choriocarcinoma (Cancer)

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Information
Disease name
choriocarcinoma
Disease ID
DOID:3594
Description
"A placenta cancer that has_material_basis_in trophoblastic cells." [url:https\://en.wikipedia.org/wiki/Choriocarcinoma]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
HLA-C 6 31,268,749 31,272,092 4
MLH1 3 36,993,518 37,050,846 2
KMT2C 7 152,134,925 152,436,003 2
TSC2 16 2,047,985 2,089,491 2
RAD51B 14 67,819,779 68,611,565 2
HLA-B 6 31,353,875 31,367,067 2
RNF43 17 58,353,676 58,417,533 2
CEBPA 19 33,299,934 33,302,534 2
MSH2 2 47,403,156 47,483,223 2
ZRSR2 X 15,790,484 15,823,260 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02375204 Active, not recruiting Phase 3 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors August 5, 2015 June 2024
NCT00190918 Completed Phase 2 A Trial for Patients With Gestational Trophoblastic Disease July 2006 July 2007
NCT01535053 Completed Phase 3 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia June 18, 2012 July 17, 2020
NCT02396511 Completed Phase 2 TRC105 Combined With Standard-dose Bevacizumab for Two Patients With Metastatic And Refractory Choriocarcinoma January 2015 December 2017
NCT05564026 Recruiting Molecular Epidemiology of Pediatric Germ Cell Tumors April 12, 2023 June 30, 2027
NCT04562558 Recruiting N/A Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia September 29, 2020 December 2025
NCT04684368 Recruiting Phase 2 A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT July 13, 2021 December 21, 2029
NCT02664961 Terminated Phase 2 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) March 2016 November 2018
NCT00294177 Unknown status Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma August 2006 July 2008
NCT01267851 Unknown status Clinical Database and Biobank of Patients With Gynecologic Neoplasms January 1, 2010 December 30, 2020
Disase is a (Disease Ontology)
DOID:2021
Cross Reference ID (Disease Ontology)
GARD:6059
Cross Reference ID (Disease Ontology)
ICD10CM:C58
Cross Reference ID (Disease Ontology)
ICDO:9100/3
Cross Reference ID (Disease Ontology)
MESH:D002822
Cross Reference ID (Disease Ontology)
NCI:C2948
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:189444004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0008497
Exact Synonym (Disease Ontology)
Chorioepithelioma
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0100768
MeSH unique ID (MeSH (Medical Subject Headings))
D002822