retinopathy of prematurity
Information
- Disease name
- retinopathy of prematurity
- Disease ID
- DOID:13025
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03448640 | Completed | Efficacy of Mydriatic Drops in Premature Infants | January 15, 2016 | December 15, 2017 | |
| NCT00000156 | Completed | Phase 3 | The Effects of Light Reduction on Retinopathy of Prematurity (Light-ROP) | July 1995 | |
| NCT06461975 | Completed | Phase 3 | Effect of Benoxinate Hydrochloride Eye Drops on The Premature Infant Pain Profile Score During Retinopathy of Prematurity Screening | January 1, 2023 | June 1, 2023 |
| NCT06452524 | Completed | Prematurity and Ophthalmological Changes | September 1, 2021 | May 1, 2022 | |
| NCT00233324 | Completed | Phase 3 | Surfactant Positive Airway Pressure and Pulse Oximetry Trial | February 2005 | August 2016 |
| NCT06288321 | Completed | Early Phase 1 | A Study Investigating Whether Low Dose Eyedrops for Pupil Dilation is as Effective and Safe as Standard Dose Eyedrops in Examination for Retinopathy of Prematurity. | August 10, 2022 | March 22, 2023 |
| NCT00279669 | Completed | Ultrasound to Detect Evidence for Retinal Detachment in Retinopathy of Prematurity | December 2004 | April 30, 2010 | |
| NCT06063863 | Completed | N/A | Feasibility of Nurse-led Retinal Imaging for Retinopathy of Prematurity Screening Employing the Optos California | May 10, 2021 | August 1, 2023 |
| NCT05880433 | Completed | The Effects of Mydriatic Eye Drops in Retinopathy of Prematurity Examinations | May 1, 2021 | November 30, 2022 | |
| NCT00349726 | Completed | Phase 2 | Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants | June 2006 | December 2007 |
| NCT00417404 | Completed | Phase 4 | Vitamin A and Very Low Birthweight Babies (VitAL) | January 2007 | December 2009 |
| NCT00427063 | Completed | Heredity of Retinal Vessel Tortuosity | January 1998 | December 1998 | |
| NCT05712642 | Completed | Phase 3 | A Dosing Study of Intravitreal Bevacizumab for Retinopathy of Prematurity | February 1, 2020 | January 28, 2021 |
| NCT05701124 | Completed | Phase 3 | Intravitreal Ranibizumab Injection for Aggressive Versus Type 1 Prethreshold Retinopathy of Prematurity | November 20, 2020 | November 20, 2022 |
| NCT05152862 | Completed | Improve Screening Criteria for Retinopathy of Prematurity in Two French Center | March 21, 2022 | June 16, 2022 | |
| NCT00623220 | Completed | Phase 3 | Inhaled Nitrous Oxide for Pain Relief During Eye Exam in the Pre-term Infant | March 2008 | April 2010 |
| NCT05099588 | Completed | The Incidence of Treatment-requiring Retinopathy of Prematurity in Greece | June 1, 2020 | January 15, 2023 | |
| NCT00648687 | Completed | N/A | Pain Response During Examination for Retinopathy of Prematurity | March 2008 | June 2010 |
| NCT05043077 | Completed | Phase 4 | Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening | September 7, 2021 | January 23, 2023 |
| NCT00845624 | Completed | Time Outside Target Oxygen Saturation Range in Preterm Infants and Long Term Outcomes and Preterm Infants | January 2007 | June 2009 | |
| NCT00000133 | Completed | N/A | Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity | January 1986 | August 2003 |
| NCT00872664 | Completed | N/A | Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids | September 2009 | June 2013 |
| NCT00895869 | Completed | Pain in Neonates During Screening for Retinopathy of Prematurity Using Two Methods | April 2004 | February 2008 | |
| NCT04883931 | Completed | N/A | Mother Milk as a Eye Drop & Premature Retinopathy | May 6, 2021 | January 20, 2022 |
| NCT00921544 | Completed | Phase 4 | Sucrose Analgesia for the Reduction of Pain During Retinopathy of Prematurity Screening | August 2008 | March 2009 |
| NCT01030575 | Completed | Phase 2 | Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2) | January 2010 | September 2013 |
| NCT01079715 | Completed | Phase 2/Phase 3 | Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity | January 2010 | October 2012 |
| NCT01124331 | Completed | N/A | Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis | March 2005 | August 2014 |
| NCT01203436 | Completed | Phase 2/Phase 3 | Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity | February 1994 | March 1999 |
| NCT04838665 | Completed | Phase 4 | Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study | September 30, 2011 | September 30, 2011 |
| NCT01238471 | Completed | Phase 1/Phase 2 | Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study | May 2010 | July 2012 |
| NCT01264276 | Completed | Telemedicine Approaches to Evaluating Acute-phase ROP | July 2011 | January 2014 | |
| NCT04767178 | Completed | Pain Management During Screening for Retinopathy of Prematurity | January 1, 2020 | August 15, 2020 | |
| NCT04623684 | Completed | Phase 4 | Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial | March 24, 2020 | September 29, 2020 |
| NCT01363960 | Completed | Retinopathy of Prematurity:Summary of a Decade | March 1999 | December 2010 | |
| NCT01559571 | Completed | Registry for Severe ROP and Treatment on Visual Outcomes | May 2012 | May 15, 2020 | |
| NCT01780155 | Completed | Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity | June 24, 2013 | August 1, 2020 | |
| NCT01861470 | Completed | REDEXAM - Reducing Painful Eye Examinations in Preterm Infants | November 2013 | July 2015 | |
| NCT04621136 | Completed | Phase 1/Phase 2 | PhaseI/II Investigator-Initiated Trial to Investigate Safety and Efficacy of Ripasudil in Patients With Retinopathy of Prematurity | November 1, 2020 | December 31, 2022 |
| NCT01875510 | Completed | N/A | The Influence of Fish-oil Lipid Emulsions on Neonatal Morbidities | January 2013 | November 2013 |
| NCT02014454 | Completed | Phase 2 | Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature | November 2013 | August 2014 |
| NCT04539106 | Completed | Intravitreal Ranibizumab in Recurrent ROP | June 1, 2019 | February 1, 2020 | |
| NCT04537065 | Completed | Long Term Outcome of Intravitreal Ranibizumab for ROP | April 1, 2018 | September 1, 2018 | |
| NCT02102711 | Completed | N/A | Oral Vitamin A Supplementation in Neonates With Birth Weight < 1500 g | April 2014 | April 2016 |
| NCT02157727 | Completed | Cost-effectiveness of Tele-expertise for Premature Infants for Retinopathy | January 2014 | October 2015 | |
| NCT02164604 | Completed | N/A | Lucentis to Treat Retinopathy of Prematurity (ROP) 3 Plus Disease | January 2011 | October 2013 |
| NCT04408807 | Completed | N/A | Stress Induced by Screening for Retinopathy of Prematurity - Should Speculum and Indentation Rather be Avoided | September 3, 2019 | February 27, 2020 |
| NCT02344225 | Completed | Phase 2 | Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study) | January 1, 2015 | June 30, 2018 |
| NCT02375971 | Completed | Phase 3 | RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity | December 30, 2015 | December 14, 2017 |
| NCT02390531 | Completed | Phase 1 | Phase 1 Trial of Bevacizumab Treatment for Severe Retinopathy of Prematurity | April 28, 2015 | May 11, 2021 |
| NCT02484989 | Completed | UK Surveillance of Treated Retinopathy of Prematurity | May 2013 | July 2015 | |
| NCT02486042 | Completed | Phase 2 | Omega-3 Long Chain Polyunsaturated Fatty Acid (LCPUFA) Supplementation in Very Low Birth Weight Infants for The Prevention Retinopathy of Prematurity | March 2014 | December 2019 |
| NCT02504944 | Completed | Phase 2 | Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%) | July 2015 | August 2018 |
| NCT04101721 | Completed | Phase 3 | Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity | October 30, 2019 | August 18, 2022 |
| NCT02683317 | Completed | N/A | Enteral Administration of Docosahexaenoic Acid to Prevent Retinopathy of Prematurity | February 22, 2016 | October 31, 2017 |
| NCT02760472 | Completed | Phase 3 | A Fatty Acids Study in Preventing Retinopathy of Prematurity | March 2013 | September 2015 |
| NCT02780544 | Completed | N/A | Infant-parent Skin-to-skin Contact During Screening for Retinopathy | January 2014 | June 2016 |
| NCT02814929 | Completed | Incidence, Risk Factors and Severity of Retinopathy of Prematurity (ROP) in Turkey | April 1, 2016 | October 17, 2017 | |
| NCT02820662 | Completed | N/A | Study of the Implication of Omega-3 Polyunsaturated Fatty Acids in Retinopathy of Prematurity in New-born Infants | July 30, 2015 | |
| NCT02887157 | Completed | Analyzing Retinal Microanatomy in ROP | July 22, 2016 | April 15, 2021 | |
| NCT04092127 | Completed | Pain of Premature Babies and RetCam (DOLICAM) | November 12, 2019 | June 15, 2020 | |
| NCT03824782 | Completed | N/A | The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination | April 1, 2016 | June 30, 2017 |
| NCT03650621 | Completed | N/A | Acupuncture for Preterm Infants Requiring Eye-exam | August 24, 2018 | April 30, 2020 |
| NCT03154723 | Completed | N/A | Effects of Early Vitamin A Supplementation on the Risk for Retinopathy of Prematurity in Extremely Preterm Infants | August 1, 2015 | December 31, 2017 |
| NCT03274596 | Completed | N/A | Effect of Vitamin E for Prevention of Retinopathy of Prematurity: A Randomized Clinical Trial. | March 1, 2013 | December 1, 2015 |
| NCT03334513 | Completed | Refractive Error and Biometry in Retinopathy of Prematurity | April 1, 2011 | April 1, 2014 | |
| NCT03347799 | Completed | WINROP Algorithm Validation for Retinopathy Screening in a Cohort of Premature Infants | July 1, 2012 | September 1, 2017 | |
| NCT04985448 | Enrolling by invitation | Real World Study of the Effectiveness and Safety of Conbercept Ophthalmic Injection in the Treatment of Retinopathy of Prematurity - Multicenter, Retrospective and Observational Study Based on Real World Data | September 2022 | October 2022 | |
| NCT04515524 | Enrolling by invitation | Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next) | February 16, 2021 | November 4, 2026 | |
| NCT05144282 | Enrolling by invitation | The Analysis of Association of Retinopathy of Prematurity, Gut Microbiome Profile, and Systemic Inflammation | August 15, 2020 | July 31, 2023 | |
| NCT00870636 | No longer available | Use of Pan-vascular Endothelial Growth Factor Receptor (Pan-VEGF) Blockade for the Treatment of Retinopathy of Prematurity (ROP) (Compassionate Use BLOCK-ROP) | |||
| NCT06348641 | Not yet recruiting | N/A | Reducing Pain and Increasing Comfort During a Retinopathy of Prematurity Examination | April 20, 2024 | April 20, 2025 |
| NCT06067958 | Not yet recruiting | Phase 3 | Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity | January 2024 | April 2025 |
| NCT05629910 | Not yet recruiting | N/A | NeO2Matic-Pilot Trial | January 1, 2024 | July 1, 2025 |
| NCT05558059 | Not yet recruiting | Imaging Retinal Vasculature in Infant Eyes | August 2024 | August 31, 2027 | |
| NCT03083431 | Recruiting | Phase 2 | Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity | September 22, 2022 | July 2026 |
| NCT04420156 | Recruiting | Clinical and Genetic Analysis of ROP | July 1, 2011 | May 31, 2030 | |
| NCT04634578 | Recruiting | Phase 2 | Bevacizumab Treatment For Type 1 ROP | May 18, 2022 | December 2026 |
| NCT04902859 | Recruiting | Phase 4 | Clonidine as Pain Relief During ROP Eye Examinations | April 25, 2022 | December 31, 2024 |
| NCT04939571 | Recruiting | European Disease Registry on Retinopathy of Prematurity (ROP) | August 6, 2021 | August 2039 | |
| NCT04995341 | Recruiting | N/A | Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) | August 16, 2021 | March 31, 2026 |
| NCT05100212 | Recruiting | Phase 2 | umBilical Or Adult Donor Red Blood Cells in Extremely Low Gestational Age Neonates and Retinopathy of Prematurity (BORN) | December 1, 2021 | December 2024 |
| NCT05132257 | Recruiting | Genetic Polymorphism and Retinopathy of Prematurity: Correlation of Clinical Presentations and Severity | April 12, 2021 | March 31, 2024 | |
| NCT05133999 | Recruiting | Iron and Retinopathy of Prematurity (ROP) | April 28, 2022 | September 2025 | |
| NCT05304949 | Recruiting | Regulatory PMS Study for Lucentis® in Patients With Retinopathy of Prematurity | June 22, 2022 | January 12, 2025 | |
| NCT05387941 | Recruiting | Phase 1 | Pharmacokinetics and Safety of Dexamethasone Eye Drops in Preterm Infants | June 14, 2022 | December 2028 |
| NCT05576792 | Recruiting | A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China | January 13, 2023 | December 30, 2024 | |
| NCT05705258 | Recruiting | A Study to Collect Data on the Use of Eylea in Babies Born Too Early Who Have a Condition of the Eye Where Blood Vessels Grow Abnormally in the Retina (Retinopathy of Prematurity) | March 27, 2023 | March 30, 2027 | |
| NCT05967572 | Recruiting | N/A | The Effect of Different Music Listened During Retinopathy Examination to Premature Infants | June 1, 2023 | July 1, 2024 |
| NCT06044181 | Recruiting | N/A | Peripheral Avascular Retina in Retinopathy of Prematurity | January 1, 2024 | November 1, 2025 |
| NCT06109285 | Recruiting | N/A | Validation of i-ROP DL to Detect More Than Mild ROP | November 29, 2023 | August 2024 |
| NCT06265363 | Recruiting | Evaluation of the Frequency, Risk Factors, and Outcomes of ROP in Infants With a BW >1500 Grs or GA ≥33 Wks in Turkey. | August 1, 2023 | November 1, 2024 | |
| NCT06315556 | Recruiting | An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK) | March 5, 2024 | April 30, 2027 | |
| NCT00702819 | Terminated | Phase 1 | Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity | June 2008 | July 2009 |
| NCT01335113 | Terminated | A Scan Ultrasonography in the Evaluation of Retinopathy of Prematurity | October 2010 | October 1, 2015 | |
| NCT00500396 | Terminated | Phase 4 | Vascular Endothelial Growth Factor in Stage V ROP | March 2007 | June 2007 |
| NCT04634604 | Terminated | Phase 3 | A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP | April 27, 2022 | August 14, 2023 |
| NCT01266824 | Terminated | N/A | Proparacaine and Mydriatic Eye Drops | December 2010 | August 2011 |
| NCT00634972 | Terminated | Phase 4 | Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity | November 2005 | August 2008 |
| NCT02257307 | Terminated | Telemedicine Approaches to Evaluating Acute-Phase ROP eROP Implementation Project | July 2014 | March 16, 2016 | |
| NCT00161694 | Terminated | N/A | Use of Sucrose to Relieve Pain During Eye Exams in Infants | July 2005 | |
| NCT02977000 | Unknown status | N/A | Oral Propranolol Improve Retinopathy of Prematurity Outcomes in Very Preterm Infants | May 2016 | May 2018 |
| NCT04191954 | Unknown status | Phase 2/Phase 3 | Fasudil Eye Drop in Retinopathy Of Prematurity(ROP) | June 2, 2019 | September 2020 |
| NCT04050488 | Unknown status | Phase 4 | Zinc Supplementation on Very Low Birth Weight Infant | August 20, 2019 | July 31, 2020 |
| NCT05010252 | Unknown status | N/A | The Effect of Cycled Light on Premature Infants and Mothers | April 16, 2021 | February 2022 |
| NCT02090322 | Unknown status | N/A | Bevacizumab 0.500MG Intravitreal There Isn't Lower Than 0.625MG in the Treatment of ROP Type 1 | September 2013 | March 2014 |
| NCT02050971 | Unknown status | Phase 1 | Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates | October 2010 | December 2015 |
| NCT01872871 | Unknown status | N/A | The Efficacy of Paracetamol in Reducing Pain During Ophthalmological Examination for Retinopathy of Prematurity: a Prospective Randomised Trial | January 2013 | January 2014 |
| NCT04769661 | Unknown status | Role of Cord Blood Cytokines and Perinatal Factors in Prediction of Retinopathy of Prematurity | May 1, 2021 | December 30, 2022 | |
| NCT00910234 | Unknown status | Phase 1/Phase 2 | Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants | August 2009 | July 2011 |
| NCT04519060 | Unknown status | N/A | Eye Shields for Infants After Dilated Exam | February 1, 2021 | December 2021 |
| NCT00346814 | Unknown status | Phase 2/Phase 3 | Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome | July 2006 | November 2006 |
| NCT00254176 | Unknown status | Phase 2/Phase 3 | Cysteine Supplementation in Critically Ill Neonates | September 2006 | July 2011 |
| NCT03038295 | Unknown status | Phase 2 | a Prospective Cohort Study for Propranolol Treatment in Retinopathy of Prematurity | March 2017 | December 2019 |
| NCT00027222 | Unknown status | Phase 2/Phase 3 | The Early Treatment for Retinopathy of Prematurity Study (ETROP) | October 2001 | |
| NCT00622726 | Unknown status | Phase 2 | Bevacizumab Eliminates the Angiogenic Threat for Retinopathy of Prematurity | March 2008 | August 2020 |
| NCT05186155 | Unknown status | Analysis of Ocular and Neurodevelopmental Function for Retinopathy of Prematurity | January 1, 2019 | March 31, 2022 | |
| NCT00339001 | Unknown status | Erythropoietin and Early Iron Supplement and Retinopathy of Prematurity | April 2006 | December 2006 | |
| NCT00563121 | Withdrawn | Phase 4 | VEGF Levels in Aqueous, Vitreous and Subretinal Fluid in ROP Stage IV and V | March 2007 | June 2007 |
| NCT03399825 | Withdrawn | Optical Coherence Tomography Angiography (OCT-A) in Children (≥ 6 <14 Years of Age) | January 2018 | March 1, 2018 | |
| NCT01232777 | Withdrawn | Phase 2 | Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity (BLOCK-ROP) | June 2012 | July 2018 |
| NCT02655432 | Withdrawn | Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population | January 2016 | June 2016 |
- Disase is a (Disease Ontology)
- DOID:5679
- Cross Reference ID (Disease Ontology)
- GARD:5695
- Cross Reference ID (Disease Ontology)
- ICD10CM:H35.1
- Cross Reference ID (Disease Ontology)
- ICD9CM:362.21
- Cross Reference ID (Disease Ontology)
- MESH:D012178
- Cross Reference ID (Disease Ontology)
- NCI:C34982
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:155110004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0035344
- Exact Synonym (Disease Ontology)
- premature retinopathy
- Exact Synonym (Disease Ontology)
- Retrolental fibroplasia
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0500049
- OrphaNumber from OrphaNet (Orphanet)
- 90050
- ICD10 preferred id (Insert disease from ICD10)
- D0006166
- ICD10 class code (Insert disease from ICD10)
- H35.1
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012178