Chronic sinusitis
Information
- Disease name
- Chronic sinusitis
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05219968 | Active, not recruiting | Phase 3 | Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults | January 27, 2022 | September 15, 2024 |
| NCT00231062 | Completed | Phase 3 | Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR) | April 2005 | June 2006 |
| NCT00410735 | Completed | Phase 3 | Study of ONO-1078 in Patients With Chronic Sinusitis | December 2006 | |
| NCT00425620 | Completed | Phase 3 | Amphotericin B Suspension in Refractory Chronic Sinusitis | December 2006 | October 2007 |
| NCT00447837 | Completed | Phase 2 | Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitis | October 2006 | January 2008 |
| NCT05983003 | Completed | Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data | March 2015 | April 2024 | |
| NCT00626366 | Completed | N/A | Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison | March 12, 2008 | January 9, 2009 |
| NCT05035654 | Completed | Phase 2 | LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study) | November 23, 2021 | August 30, 2023 |
| NCT04754230 | Completed | Phase 4 | Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery | June 17, 2021 | February 20, 2022 |
| NCT04678856 | Completed | Phase 2 | Dupilumab in CRSsNP | December 2, 2020 | January 29, 2024 |
| NCT00840970 | Completed | N/A | A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic Rhinosinusitis | March 2008 | April 2009 |
| NCT04617223 | Completed | N/A | Results of Endoscopic Sinus Surgery in Management of Ophthalmological Complications of Chronic Rhino Sinusitis | April 13, 2021 | September 1, 2021 |
| NCT04418622 | Completed | Evolution of the Endonasal Microbiota in Patients With Chronic Rhinosinusitis | October 21, 2020 | November 15, 2021 | |
| NCT04163978 | Completed | Phase 2 | Nitric Oxide Releasing Sinus Irrigation (NOSi) to Treat Recalcitrant Chronic Rhinosinusitis (RCRS) | October 27, 2019 | May 3, 2022 |
| NCT00912405 | Completed | N/A | Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic Sinusitis | March 2009 | December 2009 |
| NCT00924404 | Completed | N/A | Xylitol Versus Saline in Chronic Sinusitis | May 2009 | August 2014 |
| NCT00939393 | Completed | N/A | Balloon Sinus Dilation In Office or OR | April 1, 2008 | July 1, 2010 |
| NCT00939471 | Completed | N/A | Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis | April 1, 2007 | May 1, 2010 |
| NCT00962689 | Completed | Clinical Study to Improve Diagnosis and Treatment of Sinusitis | August 2009 | November 2013 | |
| NCT01007799 | Completed | N/A | Vitamin D for Chronic Sinusitis | November 2009 | September 2011 |
| NCT04041609 | Completed | Phase 2 | LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study) | May 9, 2019 | February 4, 2021 |
| NCT03661346 | Completed | Phase 2 | Esmolol vs. Labetalol in Endoscopic Sinus Surgery | March 1, 2017 | March 30, 2018 |
| NCT01197612 | Completed | Phase 3 | Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis | September 2010 | June 2012 |
| NCT01253577 | Completed | Phase 3 | A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis | December 2009 | October 2010 |
| NCT01430026 | Completed | Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis | March 2011 | March 2012 | |
| NCT01525849 | Completed | N/A | Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up | December 2011 | May 2014 |
| NCT01525862 | Completed | N/A | XprESS Maxillary Balloon Dilation Study | December 2011 | January 2013 |
| NCT01564355 | Completed | N/A | Postoperative Systemic Corticosteroids When Utilizing a Steroid-Eluting Spacer Following Endoscopic Sinus Surgery | April 2012 | December 2013 |
| NCT01569048 | Completed | Phase 4 | Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery | March 2012 | February 2014 |
| NCT01608308 | Completed | N/A | Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery | July 2012 | September 2014 |
| NCT01700725 | Completed | Phase 2 | Gulf War Illness Nasal Irrigation Study | October 2012 | May 2017 |
| NCT01706484 | Completed | Phase 3 | Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic Rhinosinusitis | September 2012 | July 2014 |
| NCT01706952 | Completed | Phase 4 | Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery | December 2012 | December 2013 |
| NCT01732536 | Completed | Phase 2/Phase 3 | Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps | January 2013 | May 2014 |
| NCT03358329 | Completed | Phase 3 | Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE) | November 13, 2017 | January 17, 2019 |
| NCT01894503 | Completed | Phase 2 | Safety and Performance of the Steroid-Releasing S8 Sinus Implant | June 2013 | October 2013 |
| NCT02228720 | Completed | N/A | Clinical Evaluation of Propel Nova Sinus Implant in Peripheral Sinus Ostia | June 2014 | January 2015 |
| NCT02266810 | Completed | Phase 3 | Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal Sinus | September 2014 | October 2016 |
| NCT02291549 | Completed | Phase 3 | S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps | December 2014 | October 2016 |
| NCT02562924 | Completed | N/A | The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery | November 2015 | December 2017 |
| NCT02687438 | Completed | N/A | The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery | December 2015 | February 2016 |
| NCT02880514 | Completed | N/A | In-office Placement of the Propel Mini Sinus Implant in the Frontal Sinus Ostia | August 2016 | June 2017 |
| NCT02967731 | Completed | Phase 1 | 480 Biomedical Sinus Drug Depot | June 6, 2017 | May 18, 2018 |
| NCT04374448 | Not yet recruiting | N/A | Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery | January 1, 2023 | January 1, 2024 |
| NCT05454163 | Not yet recruiting | Post-radiotherapy Rhinosinusitis in Children | October 2022 | October 2025 | |
| NCT06070311 | Not yet recruiting | N/A | Wound Healing After Endoscopic Sinus Surgery | October 2023 | October 2025 |
| NCT06398899 | Not yet recruiting | N/A | Sugammadex v.s. Neostigmine/Glycopyrrolate | May 1, 2024 | January 31, 2025 |
| NCT04187976 | Recruiting | Eosinophils Endotypes in Chronic Airway Inflammatory Diseases | March 3, 2020 | March 2024 | |
| NCT04362501 | Recruiting | Phase 2 | Efficacy of Dupilumab for Patients With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) | October 15, 2020 | October 15, 2024 |
| NCT06036927 | Recruiting | Phase 2 | A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps | December 8, 2023 | September 2025 |
| NCT06020690 | Recruiting | N/A | A Clinical Study to Evaluate the Safety and Effectiveness of Novabel Bioabsorbable Steroid-releasing Stent for the Chronic Sinusitis | August 25, 2023 | September 9, 2025 |
| NCT06198894 | Recruiting | N/A | Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative Symptoms | January 10, 2024 | April 10, 2026 |
| NCT05295459 | Recruiting | Phase 3 | Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) | May 13, 2022 | December 15, 2024 |
| NCT04852562 | Recruiting | N/A | The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps | December 6, 2020 | December 6, 2024 |
| NCT06272123 | Recruiting | Endotypic Stability in CRS | January 1, 2024 | January 31, 2026 | |
| NCT00880516 | Recruiting | Genetic Factors in Chronic Sinusitis | April 1, 2009 | December 2024 | |
| NCT03336671 | Terminated | N/A | Management of Pediatric Chronic Rhinosinusitis in Asthmatic Children | July 1, 2017 | July 1, 2020 |
| NCT01066416 | Terminated | N/A | Effects of Endoscopic Sinus Surgery for Chronic Sinusitis on Asthma Control | July 2009 | December 2010 |
| NCT00140608 | Terminated | N/A | Efficacy of Seprapack Sinus Dressing Versus No Dressing in the Prevention of Intranasal Adhesions Following Sinus Surgery | June 2003 | May 2005 |
| NCT00754793 | Terminated | Phase 4 | Sinusitis and Facial Pain Disorders Anti-Depression Trial | January 2009 | December 2012 |
| NCT00852410 | Unknown status | Phase 3 | The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery | March 2009 | April 2010 |
| NCT03174483 | Unknown status | N/A | Radiologic Scoring of Patients With Chronic Sinusitis and Nasal Polyps | June 2017 | July 2018 |
| NCT03903432 | Unknown status | N/A | The Feasibility of Using MRI During ESS | May 15, 2019 | February 15, 2021 |
| NCT05156801 | Unknown status | N/A | Efficacy of ArchSinus, NasoPore & Propel to Prevent Post-Surgical MT Lateralization and Improve Symptomatic Outcomes | March 2022 | October 2023 |
| NCT05369039 | Unknown status | Phase 2 | Roflumilust in Chronic Rhinosinusitis With Nasal Polyposis. | June 2022 | March 2023 |
| NCT03472144 | Unknown status | Phase 3 | Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis | July 7, 2017 | December 7, 2019 |
| NCT01854619 | Unknown status | N/A | Photodynamic Therapy for the Treatment of Chronic Rhinosinusitis | May 2013 | March 2014 |
| NCT02812199 | Unknown status | N/A | Efficacy of Post-FESS Implantation of Composite Removable Sinus Stent to Prevent Post-Operative Complications | August 2016 | December 2017 |
| NCT04291118 | Unknown status | N/A | Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management | February 10, 2020 | October 1, 2021 |
| NCT02981017 | Withdrawn | N/A | Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure | November 1, 2016 | December 28, 2019 |
| NCT00841802 | Withdrawn | Phase 4 | Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study | July 2008 | June 30, 2019 |
| NCT01185808 | Withdrawn | N/A | Vitamin D Supplementation in Chronic Rhinosinusitis With Nasal Polyps | October 2013 | October 2013 |
| NCT00705354 | Withdrawn | N/A | Pilot Study To Evaluate A Pharmacologically Active Nasal Sponge Following Endoscopic Sinus Surgery | January 2009 | October 2010 |
| NCT00603785 | Withdrawn | Phase 4 | Effects of Anti-IgE Antibody Omalizumab on Patients With Chronic Sinusitis | January 2008 | April 2008 |
| NCT00671541 | Withdrawn | Phase 4 | Nasospore Stent For Use in Enodscopic Sinus Surgery | March 2006 | February 2012 |
| NCT03519061 | Withdrawn | Phase 2/Phase 3 | Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates | August 13, 2019 | October 1, 2019 |
| NCT00671281 | Withdrawn | N/A | The Effect of Tranexamic Acid on Intraoperative and Post-Operative Bleeding in Functional Endoscopic Sinus Surgery | October 2008 | December 2009 |
| NCT03729310 | Withdrawn | Early Phase 1 | Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis | March 2020 | May 26, 2020 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0011109
- MedGen concept unique identifier (MedGen Concept name)
- C0149516
- MedGen concept unique identifier (MedGen Concept name)
- C0748720
- MedGen unique identifier (MedGen Concept name)
- 101751
- MedGen unique identifier (MedGen Concept name)
- 906379
- ICD10 preferred id (Insert disease from ICD10)
- D0007976
- ICD10 class code (Insert disease from ICD10)
- J32