stage III melanoma

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Information
Disease name
stage III melanoma
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03719131 Active, not recruiting Phase 2 Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy June 5, 2019 September 13, 2024
NCT05079113 Active, not recruiting Leveraging ctDNA Analysis to Improve Early Detection of Cancer Recurrence in the High-Risk Melanoma Setting October 1, 2019 April 2025
NCT03200847 Active, not recruiting Phase 1/Phase 2 Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma October 31, 2017 August 2024
NCT00019890 Completed Phase 2 Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma March 2007
NCT00030615 Completed Phase 1 Decitabine in Treating Patients With Advanced Solid Tumors December 2001
NCT00074308 Completed Phase 1/Phase 2 Imatinib Mesylate and Bevacizumab in Treating Patients With Advanced Melanoma or Other Advanced Cancers October 2003 July 2009
NCT00089362 Completed Phase 1 Alvespimycin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors July 2004
NCT00119249 Completed Phase 2 Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery June 2005
NCT00217542 Completed Phase 1 Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery July 2005
NCT00349206 Completed Phase 1 Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma April 2006 February 2012
NCT00450255 Completed Phase 2 VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery June 2007 January 2011
NCT01107665 Completed Phase 2 Pazopanib and Paclitaxel as First-Line Treatment for Subjects With Unresectable Stage III and Stage IV Melanoma August 2010 February 2018
NCT00003647 Completed Phase 3 Chemotherapy With or Without Immunotherapy in Treating Patients With Stage III or Stage IV Melanoma July 1998 September 2002
NCT00003789 Completed Phase 3 Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg March 1999
NCT00003646 Completed Phase 2 Gene Therapy in Treating Patients With Stage III or Stage IV Melanoma August 1998 May 2002
NCT01376713 Completed Phase 2 Anti-CD20 (Cluster of Differentiation Antigen 20) Therapy to Treat Metastatic Melanoma June 2011 May 2015
NCT01726738 Completed Phase 2 LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations April 4, 2013 September 17, 2020
NCT02073123 Completed Phase 1/Phase 2 Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma July 2014 July 3, 2019
NCT02306850 Completed Phase 2 Neoadjuvant Pembrolizumab for Unresectable Stage III and Unresectable Stage IV Melanoma January 2015 June 8, 2018
NCT02676869 Completed Phase 1 Phase 1 Study of IMP321 (Eftilagimod Alpha) Adjuvant to Anti-PD-1 Therapy in Unresectable or Metastatic Melanoma April 2016 December 2019
NCT02794636 Completed Interferon Toxicities in Melanoma Treatment May 2014 November 2015
NCT04059224 Completed Phase 2 TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma January 28, 2019 June 30, 2023
NCT03385486 Recruiting Phase 1 Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors June 2, 2019 December 2024
NCT01026051 Terminated Phase 2 Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma October 2010 July 2012
NCT00082875 Terminated Phase 2 Cilengitide in Treating Patients With Unresectable or Metastatic Melanoma March 2004
NCT00087386 Terminated Phase 2 Tanespimycin in Treating Patients With Stage III-IV Melanoma June 2004
NCT00945269 Terminated Phase 1/Phase 2 Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma July 2009 January 2011
NCT01875653 Terminated Phase 3 Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma October 2014 January 2016
NCT01168050 Unknown status Phase 2 Efficacy of Nilotinib in First or Second Line Treatment of Primary Melanomas Stage III Unresectable Melanomas. July 2010 December 2013
NCT01851408 Withdrawn Phase 2 Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma April 2006 February 2012
NCT04703426 Withdrawn Phase 2 Sargramostim (GM-CSF) + PD-1 April 16, 2021 June 9, 2025