Annotation Detail

Information
Associated Genes
IFNG
Associated Variants
IFNG MUTATION
IFNG MUTATION
Associated Disease
obesity
Source Database
DisGeNET
Description
These results uncover a dialogue regulated by interactions among T cell IFNγ and adipocyte MHCII and NLRP3 inflammasome activity that appears to initiate and escalate adipose tissue inflammation during obesity.
Pubmed
25011057
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,RGD
DisGENET score for the Gene Disease association
0.0821715349766424
Drugs