insulinoma
Information
- Disease name
- insulinoma
- Disease ID
- DOID:3892
- Description
- "A pancreatic cystadenoma that is characterized by the overproduction of insulin." [url:https\://en.wikipedia.org/wiki/Insulinoma]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01824875 | Active, not recruiting | Phase 2 | Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors | August 8, 2013 | December 2024 |
| NCT05034783 | Active, not recruiting | Early Phase 1 | [68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients | October 1, 2021 | June 1, 2023 |
| NCT01916148 | Available | 18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia | |||
| NCT00075439 | Completed | Phase 2 | Gefitinib in Treating Patients With Progressive Metastatic Neuroendocrine Tumors | December 2003 | |
| NCT00131911 | Completed | Phase 2 | Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine Tumors | June 2005 | April 2013 |
| NCT00655655 | Completed | Phase 1 | Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors | December 2004 | January 11, 2018 |
| NCT00937079 | Completed | Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients | November 2007 | December 2011 | |
| NCT01525082 | Completed | Phase 2 | Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors | December 2012 | December 31, 2019 |
| NCT00004074 | Completed | Phase 1 | Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu | August 1999 | |
| NCT03189953 | Completed | Phase 1/Phase 2 | 68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHH | April 2015 | May 2021 |
| NCT02259725 | Completed | Phase 2 | Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors | August 16, 2016 | August 20, 2020 |
| NCT00005910 | Completed | N/A | Laparoscopy to Remove Pancreatic Tumors (Insulinomas) | June 2000 | May 2006 |
| NCT02431715 | No longer available | 18F-FDOPA PET in Neuroendocrine Tumours | |||
| NCT00001276 | Recruiting | Diagnosing and Treating Low Blood Sugar Levels | May 21, 1991 | ||
| NCT02021604 | Recruiting | Phase 1 | Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma | October 9, 2013 | June 2028 |
| NCT03583528 | Recruiting | DOTATOC PET/CT for Imaging NET Patients | July 11, 2018 | December 31, 2028 | |
| NCT04979611 | Recruiting | Phase 1 | The Clinical Application of 68Ga-NOTA-exendin-4 PET/CT in Detecting Insulinoma | August 1, 2020 | August 1, 2025 |
| NCT05523778 | Recruiting | N/A | A Multi-center Study to Evaluate the Efficacy and Safety of Pancreatic Duct Stents Placement Before the Enucleation of Insulinoma Located in the Head and Neck of the Pancreas Near the Main Pancreatic Duct | February 6, 2023 | December 2025 |
| NCT02273752 | Terminated | Phase 2 | Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer | November 2014 | December 2015 |
| NCT02031536 | Terminated | Phase 2 | Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery | April 10, 2014 | July 19, 2017 |
| NCT04452396 | Terminated | N/A | CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia | December 1, 2019 | January 31, 2023 |
| NCT00084461 | Terminated | Phase 2 | Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors | March 2004 | |
| NCT02560376 | Unknown status | Early Phase 1 | 68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis | February 2014 | December 2016 |
| NCT03930368 | Unknown status | N/A | Application of Raw Corn Starch on Patients With Insulinoma | April 15, 2019 | December 2019 |
| NCT04185350 | Unknown status | Early Phase 1 | Clinical Evaluation of 68Ga-NOTA-MAL-Cys39-exendin-4 Positron Emission Tomography in the Detection of Insulinoma | May 5, 2019 | May 5, 2020 |
| NCT02121366 | Unknown status | N/A | EUS-guided Ethanol Ablation of an Insulinoma | March 2014 | April 2018 |
| NCT02108782 | Withdrawn | Phase 2 | Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors | October 2014 | May 2015 |
| NCT03053284 | Withdrawn | Phase 2 | Pasireotide in Hyperinsulinemic Hypoglycemia | April 2017 | April 2018 |
| NCT04915144 | Withdrawn | Phase 2 | 177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETs | January 15, 2023 | December 31, 2031 |
- Disase is a (Disease Ontology)
- DOID:3918
- Cross Reference ID (Disease Ontology)
- GARD:3010
- Cross Reference ID (Disease Ontology)
- ICDO:8151/3
- Cross Reference ID (Disease Ontology)
- MESH:D007340
- Cross Reference ID (Disease Ontology)
- MESH:D007516
- Cross Reference ID (Disease Ontology)
- NCI:C65184
- Cross Reference ID (Disease Ontology)
- NCI:C95598
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:189586007
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:25324008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0021670
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0022134
- Exact Synonym (Disease Ontology)
- Insulin-Producing tumor of Islet cells
- Exact Synonym (Disease Ontology)
- Islet cell adenoma
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0012197
- OrphaNumber from OrphaNet (Orphanet)
- 97279
- MeSH unique ID (MeSH (Medical Subject Headings))
- D007340