, 2019 | August 25, 2020 |
| NCT02074436 | Terminated | Phase 2 | PRevention Of BLeeding in hEmatological Malignancies With Antifibrinolytic (Epsilon Aminocaproic Acid) | May 23, 2014 | May 14, 2021 |
| NCT02032134 | Terminated | Phase 4 | Protocol for the Infusion of Buffy Coat-derived Cryopreserved Platelets in Patients With Severe Thrombocytopenia | July 2015 | June 2016 |
| NCT01821625 | Terminated | Phase 2/Phase 3 | Study of Quadruple Therapy With Eltrombopag for Chronic Hepatitis C | April 2013 | April 2016 |
| NCT01727401 | Terminated | Phase 4 | Thromboprophylaxis of Venous Thromboembolism in Acutely-ill Medical Inpatients With Thrombocytopenia | November 2012 | July 2021 |
| NCT04543279 | Terminated | Phase 2 | Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia | May 3, 2021 | July 30, 2022 |
| NCT01676961 | Terminated | Phase 2 | Romiplostim in Increasing Low Platelet Counts in Patients With Multiple Myeloma Receiving Chemotherapy | January 2013 | November 2015 |
| NCT04631211 | Terminated | Phase 2 | Thrombosomes® in Bleeding Thrombocytopenic Patients Study | March 5, 2021 | January 7, 2022 |
| NCT00420914 | Terminated | Phase 3 | Strategies for Transfusion of Platelets (SToP) | October 2003 | |
| NCT01484314 | Terminated | Phase 2 | Eltrombopag for Thrombocytopenia in Patients With Relapsed Multiple Myeloma | April 2012 | September 2015 |
| NCT01153919 | Terminated | Phase 2 | Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia | June 30, 2010 | July 14, 2018 |
| NCT01397149 | Terminated | Phase 1/Phase 2 | Eltrombopag in Thrombocytopenic Chronic Lymphocytic Leukemia (CLL) Patients (CLL2S Study of GCLLSG) | October 2011 | November 2014 |
| NCT00074165 | Terminated | Phase 2 | Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen | January 2003 | December 2010 |
| NCT01368211 | Terminated | Phase 2/Phase 3 | Mirasol-Treated Platelets - (Pathogen Reduction Extended Storage Study) | September 2010 | May 2011 |
| NCT00501345 | Terminated | Phase 3 | Aspirin in Patients With Myocardial Infarction and Thrombocytopenia | February 2002 | February 2008 |
| NCT00909363 | Terminated | Phase 2 | Thrombocytopenia and Bleeding in Wiskott-Aldrich Syndrome (WAS) Patients | June 2009 | June 30, 2017 |
| NCT00239733 | Terminated | Phase 4 | Anti-D for Treating Thrombocytopenia in Adults Infected With Hepatitis C Virus With or Without HIV Co-Infection | March 2005 | February 2010 |
| NCT00678587 | Terminated | Phase 3 | Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures | June 2008 | October 2009 |
| NCT01286038 | Terminated | Phase 1 | Eltrombopag in Myelodysplastic Syndrome (MDS) Patients With Thrombocytopenia | April 6, 2011 | November 3, 2018 |
| NCT00471653 | Terminated | Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy | November 11, 2006 | August 18, 2009 | |
| NCT03195010 | Terminated | Phase 2 | Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia | June 9, 2017 | December 21, 2018 |
| NCT03303950 | Terminated | Phase 2 | Allogeneic Stem Cell Transplantation for Multiple Myeloma and Myelofibrosis | March 30, 2018 | February 19, 2020 |
| NCT03326843 | Terminated | Phase 3 | Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure | March 26, 2018 | February 25, 2019 |
| NCT03391856 | Terminated | Phase 2/Phase 3 | Prolonged Isolated Thrombocytopenia After Allo-SCT : N-acetyl-L-cysteine (NAC) Versus Supportive Therapy | March 1, 2018 | December 30, 2018 |
| NCT02444728 | Terminated | Phase 3 | Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLE | July 2015 | December 30, 2018 |
| NCT02276651 | Terminated | Observational Trial of a Therapeutic Platelet Transfusion Regimen | November 2014 | June 6, 2017 | |
| NCT03554759 | Terminated | Avatrombopag for the Treatment of Thrombocytopenia in Adults With Chronic Liver Disease Undergoing a Procedure | July 2, 2018 | January 31, 2019 | |
| NCT00594685 | Terminated | Evaluating the Presence of Blood Clots in People With Heparin-Induced Thrombocytopenia (HIT) (The HOT Study) | January 2008 | September 2008 | |
| NCT02241031 | Unknown status | Phase 2/Phase 3 | Megakaryocytic Progenitor Cells for Prophylaxis and Treatment of Thrombocytopenia | September 2014 | December 2016 |
| NCT05087459 | Unknown status | Treatment of Avatrombopag for Thrombocytopenia in Patients Undergoing Selective Resection of Hepatocellular Carcinoma | June 30, 2021 | July 2022 | |
| NCT05095844 | Unknown status | National Vaccine Adverse Event Reporting Survey and Etiology | March 15, 2022 | April 1, 2024 | |
| NCT05193201 | Unknown status | Phase 1 | A Phase Ib Clinical Study for rhTPO in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease | January 16, 2022 | December 31, 2022 |
| NCT03429660 | Unknown status | French Adult Primary Immune Thrombocytopenia | October 2013 | May 2023 | |
| NCT05217719 | Unknown status | Phase 4 | Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients | February 2022 | October 2023 |
| NCT05225493 | Unknown status | HIV Indicator Diseases in Hospital and Primary Care | January 1, 2020 | May 2024 | |
| NCT02094248 | Unknown status | Phase 2/Phase 3 | rhTPO in Critical Patients With Thrombocytopenia | March 2014 | April 2016 |
| NCT03767803 | Unknown status | Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women | October 1, 2018 | December 31, 2020 | |
| NCT02344979 | Unknown status | The Study of rHuTPO/rHuIL-11 in the Treatment for Chemotherapy-induced Thrombocytopenia in Patients With NSCLC | May 2009 | June 2015 | |
| NCT05353673 | Unknown status | Phase 2 | The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia | June 1, 2021 | February 1, 2023 |
| NCT05360134 | Unknown status | N/A | Platelet Augmentation Using C. Papaya Leaf Extract in Live Donor Liver Transplantation | January 1, 2021 | December 31, 2022 |
| NCT03838354 | Unknown status | Phase 2 | A Clinical Trial of the Low Dose Chidamide in the Management of Refractory ITP | June 1, 2019 | September 1, 2020 |
| NCT03605511 | Unknown status | TTP and aHUS in Complicated Pregnancies | September 21, 2018 | March 14, 2020 | |
| NCT03288441 | Unknown status | Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia | March 20, 2018 | December 31, 2021 | |
| NCT03617965 | Unknown status | Mortality Due to Septic Shock Associated With Thrombocytopenia | August 15, 2018 | December 31, 2019 | |
| NCT04896528 | Unknown status | Phase 2 | Efficacy and Safety of Avatrombopag in Cancer Patients With Thrombocytopenia | June 6, 2021 | December 31, 2021 |
| NCT04906083 | Unknown status | Phase 4 | Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia | February 1, 2021 | December 31, 2022 |
| NCT03633019 | Unknown status | Phase 4 | High-dose Use of rhTPO in CIT Patients | September 28, 2018 | December 31, 2020 |
| NCT03998059 | Unknown status | Evaluation of Immune Status Before and After Splenectomy in Immune Thrombocytopenia Patients | January 23, 2019 | July 23, 2022 | |
| NCT01162941 | Unknown status | Phase 2 | Efficacy of Helicobacter Pylori Eradication, Anti-D and Danazol Combination in Steroid Dependant or Refractory Immune Thrombocytopenia (ITP) | February 2010 | January 2012 |
| NCT01987791 | Unknown status | Observation Study of Prednisone and Cyclosporine in Treatment of Thrombocytopenia in Hepatitis B Cirrhosis | January 2005 | ||
| NCT01970189 | Unknown status | The International ITP Registry | January 2011 | December 2020 | |
| NCT03688191 | Unknown status | Phase 4 | Study of Sirolimus in CTD-TP in China | September 21, 2017 | September 30, 2019 |
| NCT01805648 | Unknown status | Phase 3 | Efficacy and Safety Study of Maintenance Treatment With rhTPO in Thrombocytopenic Subjects With ITP | February 2011 | December 2013 |
| NCT03701217 | Unknown status | Phase 2/Phase 3 | Eltrombopag Used in Thrombocytopenia After Comsolidation Therapy in AML | September 10, 2018 | October 2019 |
| NCT02244658 | Unknown status | Phase 3 | Recombinant Human Thrombopoietin (rhTPO) in Management of Chemotherapy-induced Thrombocytopenia in Acute Myelocytic Leukemia | September 2014 | August 2017 |
| NCT01196884 | Unknown status | Immune Thrombocytopenia (ITP) Immune-Genetic Assessment | September 2010 | ||
| NCT04797182 | Unknown status | Phase 2 | Avatrombopag for the Primary Prevention of Thrombocytopenia Induced by Cytarabine-based Chemotherapy in Patients With Lymphoma | April 2021 | July 2023 |
| NCT03968484 | Withdrawn | N/A | Platelet Transfusion in Sepsis Trial | August 1, 2020 | February 1, 2023 |
| NCT03090919 | Withdrawn | N/A | The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis | January 3, 2017 | May 31, 2021 |
| NCT04437953 | Withdrawn | Phase 2 | Avatrombopag for Thrombocytopenia in People With Cancer | May 27, 2020 | December 3, 2020 |
| NCT01660347 | Withdrawn | N/A | Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell Transplant | August 2012 | December 2014 |
| NCT01194167 | Withdrawn | Phase 2 | Study of Eltrombopag in Platelet Refractory Thrombocytopenia | August 2010 | January 2012 |
| NCT02805868 | Withdrawn | Early Phase 1 | Siltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis | June 2016 |
- Disase is a (Disease Ontology)
- DOID:2218
- Cross Reference ID (Disease Ontology)
- ICD10CM:D69.6
- Cross Reference ID (Disease Ontology)
- ICD9CM:287.5
- Cross Reference ID (Disease Ontology)
- MESH:D013921
- Cross Reference ID (Disease Ontology)
- MIM:188000
- Cross Reference ID (Disease Ontology)
- MIM:273900
- Cross Reference ID (Disease Ontology)
- MIM:300367
- Cross Reference ID (Disease Ontology)
- MIM:313900
- Cross Reference ID (Disease Ontology)
- MIM:612004
- Cross Reference ID (Disease Ontology)
- ORDO:852
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:165556002
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0040034
- HPO alt_id (Human Phenotype Ontology)
- HP:0001906
- HPO alt_id (Human Phenotype Ontology)
- HP:0004838
- HPO alt_id (Human Phenotype Ontology)
- HP:0008175
- HPO alt_id (Human Phenotype Ontology)
- HP:0008268
- HPO alt_id (Human Phenotype Ontology)
- HP:0008302
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001873
- MeSH unique ID (MeSH (Medical Subject Headings))
- D013921