biliary atresia
Information
- Disease name
- biliary atresia
- Disease ID
- DOID:13608
- Description
- "A cholestasis characterized by blockage of the ducts that carry bile from the liver to the gallbladder." [url:http\://en.wikipedia.org/wiki/Biliary_atresia, url:http\://www.nlm.nih.gov/medlineplus/ency/article/000215.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT06219993 | Active, not recruiting | Robot-assisted Modified Kasai Portoenterostomy Versus Open Kasai Portoenterostomy for Biliary Atresia | December 21, 2023 | December 30, 2025 | |
| NCT02922751 | Active, not recruiting | FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE) | November 16, 2016 | December 2024 | |
| NCT00294684 | Completed | N/A | A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy | November 2005 | January 2013 |
| NCT05517317 | Completed | Phase 1 | Autologous BMNC Infusion for Liver Cirrhosis in Children With BA | January 1, 2015 | May 30, 2022 |
| NCT00166868 | Completed | N/A | Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy | December 2003 | July 2012 |
| NCT01063699 | Completed | N/A | Survival With Own Liver of Conventional Versus Laparoscopic Kasai for Biliary Atresia | August 2003 | September 2007 |
| NCT01322386 | Completed | Phase 1 | Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin | May 2007 | January 2012 |
| NCT01443572 | Completed | N/A | The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation | September 2011 | July 2014 |
| NCT01854827 | Completed | Phase 1/Phase 2 | Safety Study of Intravenous Immunoglobulin (IVIG) Post-Portoenterostomy in Infants With Biliary Atresia | October 2013 | July 2016 |
| NCT02292862 | Completed | Maternal Microchimerism in Lymph Nodes of Infants With Biliary Atresia at Time of Kasai's Operation | November 2012 | November 2014 | |
| NCT02471209 | Completed | Biliary Atresia, Hepatic Buffer Response and Sevoflurane | January 2012 | February 2014 | |
| NCT02652533 | Completed | Ultrasound Shear Wave Elastography Evaluation of Suspected and Known Biliary Atresia | September 2016 | July 2019 | |
| NCT03395028 | Completed | Early Phase 1 | GCSF Adjunct Therapy for Biliary Atresia | January 15, 2018 | January 31, 2020 |
| NCT03499249 | Completed | Phase 2 | N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy | May 18, 2018 | March 23, 2024 |
| NCT04524390 | Completed | Phase 2 | Evaluation of Maralixibat in Biliary Atresia Response Post-Kasai | July 8, 2021 | February 7, 2024 |
| NCT04778735 | Completed | N/A | Investigation of Mortality, Morbidity and Risk Factors After Pediatric Liver Transplantation | February 24, 2021 | April 4, 2022 |
| NCT00007033 | Completed | N/A | Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease | October 2000 | |
| NCT05925543 | Completed | Outcome of Kasai Portoenterostomy in Biliary Atresia in Upper Egypt | January 1, 2019 | December 30, 2019 | |
| NCT06163417 | Completed | Laparoscopic Kasai Has Similar Anesthetic Outcomes to Open Kasai | January 1, 2011 | March 28, 2023 | |
| NCT05426733 | Enrolling by invitation | Phase 3 | An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia | July 5, 2022 | December 31, 2026 |
| NCT06260566 | Not yet recruiting | Phase 1 | Tolerability of Enteral NAC in Infants | May 2024 | February 2027 |
| NCT03890536 | Not yet recruiting | Intestinal Microbiome Composition in Infants With Biliary Atresia (BA) | December 2023 | March 2032 | |
| NCT06121375 | Not yet recruiting | Phase 2/Phase 3 | Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy | March 2024 | December 2027 |
| NCT05783518 | Not yet recruiting | Phase 4 | Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients | March 27, 2023 | October 31, 2023 |
| NCT05925309 | Recruiting | N/A | Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy | July 1, 2023 | July 31, 2027 |
| NCT03273049 | Recruiting | Mapping Disease Pathways for Biliary Atresia | July 21, 2016 | July 21, 2027 | |
| NCT03842150 | Recruiting | Development and Validation of a Screening Score for the Biliary Atresia in Infantile Cholestasis: A Prospective Study | June 1, 2014 | December 31, 2025 | |
| NCT05072626 | Recruiting | High Medium-chain Triglyceride Nutritional Support in Infants With Biliary Atresia | October 11, 2021 | December 31, 2026 | |
| NCT05181332 | Recruiting | Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis | January 1, 2021 | December 31, 2024 | |
| NCT05399745 | Recruiting | BILACO Trial: Biliary Atresia - a Severe Complex Congenital Liver Disease | March 1, 2020 | December 31, 2040 | |
| NCT00345553 | Recruiting | Biliary Atresia Study in Infants and Children | May 16, 2006 | May 2029 | |
| NCT05464303 | Recruiting | Definition for Biliary Atresia Associated Cholangitis After Surgery | July 15, 2022 | December 31, 2022 | |
| NCT00061828 | Recruiting | A Prospective Database of Infants With Cholestasis | April 21, 2004 | May 2029 | |
| NCT05521152 | Recruiting | Phase 3 | Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy | May 1, 2022 | April 1, 2024 |
| NCT01793168 | Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | July 2010 | December 2100 | |
| NCT02137668 | Recruiting | Phase 1 | Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin | July 2010 | July 2028 |
| NCT05848310 | Recruiting | Preoperative Serum FGF19 in the Prognosis of Biliary Atresia | October 15, 2023 | August 2024 | |
| NCT05909033 | Recruiting | Early Predictors for the Short Term Native Liver Survival in Patients With Biliary Atresia After Kasai Procedure | May 20, 2017 | July 1, 2023 | |
| NCT04272515 | Recruiting | N/A | Molecular Characterization for Understanding Biliary Atresia | February 7, 2021 | February 7, 2032 |
| NCT04336722 | Recruiting | Phase 3 | Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD) | July 8, 2020 | July 31, 2026 |
| NCT04373941 | Recruiting | Phase 2 | Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia | September 1, 2023 | October 31, 2025 |
| NCT06447051 | Recruiting | Efficacy of New Post Kasai ILBS Protocol in Biliary Atresia. | June 6, 2024 | March 31, 2026 | |
| NCT06184971 | Recruiting | Biliary Atresia Research Network Northeast | May 6, 2024 | December 2024 | |
| NCT01774487 | Terminated | Phase 2 | Pentoxifylline Therapy in Biliary Atresia | February 4, 2013 | February 20, 2023 |
| NCT05321524 | Terminated | Phase 2 | Obeticholic Acid in Pediatric Subjects With Biliary Atresia | July 1, 2015 | March 9, 2023 |
| NCT03898765 | Unknown status | N/A | Dry Blood Spot Screening Test for Biliary Atresia（DBS-SCReBA） | April 1, 2019 | December 31, 2021 |
| NCT04506021 | Unknown status | A Real World Study on Clinical Efficacy of Bicarbonate Ringer's Solution in Biliary Atresia Children | August 2020 | October 2021 | |
| NCT04260503 | Unknown status | Gut Microbiome in Biliary Atresia | May 21, 2019 | May 20, 2022 | |
| NCT02503384 | Unknown status | Clinical and Basic Study for Pediatric Liver Transplantation | July 2015 | September 2018 | |
| NCT04961034 | Unknown status | N/A | Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop | January 2015 | December 20, 2023 |
| NCT03667534 | Unknown status | Dry Blood Spot Screening Test for Neonatal Cholestasis Patients | September 9, 2018 | September 9, 2021 | |
| NCT00155194 | Unknown status | Evaluation of Immune Function in Biliary Atresia Children With Prolonged Jaundice | April 2004 | ||
| NCT00539565 | Unknown status | Phase 3 | RCT of Steroids Following Kasai Portoenterostomy for Biliary Atresia. | January 2000 | September 2008 |
| NCT01745991 | Unknown status | Trail to Investigate the Effectiveness of CoSeal in Reducing Adhesions Following the Kasai Hepatoportoenterostomy for Biliary Atresia | December 2012 | December 2017 |
- Disase is a (Disease Ontology)
- DOID:13580
- Cross Reference ID (Disease Ontology)
- GARD:12010
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q44.2
- Cross Reference ID (Disease Ontology)
- ICD9CM:751.61
- Cross Reference ID (Disease Ontology)
- MESH:D001656
- Cross Reference ID (Disease Ontology)
- MIM:210500
- Cross Reference ID (Disease Ontology)
- NCI:C34421
- Cross Reference ID (Disease Ontology)
- ORDO:30391
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:77480004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0005411
- Exact Synonym (Disease Ontology)
- Atresia of bile duct
- Exact Synonym (Disease Ontology)
- biliary atresia, congenital
- Exact Synonym (Disease Ontology)
- Congenital biliary atresia
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0005912
- MeSH unique ID (MeSH (Medical Subject Headings))
- D001656