Annotation Detail
Information
- Associated Genes
- IFNG
- Associated Variants
-
IFNG MUTATION
IFNG MUTATION - Associated Disease
- Leishmaniasis, Visceral
- Source Database
- DisGeNET
- Description
- The stimulation of peripheral blood mononuclear cells with r-LdODC up-regulated IL-10 production but not IFN-γ production from CD4(+) T cells in active as well as cured visceral leishmaniasis cases, indicating a pivotal role for r-LdODC in causing strong immune suppression in a susceptible host.
- Pubmed
- 25449949
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.122985860592883
Drugs