Annotation Detail
Information
- Associated Genes
- IFNG
- Associated Variants
-
IFNG MUTATION
IFNG MUTATION - Associated Disease
- tuberculosis
- Source Database
- DisGeNET
- Description
- Here, we show that active human TB infection up-regulates CD244 and CD244 signaling-associated molecules in CD8(+) T cells and that blockade of CD244 signaling enhances production of IFN-γ and TNF-α.
- Pubmed
- 26150504
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.103095470086808
Drugs