Annotation Detail

Information
Associated Genes
IFNG
Associated Variants
IFNG MUTATION
IFNG MUTATION
Associated Disease
Chronic Obstructive Airway Disease
Source Database
DisGeNET
Description
In lung CD4+ T cells of most COPD subjects, relative to lung CD4+ T cells in smokers with normal spirometry: (a) stimulation induced minimal IFN-γ or other inflammatory mediators, but many subjects produced more CCL2; (b) the T effector memory subset was less uniformly predominant, without correlation with decreased IFN-γ production.
Pubmed
24805101
Section of the abstract supporting the evidence
UNLABELLED
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00318135759484294
Drugs