Annotation Detail
Information
- Associated Genes
- IFNG
- Associated Variants
-
IFNG MUTATION
IFNG MUTATION - Associated Disease
- Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
- Source Database
- DisGeNET
- Description
- Combined anti-IL-4 and anti-RSV siRNAs were able to significantly reduce total cell counts and eosinophilia in bronchoalveolar lavage fluid, development of airway hyperresponsiveness, and airway inflammation and to downregulate IL-4 mRNA expression and RSV viral RNA, but to upregulate IFN-γ levels in lung tissues.
- Pubmed
- 24655063
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
Drugs