chondrosarcoma (Cancer)

Search with Google Search with Bing
Information
Disease name
chondrosarcoma
Disease ID
DOID:3371
Description
"A bone sarcoma that has_material_basis_in cells derived from transformed cells that produce cartilage." [url:http\://en.wikipedia.org/wiki/Chondrosarcoma]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
EXT2 11 44,095,717 44,244,931 8
MAPK1 22 21,759,657 21,867,645 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04521686 Active, not recruiting Phase 1 Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations October 16, 2020 May 2025
NCT00496522 Active, not recruiting Phase 2 Proton Beam Therapy for Chondrosarcoma April 28, 2006 August 19, 2024
NCT03173976 Active, not recruiting Phase 1 Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial July 18, 2017 July 1, 2024
NCT04091295 Available BLESSED: Expanded Access for DeltaRex-G for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
NCT01154452 Completed Phase 1/Phase 2 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma June 2010 February 2015
NCT01330966 Completed Phase 2 Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Chondrosarcoma April 2011 February 2018
NCT02996747 Completed Low Grade Chondrosarcoma Versus Enchondroma August 2016 December 2016
NCT01553539 Completed Phase 2 Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery October 2009 January 2013
NCT01560260 Completed Phase 2 Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors March 2012 October 2015
NCT01609179 Completed N/A IPI-926 Extension Protocol for Continuation of Treatment With IPI-926 March 2012 November 2012
NCT02073994 Completed Phase 1 Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation March 1, 2014 January 4, 2024
NCT02273739 Completed Phase 1/Phase 2 Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation December 8, 2014 June 3, 2016
NCT02496741 Completed Phase 1/Phase 2 Metformin And Chloroquine in IDH1/2-mutated Solid Tumors November 2015 November 18, 2019
NCT01336803 Completed Phase 2 Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI August 2011 October 2023
NCT00004241 Completed Phase 1 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma October 1999
NCT00464620 Completed Phase 2 Trial of Dasatinib in Advanced Sarcomas May 2007 May 2017
NCT00592748 Completed Phase 1/Phase 2 Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine June 1999 May 2015
NCT03874455 No longer available Tazemetostat Expanded Access Program for Adults With Solid Tumors
NCT06029478 Not yet recruiting Understanding Engagement Trends in Chondrosarcoma Clinical Trials October 2024 October 2026
NCT06387485 Recruiting N/A A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning March 1, 2024 April 1, 2025
NCT05033288 Recruiting Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone January 20, 2022 August 30, 2028
NCT05039801 Recruiting Phase 1 IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors September 9, 2021 May 29, 2026
NCT05193188 Recruiting Phase 2 A Study of Anlotinib Combined With or Without PD-1 Antibody on Unresectable High-grade Chondrosarcoma February 6, 2023 March 31, 2026
NCT05779670 Recruiting Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery January 1, 2023 December 31, 2025
NCT05861245 Recruiting N/A Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base May 24, 2023 May 24, 2033
NCT06029218 Recruiting N/A Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy September 13, 2023 October 1, 2031
NCT03442465 Recruiting Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas February 14, 2018 February 14, 2025
NCT03715933 Recruiting Phase 1 Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas October 10, 2018 July 2026
NCT04028479 Recruiting The Registry of Oncology Outcomes Associated With Testing and Treatment May 5, 2021 October 1, 2031
NCT04040205 Recruiting Phase 2 Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration October 7, 2019 June 1, 2027
NCT04055220 Recruiting N/A Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas March 3, 2020 October 1, 2026
NCT04087902 Recruiting Long-Term Longitudinal QoL in Patients Undergoing EEA July 16, 2019 December 31, 2025
NCT04278781 Recruiting Phase 2 AG-120 in People With IDH1 Mutant Chondrosarcoma March 4, 2020 March 2026
NCT04553692 Recruiting Phase 1 Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancers September 23, 2020 August 2027
NCT04673942 Recruiting Phase 2 A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors March 29, 2021 March 1, 2027
NCT04832620 Recruiting Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas February 2, 2021 December 2027
NCT02008019 Suspended Phase 2 A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas August 14, 2014 August 2019
NCT00003292 Terminated Phase 2 S9624 Ifosfamide in Treating Patients With Meningeal Tumors July 1998 January 2004
NCT00543712 Terminated Phase 2 A Study of PRO95780 in Patients With Advanced Chondrosarcoma (APM4171g) May 31, 2007 May 5, 2008
NCT02982486 Unknown status Phase 2 A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma December 2017 December 2020
NCT01182753 Unknown status Phase 3 Trial of Proton Versus Carbon Ion Radiation Therapy in Patients With Low and Inter-mediate Grade Chondrosarcoma of the Skull Base August 2010 August 2022
NCT02587169 Unknown status Phase 1/Phase 2 Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum January 2012 December 2015
Disase is a (Disease Ontology)
DOID:0080639
Cross Reference ID (Disease Ontology)
GARD:6004
Cross Reference ID (Disease Ontology)
GARD:6055
Cross Reference ID (Disease Ontology)
ICDO:9220/3
Cross Reference ID (Disease Ontology)
MESH:D002813
Cross Reference ID (Disease Ontology)
MIM:215300
Cross Reference ID (Disease Ontology)
NCI:C2946
Cross Reference ID (Disease Ontology)
NCI:C7155
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:443520009
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:735679005
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0008479
Cross Reference ID (Disease Ontology)
UMLS_CUI:C1335473
Exact Synonym (Disease Ontology)
Cartilaginous cancer
Exact Synonym (Disease Ontology)
chondrosarcoma of bone
Exact Synonym (Disease Ontology)
primary chondrosarcoma of the bone
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0006765
OrphaNumber from OrphaNet (Orphanet)
55880
MeSH unique ID (MeSH (Medical Subject Headings))
D002813