chr12:68154768:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr12:68,548,548-68,553,520 |
| hg38 | chr12:68,154,768-68,159,740 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.009 | squamous cell carcinoma | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Carcinoma, Transitional Cell | NA | BeFree | Detail | |
| 0.008 | Cardiovascular Diseases | NA | BeFree,GAD | Detail | |
| 0.002 | carotid stenosis | NA | GAD | Detail | |
| 0.015 | celiac disease | Systematic annotation of celiac disease loci refines pathological pathways and s... | BeFree,GAD,LHGDN | 25190711 | Detail |
| 0.015 | celiac disease | The aims of this study were to ascertain whether five SNPs in the TNFA promoter ... | BeFree,GAD,LHGDN | 25915602 | Detail |
| <0.001 | Cerebellar Diseases | NA | BeFree | Detail | |
| 0.004 | Malignant tumor of cervix | IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P <... | BeFree | 25106529 | Detail |
| 0.004 | Malignant tumor of cervix | Methylation patterns of the IFN-γ gene in cervical cancer tissues. | BeFree | 25208560 | Detail |
| 0.004 | Malignant tumor of cervix | B7-H4 is overexpressed in human cervical cancers, and it is associated with lowe... | BeFree | 25446402 | Detail |
| 0.004 | Malignant tumor of cervix | Interferon gamma +874 T/A polymorphism increases the risk of cervical cancer: ev... | BeFree | 25649976 | Detail |
| 0.004 | Malignant tumor of cervix | Association Study of Single-Nucleotide Polymorphisms of STAT2/STAT3/IFN-γ Genes ... | BeFree | 25921106 | Detail |
| 0.003 | Uterine Cervical Neoplasm | Furthermore, the mRNA expression of IFN-γ in cervical tumors with methylation (0... | BeFree,GAD | 25208560 | Detail |
| 0.002 | Chagas Cardiomyopathy | NA | GAD | Detail | |
| 0.123 | Chlamydia Infections | NA | BeFree,CTD_human,GAD | Detail | |
| <0.001 | cholangitis | NA | BeFree | Detail | |
| 0.002 | Primary biliary cirrhosis | NA | BeFree | Detail | |
| 0.003 | choriocarcinoma | NA | BeFree,LHGDN | Detail | |
| 0.003 | chorioretinitis | NA | BeFree,GAD | Detail | |
| <0.001 | chronic rhinitis | NA | BeFree | Detail | |
| 0.002 | clonorchiasis | NA | GAD | Detail | |
| <0.001 | coccidioidomycosis | NA | BeFree | Detail | |
| 0.124 | colitis | Here, we show that the NF-κB protein c-Rel regulates the inflammatory potential ... | BeFree,CTD_human | 25100292 | Detail |
| 0.124 | colitis | SEW2871 treatment attenuated established colitis associated with decreased CD4+ ... | BeFree,CTD_human | 25588868 | Detail |
| <0.001 | Colonic Diseases | In addition, IL-10 KO mice receiving Bifico treatment had reduced mucosal secret... | BeFree | 24782616 | Detail |
| 0.120 | Colonic Neoplasms | NA | CTD_human | Detail | |
| 0.004 | colorectal carcinoma | A subset of colorectal cancer displayed high infiltration with activated CD8(+) ... | BeFree | 25358689 | Detail |
| 0.004 | colorectal carcinoma | Deficiency of interferon-gamma or its receptor promotes colorectal cancer develo... | BeFree | 25383957 | Detail |
| 0.004 | colorectal carcinoma | A positive feedback loop between IRF1 and miR-29b may contribute to the sensitiv... | BeFree | 25592039 | Detail |
| 0.004 | colorectal carcinoma | We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 l... | BeFree | 25671296 | Detail |
| 0.004 | colorectal carcinoma | Our results demonstrate that ATG5 plays important roles in intestinal tumor grow... | BeFree | 25695667 | Detail |
| 0.003 | Colorectal Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.007 | common cold | NA | GAD | Detail | |
| 0.006 | common variable immunodeficiency | NA | BeFree,GAD | Detail | |
| <0.001 | Condylomata Acuminata | NA | BeFree | Detail | |
| 0.080 | allergic conjunctivitis | NA | RGD | Detail | |
| 0.002 | Connective Tissue Diseases | NA | GAD | Detail | |
| 0.003 | Coronary Arteriosclerosis | NA | BeFree,GAD | Detail | |
| 0.003 | Coronary heart disease | NA | BeFree,GAD | Detail | |
| <0.001 | cowpox | NA | BeFree | Detail | |
| <0.001 | cryoglobulinemia | NA | BeFree | Detail | |
| <0.001 | cryptosporidiosis | NA | BeFree | Detail | |
| 0.004 | cystic fibrosis | Our data demonstrate a pronounced reduction of HLA-DQ expression in CF, which is... | BeFree,LHGDN | 25146850 | Detail |
| 0.003 | Cytomegalovirus Infections | Interferon-gamma gene polymorphism +874 A/T is associated with an increased risk... | BeFree,GAD | 25208755 | Detail |
| 0.003 | Cessation of life | NA | LHGDN | Detail | |
| <0.001 | Hepatitis D Infection | NA | BeFree | Detail | |
| <0.001 | Demyelinating Diseases | NA | BeFree | Detail | |
| <0.001 | Dengue Fever | However, while DENV-NS3 specific T cells of those with mild/sub clinical dengue ... | BeFree | 25875020 | Detail |
| 0.001 | Mental Depression | NA | BeFree | Detail | |
| 0.001 | depressive disorder | NA | BeFree | Detail | |
| <0.001 | dermatitis | NA | BeFree | Detail | |
| <0.001 | dermatitis herpetiformis | NA | BeFree | Detail | |
| <0.001 | Drug Eruptions | NA | BeFree | Detail | |
| 0.132 | Dermatitis, Atopic | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | contact dermatitis | NA | BeFree | Detail | |
| <0.001 | dermatophytosis | NA | BeFree | Detail | |
| <0.001 | scleroderma | NA | BeFree | Detail | |
| 0.003 | Diabetes | NA | BeFree | Detail | |
| 0.008 | diabetes mellitus | NA | BeFree,GAD | Detail | |
| 0.200 | Diabetes Mellitus, Experimental | NA | CTD_human,RGD | Detail | |
| 0.227 | Diabetes Mellitus, Insulin-Dependent | Type 1 Diabetes (T1D) is an autoimmune disease where local release of cytokines ... | BeFree,CTD_human,GAD,MGD | 24462878 | Detail |
| 0.227 | Diabetes Mellitus, Insulin-Dependent | The results revealed that the DM1-preventing function was in part caused by a re... | BeFree,CTD_human,GAD,MGD | 25157497 | Detail |
| 0.227 | Diabetes Mellitus, Insulin-Dependent | T cells secreting the cytokines IFN-γ and IL-10 in response to seven peptides kn... | BeFree,CTD_human,GAD,MGD | 25225671 | Detail |
| 0.006 | Diabetes Mellitus, Non-Insulin-Dependent | We investigated in 102 T2D patients the association of the cytokine polymorphism... | BeFree,GAD | 26064986 | Detail |
| <0.001 | Down syndrome | NA | BeFree | Detail | |
| 0.002 | drug allergy | NA | GAD | Detail | |
| <0.001 | Shigella Infections | NA | BeFree | Detail | |
| 0.007 | Eczema | NA | BeFree | Detail | |
| 0.003 | Pathological accumulation of air in tissues | NA | LHGDN | Detail | |
| <0.001 | encephalitis | NA | BeFree | Detail | |
| 0.004 | Experimental Autoimmune Encephalomyelitis | Importantly, high IL-7 expression was detected in the CNS during EAE and could d... | BeFree | 26223651 | Detail |
| 0.012 | endometriosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.080 | endophthalmitis | NA | RGD | Detail | |
| 0.120 | Entamoebiasis | NA | CTD_human | Detail | |
| 0.002 | Enterobacteriaceae Infections | NA | GAD | Detail | |
| <0.001 | Enterovirus Infections | NA | BeFree | Detail | |
| <0.001 | Eosinophilia | Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total c... | BeFree | 24655063 | Detail |
| <0.001 | Toxic Epidermal Necrolysis | NA | BeFree | Detail | |
| <0.001 | epidermodysplasia verruciformis | NA | BeFree | Detail | |
| 0.002 | Equine Infectious Anemia | NA | GAD | Detail | |
| <0.001 | Erythema Chronicum Migrans | NA | BeFree | Detail | |
| <0.001 | erythema multiforme | NA | BeFree | Detail | |
| 0.005 | Esophageal Neoplasms | NA | BeFree,GAD | Detail | |
| 0.001 | Exanthema | NA | BeFree | Detail | |
| 0.003 | Disorder of eye | NA | BeFree,LHGDN | Detail | |
| <0.001 | Eye Infections | NA | BeFree | Detail | |
| 0.120 | Eyelid Diseases | NA | CTD_human | Detail | |
| 0.005 | Fanconi anemia | NA | BeFree,LHGDN | Detail | |
| <0.001 | Fatigue | Pro-inflammatory and antiviral cytokines (granulocyte macrophage colony stimulat... | BeFree | 25062274 | Detail |
| 0.002 | chronic fatigue syndrome | NA | GAD | Detail | |
| 0.002 | Fetal Diseases | NA | GAD | Detail | |
| 0.120 | Fever | NA | CTD_human | Detail | |
| <0.001 | fibrosarcoma | NA | BeFree | Detail | |
| 0.011 | Fibrosis | NA | GAD,LHGDN | Detail | |
| <0.001 | filariasis | NA | BeFree | Detail | |
| <0.001 | Fowlpox | NA | BeFree | Detail | |
| <0.001 | Friedreich ataxia | NA | BeFree | Detail | |
| 0.003 | gastritis | NA | BeFree,GAD | Detail | |
| 0.001 | Gingival Diseases | Th1-polarized host response, mediated by IFN-γ, has been associated with increas... | BeFree | 25832120 | Detail |
| 0.002 | Gingival Hemorrhage | NA | GAD | Detail | |
| <0.001 | gingivitis | NA | BeFree | Detail | |
| 0.006 | glioblastoma | NA | BeFree,LHGDN | Detail | |
| 0.083 | Glioma | NA | BeFree,RGD | Detail | |
| 0.120 | glomerulonephritis | NA | BeFree,CTD_human | Detail | |
| 0.012 | IgA glomerulonephritis | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | membranous glomerulonephritis | NA | BeFree | Detail | |
| <0.001 | Glossitis, Benign Migratory | NA | BeFree | Detail | |
| 0.149 | Graft-vs-Host Disease | Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD c... | BeFree,CTD_human,GAD,LHGDN | 25774595 | Detail |
| 0.149 | Graft-vs-Host Disease | Alloantigen-induced IL-18 receptor upregulation was lower in st2(-/-) T cells, a... | BeFree,CTD_human,GAD,LHGDN | 25814531 | Detail |
| 0.149 | Graft-vs-Host Disease | IL-6, IL-9, CCL24, CCL18, IL-10, IFN-γ, and CCL2 were highly increased (>6-fold)... | BeFree,CTD_human,GAD,LHGDN | 26200497 | Detail |
| 0.003 | Granuloma | NA | LHGDN | Detail | |
| 0.007 | chronic granulomatous disease | NA | BeFree | Detail | |
| 0.009 | Graves Disease | NA | BeFree,GAD | Detail | |
| <0.001 | Hamartoma Syndrome, Multiple | NA | BeFree | Detail | |
| <0.001 | Hay fever | NA | BeFree | Detail | |
| 0.120 | cardiac arrest | NA | CTD_human | Detail | |
| 0.123 | Heart failure | NA | BeFree,CTD_human,GAD | Detail | |
| <0.001 | Atrial Septal Defects | NA | BeFree | Detail | |
| <0.001 | Helminthiasis | These data demonstrate a new mechanism by which helminth infection and the produ... | BeFree | 24837622 | Detail |
| 0.002 | Hematological Disease | NA | GAD | Detail | |
| <0.001 | hemochromatosis | NA | BeFree | Detail | |
| <0.001 | Hemorrhagic Fever, Crimean | NA | BeFree | Detail | |
| 0.002 | Severe Dengue | NA | GAD | Detail | |
| 0.121 | hepatitis | NA | BeFree,CTD_human | Detail | |
| <0.001 | hepatitis A | NA | BeFree | Detail | |
| 0.161 | hepatitis B | The study indicated that low IFN-γ expression probably impairs host immune respo... | BeFree,CTD_human,GAD,LHGDN | 24446686 | Detail |
| 0.161 | hepatitis B | The frequency of CD4(+) interferon-γ-positive T cells was negatively associated ... | BeFree,CTD_human,GAD,LHGDN | 24773272 | Detail |
| 0.161 | hepatitis B | Circulating CD56dim natural killer cells and CD56+ T cells that produce interfer... | BeFree,CTD_human,GAD,LHGDN | 25186004 | Detail |
| 0.161 | hepatitis B | Furthermore, we found that these cells could suppress hepatitis B virus-specific... | BeFree,CTD_human,GAD,LHGDN | 25344470 | Detail |
| 0.161 | hepatitis B | HBV‑specific interferon‑γ enzyme‑linked immunospot (IFN‑γ ELISPOT) assay and HBV... | BeFree,CTD_human,GAD,LHGDN | 25371014 | Detail |
| 0.161 | hepatitis B | IFN-γ +874A/T polymorphism also increased HBV-induced HCC risk (OR=1.42; 95% CI ... | BeFree,CTD_human,GAD,LHGDN | 25739411 | Detail |
| 0.001 | Hepatitis, Chronic | NA | BeFree | Detail | |
| 0.005 | Herpes Simplex Infections | NA | BeFree,LHGDN | Detail | |
| <0.001 | Herpesviridae Infections | NA | BeFree | Detail | |
| 0.003 | Histiocytosis, Langerhans-Cell | NA | BeFree,GAD | Detail | |
| 0.166 | HIV Infections | Depending on KIR2DS4 expression (presence or absence) on cell surface, NK cells ... | BeFree,CTD_human,GAD,LHGDN | 24901871 | Detail |
| 0.166 | HIV Infections | Following qRT-PCR setup and run, the level of human IFN-γ transcript is normaliz... | BeFree,CTD_human,GAD,LHGDN | 25149303 | Detail |
| 0.166 | HIV Infections | Vaccine recipients with undetectable residual viremia at week 8 had higher frequ... | BeFree,CTD_human,GAD,LHGDN | 25254301 | Detail |
| 0.166 | HIV Infections | The A to G hyper-mutation pattern observed in ADAR1 over-expressing cells in vit... | BeFree,CTD_human,GAD,LHGDN | 25272020 | Detail |
| 0.166 | HIV Infections | Immune-correlates analysis of an HIV-1 vaccine efficacy trial reveals an associa... | BeFree,CTD_human,GAD,LHGDN | 25369172 | Detail |
| 0.166 | HIV Infections | We demonstrate antigen-specific upregulation of IFNγ and IL-2 mRNAs in HIV- and ... | BeFree,CTD_human,GAD,LHGDN | 25472703 | Detail |
| 0.166 | HIV Infections | Patient HLA-type, longitudinal CD8+ T-cell responses measured by IFN-γ ELISpot a... | BeFree,CTD_human,GAD,LHGDN | 25642847 | Detail |
| 0.166 | HIV Infections | Polymorphisms in the IFNγ, IL-10, and TGFβ genes may be associated with HIV-1 in... | BeFree,CTD_human,GAD,LHGDN | 25802474 | Detail |
| 0.166 | HIV Infections | Contribution of a heparin-binding haemagglutinin interferon-gamma release assay ... | BeFree,CTD_human,GAD,LHGDN | 25886172 | Detail |
| 0.166 | HIV Infections | Following IL-12 stimulation, IFNγ expression was lower in HIV-HPgV co-infected s... | BeFree,CTD_human,GAD,LHGDN | 26245365 | Detail |
| 0.166 | HIV Infections | HIV-specific CD8(+) T cells secreted little interferon-γ, underwent rapid apopto... | BeFree,CTD_human,GAD,LHGDN | 26362266 | Detail |
| 0.006 | Hodgkin Disease | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Hyperbilirubinemia | The CART-33 infusion alone induced rigorous chills and fevers; drastic fluctuati... | BeFree | 25174587 | Detail |
| <0.001 | hypercalcemia | NA | BeFree | Detail | |
| <0.001 | Hypergammaglobulinemia | IFN-γ inhibited cTFH cell function in vitro and in vivo, as corroborated by hype... | BeFree | 26162572 | Detail |
| 0.003 | hyperglycemia | NA | BeFree,GAD | Detail | |
| <0.001 | hyperinsulinism | NA | BeFree | Detail | |
| 0.122 | Hypersensitivity | NA | CTD_human,GAD | Detail | |
| 0.002 | Immediate hypersensitivity | NA | GAD | Detail | |
| <0.001 | Hypertensive disease | Expression of interferon-γ in decidual natural killer cells from women with hype... | BeFree | 24246020 | Detail |
| 0.120 | Hyponatremia | NA | CTD_human | Detail | |
| 0.120 | Hypotension | NA | CTD_human | Detail | |
| 0.120 | Immune Complex Diseases | NA | CTD_human | Detail | |
| <0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
| 0.001 | Immune System Diseases | NA | BeFree | Detail | |
| 0.003 | infectious mononucleosis | NA | BeFree,GAD | Detail | |
| 0.002 | Female infertility | NA | GAD | Detail | |
| 0.153 | Inflammation | NA | CTD_human,GAD,LHGDN | Detail | |
| 0.003 | influenza | In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and pro... | BeFree | 25033426 | Detail |
| 0.003 | influenza | In contrast, CMV-seropositive young adults exhibited enhanced antibody responses... | BeFree | 25834109 | Detail |
| 0.003 | influenza | The cross-reactivity of influenza B virus-specific polyclonal CD8+ cytotoxic T-l... | BeFree | 25900135 | Detail |
| <0.001 | Intestinal Diseases | NA | BeFree | Detail | |
| <0.001 | Intestinal Neoplasms | Here, we investigated the role of endogenous IFN-γ deficiency in adenomatous pol... | BeFree | 25383957 | Detail |
| <0.001 | Intestinal Neoplasms | Our results demonstrate that ATG5 plays important roles in intestinal tumor grow... | BeFree | 25695667 | Detail |
| 0.007 | Kidney Diseases | NA | GAD | Detail | |
| <0.001 | Kidney Failure, Acute | Frequency of TGF- β and IFN- γ genotype as risk factors for acute kidney injury ... | BeFree | 25147823 | Detail |
| 0.003 | Kidney Failure, Chronic | NA | BeFree,GAD | Detail | |
| 0.120 | Legionnaires' disease | NA | CTD_human | Detail | |
| 0.127 | leishmaniasis | The redirection of the immune response elicited against the LiPABP family (from ... | BeFree,CTD_human,LHGDN | 25955652 | Detail |
| 0.124 | Leishmaniasis, Cutaneous | NA | BeFree,CTD_human,GAD | Detail | |
| <0.001 | Infection by Leishmania braziliensis | NA | BeFree | Detail | |
| 0.123 | Leishmaniasis, Visceral | Evaluation of IFN-γ polymorphism in visceral leishmaniasis. | BeFree,CTD_human | 24728749 | Detail |
| 0.123 | Leishmaniasis, Visceral | Leishmania specific CD4 T cells release IFNγ that limits parasite replication in... | BeFree,CTD_human | 25275531 | Detail |
| 0.123 | Leishmaniasis, Visceral | The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated ... | BeFree,CTD_human | 25449949 | Detail |
| 0.123 | Leishmaniasis, Visceral | Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-az... | BeFree,CTD_human | 25466928 | Detail |
| 0.008 | leprosy | NA | BeFree,GAD | Detail | |
| 0.002 | leptospirosis | NA | GAD | Detail | |
| 0.005 | leukemia | NA | BeFree,GAD | Detail | |
| 0.008 | chronic lymphocytic leukemia | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | hairy cell leukemia | NA | BeFree | Detail | |
| <0.001 | lymphoid leukemia | NA | BeFree | Detail | |
| 0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Leukemia, Lymphocytic, Acute, L1 | NA | BeFree | Detail | |
| 0.004 | Leukemia, Myelocytic, Acute | Functional characterization of LiTAPs by interferon-γ ELISPOT (Enzyme-Linked Imm... | BeFree,GAD | 25092142 | Detail |
| <0.001 | myeloid leukemia | NA | BeFree | Detail | |
| 0.006 | Myeloid Leukemia, Chronic | NA | BeFree,GAD | Detail | |
| 0.121 | acute promyelocytic leukemia | NA | BeFree,CTD_human | Detail | |
| <0.001 | Leukemia, T-Cell | NA | BeFree | Detail | |
| 0.121 | Adult T-Cell Lymphoma/Leukemia | NA | BeFree,CTD_human | Detail | |
| <0.001 | Leukoencephalopathy, Progressive Multifocal | NA | BeFree | Detail | |
| <0.001 | lichen disease | NA | BeFree | Detail | |
| <0.001 | lichen planus | NA | BeFree | Detail | |
| <0.001 | Liver Abscess | NA | BeFree | Detail | |
| 0.008 | liver cirrhosis | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Liver Cirrhosis, Alcoholic | NA | BeFree | Detail | |
| 0.120 | Liver Cirrhosis, Experimental | NA | CTD_human | Detail | |
| 0.001 | Liver diseases | NA | BeFree | Detail | |
| 0.005 | Liver neoplasms | NA | BeFree,GAD | Detail | |
| <0.001 | Lown-Ganong-Levine syndrome | NA | BeFree | Detail | |
| 0.003 | Lung diseases | NA | BeFree,GAD | Detail | |
| 0.003 | Chronic Obstructive Airway Disease | In lung CD4+ T cells of most COPD subjects, relative to lung CD4+ T cells in smo... | BeFree,GAD | 24805101 | Detail |
| 0.123 | Lung Neoplasms | We found decreased levels of the transcription factor T-box expressed in T cells... | BeFree,CTD_human,LHGDN | 26348446 | Detail |
| 0.001 | Lupus Vulgaris | NA | BeFree | Detail | |
| 0.002 | Lupus Erythematosus, Discoid | NA | BeFree | Detail | |
| 0.029 | Lupus Erythematosus, Systemic | Furthermore, similarities between disease states in ARE-Del(-/-) mice and SLE pa... | BeFree,GAD,LHGDN | 24583068 | Detail |
| 0.029 | Lupus Erythematosus, Systemic | Aberrant IFN-γ regulation appears to play an important role in anti-CAF-1 antibo... | BeFree,GAD,LHGDN | 24836587 | Detail |
| 0.029 | Lupus Erythematosus, Systemic | Blockade of interferon-γ normalizes interferon-regulated gene expression and ser... | BeFree,GAD,LHGDN | 26138472 | Detail |
| 0.002 | lupus nephritis | NA | BeFree | Detail | |
| <0.001 | Lyme disease | NA | BeFree | Detail | |
| 0.003 | lymphadenitis | NA | BeFree,GAD | Detail | |
| 0.002 | Lymphatic Metastasis | NA | GAD | Detail | |
| <0.001 | lymphocytic choriomeningitis | NA | BeFree | Detail | |
| 0.002 | Lymphocytosis | NA | GAD | Detail | |
| <0.001 | Lymphohistiocytosis, Hemophagocytic | NA | BeFree | Detail | |
| 0.008 | lymphoma | These responses resulted in the generation of IFN-γ-secreting cytotoxic lymphocy... | BeFree,GAD,LHGDN | 25382101 | Detail |
| <0.001 | reticulosarcoma | NA | BeFree | Detail | |
| 0.007 | Lymphoma, Non-Hodgkin | NA | BeFree,GAD | Detail | |
| 0.125 | Lymphoproliferative Disorders | NA | BeFree,CTD_human,GAD | Detail | |
| 0.008 | malaria | This data provides a starting point for functional and genetic analysis of the T... | BeFree,GAD | 25124540 | Detail |
| 0.008 | malaria | Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism hap... | BeFree,GAD | 25445652 | Detail |
| 0.008 | malaria | We observed transcriptional up-regulation in many pathways, including type I int... | BeFree,GAD | 25883389 | Detail |
| 0.002 | Malaria, Cerebral | In this review we consider findings from the clinical disease, in vitro models a... | BeFree | 25177551 | Detail |
| 0.005 | Malaria, Falciparum | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Malaria, Vivax | NA | BeFree | Detail | |
| 0.004 | Malignant neoplasm of stomach | NA | BeFree,GAD | Detail | |
| <0.001 | paroxysmal nocturnal hemoglobinuria | NA | BeFree | Detail | |
| 0.007 | measles | NA | BeFree,LHGDN | Detail | |
| 0.080 | medulloblastoma | NA | BeFree,MGD | Detail | |
| 0.149 | melanoma | Effects of suppressor of cytokine signaling 1 silencing on human melanoma cell p... | BeFree,CTD_human,GAD,LHGDN | 25322862 | Detail |
| 0.149 | melanoma | IFNγ-induced PD-L1 expression in cultured melanomas was assessed in parallel acc... | BeFree,CTD_human,GAD,LHGDN | 25370533 | Detail |
| <0.001 | melioidosis | Transcriptional signatures of both acute and chronic melioidosis revealed upregu... | BeFree | 26311902 | Detail |
| 0.121 | Mesothelioma | NA | BeFree,CTD_human | Detail | |
| 0.001 | mitral valve stenosis | NA | BeFree | Detail | |
| <0.001 | Mixed Salivary Gland Tumor | NA | BeFree | Detail | |
| <0.001 | Mucocutaneous Lymph Node Syndrome | NA | BeFree | Detail | |
| 0.005 | multiple myeloma | NA | BeFree,LHGDN | Detail | |
| 0.002 | Multiple Organ Failure | NA | GAD | Detail | |
| 0.045 | multiple sclerosis | Stimulated PBMC-produced IFN-γ and TNF-α are associated with altered relapse ris... | BeFree,GAD,LHGDN | 24790215 | Detail |
| 0.045 | multiple sclerosis | Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in ... | BeFree,GAD,LHGDN | 25575858 | Detail |
| 0.045 | multiple sclerosis | IL-17-producing CD4(+) T (Th17) cells, along with IFN-γ-expressing Th1 cells, re... | BeFree,GAD,LHGDN | 26223651 | Detail |
| <0.001 | spinal muscular atrophy | NA | BeFree | Detail | |
| <0.001 | myopathy | NA | BeFree | Detail | |
| 0.002 | Musculoskeletal Diseases | NA | GAD | Detail | |
| 0.005 | myasthenia gravis | Several GO terms including the cellular response to interferon-γ, platelet degra... | BeFree,GAD | 25889429 | Detail |
| 0.092 | Mycobacterium Infections | Mendelian susceptibility to mycobacterial disease: genetic, immunological, and c... | BeFree,RGD | 25453225 | Detail |
| 0.092 | Mycobacterium Infections | Human inborn errors of immunity mediated by the cytokines interleukin-17A and in... | BeFree,RGD | 26160376 | Detail |
| 0.003 | Mycoses | Overall, 82.9% of children with Gram-negative bacterial infections were accompan... | BeFree | 25526183 | Detail |
| <0.001 | mycosis fungoides | Of the major polarizing T-cell cytokines, only IFNγ mRNA increases with mycosis ... | BeFree | 24938282 | Detail |
| 0.002 | Myelodysplasia | NA | GAD | Detail | |
| <0.001 | Myeloproliferative disease | Chronically elevated levels of IFN-γ resulted in progressive multiorgan inflamma... | BeFree | 25637019 | Detail |
| 0.010 | myocardial infarction | NA | BeFree,GAD,LHGDN | Detail | |
| 0.004 | myocarditis | We found the induction of myocarditis was associated with the upregulation of Co... | BeFree,LHGDN | 24533969 | Detail |
| <0.001 | myositis | NA | BeFree | Detail | |
| <0.001 | narcolepsy | Patients with narcolepsy were also found to have increased levels of interferon-... | BeFree | 26123389 | Detail |
| <0.001 | Nasal Polyps | NA | BeFree | Detail | |
| 0.002 | Nasopharyngeal Neoplasms | NA | GAD | Detail | |
| 0.120 | Nausea | NA | CTD_human | Detail | |
| 0.120 | Necrosis | NA | CTD_human | Detail | |
| 0.004 | Neoplasm Metastasis | ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish e... | BeFree | 25335731 | Detail |
| 0.004 | Neoplasm Metastasis | IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell grow... | BeFree | 25592039 | Detail |
| 0.004 | Neoplasm Metastasis | We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 l... | BeFree | 25671296 | Detail |
| 0.002 | Neoplasm Recurrence, Local | NA | GAD | Detail | |
| 0.120 | Neoplasms, Experimental | NA | CTD_human | Detail | |
| 0.005 | Pathologic Neovascularization | NA | GAD | Detail | |
| <0.001 | nephroblastoma | NA | BeFree | Detail | |
| 0.120 | Nerve Degeneration | NA | CTD_human | Detail | |
| <0.001 | nervous system disorder | NA | BeFree | Detail | |
| 0.120 | Neural Tube Defects | NA | CTD_human | Detail | |
| <0.001 | neuritis | NA | BeFree | Detail | |
| 0.005 | neuroblastoma | NA | BeFree | Detail | |
| 0.003 | neutropenia | NA | LHGDN | Detail | |
| 0.082 | obesity | These results uncover a dialogue regulated by interactions among T cell IFNγ and... | BeFree,RGD | 25011057 | Detail |
| 0.082 | obesity | We investigated in 102 T2D patients the association of the cytokine polymorphism... | BeFree,RGD | 26064986 | Detail |
| <0.001 | optic neuritis | NA | BeFree | Detail | |
| 0.120 | oral submucous fibrosis | NA | CTD_human | Detail | |
| <0.001 | orbit (eye disorders) | NA | BeFree | Detail | |
| 0.001 | Degenerative polyarthritis | Unbiased analyses by Pathway Studio of the gene sets obtained by discrimination ... | BeFree | 24690414 | Detail |
| 0.003 | osteomyelitis | NA | BeFree,GAD | Detail | |
| <0.001 | osteosarcoma | NA | BeFree | Detail | |
| 0.002 | otitis media | NA | GAD | Detail | |
| 0.004 | ovarian carcinoma | NA | BeFree | Detail | |
| <0.001 | Pain | NA | BeFree | Detail | |
| 0.002 | Pancreatic Neoplasm | NA | GAD | Detail | |
| 0.008 | pancreatitis | Administration of MSCs alone significantly reduced pancreatic injury and inflamm... | BeFree,GAD,LHGDN | 25120736 | Detail |
| 0.001 | pancytopenia | The CART-33 infusion alone induced rigorous chills and fevers; drastic fluctuati... | BeFree | 25174587 | Detail |
| 0.001 | pancytopenia | CD30 as a molecular marker that transiently expresses on IFN-γ-producing T cells... | BeFree | 25383872 | Detail |
| 0.080 | panuveitis | NA | RGD | Detail | |
| <0.001 | papilloma | NA | BeFree | Detail | |
| <0.001 | Parainfluenza | NA | BeFree | Detail | |
| <0.001 | paracoccidioidomycosis | NA | BeFree | Detail | |
| <0.001 | tropical spastic paraparesis | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree | 25833232 | Detail |
| 0.008 | Parkinson disease | NA | GAD,LHGDN | Detail | |
| <0.001 | Pelvic Pain | NA | BeFree | Detail | |
| 0.003 | Pemphigoid, Benign Mucous Membrane | NA | LHGDN | Detail | |
| 0.002 | pemphigus | NA | GAD | Detail | |
| 0.002 | pemphigus vulgaris | NA | GAD | Detail | |
| <0.001 | Peptic Ulcer | NA | BeFree | Detail | |
| <0.001 | periapical granuloma | NA | BeFree | Detail | |
| 0.001 | Periodontal Diseases | Th1-polarized host response, mediated by IFN-γ, has been associated with increas... | BeFree | 25832120 | Detail |
| 0.002 | Periodontal Pocket | NA | GAD | Detail | |
| 0.010 | periodontitis | NA | BeFree,GAD | Detail | |
| 0.003 | Periodontitis, Juvenile | NA | BeFree,GAD | Detail | |
| <0.001 | Peripheral neuropathy | NA | BeFree | Detail | |
| 0.121 | peritonitis | NA | BeFree,CTD_human | Detail | |
| <0.001 | pheochromocytoma | Neuronal pheochromocytoma (PC12) cells induced with amyloid-β peptide 1-42 and i... | BeFree | 25079795 | Detail |
| 0.002 | Picornaviridae Infections | NA | GAD | Detail | |
| <0.001 | Pituitary Diseases | NA | BeFree | Detail | |
| <0.001 | Pituitary Neoplasms | NA | BeFree | Detail | |
| <0.001 | pleurisy | NA | BeFree | Detail | |
| 0.003 | Pneumococcal Infections | NA | BeFree,LHGDN | Detail | |
| 0.122 | pneumonia | The serum concentrations of tumor necrosis factor alpha (median 114.5 pg/ml, ran... | BeFree,CTD_human | 25449230 | Detail |
| 0.006 | polymyalgia rheumatica | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Adenomatous Polyposis Coli | In vitro, IFN-γ administration inhibited Apc-mutated HT-29 colon cancer cell pro... | BeFree | 25383957 | Detail |
| <0.001 | Post-kala-azar dermal leishmaniasis | Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-az... | BeFree | 25466928 | Detail |
| 0.002 | Postoperative Complications | NA | GAD | Detail | |
| 0.007 | pre-eclampsia | NA | GAD,LHGDN | Detail | |
| <0.001 | Pregnancy Complications | Expression of interferon-γ in decidual natural killer cells from women with hype... | BeFree | 24246020 | Detail |
| 0.002 | Pregnancy Complications, Hematologic | NA | GAD | Detail | |
| 0.002 | Pregnancy Complications, Infectious | NA | GAD | Detail | |
| 0.002 | Preleukemia | NA | GAD | Detail | |
| <0.001 | Cardiomyopathies, Primary | NA | BeFree | Detail | |
| 0.006 | Prostatic Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | Protein Deficiency | NA | BeFree | Detail | |
| 0.120 | proteinuria | NA | CTD_human | Detail | |
| 0.011 | psoriasis | NA | BeFree,GAD | Detail | |
| 0.003 | pulmonary emphysema | Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects... | BeFree,GAD | 24805101 | Detail |
| <0.001 | pulmonary fibrosis | NA | BeFree | Detail | |
| 0.002 | purpura | NA | GAD | Detail | |
| 0.005 | Q fever | NA | BeFree,GAD | Detail | |
| <0.001 | Radicular Cyst | NA | BeFree | Detail | |
| <0.001 | kidney failure | NA | BeFree | Detail | |
| 0.082 | Reperfusion Injury | NA | GAD,RGD | Detail | |
| 0.128 | Respiratory Syncytial Virus Infections | IFN-γ CA microsatellite polymorphism is associated with susceptibility to respir... | BeFree,CTD_human,GAD | 25130433 | Detail |
| 0.120 | Respiratory Tract Diseases | NA | BeFree,CTD_human | Detail | |
| 0.002 | Respiratory Tract Infections | NA | GAD | Detail | |
| <0.001 | retinitis pigmentosa | NA | BeFree | Detail | |
| <0.001 | Retroviridae Infections | NA | BeFree | Detail | |
| <0.001 | rhabdomyosarcoma | The miRNA profiles of human rhabdomyosarcoma cells treated with interferon (IFN-... | BeFree | 25287131 | Detail |
| <0.001 | Rheumatism | NA | BeFree | Detail | |
| <0.001 | Rheumatoid Nodule | NA | BeFree | Detail | |
| <0.001 | rubella | NA | BeFree | Detail | |
| 0.003 | Salmonella infections | NA | BeFree,GAD | Detail | |
| 0.120 | Salmonella Infections, Animal | NA | CTD_human | Detail | |
| 0.019 | sarcoidosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | Sarcoidosis, Pulmonary | NA | BeFree,GAD | Detail | |
| <0.001 | Kaposi sarcoma | NA | BeFree | Detail | |
| 0.004 | schistosomiasis | NA | BeFree,LHGDN | Detail | |
| 0.003 | Schistosomiasis japonica | NA | LHGDN | Detail | |
| 0.008 | Schistosomiasis mansoni | NA | BeFree,GAD,LHGDN | Detail | |
| 0.001 | schizophrenia | NA | BeFree | Detail | |
| <0.001 | paranoid schizophrenia | NA | BeFree | Detail | |
| 0.010 | systemic scleroderma | Genotype-mRNA expression correlation analysis revealed that the IRF8 protective ... | BeFree,GAD | 25880423 | Detail |
| <0.001 | scrub typhus | NA | BeFree | Detail | |
| 0.001 | Septicemia | NA | BeFree | Detail | |
| <0.001 | Sezary syndrome | NA | BeFree | Detail | |
| 0.080 | Shock, Hemorrhagic | NA | RGD | Detail | |
| 0.003 | silicosis | NA | BeFree,LHGDN | Detail | |
| 0.004 | Dermatologic disorders | NA | BeFree,GAD | Detail | |
| <0.001 | Skin lesion | NA | BeFree | Detail | |
| <0.001 | Skin Neoplasms | A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/sign... | BeFree | 24464587 | Detail |
| 0.002 | Skin Ulcer | NA | GAD | Detail | |
| <0.001 | smallpox | NA | BeFree | Detail | |
| <0.001 | Soft Tissue Neoplasms | NA | BeFree | Detail | |
| <0.001 | somatostatinoma | NA | BeFree | Detail | |
| <0.001 | Spinal Cord Diseases | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree | 25833232 | Detail |
| <0.001 | Spirochaetales Infections | NA | BeFree | Detail | |
| 0.004 | ankylosing spondylitis | NA | BeFree,LHGDN | Detail | |
| 0.005 | Staphylococcal Infections | NA | GAD,LHGDN | Detail | |
| 0.120 | Stevens-Johnson syndrome | NA | CTD_human | Detail | |
| <0.001 | Stomach Diseases | NA | BeFree | Detail | |
| 0.002 | aphthous stomatitis | NA | GAD | Detail | |
| <0.001 | post-traumatic stress disorder | While the elderly group exhibited robust changes in immune activity such as incr... | BeFree | 24977331 | Detail |
| 0.007 | subacute sclerosing panencephalitis | NA | GAD,LHGDN | Detail | |
| <0.001 | synovitis | NA | BeFree | Detail | |
| 0.009 | Giant Cell Arteritis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.001 | tetanus | NA | BeFree | Detail | |
| 0.002 | Thoracic Neoplasms | NA | GAD | Detail | |
| <0.001 | thromboangiitis obliterans | NA | BeFree | Detail | |
| <0.001 | thymoma | NA | BeFree | Detail | |
| <0.001 | thyroiditis | NA | BeFree | Detail | |
| <0.001 | Tinea | NA | BeFree | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | tonsillitis | Evaluation of IFN-γ polymorphism+874 T/A in patients with recurrent tonsillitis ... | BeFree | 25481866 | Detail |
| 0.001 | toxoplasmosis | NA | BeFree | Detail | |
| 0.005 | Ocular Toxoplasmosis | NA | BeFree,GAD | Detail | |
| <0.001 | trachoma | NA | BeFree | Detail | |
| 0.120 | Infection by Trichuris trichiura | NA | CTD_human | Detail | |
| <0.001 | Trisomy | NA | BeFree | Detail | |
| 0.006 | Chagas disease | These findings point to the crucial role of the IFNγ/STAT1 signal pathway in the... | BeFree,GAD,LHGDN | 25340519 | Detail |
| 0.103 | tuberculosis | Here, we investigated IFN-γ and miR-29a expression dynamics of CD4(+) T cells fr... | BeFree,GAD,LHGDN | 24981709 | Detail |
| 0.103 | tuberculosis | All mice showed strong antibody responses to the InsB protein, and splenocytes s... | BeFree,GAD,LHGDN | 25163841 | Detail |
| 0.103 | tuberculosis | CpG-18 methylation level, TLR2 expressions on monocyte/NK cell, and TNF-α/IFN-γ ... | BeFree,GAD,LHGDN | 25218055 | Detail |
| 0.103 | tuberculosis | Collectively, these data validate p300 as a target of miR-132 and miR-26a, and d... | BeFree,GAD,LHGDN | 25252958 | Detail |
| 0.103 | tuberculosis | The high expressions of TNF-α, IFN-γ in the spinal tuberculous focus were associ... | BeFree,GAD,LHGDN | 25326857 | Detail |
| 0.103 | tuberculosis | Osteopontin (OPN), interferon-γ-induced protein 10 kDa (IP-10), and neutrophil c... | BeFree,GAD,LHGDN | 25378811 | Detail |
| 0.103 | tuberculosis | Diagnostic performance of a cytokine and IFN-γ-induced chemokine mRNA assay afte... | BeFree,GAD,LHGDN | 25528189 | Detail |
| 0.103 | tuberculosis | High concentrations of type I IFNs may block B cell responses or lead to the pro... | BeFree,GAD,LHGDN | 25614319 | Detail |
| 0.103 | tuberculosis | The adaptive immune response in Mycobacterium tuberculosis is predominantly medi... | BeFree,GAD,LHGDN | 25815589 | Detail |
| 0.103 | tuberculosis | Contribution of a heparin-binding haemagglutinin interferon-gamma release assay ... | BeFree,GAD,LHGDN | 25886172 | Detail |
| 0.103 | tuberculosis | There are positive associations between the IFN-γ -874 polymorphism and TB and b... | BeFree,GAD,LHGDN | 25887222 | Detail |
| 0.103 | tuberculosis | High level of IFN-γ released from whole blood of human tuberculosis infections f... | BeFree,GAD,LHGDN | 25959099 | Detail |
| 0.103 | tuberculosis | In conclusion, our results suggest that increased levels of IL-37 in patients wi... | BeFree,GAD,LHGDN | 26073153 | Detail |
| 0.103 | tuberculosis | Here, we show that active human TB infection up-regulates CD244 and CD244 signal... | BeFree,GAD,LHGDN | 26150504 | Detail |
| <0.001 | Tuberculosis, Meningeal | NA | BeFree | Detail | |
| <0.001 | Tuberculosis, Osteoarticular | NA | BeFree | Detail | |
| <0.001 | pleural tuberculosis | NA | BeFree | Detail | |
| 0.031 | Tuberculosis, Pulmonary | Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tubercul... | BeFree,GAD,LHGDN | 24981709 | Detail |
| 0.031 | Tuberculosis, Pulmonary | Association study of polymorphisms in interferon-γ receptor genes with the risk ... | BeFree,GAD,LHGDN | 25815589 | Detail |
| 0.031 | Tuberculosis, Pulmonary | Furthermore, combinations of polymorphisms with IFN-γ -874 were associated with ... | BeFree,GAD,LHGDN | 25887222 | Detail |
| 0.120 | tuberous sclerosis | NA | BeFree,CTD_human | Detail | |
| <0.001 | Unipolar Depression | NA | BeFree | Detail | |
| 0.080 | ureteral obstruction | Here, we tested the hypothesis that cell-specific delivery of IFN-γ to platelet-... | BeFree,RGD | 25466892 | Detail |
| <0.001 | urticaria | NA | BeFree | Detail | |
| 0.006 | uveitis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.005 | Uveomeningoencephalitic Syndrome | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Vascular Diseases | NA | BeFree | Detail | |
| <0.001 | vasculitis | NA | BeFree | Detail | |
| <0.001 | viral hepatitis | NA | BeFree | Detail | |
| 0.003 | Viremia | NA | BeFree,GAD | Detail | |
| 0.005 | Virus Diseases | In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and pro... | BeFree | 25033426 | Detail |
| 0.005 | Virus Diseases | Pretreatment serum interferon gamma inducible protein-10 as biomarker of fibrosi... | BeFree | 25682629 | Detail |
| 0.005 | Virus Diseases | Interferon-γ (IFN-γ) and signal transducers and activators of transcription (STA... | BeFree | 25921106 | Detail |
| 0.003 | vitiligo | NA | BeFree,GAD | Detail | |
| <0.001 | intestinal volvulus | Isolated PBMCs from O. volvulus-infected individuals (164 MF(+) and 46 a-MF) and... | BeFree | 25889652 | Detail |
| 0.120 | Vomiting | NA | CTD_human | Detail | |
| <0.001 | Wheezing | NA | BeFree | Detail | |
| <0.001 | epidermolysis bullosa dystrophica | Plasmatic tumor necrosis factor-β and interferon-γ were higher in DEB patients t... | BeFree | 26496255 | Detail |
| 0.001 | B-Cell Lymphomas | Expanded CD3(+) T-cells with stable and high-level transgene expression (~95%) p... | BeFree | 25427612 | Detail |
| 0.001 | B-Cell Lymphomas | In this study, we show that D393-CD20 is translated in malignant B cells and tha... | BeFree | 25449106 | Detail |
| 0.001 | B-Cell Lymphomas | CD107a degranulation and intracellular IFNγ production were also enhanced in CAR... | BeFree | 25492700 | Detail |
| 0.003 | diffuse large B-cell lymphoma | NA | BeFree,GAD | Detail | |
| <0.001 | Lymphoma, Large-Cell, Follicular | NA | BeFree | Detail | |
| <0.001 | T-Cell Lymphoma | NA | BeFree | Detail | |
| 0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
| <0.001 | Pleural Effusion, Malignant | NA | BeFree | Detail | |
| <0.001 | Fungemia | NA | BeFree | Detail | |
| <0.001 | severe combined immunodeficiency | NA | BeFree | Detail | |
| 0.002 | Bronchial Hyperreactivity | NA | GAD | Detail | |
| <0.001 | eosinophilia-myalgia syndrome | NA | BeFree | Detail | |
| <0.001 | gestational diabetes | NA | BeFree | Detail | |
| 0.002 | erythema infectiosum | NA | GAD | Detail | |
| 0.003 | hepatitis E | NA | BeFree,GAD | Detail | |
| 0.004 | Arthritis, Reactive | NA | BeFree,GAD | Detail | |
| <0.001 | Meningitis, Cryptococcal | NA | BeFree | Detail | |
| 0.120 | Chills | NA | CTD_human | Detail | |
| <0.001 | acute leukemia | NA | BeFree | Detail | |
| <0.001 | Hamman-Rich syndrome | NA | BeFree | Detail | |
| <0.001 | Secondary generalized epilepsy | NA | BeFree | Detail | |
| <0.001 | cataract | NA | BeFree | Detail | |
| <0.001 | Chronic sinusitis | NA | BeFree | Detail | |
| <0.001 | Chronic Persistent Hepatitis | NA | BeFree | Detail | |
| 0.005 | Pancreatitis, Chronic | NA | BeFree,GAD | Detail | |
| 0.003 | Epstein-Barr Virus Infections | NA | BeFree,GAD | Detail | |
| <0.001 | Humoral hypercalcemia of malignancy (disorder) | NA | BeFree | Detail | |
| <0.001 | Small cell carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | obstructive nephropathy | Here, we tested the hypothesis that cell-specific delivery of IFN-γ to platelet-... | BeFree | 25466892 | Detail |
| 0.001 | Active tuberculosis | Whereas M. tuberculosis-specific IFN-γ expression was similar during TB chemothe... | BeFree | 24981709 | Detail |
| 0.009 | Premature Birth | NA | GAD | Detail | |
| <0.001 | renal fibrosis | Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strate... | BeFree | 25466892 | Detail |
| <0.001 | Coronary Occlusion | NA | BeFree | Detail | |
| <0.001 | esophageal carcinoma | NA | BeFree | Detail | |
| 0.002 | retinal vasculitis | NA | GAD | Detail | |
| <0.001 | Joint swelling | NA | BeFree | Detail | |
| <0.001 | Echinococcus granulosus infection | NA | BeFree | Detail | |
| <0.001 | Acute miliary tuberculosis | NA | BeFree | Detail | |
| <0.001 | Non-arthropod borne lymphocytic choriomeningitis | NA | BeFree | Detail | |
| <0.001 | Toxoplasmosis chorioretinitis | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of testis | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of bone | NA | BeFree | Detail | |
| <0.001 | acute myocardial infarction | NA | BeFree | Detail | |
| <0.001 | Inhalational anthrax | NA | BeFree | Detail | |
| 0.003 | allergic asthma | NA | BeFree,GAD | Detail | |
| <0.001 | intrinsic asthma | NA | BeFree | Detail | |
| <0.001 | Intervertebral disc disorder | NA | BeFree | Detail | |
| <0.001 | Cleft palate with cleft lip | Molecular network analysis of these and other cleft lip/palate related module ge... | BeFree | 25579819 | Detail |
| 0.120 | adrenoleukodystrophy | NA | CTD_human | Detail | |
| <0.001 | Liver Failure, Acute | NA | BeFree | Detail | |
| <0.001 | Cicatrix, Hypertrophic | NA | BeFree | Detail | |
| 0.121 | Dermatitis, Allergic Contact | NA | BeFree,CTD_human | Detail | |
| <0.001 | Hypopigmentation disorder | NA | BeFree | Detail | |
| <0.001 | Aortic Aneurysm, Abdominal | NA | BeFree | Detail | |
| <0.001 | Aortic Aneurysm, Thoracic | NA | BeFree | Detail | |
| <0.001 | Autoimmune thyroid disease | NA | BeFree | Detail | |
| 0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | Diabetes, Autoimmune | NA | BeFree | Detail | |
| <0.001 | Pneumonia, Interstitial | NA | BeFree | Detail | |
| 0.003 | Lung Diseases, Interstitial | NA | BeFree,GAD | Detail | |
| 0.003 | Microvascular Angina | NA | BeFree,LHGDN | Detail | |
| <0.001 | Neuroectodermal Tumors | NA | BeFree | Detail | |
| 0.008 | Lichen Planus, Oral | NA | BeFree,GAD | Detail | |
| <0.001 | Ki-1+ Anaplastic Large Cell Lymphoma | NA | BeFree | Detail | |
| <0.001 | hepatoblastoma | NA | BeFree | Detail | |
| 0.003 | angiomyolipoma | NA | BeFree,LHGDN | Detail | |
| 0.006 | Cervical Intraepithelial Neoplasia | IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P <... | BeFree,GAD | 25106529 | Detail |
| 0.006 | Cervical Intraepithelial Neoplasia | To explore the relationship between methylation of interferon gamma (IFN-γ) gene... | BeFree,GAD | 25208560 | Detail |
| 0.002 | Alphavirus Infections | NA | GAD | Detail | |
| <0.001 | Adult Hodgkin Lymphoma | NA | BeFree | Detail | |
| <0.001 | uveal melanoma | NA | BeFree | Detail | |
| 0.002 | Lytic lesion | NA | GAD | Detail | |
| <0.001 | Trichiasis | NA | BeFree | Detail | |
| <0.001 | Lesion of brain | NA | BeFree | Detail | |
| <0.001 | Panarteritis | NA | BeFree | Detail | |
| <0.001 | proliferative glomerulonephritis | NA | BeFree | Detail | |
| 0.003 | pancreatic carcinoma | Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IF... | BeFree | 25725585 | Detail |
| <0.001 | invasive aspergillosis | NA | BeFree | Detail | |
| <0.001 | Colitis, Collagenous | NA | BeFree | Detail | |
| 0.003 | Inclusion Body Myositis (disorder) | NA | LHGDN | Detail | |
| <0.001 | MYOCARDITIS, ACTIVE | NA | BeFree | Detail | |
| <0.001 | Hereditary pancreatitis | NA | BeFree | Detail | |
| <0.001 | bone destruction | To investigate the expression of TNF-α, IFN-γ, TGF-β, and IL-4 in the spinal tub... | BeFree | 25326857 | Detail |
| 0.002 | Fibrosis, Liver | Assess the value of baseline interferon-γ-inducible protein-10 (IP-10) levels as... | BeFree | 25682629 | Detail |
| 0.121 | Hepatitis, Autoimmune | NA | BeFree,CTD_human | Detail | |
| 0.003 | pelvic inflammatory disease | NA | LHGDN | Detail | |
| 0.016 | Malignant neoplasm of lung | NA | BeFree,GAD | Detail | |
| 0.080 | Acute Lung Injury | NA | RGD | Detail | |
| 0.002 | intestinal schistosomiasis | NA | GAD | Detail | |
| 0.003 | Disease Progression | NA | LHGDN | Detail | |
| <0.001 | Parasitemia | NA | BeFree | Detail | |
| <0.001 | Hantavirus Infections | NA | BeFree | Detail | |
| 0.131 | Sepsis | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Carcinoma, Lewis Lung | NA | BeFree | Detail | |
| <0.001 | Psoriasiform eczema | NA | BeFree | Detail | |
| <0.001 | Psoriasis vulgaris | NA | BeFree | Detail | |
| <0.001 | Childhood asthma | NA | BeFree | Detail | |
| 0.004 | Chronic Periodontitis | NA | BeFree,LHGDN | Detail | |
| 0.003 | Vesicular Stomatitis | NA | BeFree,LHGDN | Detail | |
| <0.001 | Typhlocolitis | NA | BeFree | Detail | |
| <0.001 | Acute hepatitis | NA | BeFree | Detail | |
| <0.001 | SLE glomerulonephritis syndrome, WHO class IV | NA | BeFree | Detail | |
| <0.001 | Vulvar Vestibulitis | NA | BeFree | Detail | |
| <0.001 | Atopic cataract | NA | BeFree | Detail | |
| <0.001 | Acute otitis media | NA | BeFree | Detail | |
| 0.002 | Impaired glucose tolerance | NA | BeFree | Detail | |
| <0.001 | Acquired aplastic anemia | NA | BeFree | Detail | |
| <0.001 | Asymptomatic Infections | NA | BeFree | Detail | |
| <0.001 | Coinfection | NA | BeFree | Detail | |
| <0.001 | Primary bacterial peritonitis | NA | BeFree | Detail | |
| 0.003 | Disease due to Parvoviridae | NA | BeFree,GAD | Detail | |
| 0.002 | Respiratory syncytial virus bronchiolitis | NA | GAD | Detail | |
| <0.001 | Acute type B viral hepatitis | NA | BeFree | Detail | |
| <0.001 | Disseminated coccidioidomycosis | NA | BeFree | Detail | |
| <0.001 | Zoonotic form of cutaneous leishmaniasis | NA | BeFree | Detail | |
| <0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
| <0.001 | Ovarian epithelial cancer recurrent | NA | BeFree | Detail | |
| <0.001 | DS Stage I Plasma Cell Myeloma | NA | BeFree | Detail | |
| <0.001 | stage III melanoma | NA | BeFree | Detail | |
| 0.002 | Metastatic melanoma | Adoptive T cell therapy combined with intralesional administrations of TG1042 (a... | BeFree | 25846669 | Detail |
| <0.001 | Melanoma recurrent | In the present study we reveal a combination of IFN-γ-irreversible structural an... | BeFree | 26381407 | Detail |
| <0.001 | Cancer of Head and Neck | NA | BeFree | Detail | |
| 0.001 | Squamous cell carcinoma of esophagus | Furthermore, CALR/MAGE-A3-infected DCs stimulated CD8(+) cytotoxic T lymphocytes... | BeFree | 25863743 | Detail |
| <0.001 | Transitional cell carcinoma of bladder | NA | BeFree | Detail | |
| 0.001 | Solid tumour | NA | BeFree | Detail | |
| <0.001 | stage, neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Vascular Neoplasms | NA | BeFree | Detail | |
| <0.001 | Disease caused by Shigella dysenteriae | NA | BeFree | Detail | |
| 0.016 | cervix carcinoma | IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P <... | BeFree,GAD | 25106529 | Detail |
| 0.016 | cervix carcinoma | Methylation patterns of the IFN-γ gene in cervical cancer tissues. | BeFree,GAD | 25208560 | Detail |
| 0.016 | cervix carcinoma | B7-H4 is overexpressed in human cervical cancers, and it is associated with lowe... | BeFree,GAD | 25446402 | Detail |
| 0.016 | cervix carcinoma | Interferon gamma +874 T/A polymorphism increases the risk of cervical cancer: ev... | BeFree,GAD | 25649976 | Detail |
| 0.016 | cervix carcinoma | Association Study of Single-Nucleotide Polymorphisms of STAT2/STAT3/IFN-γ Genes ... | BeFree,GAD | 25921106 | Detail |
| <0.001 | Air cyst | NA | BeFree | Detail | |
| <0.001 | Restenosis | NA | BeFree | Detail | |
| <0.001 | Senile Plaques | NA | BeFree | Detail | |
| <0.001 | Tumor necrosis | NA | BeFree | Detail | |
| 0.003 | Atrophic | NA | LHGDN | Detail | |
| <0.001 | Lymphoid hyperplasia | NA | BeFree | Detail | |
| <0.001 | histiocytic sarcoma | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of colon | NA | BeFree | Detail | |
| <0.001 | Impaired cognition | NA | BeFree | Detail | |
| 0.006 | Thyroid associated opthalmopathies | NA | BeFree,GAD | Detail | |
| <0.001 | Pleural plaque | NA | BeFree | Detail | |
| <0.001 | Stable angina | Furthermore, MDSCs from ACS patients were more potent suppressors of T-cell prol... | BeFree | 25591771 | Detail |
| <0.001 | Hyperplastic lymph node | NA | BeFree | Detail | |
| <0.001 | eosinophilic esophagitis | NA | BeFree | Detail | |
| <0.001 | Chronic liver disease | NA | BeFree | Detail | |
| 0.002 | Complications of Diabetes Mellitus | NA | GAD | Detail | |
| <0.001 | Erythema nodosum leprosum | Interferon γ was identified as a significant upstream regulator of the expressio... | BeFree | 25398459 | Detail |
| <0.001 | Chronic Chagas' disease | NA | BeFree | Detail | |
| <0.001 | Hepatosplenic schistosomiasis | NA | BeFree | Detail | |
| <0.001 | Leprosy, Multibacillary | However, we found that variants rs692527 (P = 0.022) and rs34856358 (P = 0.022) ... | BeFree | 22392581 | Detail |
| 0.002 | Malignant neoplasm of liver | NA | GAD | Detail | |
| <0.001 | malignant mesothelioma | NA | BeFree | Detail | |
| 0.005 | Malignant neoplasm of pancreas | Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IF... | BeFree,GAD | 25725585 | Detail |
| 0.120 | Aplastic anemia, idiopathic | Immune abnormalities such as decreased lymphocyte counts, inverted CD4/CD8 T-cel... | BeFree,ORPHANET | 25383872 | Detail |
| <0.001 | Cervical intraepithelial neoplasia grade 1 | The methylation rates of the IFN-γ gene were significantly higher in cervical ca... | BeFree | 25208560 | Detail |
| <0.001 | Cervical intraepithelial neoplasia grade 2 | Likewise, the IFN-γ expression levels in CIN II/III tissues with methylation (0.... | BeFree | 25208560 | Detail |
| <0.001 | Squamous cell carcinoma of tongue | NA | BeFree | Detail | |
| <0.001 | prediabetes syndrome | NA | BeFree | Detail | |
| 0.003 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with th... | BeFree | 24448078 | Detail |
| 0.003 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | Gastric infections led by Hp induce a Th-1 cellular immune response, regulated m... | BeFree | 24754375 | Detail |
| 0.003 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | Helicobacter pylori Outer Membrane Protein 18 (Hp1125) Is Involved in Persistent... | BeFree | 25945338 | Detail |
| 0.004 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total c... | BeFree | 24655063 | Detail |
| 0.004 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | IFN-γ CA microsatellite polymorphism was associated with the susceptibility of C... | BeFree | 25130433 | Detail |
| 0.004 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | Together, the results of this study identify environmental and genetic factors t... | BeFree | 25555213 | Detail |
| 0.001 | Malignant neoplasm of prostate | EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeu... | BeFree | 24953652 | Detail |
| 0.002 | Hematologic Neoplasms | NA | GAD | Detail | |
| 0.002 | Endotoxemia | NA | GAD | Detail | |
| 0.005 | Atopy | NA | GAD | Detail | |
| 0.003 | Immune thrombocytopenic purpura | NA | BeFree,GAD | Detail | |
| <0.001 | Hereditary gingival fibromatosis | NA | BeFree | Detail | |
| <0.001 | Early onset periodontitis | NA | BeFree | Detail | |
| <0.001 | Acute hepatitis C | NA | BeFree | Detail | |
| <0.001 | Non-alcoholic Fatty Liver Disease | In addition, decreased numbers of CD4+ and CD8+ T lymphocytes and increased leve... | BeFree | 25644696 | Detail |
| <0.001 | Steroid-sensitive nephrotic syndrome | NA | BeFree | Detail | |
| <0.001 | Steroid-resistant nephrotic syndrome | NA | BeFree | Detail | |
| <0.001 | Idiopathic crescentic glomerulonephritis | Kidneys with crescentic GN contained CD4(+) cells responding to α3IV-NC1 with th... | BeFree | 25965582 | Detail |
| <0.001 | Chronic rejection of renal transplant | NA | BeFree | Detail | |
| <0.001 | Eosinophilic pustular folliculitis | NA | BeFree | Detail | |
| 0.001 | lupus erythematosus | NA | BeFree | Detail | |
| <0.001 | Human anaplasmosis due to Anaplasma phagocytophilum | NA | BeFree | Detail | |
| <0.001 | combined immunodeficiency | NA | BeFree | Detail | |
| <0.001 | Pleurisy with pleural effusion | NA | BeFree | Detail | |
| <0.001 | Chlamydia trachomatis infection | NA | BeFree | Detail | |
| <0.001 | Chronic active hepatitis | NA | BeFree | Detail | |
| <0.001 | Bilateral cataracts (disorder) | NA | BeFree | Detail | |
| <0.001 | Associated symptom | NA | BeFree | Detail | |
| <0.001 | Metabolic syndrome X | NA | BeFree | Detail | |
| 0.011 | Hepatitis B, Chronic | NA | BeFree,GAD | Detail | |
| 0.018 | Hepatitis C, Chronic | Serum IFN-γ levels were significantly reduced in EBV/HCV patients (3.86 pg/mL) c... | BeFree,GAD,LHGDN | 25317700 | Detail |
| 0.002 | Mood Disorders | NA | GAD | Detail | |
| <0.001 | Mixed cryoglobulinemia | NA | BeFree | Detail | |
| 0.008 | Malignant neoplasm of esophagus | NA | BeFree,GAD | Detail | |
| <0.001 | X-Linked Lymphoproliferative Disorder | NA | BeFree | Detail | |
| <0.001 | Malignant glioma | NA | BeFree | Detail | |
| <0.001 | Oral infection | NA | BeFree | Detail | |
| <0.001 | Malignant melanoma of eye | NA | BeFree | Detail | |
| <0.001 | Drug-induced erythema multiforme | NA | BeFree | Detail | |
| <0.001 | Chronic idiopathic urticaria | Role of IFN-γ and IL-6 cytokines and their association in determining susceptibi... | BeFree | 25409241 | Detail |
| <0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
| <0.001 | Varicella-zoster virus infection | NA | BeFree | Detail | |
| <0.001 | Aqueous Humor Disorders | NA | BeFree | Detail | |
| 0.001 | Carcinogenesis | The hypermethylation of IFN-γ gene may be related with tumorigenesis of cervical... | BeFree | 25208560 | Detail |
| 0.001 | Carcinogenesis | Interferon-γ (IFN-γ) and signal transducers and activators of transcription (STA... | BeFree | 25921106 | Detail |
| 0.002 | prostate carcinoma | EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeu... | BeFree | 24953652 | Detail |
| 0.120 | Manganese Poisoning | NA | CTD_human | Detail | |
| 0.007 | Hashimoto Disease | NA | BeFree,GAD,LHGDN | Detail | |
| 0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| <0.001 | Progressive Neoplastic Disease | NA | BeFree | Detail | |
| 0.008 | breast carcinoma | ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish e... | BeFree | 25335731 | Detail |
| <0.001 | Tuberculosis, extrapulmonary | NA | BeFree | Detail | |
| 0.002 | Carcinoma of lung | NA | BeFree | Detail | |
| 0.002 | Pregnancy loss | NA | GAD | Detail | |
| 0.004 | colon carcinoma | NA | BeFree | Detail | |
| 0.002 | stomach carcinoma | It suggested that the Runx3 and Th1-associated factors including T-bet and IFN-γ... | BeFree | 25270738 | Detail |
| 0.002 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | airway disease | NA | BeFree | Detail | |
| 0.005 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Dissecting aneurysm of the thoracic aorta | NA | BeFree | Detail | |
| <0.001 | Viral respiratory infection | NA | BeFree | Detail | |
| <0.001 | Genital infection | NA | BeFree | Detail | |
| <0.001 | Corneal infection | NA | BeFree | Detail | |
| <0.001 | Granulomatous disorder | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of kidney | NA | BeFree,GAD | Detail | |
| <0.001 | Acute pneumonia | NA | BeFree | Detail | |
| <0.001 | allergic symptom | NA | BeFree | Detail | |
| <0.001 | Hypereosinophilia | NA | BeFree | Detail | |
| <0.001 | Periodontal infection | Th1-polarized host response, mediated by IFN-γ, has been associated with increas... | BeFree | 25832120 | Detail |
| <0.001 | early pregnancy | NA | BeFree | Detail | |
| 0.003 | Idiopathic Inflammatory Myopathies | NA | BeFree,GAD | Detail | |
| <0.001 | Carotid Artery Plaque | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree | 25196434 | Detail |
| <0.001 | Multiple Sclerosis, Secondary Progressive | NA | BeFree | Detail | |
| <0.001 | nasal allergy | NA | BeFree | Detail | |
| <0.001 | Spots on skin | NA | BeFree | Detail | |
| <0.001 | Subfertility, Male | NA | BeFree | Detail | |
| 0.004 | Helicobacter pylori infection | NA | BeFree,GAD | Detail | |
| <0.001 | Pelvic pain female | NA | BeFree | Detail | |
| <0.001 | Immunodeficiency congenital | NA | BeFree | Detail | |
| <0.001 | Oestrogen deficiency | NA | BeFree | Detail | |
| <0.001 | Chronic proliferative glomerulonephritis | NA | BeFree | Detail | |
| 0.002 | Acute GVH disease | Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD c... | BeFree | 25774595 | Detail |
| <0.001 | Persistant generalized lymphadenopathy | NA | BeFree | Detail | |
| 0.003 | Thrombocytopenic purpura | NA | LHGDN | Detail | |
| <0.001 | Acute schizophrenia | NA | BeFree | Detail | |
| 0.120 | Drug-Induced Liver Injury | NA | CTD_human | Detail | |
| 0.001 | Chronic graft-versus-host disease | NA | BeFree | Detail | |
| <0.001 | latent infection | NA | BeFree | Detail | |
| <0.001 | Histiocytosis haematophagic | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathies | NA | BeFree | Detail | |
| <0.001 | Diffuse panbronchiolitis | NA | BeFree | Detail | |
| 0.003 | ovarian neoplasm | NA | BeFree,LHGDN | Detail | |
| 0.001 | autoimmune thyroiditis | NA | BeFree | Detail | |
| <0.001 | eczema herpeticum | NA | BeFree | Detail | |
| 0.003 | Acute coronary syndrome | NA | BeFree,GAD | Detail | |
| <0.001 | Spondylarthritis | NA | BeFree | Detail | |
| 0.002 | Spondylarthropathies | NA | GAD | Detail | |
| 0.002 | Papillomavirus Infections | NA | GAD | Detail | |
| 0.001 | Arthritis, Collagen-Induced | NA | BeFree | Detail | |
| 0.200 | Arthritis, Experimental | NA | CTD_human,RGD | Detail | |
| <0.001 | Chlamydia pneumoniae infection | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
| <0.001 | endometrial adenocarcinoma | NA | BeFree | Detail | |
| 0.010 | severe acute respiratory syndrome | NA | BeFree,GAD,LHGDN | Detail | |
| 0.120 | sarcoma | NA | BeFree,CTD_human | Detail | |
| <0.001 | Fungal keratitis | NA | BeFree | Detail | |
| <0.001 | Persistent infection | Significantly, AA homozygous genotype was dominant in chronic hepatitis B cases ... | BeFree | 24446686 | Detail |
| <0.001 | Fatal infectious mononucleosis | NA | BeFree | Detail | |
| <0.001 | major depressive disorder | NA | BeFree | Detail | |
| <0.001 | Cutaneous lymphoma | NA | BeFree | Detail | |
| <0.001 | Inflammatory disorder | Genetic variations in TGF-β and IFN-γ may interfere with proinflammatory cytokin... | BeFree | 25147823 | Detail |
| <0.001 | Inflammatory disorder | Following disease induction, daily systemic administration of human recombinant ... | BeFree | 25619792 | Detail |
| <0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
| <0.001 | Aggressive natural killer-cell leukemia | NA | BeFree | Detail | |
| <0.001 | Generalized vitiligo | NA | BeFree | Detail | |
| <0.001 | ACTH-secreting pituitary adenoma | NA | BeFree | Detail | |
| <0.001 | Eosinophilic disorder | Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total c... | BeFree | 24655063 | Detail |
| <0.001 | Stromal keratitis | The reduced SK lesion severity was reflected by increased phosphatidylinositol-3... | BeFree | 25700796 | Detail |
| <0.001 | Liver regeneration disorder | NA | BeFree | Detail | |
| 0.120 | mucocutaneous leishmaniasis | NA | CTD_human | Detail | |
| <0.001 | Autologous graft versus host disease | NA | BeFree | Detail | |
| <0.001 | childhood leukemia | NA | BeFree | Detail | |
| <0.001 | Classical Hodgkin's Lymphoma | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Visual Manifestations | NA | BeFree | Detail | |
| <0.001 | pancreatic somatostatinoma | NA | BeFree | Detail | |
| <0.001 | Mixed Neoplasm | NA | BeFree | Detail | |
| 0.001 | renal carcinoma | NA | BeFree | Detail | |
| <0.001 | Systemic onset juvenile chronic arthritis | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathy, Familial Idiopathic | NA | BeFree | Detail | |
| 0.130 | Mammary Neoplasms | NA | BeFree,CTD_human,LHGDN | Detail | |
| <0.001 | Desmoplastic | NA | BeFree | Detail | |
| <0.001 | Salivary Gland Pleomorphic Adenoma | NA | BeFree | Detail | |
| <0.001 | Tumor Immunity | NA | BeFree | Detail | |
| 0.003 | colorectal cancer | A subset of colorectal cancer displayed high infiltration with activated CD8(+) ... | BeFree | 25358689 | Detail |
| 0.003 | colorectal cancer | Deficiency of interferon-gamma or its receptor promotes colorectal cancer develo... | BeFree | 25383957 | Detail |
| 0.003 | colorectal cancer | A positive feedback loop between IRF1 and miR-29b may contribute to the sensitiv... | BeFree | 25592039 | Detail |
| 0.003 | colorectal cancer | We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 l... | BeFree | 25671296 | Detail |
| 0.003 | colorectal cancer | Our results demonstrate that ATG5 plays important roles in intestinal tumor grow... | BeFree | 25695667 | Detail |
| 0.005 | Sjogren's syndrome | NA | GAD | Detail | |
| 0.120 | APLASTIC ANEMIA, SUSCEPTIBILITY TO (finding) | NA | CLINVAR | Detail | |
| 0.120 | Tsc2 Angiomyolipomas, Renal, Modifier Of | NA | CLINVAR | Detail | |
| <0.001 | Non-Malignant Ascites Adverse Event | NA | BeFree | Detail | |
| <0.001 | Leprosy, Multibacillary | NA | BeFree | Detail | |
| 0.122 | Renal Insufficiency | NA | CTD_human,GAD | Detail | |
| 0.002 | Latent Tuberculosis | NA | BeFree | Detail | |
| <0.001 | Immune Reconstitution Inflammatory Syndrome | NA | BeFree | Detail | |
| <0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
| <0.001 | Cirrhosis | NA | BeFree | Detail | |
| <0.001 | Disorder characterized by eosinophilia | Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total c... | BeFree | 24655063 | Detail |
| <0.001 | Benign Prostatic Hyperplasia | NA | BeFree | Detail | |
| <0.001 | Heymann Nephritis | NA | BeFree | Detail | |
| <0.001 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
| 0.001 | Idiopathic Pulmonary Fibrosis | NA | BeFree | Detail | |
| <0.001 | Chromosome 11p11.2 Deletion Syndrome | NA | BeFree | Detail | |
| 0.120 | MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) | NA | CTD_human | Detail | |
| <0.001 | IMMUNE SUPPRESSION | The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated ... | BeFree | 25449949 | Detail |
| <0.001 | Recurrent infections (sinusitis and bacterial pneumonia and meningitis) | NA | BeFree | Detail | |
| <0.001 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | NA | BeFree | Detail | |
| <0.001 | peeling skin syndrome | NA | BeFree | Detail | |
| <0.001 | Myeloproliferative disorder, chronic, with eosinophilia | IL-35, IL-17 and IFN-γ were elevated in TPE compared with MPE (all P<0.01). | BeFree | 25935866 | Detail |
| <0.001 | lateral meningocele syndrome | NA | BeFree | Detail | |
| 0.103 | tuberculosis | Concerning the key role of interferon-γ (IFN-γ) in the protective immunity again... | BeFree | 21470497 | Detail |
| 0.120 | TUBEROUS SCLEROSIS 1 (disorder) | NA | CTD_human | Detail | |
| 0.120 | TUBEROUS SCLEROSIS 2 (disorder) | NA | CTD_human | Detail | |
| 0.003 | coronary artery disease | NA | BeFree,GAD | Detail | |
| <0.001 | Parvovirus B19 (disease) | NA | BeFree | Detail | |
| <0.001 | Latent autoimmune diabetes mellitus in adult | NA | BeFree | Detail | |
| <0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
| <0.001 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree | Detail | |
| 0.080 | MALARIA, SUSCEPTIBILITY TO (finding) | NA | MGD | Detail | |
| 0.015 | liver carcinoma | A SNP-SNP interaction between IL-2-330 and IFN-γ-1615 was associated with an inc... | BeFree,GAD,LHGDN | 25169554 | Detail |
| 0.015 | liver carcinoma | Interferon-γ +874A/T polymorphism and hepatocellular carcinoma risk: a meta-anal... | BeFree,GAD,LHGDN | 25739411 | Detail |
| <0.001 | Cryopyrin-Associated Periodic Syndromes | NA | BeFree | Detail | |
| <0.001 | Chronic kidney disease stage 5 | NA | BeFree | Detail | |
| <0.001 | ISS Stage I Plasma Cell Myeloma | NA | BeFree | Detail | |
| <0.001 | Idiopathic Interstitial Pneumonias | NA | BeFree | Detail | |
| <0.001 | Pulmonary Aspergillosis | NA | BeFree | Detail | |
| <0.001 | Bronchopulmonary Aspergillosis | NA | BeFree | Detail | |
| 0.003 | Allergic rhinitis (disorder) | NA | BeFree,GAD | Detail | |
| 0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
| 0.002 | Recurrent pregnancy loss | NA | GAD | Detail | |
| <0.001 | Bone Marrow failure syndromes | NA | BeFree | Detail | |
| 0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
| <0.001 | Plaque, Amyloid | NA | BeFree | Detail | |
| <0.001 | Disturbance in mood | NA | BeFree | Detail | |
| 0.002 | Deficiency of glucose-6-phosphate dehydrogenase | NA | GAD | Detail | |
| <0.001 | Tuberculous pleural effusion | ELISPOT assay showed that IL-35 reduced the proportion of IFN-γ-producing CD4+ T... | BeFree | 25935866 | Detail |
| <0.001 | MASP2 Deficiency | NA | BeFree | Detail | |
| <0.001 | Nonalcoholic Steatohepatitis | NA | BeFree | Detail | |
| 0.002 | myelodysplastic syndrome | NA | GAD | Detail | |
| 0.002 | FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | NA | BeFree | Detail | |
| <0.001 | American cutaneous leishmaniasis | NA | BeFree | Detail | |
| 0.008 | Juvenile arthritis | NA | BeFree,GAD | Detail | |
| 0.002 | granulomatosis with polyangiitis | NA | GAD | Detail | |
| <0.001 | Progressive cGVHD | NA | BeFree | Detail | |
| 0.001 | Allergic disposition | However, microbe-related protection from allergy seems to mainly depend on epige... | BeFree | 24925396 | Detail |
| <0.001 | Intracranial glioma | NA | BeFree | Detail | |
| <0.001 | Neutrophilia (disorder) | NA | BeFree | Detail | |
| 0.073 | Infection | NA | GAD,LHGDN | Detail | |
| <0.001 | Pneumonitis | The serum concentrations of tumor necrosis factor alpha (median 114.5 pg/ml, ran... | BeFree | 25449230 | Detail |
| 0.001 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
| <0.001 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
| <0.001 | Chronic idiopathic pulmonary fibrosis | NA | BeFree | Detail | |
| <0.001 | Chlamydophila pneumoniae infections | NA | BeFree | Detail | |
| <0.001 | Disseminated Bacillus Calmette-Guerin Infection | NA | BeFree | Detail | |
| <0.001 | Acute-On-Chronic Liver Failure | NA | BeFree | Detail | |
| 0.120 | Job Syndrome | NA | CTD_human | Detail | |
| 0.002 | Spontaneous abortion | NA | GAD | Detail | |
| <0.001 | Abscess | NA | BeFree | Detail | |
| 0.122 | acquired immunodeficiency syndrome | NA | CTD_human,GAD | Detail | |
| <0.001 | Acute alcoholic liver disease | Fewer T cells from patients with AAH produced interferon gamma in response to li... | BeFree | 25479137 | Detail |
| 0.006 | adenocarcinoma | The Apc(Min/+)IFN-γ(+/-) mice presented with increased number and size of adenom... | BeFree,GAD,LHGDN | 25383957 | Detail |
| 0.007 | measles | A significant association was found between lower measles-specific IFN-γ Enzyme-... | BeFree | 22082653 | Detail |
| <0.001 | adenoma | Molecular analyses of the adenomas suggested that heterozygous deletion of IFN-γ... | BeFree | 25383957 | Detail |
| <0.001 | adenoma | Heterozygous deletion of ATG5 in Apc(Min/+) mice promotes intestinal adenoma gro... | BeFree | 25695667 | Detail |
| <0.001 | Adenovirus Infections | NA | BeFree | Detail | |
| 0.003 | alopecia areata | NA | LHGDN | Detail | |
| 0.003 | Alveolar Bone Loss | NA | LHGDN | Detail | |
| <0.001 | extrinsic allergic alveolitis | NA | BeFree | Detail | |
| 0.008 | Alzheimer's disease | NA | BeFree,GAD | Detail | |
| <0.001 | amyotrophic lateral sclerosis | NA | BeFree | Detail | |
| 0.003 | anemia | NA | BeFree,LHGDN | Detail | |
| 0.133 | aplastic anemia | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Cooley's anemia | NA | BeFree | Detail | |
| 0.003 | Anemia, Sickle Cell | NA | BeFree,GAD | Detail | |
| <0.001 | Aneurysm | NA | BeFree | Detail | |
| 0.002 | Angina Pectoris | NA | GAD | Detail | |
| 0.001 | Angina, Unstable | The upregulation of miR-155 expression was positively correlated with the percen... | BeFree | 25760478 | Detail |
| <0.001 | anhidrosis | NA | BeFree | Detail | |
| 0.003 | anorexia nervosa | NA | BeFree,LHGDN | Detail | |
| 0.003 | Anoxia | NA | LHGDN | Detail | |
| <0.001 | aortic aneurysm | NA | BeFree | Detail | |
| 0.120 | appendicitis | NA | CTD_human | Detail | |
| 0.011 | arteriosclerosis | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree,LHGDN | 25196434 | Detail |
| 0.011 | arteriosclerosis | STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells refle... | BeFree,LHGDN | 25478796 | Detail |
| 0.011 | arteriosclerosis | Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... | BeFree,LHGDN | 25740578 | Detail |
| 0.018 | arthritis | Relationship of CD146 expression to secretion of interleukin (IL)-17, IL-22 and ... | BeFree,GAD,LHGDN | 25113810 | Detail |
| 0.018 | arthritis | These data demonstrate that the molecular pathways IL-23/17 and IL-12/IFN-γ may ... | BeFree,GAD,LHGDN | 25253467 | Detail |
| 0.018 | arthritis | In this issue of the European Journal of Immunology [Eur.J. Immunol.2015.45: 988... | BeFree,GAD,LHGDN | 25727209 | Detail |
| 0.120 | Arthritis, Infectious | NA | CTD_human | Detail | |
| <0.001 | Arthritis, Psoriatic | NA | BeFree | Detail | |
| 0.147 | rheumatoid arthritis | Unbiased analyses by Pathway Studio of the gene sets obtained by discrimination ... | BeFree,CTD_human,GAD,LHGDN | 24690414 | Detail |
| 0.147 | rheumatoid arthritis | Expression of Interferon-γ Receptor Genes in Peripheral Blood Mononuclear Cells ... | BeFree,CTD_human,GAD,LHGDN | 25708927 | Detail |
| 0.147 | rheumatoid arthritis | After 24weeks of treatment, percentages of IFNγ-induced pSTAT1+ and IL-10-induce... | BeFree,CTD_human,GAD,LHGDN | 25847223 | Detail |
| <0.001 | aspergillosis | NA | BeFree | Detail | |
| <0.001 | Aspergillosis, Allergic Bronchopulmonary | These data provide a rationale to explore IFNγ therapy in ABPA as a corticostero... | BeFree | 24912986 | Detail |
| 0.043 | asthma | It is crucial for naive T lymphocyte development, interferon-γ production, airwa... | BeFree,GAD,LHGDN | 25056814 | Detail |
| 0.043 | asthma | Association between FcεRIβ and IFN-γ Polymorphisms and Asthma in Asian Populatio... | BeFree,GAD,LHGDN | 25530133 | Detail |
| 0.043 | asthma | Healthy and asthmatic ASM cells were treated with TNF-α/IFN-γ for 24 hours in th... | BeFree,GAD,LHGDN | 25897650 | Detail |
| 0.043 | asthma | High IFN-γ and low SLPI mark severe asthma in mice and humans. | BeFree,GAD,LHGDN | 26121748 | Detail |
| 0.003 | Astrocytoma | NA | BeFree | Detail | |
| <0.001 | Ataxia | NA | BeFree | Detail | |
| 0.130 | atherosclerosis | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree,CTD_human,GAD | 25196434 | Detail |
| 0.130 | atherosclerosis | STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells refle... | BeFree,CTD_human,GAD | 25478796 | Detail |
| 0.130 | atherosclerosis | Atorvastatin treatment increased the percentage and inhibitory ability of nTregs... | BeFree,CTD_human,GAD | 25740578 | Detail |
| 0.120 | autistic disorder | NA | CTD_human | Detail | |
| 0.131 | Autoimmune Diseases | Type 1 Diabetes (T1D) is an autoimmune disease where local release of cytokines ... | BeFree,CTD_human,GAD | 24462878 | Detail |
| 0.131 | Autoimmune Diseases | Pathogenic functions of B cells in autoimmune diseases: IFN-γ production joins t... | BeFree,CTD_human,GAD | 25727209 | Detail |
| <0.001 | Melanoma, B16 | NA | BeFree | Detail | |
| 0.004 | Bacterial Infections | These immunized mice had significantly higher levels of IgG1 and IgG2a to rOmpB-... | BeFree,GAD | 25909586 | Detail |
| 0.009 | Behcet Syndrome | Th17 cells, mainly producing the cytokine IL-17, and Th1 cells, characterized by... | BeFree,GAD,LHGDN | 25056541 | Detail |
| 0.001 | biliary atresia | NA | BeFree | Detail | |
| 0.009 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
| <0.001 | Bladder Neoplasm | NA | BeFree | Detail | |
| <0.001 | Bone Marrow Diseases | High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-... | BeFree | 25833232 | Detail |
| <0.001 | borderline personality disorder | NA | BeFree | Detail | |
| 0.005 | boutonneuse fever | NA | GAD,LHGDN | Detail | |
| 0.120 | Brain Diseases | NA | CTD_human | Detail | |
| <0.001 | Brain Neoplasms | NA | BeFree | Detail | |
| 0.019 | Malignant neoplasm of breast | ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish e... | BeFree,GAD | 25335731 | Detail |
| 0.002 | bronchiectasis | NA | GAD | Detail | |
| 0.003 | bronchiolitis | IFN-γ, an essential cytokine in the viral cell-mediated immune response, has bee... | BeFree,GAD | 25130433 | Detail |
| 0.123 | bronchiolitis obliterans | NA | BeFree,CTD_human,LHGDN | Detail | |
| 0.005 | Bronchiolitis, Viral | NA | GAD | Detail | |
| <0.001 | bronchopulmonary dysplasia | NA | BeFree | Detail | |
| 0.019 | brucellosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Cachexia | NA | GAD | Detail | |
| 0.002 | Campylobacter infection | NA | GAD | Detail | |
| 0.003 | Candidiasis, Chronic Mucocutaneous | NA | BeFree,LHGDN | Detail | |
| 0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| 0.002 | Non-small cell lung carcinoma | We found decreased levels of the transcription factor T-box expressed in T cells... | BeFree | 26348446 | Detail |
| 0.004 | renal cell carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic ex... | DisGeNET | Detail |
| The aims of this study were to ascertain whether five SNPs in the TNFA promoter (-1031T>C,-857C>T,-3... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P < 0.05). | DisGeNET | Detail |
| Methylation patterns of the IFN-γ gene in cervical cancer tissues. | DisGeNET | Detail |
| B7-H4 is overexpressed in human cervical cancers, and it is associated with lower numbers of tumor-i... | DisGeNET | Detail |
| Interferon gamma +874 T/A polymorphism increases the risk of cervical cancer: evidence from a meta-a... | DisGeNET | Detail |
| Association Study of Single-Nucleotide Polymorphisms of STAT2/STAT3/IFN-γ Genes in Cervical Cancer i... | DisGeNET | Detail |
| Furthermore, the mRNA expression of IFN-γ in cervical tumors with methylation (0.71 ± 0.13, n = 8) w... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we show that the NF-κB protein c-Rel regulates the inflammatory potential of colonic IFN-γ(+)T... | DisGeNET | Detail |
| SEW2871 treatment attenuated established colitis associated with decreased CD4+ T cells in colon lam... | DisGeNET | Detail |
| In addition, IL-10 KO mice receiving Bifico treatment had reduced mucosal secretion of tumor necrosi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A subset of colorectal cancer displayed high infiltration with activated CD8(+) cytotoxic T lymphocy... | DisGeNET | Detail |
| Deficiency of interferon-gamma or its receptor promotes colorectal cancer development. | DisGeNET | Detail |
| A positive feedback loop between IRF1 and miR-29b may contribute to the sensitivity of CRC cells to ... | DisGeNET | Detail |
| We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 ligand) and infiltrat... | DisGeNET | Detail |
| Our results demonstrate that ATG5 plays important roles in intestinal tumor growth and combination o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our data demonstrate a pronounced reduction of HLA-DQ expression in CF, which is associated with inf... | DisGeNET | Detail |
| Interferon-gamma gene polymorphism +874 A/T is associated with an increased risk of cytomegalovirus ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| However, while DENV-NS3 specific T cells of those with mild/sub clinical dengue infection were more ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Type 1 Diabetes (T1D) is an autoimmune disease where local release of cytokines such as IL-1β and IF... | DisGeNET | Detail |
| The results revealed that the DM1-preventing function was in part caused by a reduction in the pro-i... | DisGeNET | Detail |
| T cells secreting the cytokines IFN-γ and IL-10 in response to seven peptides known to elicit T cell... | DisGeNET | Detail |
| We investigated in 102 T2D patients the association of the cytokine polymorphisms in the TNF-α, IL-1... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Importantly, high IL-7 expression was detected in the CNS during EAE and could drive the plasticity ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total cell counts and eosin... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Pro-inflammatory and antiviral cytokines (granulocyte macrophage colony stimulating factor, interfer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Th1-polarized host response, mediated by IFN-γ, has been associated with increased severity of perio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD can discriminate pati... | DisGeNET | Detail |
| Alloantigen-induced IL-18 receptor upregulation was lower in st2(-/-) T cells, and linked to reduced... | DisGeNET | Detail |
| IL-6, IL-9, CCL24, CCL18, IL-10, IFN-γ, and CCL2 were highly increased (>6-fold); 26 genes were mode... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These data demonstrate a new mechanism by which helminth infection and the products derived during t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The study indicated that low IFN-γ expression probably impairs host immune response to HBV, renderin... | DisGeNET | Detail |
| The frequency of CD4(+) interferon-γ-positive T cells was negatively associated with serum HBV DNA l... | DisGeNET | Detail |
| Circulating CD56dim natural killer cells and CD56+ T cells that produce interferon-γ or interleukin-... | DisGeNET | Detail |
| Furthermore, we found that these cells could suppress hepatitis B virus-specific CD8(+) T cell respo... | DisGeNET | Detail |
| HBV‑specific interferon‑γ enzyme‑linked immunospot (IFN‑γ ELISPOT) assay and HBV‑specific T‑cell pro... | DisGeNET | Detail |
| IFN-γ +874A/T polymorphism also increased HBV-induced HCC risk (OR=1.42; 95% CI 1.08-1.87; P=0.01). | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Depending on KIR2DS4 expression (presence or absence) on cell surface, NK cells from 43 individuals ... | DisGeNET | Detail |
| Following qRT-PCR setup and run, the level of human IFN-γ transcript is normalized to CD8 transcript... | DisGeNET | Detail |
| Vaccine recipients with undetectable residual viremia at week 8 had higher frequencies of HIV-specif... | DisGeNET | Detail |
| The A to G hyper-mutation pattern observed in ADAR1 over-expressing cells in vitro was similar to th... | DisGeNET | Detail |
| Immune-correlates analysis of an HIV-1 vaccine efficacy trial reveals an association of nonspecific ... | DisGeNET | Detail |
| We demonstrate antigen-specific upregulation of IFNγ and IL-2 mRNAs in HIV- and CMV-specific T cells... | DisGeNET | Detail |
| Patient HLA-type, longitudinal CD8+ T-cell responses measured by IFN-γ ELISpot and longitudinal HIV-... | DisGeNET | Detail |
| Polymorphisms in the IFNγ, IL-10, and TGFβ genes may be associated with HIV-1 infection. | DisGeNET | Detail |
| Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of ... | DisGeNET | Detail |
| Following IL-12 stimulation, IFNγ expression was lower in HIV-HPgV co-infected subjects compared to ... | DisGeNET | Detail |
| HIV-specific CD8(+) T cells secreted little interferon-γ, underwent rapid apoptosis, and failed to u... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The CART-33 infusion alone induced rigorous chills and fevers; drastic fluctuations of his preexisti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| IFN-γ inhibited cTFH cell function in vitro and in vivo, as corroborated by hypergammaglobulinemia i... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of interferon-γ in decidual natural killer cells from women with hypertensive disorder co... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and protein, a key chemokin... | DisGeNET | Detail |
| In contrast, CMV-seropositive young adults exhibited enhanced antibody responses to influenza vaccin... | DisGeNET | Detail |
| The cross-reactivity of influenza B virus-specific polyclonal CD8+ cytotoxic T-lymphocyte (CTL) popu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we investigated the role of endogenous IFN-γ deficiency in adenomatous polyposis coli (Apc)-me... | DisGeNET | Detail |
| Our results demonstrate that ATG5 plays important roles in intestinal tumor growth and combination o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Frequency of TGF- β and IFN- γ genotype as risk factors for acute kidney injury and death in intensi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The redirection of the immune response elicited against the LiPABP family (from IL-10 towards IFN-γ ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Evaluation of IFN-γ polymorphism in visceral leishmaniasis. | DisGeNET | Detail |
| Leishmania specific CD4 T cells release IFNγ that limits parasite replication in patients with visce... | DisGeNET | Detail |
| The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated IL-10 production but... | DisGeNET | Detail |
| Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmania... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Functional characterization of LiTAPs by interferon-γ ELISPOT (Enzyme-Linked ImmunoSpot) and intrace... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In lung CD4+ T cells of most COPD subjects, relative to lung CD4+ T cells in smokers with normal spi... | DisGeNET | Detail |
| We found decreased levels of the transcription factor T-box expressed in T cells (T-bet or Tbx21) an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Furthermore, similarities between disease states in ARE-Del(-/-) mice and SLE patients suggest that ... | DisGeNET | Detail |
| Aberrant IFN-γ regulation appears to play an important role in anti-CAF-1 antibody production in SLE... | DisGeNET | Detail |
| Blockade of interferon-γ normalizes interferon-regulated gene expression and serum CXCL10 levels in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These responses resulted in the generation of IFN-γ-secreting cytotoxic lymphocytes and the producti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This data provides a starting point for functional and genetic analysis of the TNF and IFN-γ genomic... | DisGeNET | Detail |
| Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism haplotypes of IFN-α rec... | DisGeNET | Detail |
| We observed transcriptional up-regulation in many pathways, including type I interferon, interferon ... | DisGeNET | Detail |
| In this review we consider findings from the clinical disease, in vitro models and the murine counte... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Effects of suppressor of cytokine signaling 1 silencing on human melanoma cell proliferation and int... | DisGeNET | Detail |
| IFNγ-induced PD-L1 expression in cultured melanomas was assessed in parallel according to BRAF statu... | DisGeNET | Detail |
| Transcriptional signatures of both acute and chronic melioidosis revealed upregulation of iNOS in ti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Stimulated PBMC-produced IFN-γ and TNF-α are associated with altered relapse risk in multiple sclero... | DisGeNET | Detail |
| Genetic variation in PBMC-produced IFN-γ and TNF-α associations with relapse in multiple sclerosis. | DisGeNET | Detail |
| IL-17-producing CD4(+) T (Th17) cells, along with IFN-γ-expressing Th1 cells, represent two major pa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Several GO terms including the cellular response to interferon-γ, platelet degranulation, chemokine ... | DisGeNET | Detail |
| Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of ... | DisGeNET | Detail |
| Human inborn errors of immunity mediated by the cytokines interleukin-17A and interleukin-17F (IL-17... | DisGeNET | Detail |
| Overall, 82.9% of children with Gram-negative bacterial infections were accompanied by marked increa... | DisGeNET | Detail |
| Of the major polarizing T-cell cytokines, only IFNγ mRNA increases with mycosis fungoides progressio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Chronically elevated levels of IFN-γ resulted in progressive multiorgan inflammation and two copies ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We found the induction of myocarditis was associated with the upregulation of Col I, α-SMA, Gal-3, I... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Patients with narcolepsy were also found to have increased levels of interferon-gamma production in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish either presence of br... | DisGeNET | Detail |
| IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by... | DisGeNET | Detail |
| We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 ligand) and infiltrat... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These results uncover a dialogue regulated by interactions among T cell IFNγ and adipocyte MHCII and... | DisGeNET | Detail |
| We investigated in 102 T2D patients the association of the cytokine polymorphisms in the TNF-α, IL-1... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Unbiased analyses by Pathway Studio of the gene sets obtained by discrimination of RA from OA and CG... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Administration of MSCs alone significantly reduced pancreatic injury and inflammation, as reflected ... | DisGeNET | Detail |
| The CART-33 infusion alone induced rigorous chills and fevers; drastic fluctuations of his preexisti... | DisGeNET | Detail |
| CD30 as a molecular marker that transiently expresses on IFN-γ-producing T cells, may participate in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Th1-polarized host response, mediated by IFN-γ, has been associated with increased severity of perio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Neuronal pheochromocytoma (PC12) cells induced with amyloid-β peptide 1-42 and interferon-γ showed r... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The serum concentrations of tumor necrosis factor alpha (median 114.5 pg/ml, range 49.1-897.9 pg/ml)... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In vitro, IFN-γ administration inhibited Apc-mutated HT-29 colon cancer cell proliferation and had n... | DisGeNET | Detail |
| Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmania... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Expression of interferon-γ in decidual natural killer cells from women with hypertensive disorder co... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Analysis of mRNA transcripts of unstimulated lung CD4+ T cell among all subjects identified two dist... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| IFN-γ CA microsatellite polymorphism is associated with susceptibility to respiratory syncytial viru... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The miRNA profiles of human rhabdomyosarcoma cells treated with interferon (IFN-)-α or IFN-γ were co... | DisGeNET | Detail |
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| Genotype-mRNA expression correlation analysis revealed that the IRF8 protective allele was associate... | DisGeNET | Detail |
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| A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and ac... | DisGeNET | Detail |
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| High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
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| While the elderly group exhibited robust changes in immune activity such as increased production of ... | DisGeNET | Detail |
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| Evaluation of IFN-γ polymorphism+874 T/A in patients with recurrent tonsillitis by PCR real time mis... | DisGeNET | Detail |
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| These findings point to the crucial role of the IFNγ/STAT1 signal pathway in the evolutionary combat... | DisGeNET | Detail |
| Here, we investigated IFN-γ and miR-29a expression dynamics of CD4(+) T cells from patients during a... | DisGeNET | Detail |
| All mice showed strong antibody responses to the InsB protein, and splenocytes stimulated with InsB ... | DisGeNET | Detail |
| CpG-18 methylation level, TLR2 expressions on monocyte/NK cell, and TNF-α/IFN-γ levels were all reve... | DisGeNET | Detail |
| Collectively, these data validate p300 as a target of miR-132 and miR-26a, and demonstrate a mechani... | DisGeNET | Detail |
| The high expressions of TNF-α, IFN-γ in the spinal tuberculous focus were associated with protective... | DisGeNET | Detail |
| Osteopontin (OPN), interferon-γ-induced protein 10 kDa (IP-10), and neutrophil counts were found to ... | DisGeNET | Detail |
| Diagnostic performance of a cytokine and IFN-γ-induced chemokine mRNA assay after Mycobacterium tube... | DisGeNET | Detail |
| High concentrations of type I IFNs may block B cell responses or lead to the production of immunosup... | DisGeNET | Detail |
| The adaptive immune response in Mycobacterium tuberculosis is predominantly mediated by the interfer... | DisGeNET | Detail |
| Contribution of a heparin-binding haemagglutinin interferon-gamma release assay to the detection of ... | DisGeNET | Detail |
| There are positive associations between the IFN-γ -874 polymorphism and TB and between the IL10 - 10... | DisGeNET | Detail |
| High level of IFN-γ released from whole blood of human tuberculosis infections following stimulation... | DisGeNET | Detail |
| In conclusion, our results suggest that increased levels of IL-37 in patients with TB are associated... | DisGeNET | Detail |
| Here, we show that active human TB infection up-regulates CD244 and CD244 signaling-associated molec... | DisGeNET | Detail |
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| Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tuberculosis. | DisGeNET | Detail |
| Association study of polymorphisms in interferon-γ receptor genes with the risk of pulmonary tubercu... | DisGeNET | Detail |
| Furthermore, combinations of polymorphisms with IFN-γ -874 were associated with LTBI, whereas combin... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Here, we tested the hypothesis that cell-specific delivery of IFN-γ to platelet-derived growth facto... | DisGeNET | Detail |
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| In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and protein, a key chemokin... | DisGeNET | Detail |
| Pretreatment serum interferon gamma inducible protein-10 as biomarker of fibrosis and predictor of v... | DisGeNET | Detail |
| Interferon-γ (IFN-γ) and signal transducers and activators of transcription (STATs) each play an imp... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Isolated PBMCs from O. volvulus-infected individuals (164 MF(+) and 46 a-MF) and non-infected volunt... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Plasmatic tumor necrosis factor-β and interferon-γ were higher in DEB patients than in HCs (P = 0.04... | DisGeNET | Detail |
| Expanded CD3(+) T-cells with stable and high-level transgene expression (~95%) produced interferon-γ... | DisGeNET | Detail |
| In this study, we show that D393-CD20 is translated in malignant B cells and that D393-CD20 specific... | DisGeNET | Detail |
| CD107a degranulation and intracellular IFNγ production were also enhanced in CAR(+) exPBNK in respon... | DisGeNET | Detail |
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| Here, we tested the hypothesis that cell-specific delivery of IFN-γ to platelet-derived growth facto... | DisGeNET | Detail |
| Whereas M. tuberculosis-specific IFN-γ expression was similar during TB chemotherapy, superantigen s... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strategy for the treatment... | DisGeNET | Detail |
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| Molecular network analysis of these and other cleft lip/palate related module genes suggests that th... | DisGeNET | Detail |
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| IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P < 0.05). | DisGeNET | Detail |
| To explore the relationship between methylation of interferon gamma (IFN-γ) gene and tumorigenesis i... | DisGeNET | Detail |
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| Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IFN-γ) of T cells co-c... | DisGeNET | Detail |
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| To investigate the expression of TNF-α, IFN-γ, TGF-β, and IL-4 in the spinal tuberculous focus and i... | DisGeNET | Detail |
| Assess the value of baseline interferon-γ-inducible protein-10 (IP-10) levels as a noninvasive maker... | DisGeNET | Detail |
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| Adoptive T cell therapy combined with intralesional administrations of TG1042 (adenovirus expressing... | DisGeNET | Detail |
| In the present study we reveal a combination of IFN-γ-irreversible structural and epigenetic defects... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Furthermore, CALR/MAGE-A3-infected DCs stimulated CD8(+) cytotoxic T lymphocytes, which in turn secr... | DisGeNET | Detail |
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| IFN-γ mRNA levels were even higher in CA tissues than in severe CIN tissues (P < 0.05). | DisGeNET | Detail |
| Methylation patterns of the IFN-γ gene in cervical cancer tissues. | DisGeNET | Detail |
| B7-H4 is overexpressed in human cervical cancers, and it is associated with lower numbers of tumor-i... | DisGeNET | Detail |
| Interferon gamma +874 T/A polymorphism increases the risk of cervical cancer: evidence from a meta-a... | DisGeNET | Detail |
| Association Study of Single-Nucleotide Polymorphisms of STAT2/STAT3/IFN-γ Genes in Cervical Cancer i... | DisGeNET | Detail |
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| Furthermore, MDSCs from ACS patients were more potent suppressors of T-cell proliferation and IFN-γ ... | DisGeNET | Detail |
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| Interferon γ was identified as a significant upstream regulator of the expression changes for RR and... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| However, we found that variants rs692527 (P = 0.022) and rs34856358 (P = 0.022) of the MRC1 gene wer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Apoptosis, caspase activity, and cytokine production (IL-6, IL-10, TNF-β, and IFN-γ) of T cells co-c... | DisGeNET | Detail |
| Immune abnormalities such as decreased lymphocyte counts, inverted CD4/CD8 T-cell ratio and increase... | DisGeNET | Detail |
| The methylation rates of the IFN-γ gene were significantly higher in cervical cancer tissues (15/43,... | DisGeNET | Detail |
| Likewise, the IFN-γ expression levels in CIN II/III tissues with methylation (0.87 ± 0.16, n = 5) we... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with the expansion of CD3(-... | DisGeNET | Detail |
| Gastric infections led by Hp induce a Th-1 cellular immune response, regulated mainly by the express... | DisGeNET | Detail |
| Helicobacter pylori Outer Membrane Protein 18 (Hp1125) Is Involved in Persistent Colonization by Eva... | DisGeNET | Detail |
| Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total cell counts and eosin... | DisGeNET | Detail |
| IFN-γ CA microsatellite polymorphism was associated with the susceptibility of Chinese Han children ... | DisGeNET | Detail |
| Together, the results of this study identify environmental and genetic factors that influence RSV pa... | DisGeNET | Detail |
| EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-dr... | DisGeNET | Detail |
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| In addition, decreased numbers of CD4+ and CD8+ T lymphocytes and increased levels of TNF-α, IL-6 an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Kidneys with crescentic GN contained CD4(+) cells responding to α3IV-NC1 with the production of IFN-... | DisGeNET | Detail |
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| Serum IFN-γ levels were significantly reduced in EBV/HCV patients (3.86 pg/mL) compared to CHC patie... | DisGeNET | Detail |
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| Role of IFN-γ and IL-6 cytokines and their association in determining susceptibility to chronic idio... | DisGeNET | Detail |
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| The hypermethylation of IFN-γ gene may be related with tumorigenesis of cervical cancer. | DisGeNET | Detail |
| Interferon-γ (IFN-γ) and signal transducers and activators of transcription (STATs) each play an imp... | DisGeNET | Detail |
| EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-dr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish either presence of br... | DisGeNET | Detail |
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| It suggested that the Runx3 and Th1-associated factors including T-bet and IFN-γ synchronization dec... | DisGeNET | Detail |
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| Th1-polarized host response, mediated by IFN-γ, has been associated with increased severity of perio... | DisGeNET | Detail |
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| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
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| Risk model incorporating donor IL6 and IFNG genotype and gastrointestinal GVHD can discriminate pati... | DisGeNET | Detail |
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| Significantly, AA homozygous genotype was dominant in chronic hepatitis B cases in IFN-γ+874 and IL-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Genetic variations in TGF-β and IFN-γ may interfere with proinflammatory cytokine production and, co... | DisGeNET | Detail |
| Following disease induction, daily systemic administration of human recombinant Anx-A1 (hrAnx-A1), d... | DisGeNET | Detail |
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| Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total cell counts and eosin... | DisGeNET | Detail |
| The reduced SK lesion severity was reflected by increased phosphatidylinositol-3,4,5-trisphosphate 5... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| A subset of colorectal cancer displayed high infiltration with activated CD8(+) cytotoxic T lymphocy... | DisGeNET | Detail |
| Deficiency of interferon-gamma or its receptor promotes colorectal cancer development. | DisGeNET | Detail |
| A positive feedback loop between IRF1 and miR-29b may contribute to the sensitivity of CRC cells to ... | DisGeNET | Detail |
| We demonstrate that stronger secretion of CXCL10 (CXCR3 ligand) and CCL5 (CCR5 ligand) and infiltrat... | DisGeNET | Detail |
| Our results demonstrate that ATG5 plays important roles in intestinal tumor growth and combination o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total cell counts and eosin... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated IL-10 production but... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| IL-35, IL-17 and IFN-γ were elevated in TPE compared with MPE (all P<0.01). | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Concerning the key role of interferon-γ (IFN-γ) in the protective immunity against Mycobacterium tub... | DisGeNET | Detail |
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| A SNP-SNP interaction between IL-2-330 and IFN-γ-1615 was associated with an increased HCC risk (OR=... | DisGeNET | Detail |
| Interferon-γ +874A/T polymorphism and hepatocellular carcinoma risk: a meta-analysis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| ELISPOT assay showed that IL-35 reduced the proportion of IFN-γ-producing CD4+ T cells in TPE. | DisGeNET | Detail |
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| However, microbe-related protection from allergy seems to mainly depend on epigenetically controlled... | DisGeNET | Detail |
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| The serum concentrations of tumor necrosis factor alpha (median 114.5 pg/ml, range 49.1-897.9 pg/ml)... | DisGeNET | Detail |
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| Fewer T cells from patients with AAH produced interferon gamma in response to lipopolysaccharide, co... | DisGeNET | Detail |
| The Apc(Min/+)IFN-γ(+/-) mice presented with increased number and size of adenomas, and 41.7% of the... | DisGeNET | Detail |
| A significant association was found between lower measles-specific IFN-γ Enzyme-linked immunosorbent... | DisGeNET | Detail |
| Molecular analyses of the adenomas suggested that heterozygous deletion of IFN-γ promoted EGFR/Erk1/... | DisGeNET | Detail |
| Heterozygous deletion of ATG5 in Apc(Min/+) mice promotes intestinal adenoma growth and enhances the... | DisGeNET | Detail |
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| The upregulation of miR-155 expression was positively correlated with the percentage of Th1 cells an... | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
| STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic r... | DisGeNET | Detail |
| Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... | DisGeNET | Detail |
| Relationship of CD146 expression to secretion of interleukin (IL)-17, IL-22 and interferon-γ by CD4(... | DisGeNET | Detail |
| These data demonstrate that the molecular pathways IL-23/17 and IL-12/IFN-γ may represent subtypes o... | DisGeNET | Detail |
| In this issue of the European Journal of Immunology [Eur.J. Immunol.2015.45: 988-998], Olalekan et a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Unbiased analyses by Pathway Studio of the gene sets obtained by discrimination of RA from OA and CG... | DisGeNET | Detail |
| Expression of Interferon-γ Receptor Genes in Peripheral Blood Mononuclear Cells Is Associated With R... | DisGeNET | Detail |
| After 24weeks of treatment, percentages of IFNγ-induced pSTAT1+ and IL-10-induced pSTAT3+ monocytes ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These data provide a rationale to explore IFNγ therapy in ABPA as a corticosteroid-sparing treatment... | DisGeNET | Detail |
| It is crucial for naive T lymphocyte development, interferon-γ production, airway hyperresponsivenes... | DisGeNET | Detail |
| Association between FcεRIβ and IFN-γ Polymorphisms and Asthma in Asian Population: a Meta-Analysis. | DisGeNET | Detail |
| Healthy and asthmatic ASM cells were treated with TNF-α/IFN-γ for 24 hours in the presence or absenc... | DisGeNET | Detail |
| High IFN-γ and low SLPI mark severe asthma in mice and humans. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
| STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic r... | DisGeNET | Detail |
| Atorvastatin treatment increased the percentage and inhibitory ability of nTregs, decreased serum IF... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Type 1 Diabetes (T1D) is an autoimmune disease where local release of cytokines such as IL-1β and IF... | DisGeNET | Detail |
| Pathogenic functions of B cells in autoimmune diseases: IFN-γ production joins the criminal gang. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These immunized mice had significantly higher levels of IgG1 and IgG2a to rOmpB-4 and interferon-γ (... | DisGeNET | Detail |
| Th17 cells, mainly producing the cytokine IL-17, and Th1 cells, characterized by the production of t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic vi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| ROC curve analyses demonstrated that only IFN-γ has the ability to distinguish either presence of br... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| IFN-γ, an essential cytokine in the viral cell-mediated immune response, has been associated with th... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We found decreased levels of the transcription factor T-box expressed in T cells (T-bet or Tbx21) an... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs2266677 dbSNP
- Genome
- hg38
- Position
- chr12:68,154,768-68,159,740
- Variant Type
- snv
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