malignant mesothelioma (Cancer)
Information
- Disease name
- malignant mesothelioma
- Disease ID
- DOID:1790
- Description
- "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs." [url:http\://cancergenome.nih.gov/cancersselected/Mesothelioma, url:http\://www.cancer.gov/dictionary?CdrID=44323, url:http\://www.merriam-webster.com/medlineplus/mesothelioma, url:https\://en.wikipedia.org/wiki/Mesothelioma]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05538572 | Active, not recruiting | Phase 1 | A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors | December 27, 2022 | December 2024 |
| NCT03678350 | Active, not recruiting | Phase 1 | Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery | September 17, 2021 | November 13, 2025 |
| NCT00002608 | Completed | Phase 2 | Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors | May 1994 | April 2005 |
| NCT00003263 | Completed | Phase 1 | Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | August 1996 | November 2000 |
| NCT00003723 | Completed | Phase 2 | S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery | February 1999 | December 2007 |
| NCT00003974 | Completed | Phase 1 | Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-small Cell Lung Cancer or With Stage I or Stage II Mesothelioma | August 1997 | November 2000 |
| NCT00004033 | Completed | Phase 2 | Liposomal-Cisplatin Analogue (L-NDDP) in Treating Patients With Malignant Pleural Mesothelioma | September 1998 | |
| NCT00004183 | Completed | Phase 2 | Capecitabine in Treating Patients With Malignant Mesothelioma | November 2000 | January 2006 |
| NCT00004254 | Completed | Phase 2 | Raltitrexed in Treating Patients With Malignant Mesothelioma That Cannot Be Surgically Removed | November 1999 | |
| NCT00004920 | Completed | Phase 3 | Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura | November 1999 | |
| NCT00005636 | Completed | Phase 3 | Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery | November 1999 | November 2000 |
| NCT00006014 | Completed | Phase 2 | SU5416 in Treating Patients With Malignant Mesothelioma | August 2000 | February 2009 |
| NCT00006981 | Completed | Phase 1 | Immunotoxin Therapy in Treating Patients With Advanced Cancer | December 2000 | |
| NCT00002475 | Completed | Phase 2 | Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer | April 1991 | June 2009 |
| NCT00075699 | Completed | Phase 3 | Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma | September 2003 | |
| NCT00227630 | Completed | Phase 2 | Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | July 2005 | |
| NCT00334594 | Completed | Phase 2 | Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | November 14, 2005 | January 23, 2018 |
| NCT00354393 | Completed | Phase 2 | Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma | August 2002 | June 2009 |
| NCT00372840 | Completed | N/A | Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer | May 2006 | March 2013 |
| NCT00398138 | Completed | Phase 1 | Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma | October 2006 | June 2009 |
| NCT00458913 | Completed | Phase 2 | Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesothelioma | February 2007 | March 2012 |
| NCT00509041 | Completed | Phase 2 | Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma | August 2007 | December 2012 |
| NCT00513877 | Completed | Phase 2 | Bortezomib in Treating Patients With Malignant Pleural Mesothelioma | May 2006 | |
| NCT00541073 | Completed | Phase 2 | Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgery | June 2007 | |
| NCT00634205 | Completed | Phase 2 | Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma | July 2006 | June 2010 |
| NCT00770120 | Completed | Phase 2 | S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery | December 2008 | April 2014 |
| NCT00821860 | Completed | Phase 3 | Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma | September 2003 | May 2013 |
| NCT00897247 | Completed | Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite | January 2007 | October 2013 | |
| NCT00897442 | Completed | Collecting Tumor Samples From Patients With Gynecological Tumors | June 1992 | ||
| NCT01085630 | Completed | Phase 2 | Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy | April 2010 | April 1, 2021 |
| NCT01291420 | Completed | Phase 1/Phase 2 | Dendritic Cell Vaccination for Patients With Solid Tumors | May 3, 2010 | May 5, 2018 |
| NCT01655225 | Completed | Phase 1 | A Study of LY3023414 in Participants With Advanced Cancer | July 31, 2012 | February 2, 2022 |
| NCT02300883 | Completed | Observational Prospective Analysis of Biological Characteristics of Mesothelioma Patients | April 2011 | January 2018 | |
| NCT02349412 | Completed | Phase 3 | Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers | April 2015 | July 15, 2019 |
| NCT03684486 | Completed | N/A | Rehabilitation by Effort for Patients With Advanced Bronchial Cancer | February 1, 2012 | July 24, 2019 |
| NCT00006231 | Completed | Phase 3 | Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma | February 1998 | December 2002 |
| NCT00017186 | Completed | Phase 2 | Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma | July 2001 | May 2008 |
| NCT00019825 | Completed | Phase 1 | Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura | October 1999 | |
| NCT00020124 | Completed | Phase 1 | Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungs | June 2000 | December 2002 |
| NCT00024076 | Completed | Phase 2 | Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer | May 2000 | |
| NCT00030745 | Completed | Phase 2 | Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung | June 2000 | August 2003 |
| NCT00053885 | Completed | Phase 2 | PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesothelioma | July 2003 | June 2006 |
| NCT00054002 | Completed | Phase 2 | Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma | March 1999 | December 2010 |
| NCT00062283 | Completed | Phase 2 | Alanosine in Treating Patients With Cancer | March 2003 | December 2009 |
| NCT00066651 | Completed | Phase 1 | Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors | July 2003 | |
| NCT03874455 | No longer available | Tazemetostat Expanded Access Program for Adults With Solid Tumors | |||
| NCT03007030 | Recruiting | Phase 2 | Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery | April 5, 2017 | April 30, 2025 |
| NCT06256055 | Recruiting | Phase 1 | Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors | March 5, 2024 | April 2025 |
| NCT06057935 | Recruiting | Phase 2 | A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma | September 21, 2023 | September 21, 2028 |
| NCT00898547 | Terminated | Biomarkers of Angiogenesis and Disease in Patients With Unresectable Malignant Mesothelioma Treated on Clinical Trial CALGB-30107 | November 2005 | August 2015 | |
| NCT00027508 | Terminated | Phase 2 | Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma | July 2001 | February 2002 |
| NCT00003508 | Terminated | Phase 2 | Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma | March 8, 1996 | April 26, 2005 |
| NCT04173338 | Terminated | Phase 1 | Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma | January 23, 2020 | March 28, 2022 |
| NCT03558932 | Unknown status | IP3R Modulation by Cancer Genes in Mesothelioma | January 2019 | June 2024 | |
| NCT00253409 | Unknown status | N/A | Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By Surgery | May 2005 | |
| NCT00899613 | Unknown status | Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia | April 2007 | ||
| NCT03852823 | Unknown status | Phase 1 | Study of Recombinant Human Anti-PD-1 Monoclonal Antibody in Patients With Advanced Tumours | May 23, 2019 | March 2023 |
| NCT02580747 | Unknown status | Phase 1 | Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso | October 2015 | November 2018 |
| NCT01649024 | Unknown status | Phase 2 | A Clinical Study With Tremelimumab as Monotherapy in Malignant Mesothelioma | May 2009 | June 2013 |
| NCT00002465 | Unknown status | Phase 1/Phase 2 | High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma | December 1987 | |
| NCT01655888 | Unknown status | Phase 2 | The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesothelioma | July 2012 | January 2015 |
| NCT00003034 | Unknown status | Phase 3 | ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen | May 1997 | |
| NCT00024271 | Unknown status | Phase 2 | Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer | May 2001 | |
| NCT00030459 | Unknown status | Phase 2 | Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma | November 2000 | |
| NCT00006216 | Unknown status | Phase 1 | Vaccine Therapy and Ganciclovir in Treating Patients With Mesothelioma | August 1997 | |
| NCT00733252 | Withdrawn | Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease | April 2008 | February 2011 |
- Disase is a (Disease Ontology)
- DOID:0050687
- Cross Reference ID (Disease Ontology)
- MESH:D000086002
- Cross Reference ID (Disease Ontology)
- MIM:156240
- Cross Reference ID (Disease Ontology)
- NCI:C27926
- Cross Reference ID (Disease Ontology)
- NCI:C4456
- Cross Reference ID (Disease Ontology)
- NCI:C7865
- Cross Reference ID (Disease Ontology)
- NCI:C8420
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:109378008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0278752
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0345967
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0392400
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C1332338
- Exact Synonym (Disease Ontology)
- advanced malignant mesothelioma
- Exact Synonym (Disease Ontology)
- asbestos-related malignant mesothelioma
- Exact Synonym (Disease Ontology)
- Diffuse malignant Mesothelioma
- Exact Synonym (Disease Ontology)
- malignant tumor of Mesothelium
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0100001