tonsillitis

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Information
Disease name
tonsillitis
Disease ID
DOID:10456
Description
"An upper respiratory tract disease which is characterized by inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat, painful or difficult swallowing, coughing, headache, myalgia, fever and chills." [url:http\://en.wikipedia.org/wiki/Tonsillitis, url:http\://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=tonsillitis]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03654742 Active, not recruiting N/A Intracapsular Tonsillectomy in Adults September 27, 2019 December 30, 2028
NCT00643149 Completed Phase 3 A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children May 2003 March 2004
NCT04230681 Completed Early Phase 1 Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery February 26, 2020 April 1, 2022
NCT04277299 Completed N/A Intelligent Customer-driven Solution for Children and Their Parents Undergoing Day Surgery August 12, 2020 February 3, 2022
NCT00643539 Completed Phase 4 Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat December 2002 July 2003
NCT04551196 Completed Phase 3 Management of Post-Tonsillectomy Pain in Pediatric Patients September 28, 2020 November 10, 2022
NCT00095368 Completed Phase 3 APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat October 2004 May 2005
NCT04653376 Completed Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases November 1, 2018 June 10, 2019
NCT05244226 Completed Phase 2 Pediatric Pain Optimization After Tonsillectomy April 8, 2022 May 10, 2023
NCT04016051 Completed Phase 3 Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections September 22, 2004 December 23, 2004
NCT00393744 Completed Phase 3 Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children October 2006
NCT02444533 Completed Phase 4 EXPAREL® for Pain After Tonsillectomy May 2015 May 2016
NCT02571075 Completed N/A Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea November 2013 August 23, 2017
NCT02712307 Completed Phase 4 Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci September 2015 June 2018
NCT00242281 Completed Phase 3 APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat November 2005 July 2006
NCT02858687 Completed N/A Improving the Diagnosis of Tonsillitis in Emergency Rooms February 26, 2013 October 27, 2022
NCT00547391 Completed Phase 4 Recurrent Throat Infections and Tonsillectomy November 2007 June 2011
NCT00570414 Completed N/A Airway Management in Children Undergoing Adenotonsillectomies March 2007 August 2008
NCT00583453 Completed Phase 2 Celecoxib as a Post-tonsillectomy Pain Medication October 2007 May 2016
NCT03337672 Completed N/A Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children December 5, 2017 December 17, 2018
NCT03377374 Completed N/A L. Reuteri ATCC PTA 5289 & L. Reuteri DSM 17938 for the Treatment of Children With Pharyngitis and/or Tonsillitis December 28, 2017 February 11, 2019
NCT03408704 Completed N/A Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat January 17, 2018 February 28, 2022
NCT03575377 Completed N/A Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery June 7, 2018 December 31, 2018
NCT05532228 Completed Evaluation of the Functional Impact of Adenotonsilectomy August 20, 2020 February 1, 2022
NCT00644293 Completed Phase 3 A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults January 2003 April 2004
NCT00654511 Completed Phase 4 Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy January 2005 October 2008
NCT00829972 Completed Vitamin D Levels in Children Undergoing Adenotonsillectomies and Controls January 1, 2009 November 1, 2009
NCT00926198 Completed Investigation of Clinical Spectrum, Bacterial Pathogens and Immune Response in Acute Pharyngotonsillitis May 2009 June 2010
NCT01267136 Completed Phase 4 A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy January 2011 May 2012
NCT01361399 Completed Phase 3 Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold November 30, 2004 May 28, 2005
NCT01465009 Completed Phase 4 Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold November 2003 March 2005
NCT01691690 Completed Phase 2 Analgesic Effect of IV Acetaminophen in Tonsillectomies October 2012 July 2016
NCT01695980 Completed N/A Laryngeal Mask Airway in Pediatric Adenotonsillectomy August 2012 March 29, 2022
NCT01721486 Completed Phase 4 Acetaminophen's Efficacy For Post-operative Pain September 2012 January 2015
NCT05656365 Recruiting Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders May 23, 2023 December 31, 2038
NCT03292068 Recruiting N/A Children Recovering From Tonsil Surgery January 1, 2019 December 1, 2022
NCT06326983 Recruiting N/A Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery May 9, 2024 April 1, 2026
NCT03625011 Recruiting Phase 4 Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy July 31, 2018 December 31, 2019
NCT04528173 Recruiting Phase 4 Opioid-Free Anesthetic for Tonsillectomy July 22, 2020 December 31, 2023
NCT03995628 Recruiting Phase 2 Steroids and Pain Control After Tonsillectomy December 18, 2018 July 2024
NCT05575401 Recruiting N/A Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy May 17, 2023 August 2024
NCT01919996 Terminated Phase 2 PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric Patients December 2013 November 2015
NCT00315042 Terminated Phase 3 TELI TON - Telithromycin in Tonsillitis March 2006 August 2006
NCT05279534 Terminated N/A Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections March 8, 2022 June 2, 2023
NCT02162433 Terminated Phase 4 The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation March 2015 April 23, 2018
NCT01193556 Terminated N/A PEAK PlasmaBlade TnA Versus Traditional Electrosurgery in Subcapsular Tonsillectomy July 2010 April 2012
NCT00315549 Terminated Phase 3 TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults February 2006 September 2006
NCT04646525 Unknown status The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs October 1, 2020 February 1, 2021
NCT00136877 Unknown status N/A Tonsillectomy in Recurrent Tonsillitis October 2001 December 2005
NCT00466544 Unknown status Phase 4 Randomized Controlled Study of Plasmaknife Tonsillectomy Versus Monopolar Tonsillectomy May 2007
NCT00636402 Unknown status N/A Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy March 2008 December 2008
NCT01193790 Unknown status Phase 2 Evaluation of Coblation Channeling in Treating Chronic Tonsillitis January 2011
NCT02205580 Unknown status Phase 4 Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children September 2014 December 2014
NCT02676583 Unknown status N/A Effectiveness of Tonsil Fossa Closure in Pain Relief After Tonsillectomy in Children February 2016 September 2017
NCT02848287 Unknown status N/A Influence of 0.75% Ropivacaine Topicalization on Emergence Agitation in Children August 2016 August 2017
NCT02972437 Unknown status Detection of Group A Streptococcus (GAS) in Oral Cavity December 2016 January 2018
NCT03137823 Unknown status N/A Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface November 22, 2017 July 1, 2019
NCT03323047 Unknown status Phase 4 Perioperative Tonsillectomy Protocol Development March 1, 2018 September 2021
NCT04083417 Unknown status Phase 4 Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment September 9, 2019 June 2021
NCT04164511 Unknown status Does Ice Cream Help With Post-tonsillectomy Pain November 1, 2019 July 1, 2020
NCT04297878 Unknown status N/A The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing Regimens of the Probiotic Supplement Streptococcus Salivarius K12 (Bactoblis®) in Adults March 5, 2020 January 1, 2022
NCT00459927 Withdrawn Phase 2/Phase 3 Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy July 2009
Disase is a (Disease Ontology)
DOID:974
Cross Reference ID (Disease Ontology)
ICD10CM:J35.01
Cross Reference ID (Disease Ontology)
ICD9CM:474.00
Cross Reference ID (Disease Ontology)
MESH:D014069
Cross Reference ID (Disease Ontology)
NCI:C116006
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:195665006
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:195794009
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0040425
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0149517
Exact Synonym (Disease Ontology)
chronic tonsillitis
Exact Synonym (Disease Ontology)
Throat infection - tonsillitis
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0011110
MeSH unique ID (MeSH (Medical Subject Headings))
D014069