osteomyelitis

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Information
Disease name
osteomyelitis
Disease ID
DOID:1019
Description
"A bone inflammation disease that has_material_basis_in infection located_in bone or located_in bone marrow." [url:http\://en.wikipedia.org/wiki/Osteomyelitis, url:http\://my.clevelandclinic.org/disorders/osteomyelitis/hic_osteomyelitis.aspx, url:http\://www.mayoclinic.com/health/osteomyelitis/DS00759, url:http\://www.nlm.nih.gov/medlineplus/ency/article/000437.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04563325 Active, not recruiting Phase 4 Oral-only Antibiotics for Bone and Joint Infections in Children September 15, 2020 September 15, 2024
NCT03806166 Active, not recruiting N/A Short or Long Antibiotic Regimes in Orthopaedics February 21, 2019 August 7, 2024
NCT03802552 Completed Phase 1 Cefadroxil and Cephalexin Drug Levels and Dosing in Pediatric Musculoskeletal Infections May 1, 2019 April 30, 2021
NCT00714402 Completed Procalcitonin Level and Kinetics in Children With Bacterial Infections August 2008
NCT01098916 Completed N/A The RAD-HOME Project: a Pilot Study of Domiciliary Teleradiology June 2008 June 2009
NCT01336803 Completed Phase 2 Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI August 2011 October 2023
NCT03426761 Completed Phase 4 Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections January 25, 2018 December 31, 2022
NCT00428844 Completed Phase 2 Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci June 26, 2007 June 23, 2010
NCT03380403 Completed N/A A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients January 1, 2010 January 1, 2012
NCT03559530 Completed Acinetobacter Baumannii-related Osteomyelitis: Clinical and Epidemiological Characterization May 1, 2017 December 31, 2019
NCT05959590 Completed Phase 1 Ferumoxytol-enhanced Imaging of Osteomyelitis February 12, 2014 August 12, 2019
NCT02024282 Completed N/A Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care January 2013 December 2014
NCT02084147 Completed N/A PET-MRI in Diagnosing Patients With Cancer, Cardiac Diseases, or Neurologic Diseases March 7, 2013 October 2, 2018
NCT00324922 Completed Phase 3 Vancomycin Or Trimethoprim/Sulfamethoxazole for Methicillin-resistant Staphylococcus Aureus Osteomyelitis May 1, 2006 May 1, 2007
NCT02165579 Completed Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis June 2014 December 2014
NCT03898219 Completed Hematogenous Osteomyelitis in Childhood Can Relapse Dozens of Years in Adulthood January 1, 2015 April 6, 2016
NCT02308774 Completed Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (PCT) August 2014 October 2015
NCT02311452 Completed Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections January 2009
NCT02335905 Completed Phase 1/Phase 2 Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children June 3, 2015 June 16, 2020
NCT03846804 Completed N/A Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections September 1, 2019 June 2, 2022
NCT02463500 Completed UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repository January 2015 May 2023
NCT02685033 Completed Phase 2 Study on the Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Participants With Osteomyelitis March 15, 2016 December 12, 2017
NCT02736253 Completed Risk Factors for Three Critical Stages of the Diabetic Foot Infections June 2012 February 2015
NCT02968693 Completed Drug Delivery Devices for Osteomyelitis April 2011 July 2016
NCT00366249 Completed Phase 3 Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections (DFI) With a Substudy in Patients With Diabetic Foot Infections Complicated by Osteomyelitis. January 2007 March 2009
NCT00402064 Completed The Influence of Bisphosphonates in the Oral Cavity in Children March 2007 December 2008
NCT03808285 Completed Denosumab Related Osteonecrossi of the Jaw : : an Emergent and Potentially Complex Bone and Joint Infection January 1, 2013 December 31, 2018
NCT06283979 Not yet recruiting Phase 2 A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. July 1, 2024 December 1, 2025
NCT06402292 Not yet recruiting N/A Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute September 1, 2024 February 28, 2026
NCT05467644 Recruiting Treatment of Fracture Related Infection in Latin America. January 1, 2021 December 31, 2023
NCT02979951 Recruiting Fosfomycin i.v. for Treatment of Severely Infected Patients December 2016 December 2030
NCT03012529 Recruiting Phase 4 Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics January 22, 2018 September 30, 2024
NCT03594344 Recruiting N/A Additional Hyperbaric Oxygen After Lower Extremity Amputation July 4, 2018 December 31, 2025
NCT04538053 Recruiting Phase 4 BonE and Joint Infections - Simplifying Treatment in Children Trial June 1, 2021 December 2026
NCT04554108 Recruiting N/A Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses. May 31, 2021 May 31, 2025
NCT04936958 Recruiting RETR(Osteomyelitis) May 1, 2023 May 1, 2025
NCT05177107 Recruiting Phase 2 Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis November 24, 2021 December 2024
NCT05316298 Recruiting Diabetic Foot Osteomyelitis Treatment Using Gentamicin-loaded Calcium Sulfate-hydroxyapatite Biocomposite December 1, 2022 January 1, 2025
NCT05713149 Recruiting Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents February 19, 2023 February 1, 2027
NCT06084754 Recruiting N/A Effect of Pulsed Electromagnetic Field Stimulation on Localized Pediatric Osteomyelitis November 27, 2023 February 2024
NCT06096012 Recruiting Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA June 23, 2023 June 23, 2024
NCT01612962 Terminated Diagnostic Tests to Help Determine Osteomyelitis May 2011 February 2015
NCT03091439 Terminated Phase 2 Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Patients With Osteomyelitis May 15, 2017 August 31, 2017
NCT02168816 Terminated Phase 2 Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis March 19, 2014 February 2, 2017
NCT02099240 Terminated Early Phase 1 Patients Response to Early Switch To Oral:Osteomyelitis Study March 6, 2014 November 7, 2018
NCT02128256 Unknown status Phase 4 CERAMENT™|G - Bone Healing and Re-infection Prophylaxis May 2014 May 2017
NCT01137903 Unknown status N/A Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers April 2010 November 2011
NCT04945434 Unknown status N/A Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis September 1, 2011 June 30, 2021
NCT04141787 Unknown status Phase 4 Ceftriaxone as Home IV for Staph Infections July 11, 2019 March 30, 2024
NCT04229511 Unknown status Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients April 2020 November 2021
NCT02005068 Withdrawn Phase 4 Ceftaroline in the Treatment of Bone and Joint Infections April 2013 July 2014
NCT02344511 Withdrawn Phase 3 Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis March 2016 April 2019
NCT03787862 Withdrawn Investigation of the Use of Hyperspectral Imaging in Foot Surgery Patients June 13, 2014 June 13, 2015
Disase is a (Disease Ontology)
DOID:3342
Cross Reference ID (Disease Ontology)
GARD:7286
Cross Reference ID (Disease Ontology)
ICD9CM:730.1
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:203181001
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0008707
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0002754
ICD10 preferred id (Insert disease from ICD10)
D0010773
ICD10 class code (Insert disease from ICD10)
M86
MeSH unique ID (MeSH (Medical Subject Headings))
D010019